Acapsular Cryptococcus neoformans activates the NLRP3 inflammasome

Microbes and Infection

Volumn 16, Issue 10, 2014, Pages 845-854

  Guo, Caiqin ^a,b   Chen, Mingkuan ^b   Fa, Zhenzong ^b,c   Lu, Ailing ^b   Fang, Wei ^c   Sun, Bing ^b   Chen, Changbin ^b   Liao, Wanqing ^c   Meng, Guangxun ^b  

^a SHANGHAI NORMAL UNIVERSITY   (China)

^b INSTITUTE PASTEUR OF SHANGHAI   (China)

^c SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Capsule; Cryptococcus neoformans; Glucuronoxylomannan; Inflammasome; NLRP3

Indexed keywords

CELL SURFACE RECEPTOR; CRYOPYRIN; INFLAMMASOME; PROTEIN AIM2; PROTEIN NLRC4; UNCLASSIFIED DRUG; CARRIER PROTEIN; INTERLEUKIN 18; INTERLEUKIN 1BETA; NLRP3 PROTEIN, HUMAN; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA;

AIDS PATIENT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPERGILLUS FUMIGATUS; CANDIDA ALBICANS; CELL INFILTRATION; CONTROLLED STUDY; CRYPTOCOCCOSIS; CRYPTOCOCCUS NEOFORMANS; HUMAN; HUMAN CELL; IMMUNOCOMPETENT CELL; IMMUNOCOMPROMISED PATIENT; IN VIVO STUDY; INFECTION CONTROL; LUNG CLEARANCE; LUNG INFECTION; MACROPHAGE; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; C57BL MOUSE; CELL LINE; DISEASE MODEL; FEMALE; GENE SILENCING; GENETICS; HOST PATHOGEN INTERACTION; IMMUNOLOGY; METABOLISM; MICROBIAL VIABILITY; MUTATION; PATHOGENICITY; PATHOLOGY;

ASPERGILLUS FUMIGATUS; CANDIDA ALBICANS; FILOBASIDIELLA NEOFORMANS; FUNGI;

ANIMALS; CARRIER PROTEINS; CELL LINE; CRYPTOCOCCOSIS; CRYPTOCOCCUS NEOFORMANS; DISEASE MODELS, ANIMAL; FEMALE; GENE SILENCING; HOST-PATHOGEN INTERACTIONS; HUMANS; INFLAMMASOMES; INTERLEUKIN-18; INTERLEUKIN-1BETA; MACROPHAGES; MICE; MICE, INBRED C57BL; MICROBIAL VIABILITY; MUTATION; REACTIVE OXYGEN SPECIES; RECEPTORS, CELL SURFACE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84926179048     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2014.08.013     Document Type: Article

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