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Volumn 8, Issue 1, 2017, Pages

Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation

(15)  Shen, Xia a,b,c   Klarić, Lucija a,c,d   Sharapov, Sodbo e,f   Mangino, Massimo g,h   Ning, Zheng b   Wu, Di i   Trbojević Akmačić, Irena d   Pučić Baković, Maja d   Rudan, Igor a,c   Polašek, Ozren j   Hayward, Caroline c   Spector, Timothy D g   Wilson, James F a,c   Lauc, Gordan d,k   Aulchenko, Yurii S e,f,l  


Author keywords

[No Author keywords available]

Indexed keywords

HLA B ANTIGEN; HLA C ANTIGEN; IMMUNOGLOBULIN G; SWI/SNF RELATED MATRIX ASSOCIATED ACTIN DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY B MEMBER 1; 3-GALACTOSYL-N-ACETYLGLUCOSAMINIDE 4-ALPHA-L-FUCOSYLTRANSFERASE; CELL CYCLE PROTEIN; CEP131 PROTEIN, HUMAN; ELL2 PROTEIN, HUMAN; FUCOSYLTRANSFERASE; MICROTUBULE PROTEIN; TRANSCRIPTION ELONGATION FACTOR;

EID: 85028950118     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-017-00453-3     Document Type: Article
Times cited : (76)

References (45)
  • 2
    • 34347344976 scopus 로고    scopus 로고
    • A new multipoint method for genome-wide association studies by imputation of genotypes
    • Marchini, J., Howie, B., Myers, S., McVean, G. & Donnelly, P. A new multipoint method for genome-wide association studies by imputation of genotypes. Nat. Genet. 39, 906-913 (2007).
    • (2007) Nat. Genet. , vol.39 , pp. 906-913
    • Marchini, J.1    Howie, B.2    Myers, S.3    McVean, G.4    Donnelly, P.5
  • 3
    • 58049204427 scopus 로고    scopus 로고
    • A multivariate test of association
    • Ferreira, M. & Purcell, S. M. A multivariate test of association. Bioinformatics. 25, 132-133 (2009).
    • (2009) Bioinformatics , vol.25 , pp. 132-133
    • Ferreira, M.1    Purcell, S.M.2
  • 4
    • 84866488405 scopus 로고    scopus 로고
    • Moving toward system genetics through multiple trait analysis in genome-wide association studies
    • Shriner, D. Moving toward system genetics through multiple trait analysis in genome-wide association studies. Front. Genet. 3, 1 (2012).
    • (2012) Front. Genet. , vol.3 , pp. 1
    • Shriner, D.1
  • 5
    • 77955166399 scopus 로고    scopus 로고
    • Population structure and cryptic relatedness in genetic association studies
    • Astle, W. & Balding, D. J. Population structure and cryptic relatedness in genetic association studies. Stat. Sci. 24, 451-471 (2009).
    • (2009) Stat. Sci. , vol.24 , pp. 451-471
    • Astle, W.1    Balding, D.J.2
  • 6
    • 84897954264 scopus 로고    scopus 로고
    • Efficient multivariate linear mixed model algorithms for genome-wide association studies
    • Zhou, X. & Stephens, M. Efficient multivariate linear mixed model algorithms for genome-wide association studies. Nat. Methods 11, 407-409 (2014).
    • (2014) Nat. Methods , vol.11 , pp. 407-409
    • Zhou, X.1    Stephens, M.2
  • 7
    • 84938423564 scopus 로고    scopus 로고
    • Efficient set tests for the genetic analysis of correlated traits
    • Casale, F. P., Rakitsch, B., Lippert, C. & Stegle, O. Efficient set tests for the genetic analysis of correlated traits. Nat. Methods 12, 755-758 (2015).
    • (2015) Nat. Methods , vol.12 , pp. 755-758
    • Casale, F.P.1    Rakitsch, B.2    Lippert, C.3    Stegle, O.4
  • 8
    • 84860473457 scopus 로고    scopus 로고
    • MultiPhen: Joint model of multiple phenotypes can increase discovery in GWAS
    • O'Reilly, P. F. et al. MultiPhen: joint model of multiple phenotypes can increase discovery in GWAS. PLoS ONE 7, e34861 (2012).
    • (2012) PLoS ONE , vol.7 , pp. e34861
    • O'Reilly, P.F.1
  • 9
    • 84937010333 scopus 로고    scopus 로고
    • Gene-set and multivariate genome-wide association analysis of oppositional defiant behavior subtypes in attention-deficit/hyperactivity disorder
    • Aebi, M. et al. Gene-set and multivariate genome-wide association analysis of oppositional defiant behavior subtypes in attention-deficit/hyperactivity disorder. Am. J. Med. Genet. B Neuropsychiatr. Genet. 171, 573-588 (2016).
    • (2016) Am. J. Med. Genet. B Neuropsychiatr. Genet. , vol.171 , pp. 573-588
    • Aebi, M.1
  • 10
    • 84879818733 scopus 로고    scopus 로고
    • A unified framework for association analysis with multiple related phenotypes
    • Stephens, M. A unified framework for association analysis with multiple related phenotypes. PLoS ONE 8, e65245 (2013).
    • (2013) PLoS ONE , vol.8 , pp. e65245
    • Stephens, M.1
  • 11
    • 77955505564 scopus 로고    scopus 로고
    • Biological, clinical and population relevance of 95 loci for blood lipids
    • Teslovich, T. M. et al. Biological, clinical and population relevance of 95 loci for blood lipids. Nature. 466, 707-713 (2010).
    • (2010) Nature. , vol.466 , pp. 707-713
    • Teslovich, T.M.1
  • 12
    • 84887099827 scopus 로고    scopus 로고
    • Discovery and refinement of loci associated with lipid levels
    • Global Lipids Genetics Consortium. et al
    • Global Lipids Genetics Consortium. et al. Discovery and refinement of loci associated with lipid levels. Nat. Genet. 45, 1274-1283 (2013).
    • (2013) Nat. Genet. , vol.45 , pp. 1274-1283
  • 13
    • 84866156922 scopus 로고    scopus 로고
    • Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis
    • Inouye, M. et al. Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis. PLoS Genet. 8, e1002907 (2012).
    • (2012) PLoS Genet. , vol.8 , pp. e1002907
    • Inouye, M.1
  • 14
    • 84962271039 scopus 로고    scopus 로고
    • Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA
    • Kettunen, J. et al. Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA. Nat. Commun. 7, 11122 (2016).
    • (2016) Nat. Commun. , vol.7 , pp. 11122
    • Kettunen, J.1
  • 15
    • 84987624284 scopus 로고    scopus 로고
    • PTM-SD: A database of structurally resolved and annotated posttranslational modifications in proteins
    • Craveur, P., Rebehmed, J. & de Brevern, A. G. PTM-SD: A database of structurally resolved and annotated posttranslational modifications in proteins. Database (Oxford) 2014:bau041 (2014).
    • (2014) Database (Oxford) , vol.2014 , pp. bau041
    • Craveur, P.1    Rebehmed, J.2    De Brevern, A.G.3
  • 16
    • 84910679144 scopus 로고    scopus 로고
    • Proteome-wide posttranslational modification statistics: Frequency analysis and curation of the swiss-prot database
    • Khoury, G. A., Baliban, R. C. & Floudas, C. A. Proteome-wide posttranslational modification statistics: frequency analysis and curation of the swiss-prot database. Sci. Rep. 1, 90 (2011).
    • (2011) Sci. Rep. , vol.1 , pp. 90
    • Khoury, G.A.1    Baliban, R.C.2    Floudas, C.A.3
  • 17
    • 0025319470 scopus 로고
    • Agalactosyl IgG in inflammatory bowel disease: Correlation with C-reactive protein
    • Dube, R. et al. Agalactosyl IgG in inflammatory bowel disease: correlation with C-reactive protein. Gut. 31, 431-434 (1990).
    • (1990) Gut. , vol.31 , pp. 431-434
    • Dube, R.1
  • 18
    • 0027082372 scopus 로고
    • Abnormal galactosylation of serum IgG in patients with systemic lupus erythematosus and members of families with high frequency of autoimmune diseases
    • Tomana, M., Schrohenloher, R. E., Reveille, J. D., Arnett, F. C. & Koopman, W. J. Abnormal galactosylation of serum IgG in patients with systemic lupus erythematosus and members of families with high frequency of autoimmune diseases. Rheumatol. Int. 12, 191-194 (1992).
    • (1992) Rheumatol. Int. , vol.12 , pp. 191-194
    • Tomana, M.1    Schrohenloher, R.E.2    Reveille, J.D.3    Arnett, F.C.4    Koopman, W.J.5
  • 19
    • 43549098797 scopus 로고    scopus 로고
    • IgG oligosaccharide alterations are a novel diagnostic marker for disease activity and the clinical course of inflammatory bowel disease
    • Shinzaki, S. et al. IgG oligosaccharide alterations are a novel diagnostic marker for disease activity and the clinical course of inflammatory bowel disease. Am. J. Gastroenterol. 103, 1173-1181 (2008).
    • (2008) Am. J. Gastroenterol. , vol.103 , pp. 1173-1181
    • Shinzaki, S.1
  • 20
    • 84874075704 scopus 로고    scopus 로고
    • National Research Council (US) Committee on Assessing the Importance and Impact of Glycomics and Glycosciences National Academies Press, USA
    • National Research Council (US) Committee on Assessing the Importance and Impact of Glycomics and Glycosciences. Transforming Glycoscience: A Roadmap for the Future (National Academies Press, USA, 2012).
    • (2012) Transforming Glycoscience: A Roadmap for the Future
  • 21
    • 84975742481 scopus 로고    scopus 로고
    • Genomics meets glycomics-the first GWAS study of human N-Glycome identifies HNF1 as a master regulator of plasma protein fucosylation
    • Lauc, G. et al. Genomics meets glycomics-the first GWAS study of human N-Glycome identifies HNF1 as a master regulator of plasma protein fucosylation. PLoS Genet. 6, e1001256 (2010).
    • (2010) PLoS Genet. , vol.6 , pp. e1001256
    • Lauc, G.1
  • 22
    • 81855226434 scopus 로고    scopus 로고
    • Polymorphisms in B3GAT1, SLC9A9 and MGAT5 are associated with variation within the human plasma N-glycome of 3533 European adults
    • Huffman, J. E. et al. Polymorphisms in B3GAT1, SLC9A9 and MGAT5 are associated with variation within the human plasma N-glycome of 3533 European adults. Hum. Mol. Genet. 20, 5000-5011 (2011).
    • (2011) Hum. Mol. Genet. , vol.20 , pp. 5000-5011
    • Huffman, J.E.1
  • 23
    • 84873495247 scopus 로고    scopus 로고
    • Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers
    • Lauc, G. et al. Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. PLoS Genet. 9, e1003225 (2013).
    • (2013) PLoS Genet. , vol.9 , pp. e1003225
    • Lauc, G.1
  • 24
    • 84920269464 scopus 로고    scopus 로고
    • Proteomics. Tissue-based map of the human proteome
    • Uhlén, M. et al. Proteomics. Tissue-based map of the human proteome. Science 347, 1260419 (2015).
    • (2015) Science , vol.347 , pp. 1260419
    • Uhlén, M.1
  • 26
    • 50949106932 scopus 로고    scopus 로고
    • Runs of homozygosity in European populations
    • McQuillan, R. et al. Runs of homozygosity in European populations. Am. J. Hum. Genet. 83, 359-372 (2008).
    • (2008) Am. J. Hum. Genet. , vol.83 , pp. 359-372
    • McQuillan, R.1
  • 28
    • 35048838105 scopus 로고    scopus 로고
    • Genomewide rapid association using mixed model and regression: A fast and simple method for genomewide pedigree-based quantitative trait loci association analysis
    • Aulchenko, Y. S., de Koning, D.-J. & Haley, C. Genomewide rapid association using mixed model and regression: A fast and simple method for genomewide pedigree-based quantitative trait loci association analysis. Genetics 177, 577-585 (2007).
    • (2007) Genetics , vol.177 , pp. 577-585
    • Aulchenko, Y.S.1    De Koning, D.-J.2    Haley, C.3
  • 29
    • 0032714352 scopus 로고    scopus 로고
    • Genomic control for association studies
    • Devlin, B. & Roeder, K. Genomic control for association studies. Biometrics 55, 997-1004 (1999).
    • (1999) Biometrics , vol.55 , pp. 997-1004
    • Devlin, B.1    Roeder, K.2
  • 30
    • 84923096381 scopus 로고    scopus 로고
    • Biological interpretation of genome-wide association studies using predicted gene functions
    • Pers, T. H. et al. Biological interpretation of genome-wide association studies using predicted gene functions. Nat. Commun. 6, 5890 (2015).
    • (2015) Nat. Commun. , vol.6 , pp. 5890
    • Pers, T.H.1
  • 32
    • 33751370454 scopus 로고    scopus 로고
    • Fucosylation in prokaryotes and eukaryotes
    • Ma, B., Simala-Grant, J. L. & Taylor, D. E. Fucosylation in prokaryotes and eukaryotes. Glycobiology 16, 158R-184R (2006).
    • (2006) Glycobiology , vol.16 , pp. 158R-184R
    • Ma, B.1    Simala-Grant, J.L.2    Taylor, D.E.3
  • 33
    • 58849104457 scopus 로고    scopus 로고
    • The HLA genomic loci map: Expression, interaction, diversity and disease
    • Shiina, T., Hosomichi, K., Inoko, H. & Kulski, J. K. The HLA genomic loci map: expression, interaction, diversity and disease. J. Hum. Genet. 54, 15-39 (2009).
    • (2009) J. Hum. Genet. , vol.54 , pp. 15-39
    • Shiina, T.1    Hosomichi, K.2    Inoko, H.3    Kulski, J.K.4
  • 34
    • 0032191170 scopus 로고    scopus 로고
    • Aiolos regulates B cell activation and maturation to effector state
    • Wang, J. H. et al. Aiolos regulates B cell activation and maturation to effector state. Immunity. 9, 543-553 (1998).
    • (1998) Immunity. , vol.9 , pp. 543-553
    • Wang, J.H.1
  • 36
    • 33746888249 scopus 로고    scopus 로고
    • Anti-inflammatory activity of immunoglobulin G resulting from Fc sialylation
    • Kaneko, Y. Anti-inflammatory activity of immunoglobulin G resulting from Fc sialylation. Science 313, 670-673 (2006).
    • (2006) Science , vol.313 , pp. 670-673
    • Kaneko, Y.1
  • 37
    • 70349456510 scopus 로고    scopus 로고
    • Transcription elongation factor ELL2 directs immunoglobulin secretion in plasma cells by stimulating altered RNA processing
    • Martincic, K., Alkan, S. A., Cheatle, A., Borghesi, L. & Milcarek, C. Transcription elongation factor ELL2 directs immunoglobulin secretion in plasma cells by stimulating altered RNA processing. Nat. Immunol. 10, 1102-1109 (2009).
    • (2009) Nat. Immunol. , vol.10 , pp. 1102-1109
    • Martincic, K.1    Alkan, S.A.2    Cheatle, A.3    Borghesi, L.4    Milcarek, C.5
  • 38
    • 41349103917 scopus 로고    scopus 로고
    • SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout
    • Vitart, V. et al. SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout. Nat. Genet. 40, 437-442 (2008).
    • (2008) Nat. Genet. , vol.40 , pp. 437-442
    • Vitart, V.1
  • 39
    • 67549136520 scopus 로고    scopus 로고
    • Genome-wide association study of biochemical traits in Korcula Island, Croatia
    • Zemunik, T. et al. Genome-wide association study of biochemical traits in Korcula Island, Croatia. Croat. Med. J. 50, 23-33 (2009).
    • (2009) Croat. Med. J. , vol.50 , pp. 23-33
    • Zemunik, T.1
  • 41
    • 0035670640 scopus 로고    scopus 로고
    • Are twins and singletons comparable A study of diseaserelated and lifestyle characteristics in adult women
    • Andrew, T. et al. Are twins and singletons comparable A study of diseaserelated and lifestyle characteristics in adult women. Twin. Res. 4, 464-477 (2001).
    • (2001) Twin. Res. , vol.4 , pp. 464-477
    • Andrew, T.1
  • 42
    • 34447324105 scopus 로고    scopus 로고
    • GenABEL: An R library for genome-wide association analysis
    • Aulchenko, Y. S., Ripke, S., Isaacs, A. & van Duijn, C. M. GenABEL: An R library for genome-wide association analysis. Bioinformatics 23, 1294-1296 (2007).
    • (2007) Bioinformatics , vol.23 , pp. 1294-1296
    • Aulchenko, Y.S.1    Ripke, S.2    Isaacs, A.3    Van Duijn, C.M.4
  • 43
  • 44
    • 0000020001 scopus 로고
    • Some new test criteria in multivariate analysis
    • Pillai, K. Some new test criteria in multivariate analysis. Ann. Math. Stat. 26, 117-121 (1955).
    • (1955) Ann. Math. Stat. , vol.26 , pp. 117-121
    • Pillai, K.1


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