A Highly Pathogenic Avian H7N9 Influenza Virus Isolated from A Human Is Lethal in Some Ferrets Infected via Respiratory Droplets

Cell Host and Microbe

Volumn 22, Issue 5, 2017, Pages 615-626.e8

  Imai, Masaki ^a   Watanabe, Tokiko ^a   Kiso, Maki ^a   Nakajima, Noriko ^b   Yamayoshi, Seiya ^a   Iwatsuki Horimoto, Kiyoko ^a   Hatta, Masato ^c   Yamada, Shinya ^a   Ito, Mutsumi ^a   Sakai Tagawa, Yuko ^a   Shirakura, Masayuki ^b   Takashita, Emi ^b   Fujisaki, Seiichiro ^b   McBride, Ryan ^d   Thompson, Andrew J ^d   Takahashi, Kenta ^b   Maemura, Tadashi ^a   Mitake, Hiromichi ^a   Chiba, Shiho ^c   Zhong, Gongxun ^c   Fan, Shufang ^c   Oishi, Kohei ^a   Yasuhara, Atsuhiro ^a   Takada, Kosuke ^a   Nakao, Tomomi ^a   Fukuyama, Satoshi ^a   Yamashita, Makoto ^a   Lopes, Tiago J S ^a,c   Neumann, Gabriele ^c   Odagiri, Takato ^b   Watanabe, Shinji ^b   Shu, Yuelong ^e   Paulson, James C ^d   Hasegawa, Hideki ^b   Kawaoka, Yoshihiro ^a,c   more..

^a UNIVERSITY OF TOKYO   (Japan)

^b NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

^e CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

Author keywords

antiviral sensitivity; ferrets; highly pathogenic avian influenza H7N9 viruses; mice; nonhuman primates; pathogenicity; receptor binding specificity; replication capacity; transmissibility

Indexed keywords

FAVIPIRAVIR; LANINAMIVIR; OSELTAMIVIR; PERAMIVIR; ZANAMIVIR; ANTIVIRUS AGENT; ENZYME INHIBITOR; SIALIDASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIVIRAL RESISTANCE; ANTIVIRAL SUSCEPTIBILITY; ARTICLE; BRONCHUS EPITHELIUM; COMPARATIVE STUDY; CONTROLLED STUDY; DNA SEQUENCE; ENZYME INHIBITION; FEMALE; HIGHLY PATHOGENIC AVIAN INFLUENZA; HIGHLY PATHOGENIC AVIAN INFLUENZA VIRUS; HUMAN; HUMAN CELL; INFLUENZA A (H7N9); INFLUENZA A VIRUS (H7N9); LOW PATHOGENIC AVIAN INFLUENZA; LOW PATHOGENIC AVIAN INFLUENZA VIRUS; MACACA FASCICULARIS; MALE; MOUSE; MUSTELA PUTORIUS FURO; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; VIROGENESIS; VIRUS ATTENUATION; VIRUS ISOLATION; VIRUS REPLICATION; VIRUS TRANSMISSION; VIRUS VIRULENCE; ANIMAL; AVIAN INFLUENZA; BRAIN; CELL LINE; CHICKEN; CONJUNCTIVA; DISEASE MODEL; DRUG EFFECT; ISOLATION AND PURIFICATION; LUNG; MACACA; ORTHOMYXOVIRUS INFECTION; PATHOGENICITY; PATHOLOGY; RESPIRATORY TRACT INFECTION; TRANSMISSION; VIROLOGY;

ANIMALS; ANTIVIRAL AGENTS; BRAIN; CELL LINE; CHICKENS; CONJUNCTIVA; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; FERRETS; HUMANS; INFLUENZA A VIRUS, H7N9 SUBTYPE; INFLUENZA IN BIRDS; LUNG; MACACA; MICE; NEURAMINIDASE; ORTHOMYXOVIRIDAE INFECTIONS; RESPIRATORY TRACT INFECTIONS; VIRUS REPLICATION;

EID: 85031791832     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2017.09.008     Document Type: Article

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