-
1
-
-
84862777054
-
Lysine methylation of FOXO3 regulates oxidative stress-induced neuronal cell death
-
Xie, Q. et al. Lysine methylation of FOXO3 regulates oxidative stress-induced neuronal cell death. EMBO Rep. 13, 371-377, doi:10.1038/embor.2012.25 (2012).
-
(2012)
EMBO Rep
, vol.13
, pp. 371-377
-
-
Xie, Q.1
-
2
-
-
18844434370
-
Oxidative stress in the brain: Novel cellular targets that govern survival during neurodegenerative disease
-
Chong, Z. Z., Li, F.,Maiese, K. Oxidative stress in the brain: novel cellular targets that govern survival during neurodegenerative disease. Prog Neurobiol. 75, 207-246, doi:10.1016/j.pneurobio.2005.02.004 (2005).
-
(2005)
Prog Neurobiol
, vol.75
, pp. 207-246
-
-
Chong, Z.Z.1
Li, F.2
Maiese, K.3
-
3
-
-
65649149752
-
Regulation of neuronal cell death by MST1-FOXO1 signaling
-
Yuan, Z. et al. Regulation of neuronal cell death by MST1-FOXO1 signaling. J Biol Chem. 284, 11285-11292, doi:10.1074/jbc.M900461200 (2009).
-
(2009)
J Biol Chem
, vol.284
, pp. 11285-11292
-
-
Yuan, Z.1
-
4
-
-
1542381057
-
Cell cycle regulation of neuronal apoptosis in development and disease
-
Becker, E. B., Bonni, A. Cell cycle regulation of neuronal apoptosis in development and disease. Prog Neurobiol. 72, 1-25, doi:10.1016/j.pneurobio.2003.12.005 (2004).
-
(2004)
Prog Neurobiol
, vol.72
, pp. 1-25
-
-
Becker, E.B.1
Bonni, A.2
-
5
-
-
0032947526
-
Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain
-
Ikonomidou, C. Blockade of NMDA Receptors and Apoptotic Neurodegeneration in the Developing Brain. Science 283, 70-74, doi:10.1126/science.283.5398.70 (1999).
-
(1999)
Science
, vol.283
, pp. 70-74
-
-
Ikonomidou, C.1
-
6
-
-
33645037717
-
DNA methylation and apoptosis
-
Gopisetty, G., Ramachandran, K., Singal, R. DNA methylation and apoptosis. Mol Immunol. 43, 1729-1740, doi:10.1016/j.molimm.2005.11.010 (2006).
-
(2006)
Mol Immunol
, vol.43
, pp. 1729-1740
-
-
Gopisetty, G.1
Ramachandran, K.2
Singal, R.3
-
7
-
-
81255143014
-
Epigenetic regulation of motor neuron cell death through DNA methylation
-
Chestnut, B. A. et al. Epigenetic regulation of motor neuron cell death through DNA methylation. J Neurosci. 31, 16619-16636, doi:10.1523/JNEUROSCI.1639-11.2011 (2011).
-
(2011)
J Neurosci
, vol.31
, pp. 16619-16636
-
-
Chestnut, B.A.1
-
8
-
-
16444381345
-
Dynamic expression of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the central nervous system
-
Feng, J., Chang, H., Li, E., Fan, G. Dynamic expression of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the central nervous system. JNeurosci Res. 79, 734-746, doi:10.1002/jnr.20404 (2005).
-
(2005)
JNeurosci Res
, vol.79
, pp. 734-746
-
-
Feng, J.1
Chang, H.2
Li, E.3
Fan, G.4
-
9
-
-
77956189495
-
Role of Tet proteins in 5mC to 5hmC conversion ES-cell self-renewal and inner cell mass specification
-
Ito, S. et al. Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature 466, 1129-1133, doi:10.1038/nature09303 (2010).
-
(2010)
Nature
, vol.466
, pp. 1129-1133
-
-
Ito, S.1
-
10
-
-
84893373754
-
Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells
-
Huang, Y. et al. Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells. Proc Natl Acad Sci USA 111, 1361-1366, doi:10.1073/pnas.1322921111 (2014).
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. 1361-1366
-
-
Huang, Y.1
-
11
-
-
84878591266
-
Subtelomeric hotspots of aberrant 5-hydroxymethylcytosinemediated epigenetic modifications during reprogramming to pluripotency
-
Wang, T. et al. Subtelomeric hotspots of aberrant 5-hydroxymethylcytosinemediated epigenetic modifications during reprogramming to pluripotency. Nat Cell Biol. 15, 700-711, doi:10.1038/ncb2748 (2013).
-
(2013)
Nat Cell Biol
, vol.15
, pp. 700-711
-
-
Wang, T.1
-
12
-
-
84884241288
-
Tet1 is critical for neuronal activity-regulated gene expression and memory extinction
-
Rudenko, A. et al. Tet1 is critical for neuronal activity-regulated gene expression and memory extinction. Neuron 79, 1109-1122, doi:10.1016/j.neuron.2013.08.003 (2013).
-
(2013)
Neuron
, vol.79
, pp. 1109-1122
-
-
Rudenko, A.1
-
13
-
-
84881178902
-
Tet1 regulates adult hippocampal neurogenesis and cognition
-
Zhang, R. R. et al. Tet1 regulates adult hippocampal neurogenesis and cognition. Cell Stem Cell. 13, 237-245, doi:10.1016/j.stem.2013.05.006 (2013).
-
(2013)
Cell Stem Cell
, vol.13
, pp. 237-245
-
-
Zhang, R.R.1
-
14
-
-
13244275048
-
5-Aza-cytidine is a potent inhibitor of DNA methyltransferase 3a and induces apoptosis in HCT-116 colon cancer cells via Gadd45-and p53-dependent mechanisms
-
Schneider-Stock, R. et al. 5-Aza-cytidine is a potent inhibitor of DNA methyltransferase 3a and induces apoptosis in HCT-116 colon cancer cells via Gadd45-and p53-dependent mechanisms. J Pharmacol Exp Ther. 312, 525-536, doi:10.1124/jpet.104.074195 (2005).
-
(2005)
J Pharmacol Exp Ther
, vol.312
, pp. 525-536
-
-
Schneider-Stock, R.1
-
15
-
-
84870618095
-
TRPC6 inhibited NMDA receptor activities and protected neurons from ischemic excitotoxicity
-
Li, H. et al. TRPC6 inhibited NMDA receptor activities and protected neurons from ischemic excitotoxicity. J Neurochem. 123, 1010-1018, doi:10.1111/jnc.12045 (2012).
-
(2012)
J Neurochem
, vol.123
, pp. 1010-1018
-
-
Li, H.1
-
16
-
-
33646934067
-
A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span
-
Lehtinen, M. K. et al. A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span. Cell 125, 987-1001, doi:10.1016/j.cell.2006.03.046 (2006).
-
(2006)
Cell
, vol.125
, pp. 987-1001
-
-
Lehtinen, M.K.1
-
17
-
-
79956302047
-
TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity
-
Williams, K. et al. TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity. Nature 473, 343-348, doi:10.1038/nature10066 (2011).
-
(2011)
Nature
, vol.473
, pp. 343-348
-
-
Williams, K.1
-
18
-
-
84873707539
-
Combined deficiency of Tet1 and Tet2 causes epigenetic abnormalities but is compatible with postnatal development
-
Dawlaty, M. M. et al. Combined deficiency of Tet1 and Tet2 causes epigenetic abnormalities but is compatible with postnatal development. Dev Cell 24, 310-323, doi:10.1016/j.devcel.2012.12.015 (2013).
-
(2013)
Dev Cell
, vol.24
, pp. 310-323
-
-
Dawlaty, M.M.1
-
19
-
-
79955538247
-
Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain
-
Guo, Junjie, U., Su, Y., Zhong, C., Ming, G.-l., Song, H. Hydroxylation of 5-Methylcytosine by TET1 Promotes Active DNA Demethylation in the Adult Brain. Cell 145, 423-434, doi:10.1016/j.cell.2011.03.022 (2011).
-
(2011)
Cell
, vol.145
, pp. 423-434
-
-
Guo Junjie, U.1
Su, Y.2
Zhong, C.3
Ming, G.-L.4
Song, H.5
-
20
-
-
0030724491
-
Mutation of the mouse klotho gene leads to a syndrome resembling ageing
-
Kuro-o, M. et al. Mutation of the mouse klotho gene leads to a syndrome resembling ageing. Nature 390, 45-51 (1997).
-
(1997)
Nature
, vol.390
, pp. 45-51
-
-
Kuro-O, M.1
-
21
-
-
84863338125
-
Suppression of Klotho expression by proteinbound uremic toxins is associated with increased DNA methyltransferase expression and DNA hypermethylation
-
Sun, C. Y., Chang, S. C., Wu,M. S. Suppression of Klotho expression by proteinbound uremic toxins is associated with increased DNA methyltransferase expression and DNA hypermethylation. Kidney Int. 81, 640-650, doi:10.1038/ki.2011.445 (2012).
-
(2012)
Kidney Int
, vol.81
, pp. 640-650
-
-
Sun, C.Y.1
Chang, S.C.2
Wu, M.S.3
-
22
-
-
77957837438
-
Inhibition of TRPC6 degradation suppresses ischemic brain damage in rats
-
Du,W., Huang, J., Yao, H., Zhou, K., Duan, B.,Wang, Y. Z. Inhibition of TRPC6 degradation suppresses ischemic brain damage in rats. J Clin Invest. 120, 3480-3492 (2010).
-
(2010)
J Clin Invest
, vol.120
, pp. 3480-3492
-
-
Du, W.1
Huang, J.2
Yao, H.3
Zhou, K.4
Duan, B.5
Wang, Y.Z.6
-
23
-
-
0036241207
-
Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways
-
Hardingham, G. E., Fukunaga, Y., Bading, H. Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways. Nat Neurosci. 5, 405-414, doi:10.1038/nn835 (2002).
-
(2002)
Nat Neurosci
, vol.5
, pp. 405-414
-
-
Hardingham, G.E.1
Fukunaga, Y.2
Bading, H.3
-
24
-
-
33749342012
-
Klotho RNAi induces premature senescence of human cells via a p53/p21 dependent pathway
-
de Oliveira, R. M. Klotho RNAi induces premature senescence of human cells via a p53/p21 dependent pathway. FEBS Lett. 580, 5753-5758, doi:10.1016/j.febslet.2006.09.036 (2006).
-
(2006)
FEBS Lett
, vol.580
, pp. 5753-5758
-
-
De Oliveira, R.M.1
|