Gut microbial metabolite TMAO contributes to renal dysfunction in a mouse model of diet-induced obesity

Biochemical and Biophysical Research Communications

Volumn 493, Issue 2, 2017, Pages 964-970

  Sun, Guangping ^a   Yin, Zhongmin ^b   Liu, Naiquan ^a   Bian, Xiaohui ^a   Yu, Rui ^a   Su, Xiaoxiao ^a   Zhang, Beiru ^a   Wang, Yanqiu ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

^b The 463 Hospital of Chinese PLA   (China)

Author keywords

High fat diet; Inflammation; Oxidative stress; Renal injury; Trimethylamine N Oxide

Indexed keywords

CHOLESTEROL; CYSTATIN C; INSULIN; INTERLEUKIN 1BETA; KIDNEY INJURY MOLECULE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; SMAD3 PROTEIN; TRIACYLGLYCEROL; TRIMETHYLAMINE OXIDE; TUMOR NECROSIS FACTOR; METHYLAMINE; TRIMETHYLOXAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; BLOOD PRESSURE; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIET INDUCED OBESITY; INSULIN BLOOD LEVEL; KIDNEY FAILURE; KIDNEY FIBROSIS; LIPID DIET; MALE; METABOLIC PARAMETERS; MOUSE; NEPHRITIS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TRIACYLGLYCEROL BLOOD LEVEL; ADVERSE EFFECTS; ANIMAL; BLOOD; C57BL MOUSE; DISEASE MODEL; HEMODYNAMICS; INFLAMMATION; INTESTINE FLORA; KIDNEY; KIDNEY DISEASES; METABOLISM; MICROBIOLOGY; OBESITY; PATHOLOGY;

ANIMALS; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; GASTROINTESTINAL MICROBIOME; HEMODYNAMICS; INFLAMMATION; KIDNEY; KIDNEY DISEASES; MALE; METHYLAMINES; MICE; MICE, INBRED C57BL; OBESITY; OXIDATIVE STRESS;

EID: 85029905510     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2017.09.108     Document Type: Article

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