Fungal β-Glucan Activates the NLRP3 Inflammasome in Human Bronchial Epithelial Cells Through ROS Production

Inflammation

Volumn 41, Issue 1, 2018, Pages 164-173

  Huang, Yanhua ^a   Hua, Meng ^b   Cui, Xuefan ^b  

^a Qidong People s Hospital   (China)

^b THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

Author keywords

fungal glucan; human bronchial epithelial cells; NLRP3 inflammasome; ROS

Indexed keywords

CRYOPYRIN; CURDLAN; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; REACTIVE OXYGEN METABOLITE; ANTIOXIDANT; BETA GLUCAN; IL1B PROTEIN, HUMAN; NLRP3 PROTEIN, HUMAN;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; HBEC CELL LINE (BRONCHIAL); HUMAN; HUMAN CELL; MACROPHAGE; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING; AGONISTS; BRONCHUS; CELL LINE; DOSE RESPONSE; DRUG EFFECT; EPITHELIUM CELL; GENETICS; IMMUNOLOGY; METABOLISM; OXIDATIVE STRESS; SIGNAL TRANSDUCTION;

ANTIOXIDANTS; BETA-GLUCANS; BRONCHI; CASPASE 1; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; HUMANS; INTERLEUKIN-1BETA; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 85031945300     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-017-0674-6     Document Type: Article

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