Childhood victimization and inflammation in young adulthood: A genetically sensitive cohort study

Brain, Behavior, and Immunity

Volumn 67, Issue , 2018, Pages 211-217

  Baldwin, Jessie R ^a   Arseneault, Louise ^a   Caspi, Avshalom ^a,b,c   Fisher, Helen L ^a   Moffitt, Terrie E ^a,b,c   Odgers, Candice L ^b,c,d   Pariante, Carmine ^e   Ambler, Antony ^a   Dove, Rosamund ^a   Kepa, Agnieszka ^a   Matthews, Timothy ^a   Menard, Anne ^a   Sugden, Karen ^b   Williams, Benjamin ^b   Danese, Andrea ^a,e,f  

^a MEDICAL RESEARCH COUNCIL   (United Kingdom)

^b DUKE UNIVERSITY   (United States)

^c DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e KING'S COLLEGE LONDON   (United Kingdom)

^f SOUTH LONDON AND MAUDSLEY NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Bullying victimization; C reactive protein; Childhood maltreatment; Childhood victimization; Early life stress; Inflammation; Sex differences

Indexed keywords

C REACTIVE PROTEIN; BIOLOGICAL MARKER;

ADULT; ARTICLE; BEHAVIOR DISORDER; BODY TEMPERATURE; CHILD; CHILDHOOD VICTIMIZATION; COHORT ANALYSIS; DISEASE ASSESSMENT; DISEASE ASSOCIATION; DIZYGOTIC TWINS; DRIED BLOOD SPOT TESTING; EXPOSURE; FEMALE; GENETIC ANALYSIS; HUMAN; INFLAMMATION; LONGITUDINAL STUDY; MALE; MONOZYGOTIC TWINS; PRESCHOOL CHILD; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; RISK FACTOR; SCHOOL CHILD; SOCIAL STATUS; TWIN STUDY; WAIST HIP RATIO; YOUNG ADULT; ADOLESCENT; BLOOD; CHILD ABUSE; CHILD ABUSE SURVIVOR; GENETIC PREDISPOSITION; GENETICS; METABOLISM; STATISTICS AND NUMERICAL DATA; TWINS;

ADOLESCENT; ADULT SURVIVORS OF CHILD ABUSE; BIOMARKERS; C-REACTIVE PROTEIN; CHILD ABUSE; COHORT STUDIES; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INFLAMMATION; MALE; PROSPECTIVE STUDIES; RISK FACTORS;

EID: 85032193989     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2017.08.025     Document Type: Article

References (55)

1. Arseneault, L., Cannon, M., Fisher, H.L., Polanczyk, G., Moffitt, T.E., Caspi, A., Childhood trauma and children's emerging psychotic symptoms: a genetically sensitive longitudinal cohort study. Am. J. Psychiatry 168 (2011), 65–72.
2. Baldwin, J.R., Arseneault, L., Odgers, C., Belsky, D.W., Matthews, T., Ambler, A., Caspi, A., Moffitt, T.E., Danese, A., Childhood bullying victimization and overweight in young adulthood: a cohort study. Psychosom. Med. 78 (2016), 1094–1103.
3. Bale, T.L., Epperson, C.N., Sex differences and stress across the lifespan. Nat. Neurosci. 18 (2015), 1413–1420.
4. Baumeister, D., Akhtar, R., Ciufolini, S., Pariante, C., Mondelli, V., Childhood trauma and adulthood inflammation: a meta-analysis of peripheral C-reactive protein, interleukin-6 and tumour necrosis factor-α. Mol. Psychiatry 21 (2015), 642–649.
5. Brooks, G.C., Blaha, M.J., Blumenthal, R.S., Relation of C-reactive protein to abdominal adiposity. Am. J. Cardiol. 106 (2010), 56–61.
6. Cole, S.W., Conti, G., Arevalo, J.M., Ruggiero, A.M., Heckman, J.J., Suomi, S.J., Transcriptional modulation of the developing immune system by early life social adversity. Proc. Natl. Acad. Sci. 109 (2012), 20578–20583.
7. Copeland, W.E., Wolke, D., Lereya, S.T., Shanahan, L., Worthman, C., Costello, E.J., Childhood bullying involvement predicts low-grade systemic inflammation into adulthood. Proc. Natl. Acad. Sci. 111 (2014), 7570–7575.
8. Creswell, J.D., Irwin, M.R., Burklund, L.J., Lieberman, M.D., Arevalo, J.M.G., Ma, J., Breen, E.C., Cole, S.W., Mindfulness-based stress reduction training reduces loneliness and pro-inflammatory gene expression in older adults: a small randomized controlled trial. Brain Behav. Immun. 26 (2012), 1095–1101.
9. Danese, A., Baldwin, J.R., Hidden wounds? Inflammatory links between childhood trauma and psychopathology. Annu. Rev. Psychol. 68 (2017), 517–544.
10. Danese, A., Caspi, A., Williams, B., Ambler, A., Sugden, K., Mika, J., Werts, H., Freeman, J., Pariante, C., Moffitt, T., Biological embedding of stress through inflammation processes in childhood. Mol. Psychiatry 16 (2011), 244–246.
11. Danese, A., McCrory, E., Child maltreatment. Thapar, A., Pine, D.S., Leckman, J.F., Scott, S., Snowling, M.J., Taylor, E., (eds.) Rutter's Child and Adolescent Psychiatry, 2015, Wiley Blackwell, London.
12. Danese, A., McEwen, B.S., Adverse childhood experiences, allostasis, allostatic load, and age-related disease. Physiol. Behav. 106 (2012), 29–39.
13. Danese, A., Moffitt, T.E., Arseneault, L., Bleiberg, B.A., Dinardo, P.B., Gandelman, S.B., Houts, R., Ambler, A., Fisher, H.L., Poulton, R., The origins of cognitive deficits in victimized children: implications for neuroscientists and clinicians. Am. J. Psychiatry 174 (2016), 349–361.
14. Danese, A., Moffitt, T.E., Harrington, H., Milne, B.J., Polanczyk, G., Pariante, C.M., Poulton, R., Caspi, A., Adverse childhood experiences and adult risk factors for age-related disease: depression, inflammation, and clustering of metabolic risk markers. Arch. Pediatr. Adolesc. Med., 163, 2009, 1135.
15. Danese, A., Pariante, C.M., Caspi, A., Taylor, A., Poulton, R., Childhood maltreatment predicts adult inflammation in a life-course study. Proc. Natl. Acad. Sci. 104 (2007), 1319–1324.
16. Danese, A., Tan, M., Childhood maltreatment and obesity: systematic review and meta-analysis. Mol. Psychiatry 19 (2014), 544–554.
17. Dehghan, A., Dupuis, J., Barbalic, M., Bis, J.C., Eiriksdottir, G., Lu, C., Pellikka, N., Wallaschofski, H., Kettunen, J., Henneman, P., Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. Circulation 123 (2011), 731–738.
18. Delpech, J.-C., Wei, L., Hao, J., Yu, X., Madore, C., Butovsky, O., Kaffman, A., Early life stress perturbs the maturation of microglia in the developing hippocampus. Brain Behav. Immun. 57 (2016), 79–93.
19. Finkelhor, D., Ormrod, R.K., Turner, H.A., Poly-victimization: a neglected component in child victimization. Child Abuse Negl. 31 (2007), 7–26.
20. Ganguly, P., Brenhouse, H.C., Broken or maladaptive? Altered trajectories in neuroinflammation and behavior after early life adversity. Dev. Cognit. Neurosci. 11 (2015), 18–30.
21. Giugliano, D., Ceriello, A., Esposito, K., The effects of diet on inflammation: emphasis on the metabolic syndrome. J. Am. Coll. Cardiol. 48 (2006), 677–685.
22. Gleeson, M., Bishop, N.C., Stensel, D.J., Lindley, M.R., Mastana, S.S., Nimmo, M.A., The anti-inflammatory effects of exercise: mechanisms and implications for the prevention and treatment of disease. Nat. Rev. Immunol., 11, 2011, 607.
23. Howe, L., Galobardes, B., Sattar, N., Hingorani, A., Deanfield, J., Ness, A., Davey-Smith, G., Lawlor, D., Are there socioeconomic inequalities in cardiovascular risk factors in childhood, and are they mediated by adiposity? Findings from a prospective cohort study. Int. J. Obesity 34 (2010), 1149–1159.
24. Irwin, M.R., Olmstead, R., Breen, E.C., Witarama, T., Carrillo, C., Sadeghi, N., Arevalo, J.M., Ma, J., Nicassio, P., Bootzin, R., Cognitive behavioral therapy and tai chi reverse cellular and genomic markers of inflammation in late-life insomnia: a randomized controlled trial. Biol. Psychiatry 78 (2015), 721–729.
25. Jaffee, S.R., Caspi, A., Moffitt, T.E., Dodge, K.A., Rutter, M., Taylor, A., Tully, L.A., Nature× nurture: genetic vulnerabilities interact with physical maltreatment to promote conduct problems. Dev. Psychopathol. 17 (2005), 67–84.
26. Jaffee, S.R., Price, T.S., Gene–environment correlations: a review of the evidence and implications for prevention of mental illness. Mol. Psychiatry 12 (2007), 432–442.
27. Kendler, K., Kessler, R., Walters, E., MacLean, C., Neale, M., Heath, A., Eaves, L., Stressful life events, genetic liability, and onset of an episode of major depression in women. Am. J. Psychiatry 152 (1995), 833–842.
28. Lereya, S.T., Copeland, W.E., Costello, E.J., Wolke, D., Adult mental health consequences of peer bullying and maltreatment in childhood: two cohorts in two countries. Lancet Psychiatry 2 (2015), 524–531.
29. McDade, T.W., Burhop, J., Dohnal, J., High-sensitivity enzyme immunoassay for C-reactive protein in dried blood spots. Clin. Chem. 50 (2004), 652–654.
30. Merck, 2006. The Merck Manual of Diagnosis and Therapy, Merck Manuals.
31. Miller, G., Chen, E., Cole, S.W., Health psychology: developing biologically plausible models linking the social world and physical health. Annu. Rev. Psychol. 60 (2009), 501–524.
32. Miller, G.E., Cole, S.W., Clustering of depression and inflammation in adolescents previously exposed to childhood adversity. Biol. Psychiatry 72 (2012), 34–40.
33. Moffitt, T.E., E-Risk Study Team, Teen-aged mothers in contemporary Britain. J. Child Psychol. Psychiatry 43 (2002), 727–742.
34. Mohamed-Ali, V., Goodrick, S., Rawesh, A., Katz, D., Miles, J.M., Yudkin, J., Klein, S., Coppack, S., Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-α, in vivo 1. J. Clin. Endocrinol. Metab. 82 (1997), 4196–4200.
35. Murphy, M.O., Loria, A.S., 2017. Sex-specific effects of stress on metabolic and cardiovascular disease: Are women at a higher risk? Am. J. Physiol.-Regul. Integr. Comp. Physiol., Published online 3 May 2017, https://doi.org/10.1152/ajpregu.00185.2016.
36. Odgers, C.L., Caspi, A., Russell, M.A., Sampson, R.J., Arseneault, L., Moffitt, T.E., Supportive parenting mediates neighborhood socioeconomic disparities in children's antisocial behavior from ages 5 to 12. Dev. Psychopathol. 24 (2012), 705–721.
37. Pankow, J.S., Folsom, A.R., Cushman, M., Borecki, I.B., Hopkins, P.N., Eckfeldt, J.H., Tracy, R.P., Familial and genetic determinants of systemic markers of inflammation: the NHLBI family heart study. Atherosclerosis 154 (2001), 681–689.
38. Pearson, T.A., Mensah, G.A., Alexander, R.W., Anderson, J.L., Cannon, R.O., Criqui, M., Fadl, Y.Y., Fortmann, S.P., Hong, Y., Myers, G.L., Markers of inflammation and cardiovascular disease application to clinical and public health practice: a statement for healthcare professionals from the centers for disease control and prevention and the American Heart Association. Circulation 107 (2003), 499–511.
39. Rathmann, W., Haastert, B., Giani, G., Koenig, W., Imhof, A., Herder, C., Holle, R., Mielck, A., Is inflammation a causal chain between low socioeconomic status and type 2 diabetes? Results from the KORA Survey 2000. Eur. J. Epidemiol. 21 (2006), 55–60.
40. Rohleder, N., Schommer, N.C., Hellhammer, D.H., Engel, R., Kirschbaum, C., Sex differences in glucocorticoid sensitivity of proinflammatory cytokine production after psychosocial stress. Psychosom. Med. 63 (2001), 966–972.
41. Rooks, C., Veledar, E., Goldberg, J., Bremner, J.D., Vaccarino, V., Early trauma and inflammation: role of familial factors in a study of twins. Psychosom. Med., 74, 2012, 146.
42. Shanahan, L., Copeland, W.E., Worthman, C.M., Erkanli, A., Angold, A., Costello, E.J., Sex-differentiated changes in C-reactive protein from ages 9 to 21: the contributions of BMI and physical/sexual maturation. Psychoneuroendocrinology 38 (2013), 2209–2217.
43. Shonkoff, J.P., Boyce, W.T., McEwen, B.S., Neuroscience, molecular biology, and the childhood roots of health disparities: building a new framework for health promotion and disease prevention. JAMA 301 (2009), 2252–2259.
44. Slopen, N., Kubzansky, L.D., McLaughlin, K.A., Koenen, K.C., Childhood adversity and inflammatory processes in youth: a prospective study. Psychoneuroendocrinology 38 (2013), 188–200.
45. Steptoe, A., Owen, N., Kunz-Ebrecht, S., Mohamed-Ali, V., Inflammatory cytokines, socioeconomic status, and acute stress responsivity. Brain Behav. Immun. 16 (2002), 774–784.
46. Sugden, K., Danese, A., Shalev, I., Williams, B.S., Caspi, A., Blood substrate collection and handling procedures under pseudo-field conditions: evaluation of suitability for inflammatory biomarker measurement. Biodemography Soc. Biol. 61 (2015), 273–284.
47. Takizawa, R., Danese, A., Maughan, B., Arseneault, L., Bullying victimization in childhood predicts inflammation and obesity at mid-life: a five-decade birth cohort study. Psychol. Med. 45 (2015), 1–11.
48. Takizawa, R., Maughan, B., Arseneault, L., Adult health outcomes of childhood bullying victimization: evidence from a five-decade longitudinal British birth cohort. Am. J. Psychiatry 171 (2014), 777–784.
49. The Network and Pathway Analysis Subgroup of the Psychiatric Genomics Consortium, Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways. Nat. Neurosci. 18 (2015), 199–209.
50. Trouton, A., Spinath, F.M., Plomin, R., Twins early development study (TEDS): a multivariate, longitudinal genetic investigation of language, cognition and behavior problems in childhood. Twin Res. 5 (2002), 444–448.
51. Trzesniewski, K.H., Moffitt, T.E., Caspi, A., Taylor, A., Maughan, B., Revisiting the association between reading achievement and antisocial behavior: new evidence of an environmental explanation from a twin study. Child Dev. 77 (2006), 72–88.
52. Van Lier, P., Boivin, M., Dionne, G., Vitaro, F., Brendgen, M., Koot, H., Tremblay, R.E., Perusse, D., Kindergarten children's genetic vulnerabilities interact with friends' aggression to promote children's own aggression. J. Am. Acad. Child Adolesc. Psychiatry 46 (2007), 1080–1087.
53. Varese, F., Smeets, F., Drukker, M., Lieverse, R., Lataster, T., Viechtbauer, W., Read, J., van Os, J., Bentall, R.P., Childhood adversities increase the risk of psychosis: a meta-analysis of patient-control, prospective-and cross-sectional cohort studies. Schizophr. Bull. 38 (2012), 661–671.
54. Visser, M., Bouter, L.M., McQuillan, G.M., Wener, M.H., Harris, T.B., Elevated c-reactive protein levels in overweight and obese adults. JAMA 282 (1999), 2131–2135.
55. Wigman, J.T., van Winkel, R., Jacobs, N., Wichers, M., Derom, C., Thiery, E., Vollebergh, W.A., Van Os, J., A twin study of genetic and environmental determinants of abnormal persistence of psychotic experiences in young adulthood. Am. J. Med. Genet. Part B: Neuropsychiatr. Genet. 156 (2011), 546–552.