Diffusion in the extracellular space in brain and tumors

Physical Biology

Volumn 10, Issue 4, 2013, Pages

  Verkman, A S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84881527585     PISSN: 14783967     EISSN: 14783975     Source Type: Journal    
DOI: 10.1088/1478-3975/10/4/045003     Document Type: Article

References (36)

1. Sykova E 2004 Diffusion properties of the brain in health and disease Neurochem. Int. 45 453-66 (Pubitemid 38739472)
2. Sykova E and Nicholson C 2008 Diffusion in brain extracellular space Physiol. Rev. 88 1277-340
3. + and water transport modeled in brain extracellular space following neuroexcitation J. Gen. Physiol. 141 119-32
4. Cordingley G E and Somjen G G 1978 The clearing of excess potassium from extracellular space in spinal cord and cerebral cortex Brain Res. 151 291-306 (Pubitemid 8378394)
5. Netti P A, Hamberg L M, Babich J W, Kierstad D, Graham W, Hunter G H, Wolf G L, Fischman A, Boucher Y and Jain R K 1999 Enhancement of fluid filtration across tumor vessels: implication for delivery of macromolecules Proc. Natl Acad. Sci. USA 96 3137-42 (Pubitemid 29148857)
6. Ribatti D, Nico B, Crivellato E and Vacca A 2007 The structure of the vascular network of tumors Cancer Lett. 248 18-23
7. Vargova L, Homola A, Zamecnik J, Tichy M, Benes V and Sykova E 2003 Diffusion parameters of the extracellular space in human gliomas Glia 42 77-88 (Pubitemid 36427423)
8. Pluen A et al 2001 Role of tumor-host interactions in interstitial diffusion of macromolecules: cranial versus subcutaneous tumors Proc. Natl Acad. Sci. USA 98 4628-33 (Pubitemid 32295027)
9. Alberts B, Bray D, Lewis J, Raff M, Roberts K and Watson J 1994 Extracellular matrix of animals Molecular Biology of the Cell 3rd edn (New York: Garland) pp 971-95
10. Gribbon P M, Maroudas A, Parker K H and Winlove C P 1998 Water and solute transport in the extracellular matrix: physical principles and macromolecular determinants Connective Tissue Biology: Integration and Reductionism ed R K Reed and K Rubin (London: Portland Press) pp 95-124
11. Alexandrakis G, Brown E B, Tong R T, McKee T D, Campbell R B, Boucher Y and Jain R K 2004 Two-photon fluorescence correlation microscopy reveals the two-phase nature of transport in tumors Nature Med. 10 203-7 (Pubitemid 38524893)
12. Brown E B, Campbell R B, Tsuzuki Y, Xu L, Carmeliet P, Fukumura D and Jain R K 2001 In vivo measurement of gene expression, angiogenesis and physiological function in tumors using multiphoton laser scanning microscopy Nature Med. 7 864-8 (Pubitemid 32691644)
13. Brown E, McKee T, diTomaso E, Pluen A, Seed B, Boucher Y and Jain R K 2003 Dynamic imaging of collagen and its modulation in tumors in vivo using second-harmonic generation Nature Med. 9 796-800 (Pubitemid 36749232)
14. Stroh M et al 2005 Quantum dots spectrally distinguish multiple species within the tumor milieu in vivo Nature Med. 11 678-82 (Pubitemid 40868310)
15. Dix J A and Verkman AS 2008 Crowding effects on diffusion in solution and cells Annu. Rev. Biophys. 37 247-63
16. Thiagarajah J R, Kim J K, Magzoub M and Verkman A S 2006 Slowed diffusion in tumors revealed by microfiberoptic epifluorescence photobleaching Nature Methods 3 275-80
17. Zhang H and Verkman A S 2010 Microfiberoptic measurements of extracellular space volume in brain and tumor slices based on fluorescent dye partitioning Biophys. J. 99 1284-91
18. Magzoub M, Zhang H, Dix J A and Verkman A S 2009 Extracellular space volume measured by two-color pulsed dye injection with microfiberoptic fluorescence photodetection Biophys. J. 96 2382-90
19. Zador Z, Magzoub M, Jin S, Manley G T, Papadopoulos M C and Verkman A S 2008 Microfiberoptic fluorescence photobleaching reveals size-dependent macromolecule diffusion in extracellular space deep in brain FASEB J. 22 326-32
20. Magzoub M, Jin S and Verkman A S 2008 Enhanced macromolecule diffusion deep in tumors after enzymatic degradation of extracellular matrix collagen and its associated proteoglycan decorin FASEB J. 22 276-84
21. Rosenberg L E, Downing S J and Segal S 1962 Extracellular space estimation in rat kidney slices using C saccharides and phlorizin Am. J. Physiol. 202 800-4
22. Law R O 1982 Techniques and applications of extracellular space determination in mammalian tissues Experientia 38 411-21 (Pubitemid 12116601)
23. Jackson M J, Cassidy M M and Weller R S 1970 Studies on intestinal fluid transport: 1. Estimation of extracellular space of everted sacs of rat small intestine Biochim. Biophys. Acta. 211 425-35
24. Nicholson C, Chen K C, Hrabetova S and Tao L 2000 Diffusion of molecules in brain extracellular space: theory and experiment Prog. Brain Res. 125 129-54 (Pubitemid 35460795)
25. Nicholson C and Phillips J M 1981 Ion diffusion modified by tortuosity and volume fraction in the extracellular microenvironment of the rat cerebellum J. Physiol. 321 225-57 (Pubitemid 12248093)
26. Binder D, Papadopolous M C, Haggie P M and Verkman A S 2004 In vivo measurement of brain extracellular space diffusion by cortical surface photobleaching J. Neurosci. 24 8049-56 (Pubitemid 39280824)
27. Papadopoulos M C, Binder D K and Verkman A S 2005 Enhanced macromolecular diffusion in brain extracellular space in mouse models of vasogenic edema measured by cortical surface photobleaching FASEB J. 19 425-7 (Pubitemid 40316538)
28. Papadopoulos M C, Kim J K and Verkman A S 2005 Extracellular space diffusion in central nervous system: anisotropic diffusion measured by elliptical surface photobleaching Biophys. J. 89 3660-8 (Pubitemid 41636116)
29. Rusakov D A and Kullmann D M 1998 Geometric and viscous components of the tortuosity of the extracellular space in the brain Proc. Natl Acad. Sci. USA 95 8975-80 (Pubitemid 28350599)
30. Chen K C and Nicholson C 2000 Changes in brain cell shape create residual extracellular space volume and explain tortuosity behavior during osmotic challenge Proc. Natl Acad. Sci. USA 97 8306-11 (Pubitemid 30639668)
31. Hrabe J, Hrabetova S and Segeth K 2004 A model of effective diffusion and tortuosity in the extracellular space of the brain Biophys. J. 87 1606-17 (Pubitemid 39167018)
32. Tao A, Tao L and Nicholson C 2005 Cell cavities increase tortuosity in brain extracellular space J. Theor. Biol. 234 525-36 (Pubitemid 40461860)
33. Nandigam R K and Kroll D M 2007 Three-dimensional modeling of the brain's ECS by minimum configurational energy packing of fluid vesicles Biophys. J. 92 3368-78 (Pubitemid 46698631)
34. Jin S, Zador Z and Verkman A S 2008 Random-walk model of diffusion in 3-dimensions in brain extracellular space: comparison with microfiberoptic photobleaching measurements Biophys. J. 95 1785-94
35. Clague D S and Phillips R J 1996 Hindered diffusion of spherical macromolecules through dilute fibrous media Phys. Fluids 8 1720-31 (Pubitemid 126631622)
36. Stylianopoulos T, Diop-Frimpong B, Munn L L and Jain R K 2012 Diffusion anisotropy in collagen gels and tumors: the effect of fiber network orientation Biophys. J. 99 3119-28