β-Cells are not uniform after all—Novel insights into molecular heterogeneity of insulin-secreting cells

Diabetes, Obesity and Metabolism

Volumn 19, Issue , 2017, Pages 147-152

  Avrahami, Dana ^a   Wang, Yue J ^b   Klochendler, Agnes ^c   Dor, Yuval ^c   Glaser, Benjamin ^a   Kaestner, Klaus H ^b  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c HEBREW UNIVERSITY   (Israel)

Author keywords

mass cytometry; single cell transcriptomics; cell; cell heterogeneity

Indexed keywords

CALCIUM ION; GLUCAGON LIKE PEPTIDE 1; GLUCOSE; INSULIN; BIOLOGICAL MARKER; TRANSCRIPTOME;

CELL DIVISION; CELL FATE; CELL FUNCTION; CELL HETEROGENEITY; CELL MATURATION; CELL PLASTICITY; CELL POLARITY; CELL PROLIFERATION; GENE EXPRESSION; HUMAN; IMAGING; INSULIN RELEASE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; REVIEW; SINGLE CELL ANALYSIS; ANIMAL; CELL LINEAGE; CYTOLOGY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; INSULIN DEPENDENT DIABETES MELLITUS; MEDICAL RESEARCH; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PROCEDURES; SECRETION (PROCESS); SPECIES DIFFERENCE; TRENDS;

ANIMALS; BIOMARKERS; BIOMEDICAL RESEARCH; CELL LINEAGE; DIABETES MELLITUS, TYPE 1; DIABETES MELLITUS, TYPE 2; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; INSULIN; INSULIN-SECRETING CELLS; SINGLE-CELL ANALYSIS; SPECIES SPECIFICITY; TRANSCRIPTOME;

EID: 85029006024     PISSN: 14628902     EISSN: 14631326     Source Type: Journal    
DOI: 10.1111/dom.13019     Document Type: Review

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