Nontraditional wound care: A review of the evidence for the use of sugar, papaya/papain, and fatty acids

Journal of Wound, Ostomy and Continence Nursing

Volumn 30, Issue 4, 2003, Pages 175-183

  Pieper, Barbara ^a   Larcher Caliri, Maria Helena ^b  

^a WAYNE STATE UNIVERSITY   (United States)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID DERIVATIVE; PAPAIN;

BRAZIL; CLINICAL PROTOCOL; DEVELOPED COUNTRY; ECONOMICS; EVIDENCE BASED MEDICINE; HUMAN; MEDICAL RESEARCH; NURSE; PAPAYA; REVIEW; TRADITIONAL MEDICINE; WOUND CARE;

EID: 0041621824     PISSN: 10715754     EISSN: None     Source Type: Journal    
DOI: 10.1067/mjw.2003.131     Document Type: Article

References (41)

1. Instituto Brasileiro de Geografia e Estatistica, IBGE, Censo, 2000, (2002 July 20) [online]. Available from: URL: http://www.sidra.ibge.gov.br/bda/pesquisas/cdru/
2. Knutson RA, Merbitz LA, Creekmore MA, Snipes HG. Use of sugar and povidone-iodine to enhance wound healing: Five years' experience. South Med J 1981;74:1329-35.
3. Dawson JS. The role of sugar in wound healing. Ann R Coll Surg Engl 1996;78(2 Suppl):82-5.
4. Haddad MC, Vannuchi MTO, Chenso MZB, Hauly COM. O uso de acucar nas feridas infectadas. Rev Bras Enf 1983;36:152-63.
5. Fundacao de Amparo a Pesquisa do Estado de Sao Paulo - FAPESP (2002 July 20) [online]. Available from: URL: http://www.fapesp.br/genoma393.htm
6. Kilic A. Healing of diabetic ulcers with granulated sugar. Plast Reconstr Surg 2001;108:585.
7. Glass LM. We use granulated sugar in the treatment of decubitus ulcers. Geriatr Nurs 1966;2:44.
8. Chirife J, Scarmato G, Herszage L. Scientific basis for use of granulated sugar in treatment of infected wounds. Lancet 1982;1:560-1.
9. Valls LT, Altisen MT, Poblador RP, Alvarez AC, Biosca RG. Sugar paste for treatment of decubital ulcers. J Pharm Technology 1996;12:289-90.
10. Archer HG, Barnett S, Irving S, Middleton KR, Seal DV. A controlled model of moist wound healing: comparison between semi-permeable film, antiseptics and sugar paste. J Exp Pathol 1990;71:155-70.
11. Trouillet JL, Chastre J, Fagon JY, Pierre J, Domart Y, Gibert C. Use of granulated sugar in treatment of open mediastinitis after cardiac surgery. Lancet 1985;2(8448):180-4.
12. Szerafin T, Vaszily M, Peterffy A. Granulated sugar treatment of severe mediastinitis after open-heart surgery. Scand J Thor Cardiovasc Surg 1991;25:77-80.
13. De Feo M, Gregorio R, Renzulli A, Ismeno G, Romano GP, Cotrufo M. Treatment of recurrent postoperative mediastinitis with granulated sugar. J Cardiovasc Surg 2000;41:715-9.
14. Debure A, Gachot B, Lacour B, Kreis H. Acute renal failure after use of granulated sugar in deep infected wound. Lancet 1987;1:1034-5.
15. Beadling L. A bag full of sugar. Surgeons find that ordinary table sugar is a sweet adjunct to conventional therapy of deep wound healing. Todays Surg Nurse 1997;19:28-30.
16. Toba K, Sudoh N, Nagano K, Eto M, Mizuno Y, Nakagawa H, et al. Randomized prospective trial of gentian violet with dibutyryl cAMP and povidone-iodine with sugar as treatment for pressure sores infected with methicillin-resistant Staphylococcus aureus in elderly patients. Jpn J Geriatr 1997;34:577-82.
17. Seal DV, Middleton K. Healing of cavity wounds with sugar. Lancet 1991;338:571-2.
18. Glass LM. We use granulated sugar in the treatment of decubitus ulcers. Geriatr Nurs 1966;2:44.
19. Grauwin MY, Cartel JL, Lepers JP. How does one treat the osteitis and osteoarthritis of the extremities in older leprosy patients using granulated table sugar? Acta Leprol 1999;11:147-52.
20. Wiseman LA. Sugar as an aid to wound healing and the treatment of ulcers of leprosy. Lepr Rev 1989;60:67-8.
21. Haddad MCL, Bruschi LC, Martins EAP. Influencia do acucar no processo de cicatrizacao de incisoes cirurgicas infectadas. Rev Latino-am Enfermagem-Ribeirao Preto 2000;8:57-65.
22. Klasen HJ. A review on the nonoperative removal of necrotic tissue from burn wounds. Burns 2000;26:207-22.
23. Hewitt H, Wint Y, Talabere L, Lopez S, Bailey E, Parshad O, et al. The use of payapa on pressure ulcers. Am J Nurs 2002;102;73-7.
24. Monetta L. Uso da papaina nos curativos feitos pela enfermagem. Rev Bras Enfer 1987;40:66-73.
25. Starley IF, Mohammed P, Schneider G, Bickler SW. The treatment of paediatric burns using topical papaya. Burns 1999;25:636-9.
26. Monetta L. Analise evolutiva do processo de cicatrizacao em ulceras diabeticas, de pressao e venosas com uso de papaina. Dissertacao (Mestrado), Escola de Enfermagem, Universidade de Sao Paulo, 1998.
27. Otuka ES, Pedrazzani ES, Pioto MP. Uso da papaina na ulcera plantar. Rev Bras Enfermagem 1996;49:207-14.
28. Rogenski NMB, Guedes ML, Baptista CMC, Costa LDF. Uso de papaina em infeccoes de visceras. Rev Bras Enfermagem 1995;48:140-3.
29. Karski J, Wolski T, Skublewski K, Wolski J, Karski M. The use of vegetable proteolytic enzymes in the treatment of surgical diseases. Ann Univ Mariae Curie Sklodowska 1994;49:125-8.
30. Mekkes JR, Le Poole IC, Das PK, Kammeyer A, Westerhof W. In vitro tissue-digesting properties of krill enzymes compared with Fibrinolysin/DNAse, papain, and placebo. Int J Biochem Cell Biol 1997;29:703-6.
31. Declair V. The usefulness of topical application of essential fatty acids (EFA) to prevent pressure ulcers. Ostomy Wound Manage 1997;43:48-54.
32. Candido LC. Treatment of surgical wound dehiscence. Dermatol Nurs 2002;14:177-81.
33. Jelenko C III, Wheller ML, Anderson AP, Callaway D, Scott RA. Studies in burns. XIII. Effects of a topical lipid on burned subjects and their wounds. Am Surg 1975;41:466-82.
34. Jelenko C III, Wheller ML, Anderson AP, Callaway D, McKinley JC. Studies in burns. XIV. Healing in burn wounds treated with ethyl linoleate alone or in combination with selected topical antibacterial agents. Ann Surg 1975;182:562-6.
35. Jelenko C III, McKinley JC. Studies in burns. XV. Use of a topical lipid in treating human burns. Am Surg 1976;42:838-48.
36. Peter RU, Gottlober P. Management of cutaneous radiation injuries: diagnostic and therapeutic principles of the cutaneous radiation syndrome. Mil Med 2002;167(2 Suppl):110-2.
37. Driever MJ. Are evidenced-based practice and best practice the same? West J Nurs Res 2002;24:591-7.
38. Doughty D. Show me the data. J Wound Ostomy Continence Nurs 2000;27:199-200.
39. Amarsi Y. Evidenced-based nursing: perspective from Pakistan. Reflections Nurs Leadersh 2002;28:28-9,46.
40. Aroian KJ. A model of psychological adaptation to migration and resettlement. Nurs Res 1990;39:5-10.
41. Eisenberg DM, Davis RB, Ettner SL, Appel S, Wilkey S, VanRompay D, et al. Trends in alternative medicine use in the United States, 1990-1997. JAMA 1998;280:1569-75.