Deletion of aquaporin-4 in APP/PS1 mice exacerbates brain Aβ accumulation and memory deficits

Molecular Neurodegeneration

Volumn 10, Issue 1, 2015, Pages

  Xu, Zhiqiang ^a   Xiao, Na ^a   Chen, Yali ^a   Huang, Huang ^a   Marshall, Charles ^b   Gao, Junying ^a   Cai, Zhiyou ^c   Wu, Ting ^d   Hu, Gang ^a   Xiao, Ming ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF KENTUCKY   (United States)

^c HUBEI UNIVERSITY OF MEDICINE   (China)

^d THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Alzheimer's disease; Amyloid beta; AQP4; Astrocytes; Paravascular pathway

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; AQUAPORIN 4; BRAIN DERIVED NEUROTROPHIC FACTOR; INTERLEUKIN 1BETA; INTERLEUKIN 6; POSTSYNAPTIC DENSITY PROTEIN 95; PRESENILIN 1; SYNAPTOPHYSIN; TUMOR NECROSIS FACTOR ALPHA; AQP4 PROTEIN, MOUSE;

AMNESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN ATROPHY; BRAIN CORTEX; COGNITIVE DEFECT; CONTROLLED STUDY; DISEASE EXACERBATION; FEMALE; HIPPOCAMPUS; MALE; MOUSE; NEUROPATHOLOGY; NONHUMAN; PROTEIN DEPLETION; TRANSGENIC MOUSE; VASCULAR AMYLOIDOSIS; ALZHEIMER DISEASE; ANIMAL; BRAIN; INFLAMMATION; MEMORY DISORDER; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; AQUAPORIN 4; BRAIN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CEREBRAL AMYLOID ANGIOPATHY; COGNITION DISORDERS; INFLAMMATION; MEMORY DISORDERS; MICE, TRANSGENIC;

EID: 84959115075     PISSN: None     EISSN: 17501326     Source Type: Journal    
DOI: 10.1186/s13024-015-0056-1     Document Type: Article

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