Nonencapsidated 5' copy-back defective interfering genomes produced by recombinant measles viruses are recognized by RIG-I and LGP2 but not MDA5

Journal of Virology

Volumn 91, Issue 20, 2017, Pages

  Mura, Marie ^a,b   Combredet, Chantal ^a   Najburg, Valérie ^a   David, Raul Y Sanchez ^a   Tangy, Frédéric ^a   Komarova, Anastassia V ^a  

^a INSTITUT PASTEUR   (France)

^b INSTITUT DE RECHERCHE BIOMÉDICALE DES ARMÉES   (France)

Author keywords

Defective interfering RNA; Innate immunity; Measles virus; RIG I like receptors; Type I interferon

Indexed keywords

5' COPY BACK DEFECTIVE INTERFERING GENOME RNA; BETA INTERFERON; COMPLEMENTARY DNA; INTERFERON INDUCED HELICASE C DOMAIN CONTAINING PROTEIN 1; LGP2 RECEPTOR; MESSENGER RNA; NUCLEOCAPSID PROTEIN; PATHOGEN ASSOCIATED MOLECULAR PATTERN; RECEPTOR; RETINOIC ACID INDUCIBLE PROTEIN I; RIBONUCLEOPROTEIN; UNCLASSIFIED DRUG; DHX58 PROTEIN, HUMAN; IFIH1 PROTEIN, HUMAN; MEASLES VACCINE; RARRES3 PROTEIN, HUMAN; RETINOIC ACID RECEPTOR; RNA HELICASE; VIRUS RNA;

A-549 CELL LINE; ADAPTIVE IMMUNITY; ANIMAL CELL; ANTIGEN EXPRESSION; ANTIGEN RECOGNITION; ARTICLE; BINDING AFFINITY; BINDING SITE; BREAKPOINT SITE; COMPARATIVE STUDY; CONTROLLED STUDY; DNA MODIFICATION; EMBRYO; ENCAPSIDATION; GENE AMPLIFICATION; GENETIC TRANSFECTION; HEK293T CELL LINE; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; INDEL MUTATION; INNATE IMMUNITY; INTRACELLULAR SIGNALING; MEASLES VIRUS; MOLECULAR CLONING; MOLECULAR DYNAMICS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN RNA BINDING; REINITIATION SITE; RNA ANALYSIS; RNA SEQUENCE; RNA STRUCTURE; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; VERO CELL LINE; VIRUS GENOME; VIRUS RECOMBINANT; VIRUS REPLICATION; CELL LINE; GENETICS; IMMUNOLOGY; MEASLES; METABOLISM; PATHOGENICITY; SIGNAL TRANSDUCTION; VIROLOGY; VIRUS NUCLEOCAPSID;

CELL LINE; GENOME, VIRAL; HUMANS; IMMUNITY, INNATE; INTERFERON-BETA; INTERFERON-INDUCED HELICASE, IFIH1; MEASLES; MEASLES VACCINE; MEASLES VIRUS; NUCLEOCAPSID; RECEPTORS, RETINOIC ACID; RNA HELICASES; RNA, VIRAL; SIGNAL TRANSDUCTION;

EID: 85030106047     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00643-17     Document Type: Article

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