Tet1-mediated DNA demethylation involves in neuron damage induced by bilirubin in vitro

Toxicology Mechanisms and Methods

Volumn 28, Issue 1, 2018, Pages 55-61

  Gou, Panhong ^a   Qi, Xiaoling ^a   Yuan, Rui ^a   Li, Haojie ^a   Gao, Xiaoling ^b   Wang, Junling ^a   Zhang, Benzhong ^a  

^a LANZHOU UNIVERSITY   (China)

^b Gansu Provincial Peoples Hospital   (China)

Author keywords

DNA demethylation; Klotho; ROS; Tet 1; UCB

Indexed keywords

10 11 TRANSLATION METHYLCYTOSINE DIOXYGENASE PROTEIN; BETA ACTIN; BILIRUBIN; CASPASE 3; KLOTHO PROTEIN; MESSENGER RNA; PROTEIN; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; BETA GLUCURONIDASE; CASP3 PROTEIN, RAT; DIOXYGENASE; TET1 PROTEIN, RAT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DEMETHYLATION; DNA DEMETHYLATION; DNA METHYLATION; DRUG EXPOSURE; ENZYME ACTIVITY; GENE EXPRESSION; IN VITRO STUDY; MALE; MTT ASSAY; NERVE CELL; NERVE CELL CULTURE; NERVE CELL LESION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANIMAL; APOPTOSIS; BRAIN CORTEX; CELL CULTURE; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECT; ENZYMOLOGY; FEMALE; GENETICS; METABOLISM; PATHOLOGY; PRIMARY CELL CULTURE; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; TIME FACTOR; TOXICITY AND INTOXICATION;

ANIMALS; APOPTOSIS; BILIRUBIN; CASPASE 3; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; DIOXYGENASES; DNA DEMETHYLATION; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GLUCURONIDASE; MALE; NEURONS; NEUROTOXICITY SYNDROMES; OXIDATIVE STRESS; PRIMARY CELL CULTURE; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 85028548846     PISSN: 15376516     EISSN: 15376524     Source Type: Journal    
DOI: 10.1080/15376516.2017.1357775     Document Type: Article

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