Inflammatory cytokines, socioeconomic status, and acute stress responsivity

Brain, Behavior, and Immunity

Volumn 16, Issue 6, 2002, Pages 774-784

  Steptoe, Andrew ^a   Owen, Natalie ^a   Kunz Ebrecht, Sabine ^a   Mohamed Ali, Vidya ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Cytokines; Interleukin 1 receptor antagonist; Interleukin 6; Mental stress; Social class; Socioeconomic status; Tumor necrosis factor

Indexed keywords

CYTOKINE; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; BLOOD LEVEL; COHORT ANALYSIS; CONTROLLED STUDY; EMPLOYMENT; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SEX DIFFERENCE; SOCIAL STATUS; STRESS;

ACUTE DISEASE; ADULT; EMPLOYMENT; FEMALE; HUMANS; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-6; MALE; MIDDLE AGED; RISK FACTORS; SEX DISTRIBUTION; SIALOGLYCOPROTEINS; SOCIAL CLASS; STRESS, PSYCHOLOGICAL; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0036924589     PISSN: 08891591     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0889-1591(02)00030-2     Document Type: Article

References (53)

1. Ackerman, K. D., Martino, M., Heyman, R., Moyna, N. M., & Rabin, B. S. (1998). Stressor-induced alteration of cytokine production in multiple sclerosis patients and controls. Psychosom. Med., 60, 484-491.
2. Asai, K., Hiki, N., Mimura, Y., Ogawa, T., Unou, K., & Kaminishi, M. (2001). Gender differences in cytokine secretion by human peripheral blood mononuclear cells: Role of estrogen in modulating LPS-induced cytokine secretion in an ex vivo septic model. Shock, 16, 340-343.
3. Bhagat, K., & Vallance, P. (1997). Inflammatory cytokines impair endothelium-dependent dilatation in human veins in vivo. Circulation, 96, 3042-3047.
4. Biasucci, L. M., Liuzzo, G., Fantuzzi, G., Caligiuri, G., Rebuzzi, A. G., Ginnetti, F., Dinarello, C. A., & Maseri, A. (1999). Increasing levels of interleukin (IL)-1Ra and IL-6 during the first 2 days of hospitalization in unstable angina are associated with increased risk of in-hospital coronary events. Circulation, 99, 2079-2084.
5. Brunner, E., Davey Smith, G., Marmot, M., Canner, R., Beksinska, M., & O'Brien, J. (1996). Childhood social circumstances and psychosocial and behavioural factors as determinants of plasma fibrinogen. Lancet, 347, 1008-1013.
6. Brunner, E. J., Marmot, M. G., Nanchahal, K., Shipley, M. J., Stansfeld, S. A., Juneja, M., & Alberti, K. G. (1997). Social inequality in coronary risk: Central obesity and the metabolic syndrome. Evidence from the Whitehall II study. Diabetologia, 40, 1341-1349.
7. Dinarello, C. A. (1996). Biologic basis for interleukin-1 in disease. Blood, 87, 2095-2147.
8. Dugué, B., Leppanen, E. A., Teppo, A. M., Fyhrquist, F., & Grasbeck, R. (1993). Effects of psychological stress on plasma interleukins-1β and 6, C-reactive protein, tumour necrosis factor-α, anti-diuretic hormone and serum cortisol. Scand. J. Clin. Lab. Invest., 53, 555-561.
9. Gabay, C., Smith, M. F., Eidlen, D., & Arend, W. P. (1997). Interleukin-1 receptor antagonist (IL-1Ra) is an acute-phase protein. J. Clin. Invest., 99, 2930-2940.
10. Ghiadoni, L., Donald, A., Cropley, M., Mullen, M. J., Oakley, G., Taylor, M., O'Connor, G., Betteridge, J., Klein, N., Steptoe, A., & Deanfield, J. E. (2000). Mental stress induces transient endothelial dysfunction in humans. Circulation, 102, 2473-2478.
11. Glass, C. K., & Witztum, J. L. (2001). Atherosclerosis, the road ahead. Cell, 104, 503-516.
12. Haack, M., Reichenberg, A., Kraus, T., Schuld, A., Yirmiya, R., & Pollmacher, T. (2000). Effects of an intravenous catheter on the local production of cytokines and soluble cytokine receptors in healthy men. Cytokine, 12, 694-698.
13. Harris, T. B., Ferrucci, L., Tracy, R. P., Corti, M. C., Wacholder, S., Ettinger, W. H., Jr., Heimovitz, H., Cohen, H. J., & Wallace, R. (1999). Associations of elevated interleukin-6 and C-reactive protein levels with mortality in the elderly. Am. J. Med., 106, 506-512.
14. Hemingway, H., & Marmot, M. (1999). Evidence based cardiology: Psychosocial factors in the aetiology and prognosis of coronary heart disease: Systematic review of prospective cohort studies. Br. Med. J., 318, 1460-1467.
15. Hingorani, A. D., Cross, J., Kharbanda, R. K., Mullen, M. J., Bhagat, K., Taylor, M., Donald, A. E., Palacios, M., Griffin, G. E., Deanfield, J. E., MacAllister, R. J., & Vallance, P. (2000). Acute systemic inflammation impairs endothelium-dependent dilatation in humans. Circulation, 102, 994-999.
16. Kumari, M., Marmot, M., & Brunner, E. (2000). Social determinants of von Willebrand factor: The Whitehall II study. Arterioscler. Thromb. Vasc. Biol., 20, 1842-1847.
17. Libby, P. (2001). Current concepts of the pathogenesis of the acute coronary syndromes. Circulation, 104, 365-372.
18. Lutgendorf, S. K., Garand, L., Buckwalter, K. C., Reimer, T. T., Hong, S.-Y., & Lubaroff, D. M. (1999). Life stress, mood disturbance, and elevated interleukin-6 in healthy older women. J. Gerontol.: Med. Sci., 54A, M434-M439.
19. Lynch, E. A., Dinarello, C. A., & Cannon, J. G. (1994). Gender differences in IL-1α, IL-1β, and IL-1 receptor antagonist secretion from mononuclear cells and urinary excretion. J. Immunol., 153, 300-306.
20. Lynch, J. W., Kaplan, G. A., Salonen, R., Cohen, R. D., & Salonen, J. (1995). Socioeconomic status and carotid atherosclerosis. Circulation, 92, 1786-1792.
21. Maes, M., Song, C., Lin, A., De Jongh, R., Van Gastel, A., Kenis, G., Bosmans, E., De Meester, I., Benoy, I., Neels, H., Demedts, P., Janca, A., Scharpe, S., & Smith, R. S. (1998). The effects of psychological stress on humans: Increased production of proinflammatory cytokines and a Th1-like response in stress-induced anxiety. Cytokine, 10, 313-318.
22. Maes, M., Vandoolaeghe, E., Ranjan, R., Bosmans, E., Bergmans, R., & Desnyder, R. (1995). Increased serum interleukin-1-receptor-antagonist concentrations in major depression. J. Affect. Disord., 36, 29-36.
23. Mandrup-Poulsen, T., Wogensen, L. D., Jensen, M., Svensson, P., Nilsson, P., Emdal, T., Molvig, J., Dinarello, C. A., & Nerup, J. (1995). Circulating interleukin-1 receptor antagonist concentrations are increased in adult patients with thermal injury. Crit. Care Med., 23, 26-33.
24. Marmot, M., & Wilkinson, R. G. (Eds.). (1999). Social Determinants of Health. Oxford: Oxford University Press.
25. Marmot, M. G., Adelstein, A. M., Robinson, N., & Rose, G. A. (1978). Changing social class distribution of heart disease. Br. Med. J, ii, 1109-1112.
26. Marmot, M. G., Davey Smith, G., Stansfeld, S., Patel, C., North, F., Head, J., White, I., Brunner, E., & Feeney, A. (1991). Health inequalities among British civil servants: The Whitehall II study. Lancet, 337, 1387-1393.
27. McCann, S. M., Sternberg, E. M., Lipton, J. M., Chrousos, G. P., Gold, P. W., & Smith, C. C. (Eds.). (1998). Neuroimmunomodulation: Molecular Aspects, Integrative Systems, and Clinical Advances (Vol. 840). New York: Annals of the New York Academy of Sciences.
28. Mendall, M. A. (1997). C-reactive protein response and progression of atherosclerosis: Is atherosclerosis the byproduct of systemic infection? Cardiologia, 42, 1139-1144.
29. Mendall, M. A., Patel, P., Asante, M., Ballam, L., Morris, J., Strachan, D. P., Camm, A. J., & Northfield, T. C. (1997). Relation of serum cytokine concentrations to cardiovascular risk factors and coronary heart disease. Heart, 78, 273-277.
30. Mohamed-Ali, V., Flower, L., Sethi, J., Hotamisligil, G., Gray, R., Humphries, S. E., York, D. A., & Pinkney, J. (2001). β-Adrenergic regulation of IL-6 release from adipose tissue: In vivo and in vitro studies. J. Clin. Endocrinol. Metab., 86, 5864-5869.
31. Mohamed-Ali, V., Goodrick, S., Rawesh, A., Katz, D. R., Miles, J. M., Yudkin, J. S., Klein, S., & Coppack, S. W. (1997). Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-alpha, in vivo. J. Clin. Endocrinol. Metab., 82, 4196-4200.
32. Muldoon, M. F., Bachen, E. A., Manuck, S. B., Waldstein, S. R., Bricker, P. L., & Bennett, J. A. (1992). Acute cholesterol responses to mental stress and change in posture. Arch. Intern. Med., 152, 775-780.
33. Owens, J. F., Stoney, C. M., & Matthews, K. A. (1993). Menopausal status influences ambulatory blood pressure levels and blood pressure changes during mental stress. Circulation, 88, 2794-2802.
34. Patterson, S. M., Marsland, A. L., Manuck, S. B., Kameneva, M., & Muldoon, M. F. (1998). Acute hemoconcentration during psychological stress: Assessment of heorheologic factors. Int. J. Behav. Med., 5, 204-212.
35. Patterson, S. M., Matthews, K. A., Allen, M. T., & Owens, J. F. (1995). Stress-induced hemoconcentration of blood cells and lipids in healthy women during acute psychological stress. Health Psychol., 14, 319-324.
36. Pennebaker, J. W. (1982). The Psychology of Physical Symptoms. New York: Springer-Verlag.
37. Pfeiffer, A., Janott, J., Mohlig, M., Ristow, M., Rochlitz, H., Busch, K., Schatz, H., & Schifferdecker, E. (1997). Circulating tumor necrosis factor-α is elevated in male but not in female patients with type II diabetes mellitus. Horm. Metab. Res., 29, 111-114.
38. Ridker, P. M., Hennekens, C. H., Buring, J. E., & Rifai, N. (2000a). C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. N. Engl. J. Med., 342, 836-843.
39. Ridker, P. M., Rifai, N., Pfeffer, M., Sacks, F., Lepage, S., & Braunwald, E. (2000b). Elevation of tumor necrosis factor-alpha and increased risk of recurrent coronary events after myocardial infarction. Circulation, 101, 2149-2153.
40. Ridker, P. M., Rifai, N., Stampfer, M. J., & Hennekens, C. H. (2000c). Plasma concentration of interleukin-6 and the risk of future myocardial infarction among apparently healthy men. Circulation, 101, 1767-1772.
41. Rohleder, N., Schommer, N. C., Hellhammer, D. H., Engel, R., & Kirschbaum, C. (2001). Sex differences in glucocorticoid sensitivity of proinflammatory cytokine production after psychosocial stress. Psychosom. Med., 63, 966-972.
42. Ross, R. (1999). Atherosclerosis - An inflammatory disease. N. Engl. J. Med., 340, 115-126.
43. Song, C., Kenis, G., van Gastel, A., Bosmans, E., Lin, A., de Jong, R., Neels, H., Scharpe, S., Janca, A., Yasukawa, K., & Maes, M. (1999). Influence of psychological stress on immune-inflammatory variables in normal humans. Part II. Altered serum concentrations of natural anti-inflammatory agents and soluble membrane antigens of monocytes and T lymphocytes. Psychiatry Res., 85, 293-303.
44. Steptoe, A., Willemsen, G., Owen, N., Flower, L., & Mohamed-Ali, V. (2001). Acute mental stress elicits delayed increases in circulating inflammatory cytokine levels. Clin. Sci., 101, 185-192.
45. Steptoe, A., Feldman, P. J., Kunz, S., Owen, N., Willemsen, G., & Marmot, M. (in press). Stress responsivity and socioeconomic status: A mechanism for increased cardiovascular disease risk? Eur. Heart J.
46. Straub, R. H., Hense, H. W., Andus, T., Scholmerich, J., Riegger, G. A., & Schunkert, H. (2000). Hormone replacement therapy and interrelation between serum interleukin-6 and body mass index in postmenopausal women: A population-based study. J. Clin. Endocrinol. Metab., 85, 1340-1344.
47. Theorell, T., Hasselhorn, H.-M., Vingard, E., & Andersson, B. (2000). Interluekin6 and cortisol in acute musculoskeletal disorders: Results from a case-referent study in Sweden. Stress Med., 16, 27-35.
48. Verthelyi, D., & Klinman, D. M. (2000). Sex hormone levels correlate with the activity of cytokine-secreting cells in vivo. Immunology, 100, 384-390.
49. Volpato, S., Guralnik, J. M., Ferrucci, L., Balfour, J., Chaves, P., Fried, L. P., & Harris, T. B. (2001). Cardiovascular disease, interleukin-6, and risk of mortality in older women: The women's health and aging study. Circulation, 103, 947-953.
50. Woodward, M., Rumley, A., Tunstall-Pedoe, H., & Lowe, G. D. (1999). Associations of blood rheology and interleukin-6 with cardiovascular risk factors and prevalent cardiovascular disease. Br. J. Haematol., 104, 246-257.
51. Young, D. G., Skibinski, G., Mason, J. I., & James, K. (1999). The influence of age and gender on serum dehydroepiandrosterone sulphate (DHEA-S), IL-6, IL-6 soluble receptor (IL-6 sR) and transforming growth factor-β1 TGF-β1 levels in normal healthy blood donors. Clin. Exp. Immunol., 117, 476-481.
52. Yudkin, J. S., Kumari, M., Humphries, S. E., & Mohamed-Ali, V. (2000). Inflammation, obesity, stress and coronary heart disease: Is interleukin-6 the link? Atherosclerosis, 148, 209-214.
53. Yudkin, J. S., Yajnik, C. S., Mohamed-Ali, V., & Bulmer, K. (1999). High levels of circulating proinflammatory cytokines and leptin in urban, but not rural, Indians. A potential explanation for increased risk of diabetes and coronary heart disease. Diabetes Care, 22, 363-364.