Childhood adversity and inflammatory processes in youth: A prospective study

Psychoneuroendocrinology

Volumn 38, Issue 2, 2013, Pages 188-200

  Slopen, Natalie ^a,b,c   Kubzansky, Laura D ^b   McLaughlin, Katie A ^a,d,e   Koenen, Karestan C ^f  

^a HARVARD UNIVERSITY   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c HARVARD GRADUATE SCHOOL OF EDUCATION   (United States)

^d BOSTON CHILDREN S HOSPITAL   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

^f Columbia University ^*  (United States)

Author keywords

Acute stress; Adolescents; Avon Longitudinal Study of Parents and Children (ALSPAC); C reactive protein; Children; Inflammation; Interleukin 6; Prospective cohort; Stressful life events

Indexed keywords

C REACTIVE PROTEIN; INTERLEUKIN 6;

ADOLESCENT; ARTICLE; BODY MASS; CHILD; CHILDHOOD; CHILDHOOD ADVERSITY; DEPRESSION; EARLY LIFE STRESS; EXPERIENCE; FEMALE; HUMAN; INFLAMMATION; LIFE EVENT; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROSPECTIVE STUDY; SCHOOL CHILD; SMOKING;

ADOLESCENT; AGE FACTORS; BODY MASS INDEX; C-REACTIVE PROTEIN; CHILD; DEPRESSION; FEMALE; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN-6; LIFE CHANGE EVENTS; MALE; PROSPECTIVE STUDIES;

EID: 84872862667     PISSN: 03064530     EISSN: 18733360     Source Type: Journal    
DOI: 10.1016/j.psyneuen.2012.05.013     Document Type: Article

References (70)

1. Allen J., Rapee R., Sandberg S. Assessment of maternally reported life events in children and adolescents: a comparison of interview and checklist methods. J. Psychopathol. Behav. 2011, 1-12.
2. Angold A., Costello E.J., Messer S.C., Pickles A., Winder F., Silver D. Development of a short questionnaire for use in epidemiological studies of depression in children and adolescents. Int. J. Methods Psychiatr. Res. 1995, 5:237-249.
3. Angold A., Erkanli A., Silberg J., Eaves L., Costello E.J. Depression scale scores in 8-17-year-olds: effects of age and gender. J. Child Psychol. Psyc. 2002, 43:1052-1063.
4. C Reactive Protein Coronary Heart Disease Genetics Collaboration Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data. BMJ 2011, 342.
5. Casas J.P., Shah T., Cooper J., Hawe E., McMahon A.D., Gaffney D., Packard C.J., O'Reilly D.S., Juhan-Vague I., Yudkin J.S., Tremoli E., Margaglione M., Di Minno G., Hamsten A., Kooistra T., Stephens J.W., Hurel S.J., Livingstone S., Colhoun H.M., Miller G.J., Bautista L.E., Meade T., Sattar N., Humphries S.E., Hingorani A.D. Insight into the nature of the CRP-coronary event association using Mendelian randomization. Int. J. Epidemiol. 2006, 35:922-931.
6. Caserta M.T., O'Connor T.G., Wyman P.A., Wang H., Moynihan J., Cross W., Tu X., Jin X. The associations between psychosocial stress and the frequency of illness, and innate and adaptive immune function in children. Brain Behav. Immun. 2008, 22:933-940.
7. Chapman D.P., Whitfield C.L., Felitti V.J., Dube S.R., Edwards V.J., Anda R.F. Adverse childhood experiences and the risk of depressive disorders in adulthood. J. Affect Disorders 2004, 82:217-225.
8. Cook D.G., Mendall M.A., Whincup P.H., Carey I.M., Ballam L., Morris J.E., Miller G.J., Strachan D.P. C-reactive protein concentration in children: relationship to adiposity and other cardiovascular risk factors. Atherosclerosis 2000, 149:139-150.
9. Copeland W.E., Shanahan L., Worthman C., Angold A., Costello E.J. Cumulative depression episodes predict later C-reactive protein levels: a prospective analysis. Biol. Psychiatr. 2012, 71:15-21.
10. Cox J.L., Holden J.M., Sagovsky R. Detection of postnatal depression development of the 10-item Edinburgh Postnatal Depression Scale. Br. J. Psychiatr. 1987, 150:782-786.
11. Danese A., Caspi A., Williams B., Ambler A., Sugden K., Mika J., Werts H., Freeman J., Pariante C.M., Moffitt T.E., Arseneault L. Biological embedding of stress through inflammation processes in childhood. Mol. Psychiatr. 2011, 16:244-246.
12. Danese A., Moffitt T.E., Harrington H., Milne B.J., Polanczyk G., Pariante C.M., Poulton R., Caspi A. Adverse Childhood Experiences and Adult Risk Factors for Age-Related Disease Depression Inflammation, and Clustering of Metabolic Risk Markers. Arch. Pediat. Adol. Med. 2009, 163:1135-1143.
13. Danese A., Moffitt T.E., Pariante C.M., Ambler A., Poulton R., Caspi A. Elevated inflammation levels in depressed adults with a history of childhood maltreatment. Arch. Gen. Psychiatry 2008, 65:409-415.
14. Danese A., Pariante C.M., Caspi A., Taylor A., Poulton R. Childhood maltreatment predicts adult inflammation in a life-course study. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:1319-1324.
15. Danesh J., Wheeler J.G., Hirschfield G.M., Eda S., Eiriksdottir G., Rumley A., Lowe G.D.O., Pepys M.B., Gudnason V. C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease. N. Engl. J. Med. 2004, 350:1387-1397.
16. Dixon D., Meng H., Goldberg R., Schneiderman N., Delamater A. Stress and body mass index each contributes independently to tumor necrosis factor-[alpha] production in prepubescent Latino Children. J. Pediatr. Nurs. 2009, 24:378-388.
17. Dong M., Giles W.H., Felitti V.J., Dube S.R., Williams J.E., Chapman D.P., Anda R.F. Insights into causal pathways for ischemic heart disease: adverse childhood experiences study. Circulation 2004, 110:1761-1766.
18. Dowd J.B., Zajacova A., Aiello A.E. Predictors of inflammation in U.S. children aged 3-16 years. Am. J. Prev. Med. 2010, 39:314-320.
19. Dube S.R., Fairweather D., Pearson W.S., Felitti V.J., Anda R.F., Croft J.B. Cumulative childhood stress and autoimmune diseases in adults. Psychosom. Med. 2009, 71:243-250.
20. Enoch M.A., Steer C.D., Newman T.K., Gibson N., Goldman D. Early life stress, MAOA, and gene-environment interactions predict behavioral disinhibition in children. Genes Brain Behav. 2010, 9:65-74.
21. Felitti V.J., Anda R.F., Nordenberg D., Williamson D.F., Spitz A.M., Edwards V., Koss M.P., Marks J.S. Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults The Adverse Childhood Experiences (ACE) Study. Am. J. Prev. Med. 1998, 14:245-258.
22. Fuligni A.J., Telzer E.H., Bower J., Cole S.W., Kiang L., Irwin M.R. A preliminary study of daily interpersonal stress and C-reactive protein levels among adolescents from Latin American and European backgrounds. Psychosom. Med. 2009, 71:329-333.
23. Fuligni A.J., Telzer E.H., Bower J., Irwin M.R., Kiang L., Cole S.W. Daily family assistance and inflammation among adolescents from Latin American and European backgrounds. Brain Behav. Immun. 2009, 23:803-809.
24. Galobardes B., Smith G.D., Lynch J.W. Systematic review of the influence of childhood socioeconomic circumstances on risk for cardiovascular disease in adulthood. Ann. Epidemiol. 2006, 16:91-104.
25. Gimeno D., Ferrie J.E., Elovainio M., Pulkki-Raback L., Keltikangas-Jarvinen L., Eklund C., Hurme M., Lehtimaki T., Marniemi J., Viikari J.S.A., Raitakari O.T., Kivimaki M. When do social inequalities in C-reactive protein start?. A life course perspective from conception to adulthood in the Cardiovascular Risk in Young Finns Study. Int. J. Epidemiol. 2008, 37:290-298.
26. Golding J., Pembrey M., Jones R., the Alspac Study Team ALSPAC-The Avon Longitudinal Study of Parents and Children. Paediatri. Perinatal Epidemiol. 2001, 15:74-87.
27. Golding J., the ALSPAC Study Team The Avon Longitudinal Study of Parents and Children (ALSPAC)--study design and collaborative opportunities. Eur. J. Endocrinol. 2004, 151:U119-U123.
28. Goodman R. Psychometric properties of the strengths and difficulties questionnaire. J. Am. Acad. Child Adol. Psyc. 2001, 40:1337-1345.
29. Goodman R., Ford T., Richards H., Gatward R., Meltzer H. The development and well-being assessment: description and initial validation of an integrated assessment of child and adolescent psychopathology. J. Child Psychol. Psyc. 2000, 41:645-655.
30. Grant K.E., Compas B.E., Thurm A.E., McMahon S.D., Gipson P.Y. Stressors and child and adolescent psychopathology: measurement issues and prospective effects. J. Clin. Child Adolesc. Psychol. 2004, 33:412-425.
31. Gundersen C., Mahatmya D., Garasky S., Lohman B. Linking psychosocial stressors and childhood obesity. Obes. Rev. 2011, 12:e54-e63.
32. Howe L.D., Galobardes B., Sattar N., Hingorani A.D., Deanfield J., Ness A.R., Davey-Smith G., Lawlor D.A. Are there socioeconomic inequalities in cardiovascular risk factors in childhood, and are they mediated by adiposity? Findings from a prospective cohort study. Int. J. Obesity 2010, 34:1149-1159.
33. Howren M.B., Lamkin D.M., Suls J. Associations of depression with C-reactive protein IL-1, and IL-6: a meta-analysis. Psychosom. Med. 2009, 71:171-186.
34. Jarvisalo M.J., Harmoinen A., Hakanen M., Paakunainen U., Viikari J., Hartiala J., Lehtimaki T., Simell O., Raitakari O.T. Elevated serum C-reactive protein levels and early arterial changes in healthy children. Arterioscl. Throm. Vas. 2002, 22:1323-1328.
35. Juonala M., Viikari J.S.A., Ronnemaa T., Taittonen L., Marniemi J., Raitakari O.T. Childhood C-reactive protein in predicting CRP and carotid intima-media thickness in adulthood - The Cardiovascular Risk in Young Finns Study. Arterioscl. Throm. Vas. 2006, 26:1883-1888.
36. Kaptoge S., Di Angelantonio E., Lowe G., Pepys M.B., Thompson S.G., Collins R., Danesh J. C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis. Lancet 2010, 375:132-140.
37. Kessler R.C., McLaughlin K.A., Green J.G., Gruber M.J., Sampson N.A., Zaslavsky A.M., Aguilar-Gaxiola S., Alhamzawi A.O., Alonso J., Angermeyer M., Benjet C., Bromet E., Chatterji S., de Girolamo G., Demyttenaere K., Fayyad J., Florescu S., Gal G., Gureje O., Haro J.M., Hu C.Y., Karam E.G., Kawakami N., Lee S., Lepine J.P., Ormel J., Posada-Villa J., Sagar R., Tsang A., Ustun T.B., Vassilev S., Viana M.C., Williams D.R. Childhood adversities and adult psychopathology in the WHO World Mental Health Surveys. Br. J. Psychiatr. 2010, 197:378-385.
38. Kleinbaum D.G., Kupper L.L., Morgenstern H. Epidemiologic Research: Principles and Quantitative Methods 1982, John Wiley and Sons, Belmont, CA.
39. Marin T.J., Martin T.M., Blackwell E., Stetler C., Miller G.E. Differentiating the impact of episodic and chronic stressors on hypothalamic-pituitary-adrenocortical axis regulation in young women. Health Psychol. 2007, 26:447-455.
40. Mathews A., MacLeod C. Cognitive vulnerability to emotional disorders. Annu. Rev. Clin. Psychol. 2005, 1:167-195.
41. McDade T.W., Leonard W.R., Burhop J., Reyes-Garcia V., Vadez V., Huanca T., Godoy R.A. Predictors of C-reactive protein in Tsimane' 2 to 15 year-olds in lowland Bolivia. Am. J. Phys. Anthropol. 2005, 128:906-913.
42. Miller G., Chen E. Unfavorable socioeconomic conditions in early life presage expression of proinflammatory phenotype in adolescence. Psychosom. Med. 2007, 69:402-409.
43. Miller G., Chen E., Cole S.W. Health psychology: developing biologically plausible models linking the social world and physical health. Annu. Rev. Psychol. 2009, 60:501-524.
44. Miller G.E., Chen E. Harsh family climate in early life presages the emergence of a proinflammatory phenotype in adolescence. Psychol. Sci. 2010, 21:848-856.
45. Miller G.E., Rohleder N., Cole S.W. Chronic interpersonal stress predicts activation of pro- and anti-inflammatory signaling pathways 6 months later. Psychosom. Med. 2009, 71:57-62.
46. Murasko J.E. Male-female differences in the association between socioeconomic status and atherosclerotic risk in adolescents. Soc. Sci. Med. 2008, 67:1889-1897.
47. Nazmi A., Oliveira I.O., Horta B.L., Gigante D.P., Victora C.G. Lifecourse socioeconomic trajectories and C-reactive protein levels in young adults: Findings from a Brazilian birth cohort. Soc. Sci. Med. 2010, 70:1229-1236.
48. O'Connor M.F., Bower J.E., Cho H.J., Creswell J.D., Dimitrov S., Hamby M.E., Hoyt M.A., Martin J.L., Robles T.F., Sloan E.K., Thomas K.S., Irwin M.R. To assess, to control, to exclude: effects of biobehavioral factors on circulating inflammatory markers. Brain Behav. Immun. 2009, 23:887-897.
49. Patton G.C., Olsson C., Bond L., Toumbourou J.W., Carlin J.B., Hemphill S.A., Catalano R.F. Predicting female depression across puberty: a two-nation longitudinal study. J. Am. Acad. Child Adolesc. Psychiatr. 2008, 47:1424-1432.
50. Paykel E.S. Methodological aspects of life events research. J. Psychosom. Res. 1983, 27:341-352.
51. Pearson T.A., Mensah G.A., Alexander R.W., Anderson J.L., Cannon R.O., Criqui M., Fadl Y.Y., Fortmann S.P., Hong Y., Myers G.L., Rifai N., Smith S.C., Taubert K., Tracy R.P., Vinicor F. Markers of inflammation and cardiovascular disease application to clinical and public health practice - a statement for healthcare professionals from the centers for disease control and prevention and the American Heart Association. Circulation 2003, 107:499-511.
52. Pervanidou P., Margeli A., Lazaropoulou C., Papassotiriou I., Chrousos G.P. The immediate and long-term impact of physical and/or emotional stress from motor vehicle accidents on circulating stress hormones and adipo-cytokines in children and adolescents. Stress: Int. J. Biol. Stress 2008, 11:438-447.
53. Pollitt R.A., Kaufman J.S., Rose K.M., Diez-Roux A.V., Zeng D., Heiss G. Early-life and adult socioeconomic status and inflammatory risk markers in adulthood. Eur. J. Epidemiol. 2007, 22:55-66.
54. Preacher K., Hayes A. Asymptotic and resampling strategies for assessing and comparing indirect effects in multiple mediator models. Behav. Res. Meth. 2008, 40:879-891.
55. Rutter M. Proceeding from observed correlation to causal inference: the use of natural experiments. Perspect. Psychol. Sci. 2007, 2:377-395.
56. Shonkoff J.P., Boyce W.T., McEwen B.S. Neuroscience, molecular biology, and the childhood roots of health disparities: building a new framework for health promotion and disease prevention. JAMA 2009, 301:2252-2259.
57. Slopen N., Kubzansky L.D., Koenen K.C. Childhood adversity and inflammatory and immune biomarkers associated with cardiovascular risk in youth: a systematic review. Brain Behav. Immun. 2011, 26:239-250.
58. Steptoe A., Hamer M., Chida Y. The effects of acute psychological stress on circulating inflammatory factors in humans: a review and meta-analysis. Brain Behav. Immun. 2007, 21:901-912.
59. Taylor S.E., Lehman B.J., Kiefe C.I., Seeman T.E. Relationship of early life stress and psychological functioning to adult C-reactive protein in the coronary artery risk development in young adults study. Biol. Psychiatr. 2006, 60:819-824.
60. Taylor S.E., Lerner J.S., Sage R.M., Lehman B.J., Seeman T.E. Early environment, emotions, responses to stress, and health. J. Pers. 2004, 72:1365-1393.
61. Taylor S.E., Way B.M., Seeman T.E. Early adversity and adult health outcomes. Dev. Psychopathol. 2011, 23:939-954.
62. Thomas C., Hyppönen E., Power C. Obesity and type 2 diabetes risk in midadult life: the role of childhood adversity. Pediatrics 2008, 121:e1240-e1249.
63. Timpson N.J., Lawlor D.A., Harbord R.M., Gaunt T.R., Day I.N.M., Palmer L.J., Hattersley A.T., Ebrahim S., Lowe G.D.O., Rumley A., Smith G.D. C-reactive protein and its role in metabolic syndrome: mendelian randomisation study. Lancet 2005, 366:1954-1959.
64. Tukey J.W. Exploratory Data Analysis 1977, Addison-Wesley, Reading, MA.
65. Von Korff M., Alonso J., Ormel J., Angermeyer M., Bruffaerts R., Fleiz C., de Girolamo G., Kessler R.C., Kovess-Masfety V., Posada-Villa J., Scott K.M., Uda H. Childhood psychosocial stressors and adult onset arthritis: Broad spectrum risk factors and allostatic load. Pain 2009, 143:76-83.
66. Wilcox R.R., Keselman H.J. Modern robust data analysis methods: measures of central tendency. Psychol. Methods 2003, 8:254-274.
67. Wills T.A., Sandy J.M., Yaeger A.M. Stress and smoking in adolescence: a test of directional hypotheses. Health Psychol. 2002, 21:122-130.
68. Wolf J.M., Miller G.E., Chen E. Parent psychological states predict changes in inflammatory markers in children with asthma and healthy children. Brain Behav. Immun. 2008, 22:433-441.
69. Wolke D., Waylen A., Samara M., Steer C., Goodman R., Ford T., Lamberts K. Selective drop-out in longitudinal studies and non-biased prediction of behaviour disorders. Br. J. Psychiatr. 2009, 195:249-256.
70. Wood A., Kroll L., Moore A., Harrington R. Properties of the Mood and Feelings Questionnaire in adolescent psychiatric outpatients-a research note. J. Child Psychol. Psyc. 1995, 36:327-334.