Caprylic and polygalacturonic acid combinations for eradication of microbial organisms embedded in biofilm

Frontiers in Microbiology

Volumn 8, Issue OCT, 2017, Pages

  Rosenblatt, Joel ^a   Reitzel, Ruth A ^a   Vargas Cruz, Nylev ^a   Chaftari, Anne Marie ^a   Hachem, Ray ^a   Raad, Issam ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Biofilm eradication; Caprylic acid; Infection; Polygalacturonic acid; Synergy

Indexed keywords

OCTANOIC ACID; POLYGALACTURONIC ACID;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ARTICLE; BIOFILM; CANDIDA ALBICANS; CELL METABOLISM; COLONY FORMING UNIT; CONTROLLED STUDY; ESCHERICHIA COLI; FIBROBLAST CULTURE; GROWTH INHIBITION; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; MOUSE; NONHUMAN; PATHOGEN CLEARANCE; PSEUDOMONAS AERUGINOSA; RESAZURIN ASSAY; SALMONELLA ENTERICA SEROVAR ENTERITIDIS; TRYPAN BLUE ASSAY;

EID: 85031764194     PISSN: None     EISSN: 1664302X     Source Type: Journal    
DOI: 10.3389/fmicb.2017.01999     Document Type: Article

References (39)

1. Akhtar, M., Dickinson, E., Mazoyer, J., and Langendorff, V. (2002). Emulsion stabilizing properties of depolymerized pectin. Food Hydrocoll. 16, 249-256. doi: 10.1016/S0268-005X(01)00095-9
2. Centers for Disease Control and Prevention (2013). Antibiotic Resistance Threats in the United States, 2013. Atlanta, GA: Centers for Disease Control and Prevention.
3. Christen, V., Faltermann, S., Brun, N. R., Kunz, P. Y., and Fent, K. (2017). Cytotoxicity and molecular effects of biocidal disinfectants (quaternary ammonia, glutaraldehyde, poly(hexamethylene biguanide) hydrochloride PHMB) and their mixtures in vitro and in zebrafish eleuthero-embryos. Sci. Total Environ. 586, 1204-1218. doi: 10.1016/j.scitotenv.2017.02.114
4. CLSI (2015). M07-A10 - Methods for Dilution Antimicrobial Susceptibility Tested for Bacteria that Grow Aerobically; Approved Standard, 10th Edn. Wayne, PA: CLSI.
5. Costerton, J. W., Stewart, P. S., and Greenberg, E. P. (1999). Bacterial biofilms: a common cause of persistent infections. Science 284, 1318-1322. doi: 10.1126/science.284.5418.1318
6. CRC (2004-2005). Handbook of Chemistry and Physics. New York, NY: CRC Press.
7. de Gomes, P. S., Figueiral, M. H., Fernandes, M. H., and Scully, C. (2011). Cytotoxicity of denture adhesives. Clin. Oral Investig. 15, 885-893. doi: 10.1007/s00784-010-0464-0
8. Donlan, R. M., and Costerton, J. W. (2002). Biofilms: survival mechanisms of clinically relevant microorganisms. Clin. Microbiol. Rev. 15, 167-193. doi: 10.1128/CMR.15.2.167-193.2002
9. Espitia, P., Du, W., Avena-Bustillos, R., Soares, N., and McHugh, T. (2014). Edible films from pectin: physical-mechanical and antimicrobial properties - A review. Food Hydrocoll. 35, 287-296. doi: 10.1016/j.foodhyd.2013.06.005
10. Evans, D. F., Pye, G., Bramley, R., Clark, A. G., Dyson, T. J., and Hardcastle, J. D. (1988). Measurement of gastrointestinal pH profiles in normal ambulant human subjects. Gut 29, 1035-1041. doi: 10.1136/gut.29.8.1035
11. Hirabara, S. M., Silveira, L. R., Alberici, L. C., Leandro, C. V., Lambertucci, R. H., Polimeno, G. C., et al. (2006). Acute effect of fatty acids on metabolism and mitochondrial coupling in skeletal muscle. Biochim. Biophys. Acta 1757, 57-66. doi: 10.1016/j.bbabio.2005.11.007
12. Hoerr, C. W., Sedgwick, R. S., and Ralston, A. W. (1946). The solubilities of the normal saturated fatty acids. J. Org. Chem. 11, 603-609. doi: 10.1021/jo01175a025
13. James, G. A., Swogger, E., Wolcott, R., Pulcini, E., Secor, P., Sestrich, J., et al. (2008). Biofilms in chronic wounds. Wound Repair. Regen. 16, 37-44. doi: 10.1111/j.1524-475X.2007.00321.x
14. Jensen, R. G., Ferris, A. M., Lammi-Keefe, C. J., and Henderson, R. A. (1990). Lipids of bovine and human milks: a comparison. J. Dairy Sci. 73, 223-240. doi: 10.3168/jds.S0022-0302(90)78666-3
15. Kim, B. S., Ott, V., Boecker, A. H., Stromps, J. P., Paul, N. E., Alharbi, Z., et al. (2017). The effect of antiseptics on adipose-derived stem cells. Plast Reconstr. Surg. 139, 625-637. doi: 10.1097/prs.0000000000003125
16. Kim, S. A., and Rhee, M. S. (2016). Antibacterial activity of caprylic acid for potential application as an active antiseptic ingredient in consumer antiseptics. Int. J. Antimicrob. Agents 48, 765-767. doi: 10.1016/j.ijantimicag.2016.09.002
17. Kuhn, D. M., George, T., Chandra, J., Mukherjee, P. K., and Ghannoum, M. A. (2002). Antifungal susceptibility of Candida biofilms: unique efficacy of amphotericin B lipid formulations and echinocandins. Antimicrob. Agents Chemother. 46, 1773-1780. doi: 10.1128/AAC.46.6.1773-1780.2002
18. Lambers, H., Piessens, S., Bloem, A., Pronk, H., and Finkel, P. (2006). Natural skin surface pH is on average below 5, which is beneficial for its resident flora. Int. J. Cosmet. Sci. 28, 359-370. doi: 10.1111/j.1467-2494.2006.00344.x
19. Lang, W. R. (1955). Vaginal acidity and pH; a review. Obstet. Gynecol. Surv. 10, 546-560. doi: 10.1097/00006254-195508000-00009
20. Lee, D. S., Sinno, S., and Khachemoune, A. (2011). Honey and wound healing: an overview. Am. J. Clin. Dermatol. 12, 181-190. doi: 10.2165/11538930-000000000-00000
21. Liang, R.-H., Wang, L.-H., Chen, J., Liu, W., and Liu, C.-M. (2015). Alkylated pectin: synthesis, characterization, viscosity and emulsifying properties. Food Hydrocoll. 50, 65-73. doi: 10.1016/j.foodhyd.2015.04.007
22. Magill, S. S., Edwards, J. R., Bamberg, W., Beldavs, Z. G., Dumyati, G., Kainer, M. A., et al. (2014). Multistate point-prevalence survey of health care-associated infections. N. Engl. J. Med. 370, 1198-1208. doi: 10.1056/NEJMoa1306801
23. Marina, A. M., Che Man, Y. B., Nazimah, S. A. H., and Amin, I. (2009). Chemical properties of virgin coconut oil. J. Am. Oil Chem. Soc. 86, 301-307. doi: 10.1007/s11746-009-1351-1
24. Miquel, S., Lagrafeuille, R., Souweine, B., and Forestier, C. (2016). Anti-biofilm activity as a health issue. Front. Microbiol. 7:592. doi: 10.3389/fmicb.2016.00592
25. Munarin, F., Tanzi, M. C., and Petrini, P. (2012). Advances in biomedical applications of pectin gels. Int. J. Biol. Macromol. 51, 681-689. doi: 10.1016/j.ijbiomac.2012.07.002
26. National Center for Emerging and Zoonotic Infectious Diseases, and Division of Foodborne, Waterborne, and Environmental Diseases (2016). Estimates of Foodborne Illness in the United States. Atlanta, GA: Centers For Disease Control and Prevention.
27. Nobile, C. J., and Johnson, A. D. (2015). Candida albicans biofilms and human disease. Annu. Rev. Microbiol. 69, 71-92. doi: 10.1146/annurev-micro-091014-104330
28. O'Brien, J., Wilson, I., Orton, T., and Pognan, F. (2000). Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity. Eur. J. Biochem. 267, 5421-5426. doi: 10.1046/j.1432-1327.2000.01606.x
29. Pieper, B. (2009). Honey-based dressings and wound care: an option for care in the United States. J. Wound Ostomy Continence Nurs. 36, 60-66. doi: 10.1097/01.WON.0000345177.58740.7d
30. Pieper, B., and Caliri, M. H. (2003). Nontraditional wound care: a review of the evidence for the use of sugar, papaya/papain, and fatty acids. J. Wound Ostomy Continence Nurs. 30, 175-183. doi: 10.1067/mjw.2003.131
31. Pohl, C., Kock, J., and Thibane, V. (2011). "Antifungal free fatty acids: a Review," in Science against Microbial Pathogens: Communicating Current Research and Technological Advances, ed. A. Mendez-Vilas (Badajoz: Formatex), 61-71.
32. Rayyan, M., Devlieger, H., Jochum, F., and Allegaert, K. (2012). Short-term use of parenteral nutrition with a lipid emulsion containing a mixture of soybean oil, olive oil, medium-chain triglycerides, and fish oil: a randomized double-blind study in preterm infants. JPEN J. Parenter. Enteral Nutr. 36(Suppl. 1), 81S-94S. doi: 10.1177/0148607111424411
33. Schreml, S., Szeimies, R. M., Karrer, S., Heinlin, J., Landthaler, M., and Babilas, P. (2010). The impact of the pH value on skin integrity and cutaneous wound healing. J. Eur. Acad. Dermatol. Venereol. 24, 373-378. doi: 10.1111/j.1468-3083.2009.03413.x
34. Sriamornsak, P. (2013). Chemistry of pectin and its pharmaceutical uses: a review. Silpakorn Univ. J. 3, 206-228.
35. Srivastava, P., and Durgaprasad, S. (2008). Burn wound healing property of Cocos nucifera: an appraisal. Indian J. Pharmacol. 40, 144-146. doi: 10.4103/0253-7613.43159
36. Strober, W. (2015). Trypan blue exclusion test of cell viability. Curr. Protoc. Immunol. 21, A.3B.1-A.3B.2. doi: 10.1002/0471142735.ima03bs111
37. Van Acker, H., Van Dijck, P., and Coenye, T. (2014). Molecular mechanisms of antimicrobial tolerance and resistance in bacterial and fungal biofilms. Trends Microbiol. 22, 326-333. doi: 10.1016/j.tim.2014.02.001
38. Van Houdt, R., and Michiels, C. W. (2010). Biofilm formation and the food industry, a focus on the bacterial outer surface. J. Appl. Microbiol. 109, 1117-1131. doi: 10.1111/j.1365-2672.2010.04756.x
39. Wanten, G. J., and Calder, P. C. (2007). Immune modulation by parenteral lipid emulsions. Am. J. Clin. Nutr. 85, 1171-1184.