Induction of autophagy by spermidine is neuroprotective via inhibition of caspase 3-mediated Beclin 1 cleavage

Cell Death and Disease

Volumn 8, Issue 4, 2017, Pages

  Yang, Yi ^a,b   Chen, Sicong ^b,c   Zhang, Yuqing ^a   Lin, Xiaoxia ^a   Song, Yiyin ^a   Xue, Zhaoliang ^d   Qian, Haoran ^e   Wang, Shanshan ^a   Wan, Guihua ^a   Zheng, Xiaoxiang ^b   Zhang, Lihui ^a  

^a HANGZHOU NORMAL UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

^c THE SECOND AFFILIATED HOSPITAL OF ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^d ZHEJIANG UNIVERSITY   (China)

^e ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BECLIN 1; CASPASE 3; NEUROPROTECTIVE AGENT; SPERMIDINE; STAUROSPORINE; BECN1 PROTEIN, RAT; CASP3 PROTEIN, RAT;

ANIMAL MODEL; APOPTOSIS; ARTICLE; AUTOLYSOSOME; AUTOPHAGOSOME; AUTOPHAGY; BRAIN CELL; BRAIN ISCHEMIA; CELL DAMAGE; CELL DEATH; CONTROLLED STUDY; ENZYME INHIBITION; GENE MUTATION; HIPPOCAMPUS; IN VITRO STUDY; IN VIVO STUDY; MALE; MITOCHONDRIAL MEMBRANE; MOUSE; NERVE CELL LESION; NEUROPROTECTION; NONHUMAN; PC12 CELL LINE; PRIORITY JOURNAL; PROTEIN CLEAVAGE; RAT; ANIMAL; BRAIN CORTEX; DRUG EFFECTS; GENETICS; METABOLISM; NERVE CELL; PATHOLOGY; PROTEIN DEGRADATION; REPERFUSION INJURY;

ANIMALS; AUTOPHAGY; BECLIN-1; CASPASE 3; CEREBRAL CORTEX; HIPPOCAMPUS; NEURONS; NEUROPROTECTIVE AGENTS; PC12 CELLS; PROTEOLYSIS; RATS; REPERFUSION INJURY; SPERMIDINE;

EID: 85029386115     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2017.161     Document Type: Article

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