A Gut Microbial Mimic that Hijacks Diabetogenic Autoreactivity to Suppress Colitis

Cell

Volumn 171, Issue 3, 2017, Pages 655-667.e17

  Hebbandi Nanjundappa, Roopa ^a,e   Ronchi, Francesca ^b   Wang, Jinguo ^a,e   Clemente Casares, Xavier ^a,e   Yamanouchi, Jun ^a,e   Sokke Umeshappa, Channakeshava ^a,e   Yang, Yang ^a,e   Blanco, Jesús ^c,d   Bassolas Molina, Helena ^c   Salas, Azucena ^c   Khan, Hamza ^e   Slattery, Robyn M ^f   Wyss, Madeleine ^b   Mooser, Catherine ^b   Macpherson, Andrew J ^b   Sycuro, Laura K ^e   Serra, Pau ^c   McKay, Derek M ^a   McCoy, Kathy D ^b   Santamaria, Pere ^a,c,e  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF BERN   (Switzerland)

^c INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

^d HOSPITAL CLÍNIC   (Spain)

^e UNIVERSITY OF CALGARY   (Canada)

^f MONASH UNIVERSITY   (Australia)

Author keywords

Bacteroides Integrase; Cytotoxic T cells; Germ free mice; Inflammatory bowel disease; Islet specific glucose 6 phosphatase catalytic subunit related protein (IGRP); Molecular mimicry

Indexed keywords

BETA7 INTEGRIN; GLUCOSE 6 PHOSPHATASE; ISLET SPECIFIC GLUCOSE 6 PHOSPHATASE CATALYTIC SUBUNIT RELATED PROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PERFORIN; UNCLASSIFIED DRUG; AUTOANTIGEN; G6PC2 PROTEIN, HUMAN; G6PC2 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTEROIDES VULGATUS; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; DEXTRAN SULFATE SODIUM-INDUCED COLITIS; DIABETOGENESIS; FEMALE; HOMEOSTASIS; HUMAN; HUMAN CELL; INTESTINE FLORA; LIMIT OF QUANTITATION; MALE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN TARGETING; ADULT; ANIMAL; BACTEROIDES; BAGG ALBINO MOUSE; CLASSIFICATION; COLITIS; ENZYMOLOGY; GENETICS; IMMUNOLOGY; LYMPHOID TISSUE; MICROBIOLOGY; MIDDLE AGED; MOLECULAR MIMICRY; NONOBESE DIABETIC MOUSE; T LYMPHOCYTE;

ADULT; ANIMALS; AUTOANTIGENS; BACTEROIDES; COLITIS; FEMALE; GASTROINTESTINAL MICROBIOME; GLUCOSE-6-PHOSPHATASE; HUMANS; LYMPHOID TISSUE; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED NOD; MIDDLE AGED; MOLECULAR MIMICRY; T-LYMPHOCYTES;

EID: 85031783568     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2017.09.022     Document Type: Article

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