Real-time imaging of perivascular transport of nanoparticles during convection-enhanced delivery in the Rat cortex

Annals of Biomedical Engineering

Volumn 40, Issue 2, 2012, Pages 292-303

  Foley, Conor P ^a,c   Nishimura, Nozomi ^a   Neeves, Keith B ^b   Schaffer, Chris B ^a   Olbricht, William L ^a  

^a Cornell University   (United States)

^b Department of Geology and Geological Engineering   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Microfluidics; Neural drug delivery; Two photon microscopy

Indexed keywords

BLOOD-BRAIN BARRIER; BRAIN PARENCHYMA; CONVECTION-ENHANCED DELIVERY; CONVECTIVE TRANSPORT; EXTRACELLULAR MATRICES; FLUORESCENT NANOPARTICLES; HIGH MOLECULAR WEIGHT; HIGH PERMEABILITY; MICROFLUIDIC PROBES; NEURAL TISSUE; REALTIME IMAGING; TARGET TISSUES; TWO-PHOTON EXCITED FLUORESCENCE MICROSCOPIES; TWO-PHOTON MICROSCOPY; VASCULAR TOPOLOGY; VIRAL VECTORS;

BLOOD VESSELS; DRUG DELIVERY; FLUORESCENCE MICROSCOPY; LIPOSOMES; MICROFLUIDICS; NANOPARTICLES; PHOSPHOLIPIDS; PHOTONICS; RATS; VECTOR SPACES;

TISSUE;

BOVINE SERUM ALBUMIN; FLUORESCENT DYE; NANOPARTICLE; POLYSTYRENE DERIVATIVE;

ANIMAL; ARTICLE; BRAIN CORTEX; EXTRACELLULAR MATRIX; MALE; METABOLISM; MICROFLUIDIC ANALYSIS; MULTIPHOTON MICROSCOPY; PARTICLE SIZE; RAT; SPRAGUE DAWLEY RAT; THERMODYNAMICS; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; BIOLOGICAL TRANSPORT; CEREBRAL CORTEX; CONVECTION; EXTRACELLULAR MATRIX; FLUORESCENT DYES; MALE; MICROFLUIDIC ANALYTICAL TECHNIQUES; MICROSCOPY, FLUORESCENCE, MULTIPHOTON; NANOPARTICLES; PARTICLE SIZE; POLYSTYRENES; RATS; RATS, SPRAGUE-DAWLEY; SERUM ALBUMIN, BOVINE;

EID: 84858793649     PISSN: 00906964     EISSN: 15739686     Source Type: Journal    
DOI: 10.1007/s10439-011-0440-0     Document Type: Article

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