Drosophila Histone Demethylase KDM4A Has Enzymatic and Non-enzymatic Roles in Controlling Heterochromatin Integrity

Developmental Cell

Volumn 42, Issue 2, 2017, Pages 156-169.e5

  Colmenares, Serafin U ^a   Swenson, Joel M ^a,b   Langley, Sasha A ^a   Kennedy, Cameron ^a   Costes, Sylvain V ^a   Karpen, Gary H ^a,b  

^a LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^b University of California Berkeley   (United States)

Author keywords

dKDM4A; DNA repair; Drosophila; H3K36me3; H3K56me3; heterochromatin; histone demethylase; HP1a; position effect variegation; H2Av

Indexed keywords

HETEROCHROMATIN PROTEIN 1; HETEROCHROMATIN PROTEIN 1A; HISTONE DEMETHYLASE; HISTONE DEMETHYLASE KDM4A; REPETITIVE DNA; UNCLASSIFIED DRUG; DROSOPHILA PROTEIN; HETEROCHROMATIN; HISTONE; KDM4A PROTEIN, DROSOPHILA; LYSINE;

ARTICLE; CATALYSIS; CELL CYCLE; CONTROLLED STUDY; DEMETHYLATION; DNA DAMAGE; DNA REPAIR; DOUBLE STRANDED DNA BREAK; DROSOPHILA; ENZYME ACTIVITY; ENZYME LOCALIZATION; EUCHROMATIN; GENE MUTATION; GENE SILENCING; HETEROCHROMATIN; NONHUMAN; POSITION EFFECT VARIEGATION; PRIORITY JOURNAL; PROTEIN FUNCTION; SURVIVAL; TRANSCRIPTION REGULATION; ANIMAL; BIOCATALYSIS; CELL CYCLE CHECKPOINT; CHEMISTRY; CYTOLOGY; DROSOPHILA MELANOGASTER; ENZYMOLOGY; FERTILITY; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; METHYLATION; MUTATION; PROTEIN DOMAIN;

ANIMALS; BIOCATALYSIS; CELL CYCLE; CELL CYCLE CHECKPOINTS; CHROMOSOMAL POSITION EFFECTS; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FERTILITY; GENE EXPRESSION REGULATION; GENE SILENCING; HETEROCHROMATIN; HISTONE DEMETHYLASES; HISTONES; LYSINE; METHYLATION; MUTATION; PROTEIN DOMAINS; TRANSCRIPTION, GENETIC;

EID: 85030430788     PISSN: 15345807     EISSN: 18781551     Source Type: Journal    
DOI: 10.1016/j.devcel.2017.06.014     Document Type: Article

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