Innate immunity but not NLRP3 inflammasome activation correlates with severity of stable COPD

Thorax

Volumn 69, Issue 6, 2014, Pages 516-524

  Di Stefano, Antonino ^a   Caramori, Gaetano ^b   Barczyk, Adam ^c   Vicari, Chiara ^a   Brun, Paola ^d   Zanini, Andrea ^a   Cappello, Francesco ^e,f,g   Garofano, Elvira ^b   Padovani, Anna ^b   Contoli, Marco ^b   Casolari, Paolo ^b   Urham, Andrew L ^h   Fan Chung, Kian ^h   Barnes, Peter J ^h   Papi, Alberto ^b   Adcock, Ian ^h   Balbi, Bruno ^a  

^a IRCCS   (Italy)

^b UNIVERSITY OF FERRARA   (Italy)

^c Katedra i Klinika Pneumonologii Slaskiego Uniwersytetu Medycznego W Katowicach   (Poland)

^d UNIVERSITY OF PADOVA   (Italy)

^e UNIVERSITY OF PALERMO   (Italy)

^f Istituto EuroMediterraneo di Scienza e Tecnologia   (Italy)

^g Department of Veterinary Medical Sciences   (Switzerland)

^h NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CRYOPYRIN; CYTOKINE; GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR; INFLAMMASOME; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 10; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 27; INTERLEUKIN 33; INTERLEUKIN 37; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; INTERLEUKIN 7; MESSENGER RNA; PEPTIDES AND PROTEINS; PROTEIN NALP7; PROTEIN SGP 130; PROTEIN ST2; STAT1 PROTEIN; THYMIC STROMAL LYMPHOPOIETIN; UNCLASSIFIED DRUG;

AGED; ARTICLE; BRONCHUS BIOPSY; BRONCHUS MUCOSA; CELL COUNT; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CORRELATIONAL STUDY; DISEASE COURSE; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INFLAMMATORY CELL; INNATE IMMUNITY; LUNG LAVAGE; MALE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SMOKING; SUBMUCOSA;

COPD PATHOLOGY; INNATE IMMUNITY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AGED; BRONCHI; BRONCHOALVEOLAR LAVAGE FLUID; CARRIER PROTEINS; CASE-CONTROL STUDIES; CYTOKINE RECEPTOR GP130; CYTOKINES; FEMALE; HMGB1 PROTEIN; HUMANS; IMMUNITY, INNATE; INFLAMMASOMES; INTERFERON-GAMMA; INTERLEUKINS; MALE; MIDDLE AGED; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RECEPTORS, CELL SURFACE; RESPIRATORY MUCOSA; SMOKING; STAT1 TRANSCRIPTION FACTOR;

EID: 84901240710     PISSN: 00406376     EISSN: 14683296     Source Type: Journal    
DOI: 10.1136/thoraxjnl-2012-203062     Document Type: Article

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