메뉴 건너뛰기




Volumn 2016, Issue 1, 2016, Pages 148-157

Beyond killing: Can we find new ways to manage infection?

Author keywords

Anti virulence drugs; Damage limitation; Disease tolerance; Evolution; Infection; Microbiota

Indexed keywords

ANTIBIOTIC AGENT; PENICILLIN DERIVATIVE; VIRULENCE FACTOR;

EID: 85028348971     PISSN: None     EISSN: 20506201     Source Type: Journal    
DOI: 10.1093/EMPH/EOW012     Document Type: Note
Times cited : (68)

References (70)
  • 1
    • 10944272743 scopus 로고    scopus 로고
    • Antibacterial resistance worldwide: causes, challenges and responses
    • Levy SB, Marshall B. Antibacterial resistance worldwide: causes, challenges and responses. Nat Med 2004;10: S122-9
    • (2004) Nat Med , vol.10 , pp. S122-S129
    • Levy, S.B.1    Marshall, B.2
  • 2
    • 84897039080 scopus 로고    scopus 로고
    • Overcoming the current deadlock in antibiotic research
    • Schäberle TF, Hack IM. Overcoming the current deadlock in antibiotic research. Trends Microbiol 2014;22:165-7
    • (2014) Trends Microbiol , vol.22 , pp. 165-167
    • Schäberle, T.F.1    Hack, I.M.2
  • 3
    • 84873513511 scopus 로고    scopus 로고
    • Incentives aim to boost antibiotic development
    • Roberts JP. Incentives aim to boost antibiotic development. Nat Biotechnol 2012;30:735
    • (2012) Nat Biotechnol , vol.30 , pp. 735
    • Roberts, J.P.1
  • 4
    • 84930246440 scopus 로고    scopus 로고
    • Strategies to Discover Novel Antimicrobials to Cope with Emerging Medical Needs
    • Marinelli F, Genilloud O (eds.)
    • Genilloud O, Vicente F. Strategies to Discover Novel Antimicrobials to Cope with Emerging Medical Needs. In: Marinelli F, Genilloud O (eds.). Antimicrobials. Springer: Berlin Heidelberg, 2014, 327-60
    • (2014) Antimicrobials , pp. 327-360
    • Genilloud, O.1    Vicente, F.2
  • 5
    • 2442477676 scopus 로고    scopus 로고
    • A novel beta-lactamase activity from a penicillin-binding protein of Treponema pallidum and why syphilis is still treatable with penicillin
    • Cha JY, Ishiwata A, Mobashery S. A novel beta-lactamase activity from a penicillin-binding protein of Treponema pallidum and why syphilis is still treatable with penicillin. J Biol Chem 2004;279:14917-21
    • (2004) J Biol Chem , vol.279 , pp. 14917-14921
    • Cha, J.Y.1    Ishiwata, A.2    Mobashery, S.3
  • 6
    • 17344362378 scopus 로고    scopus 로고
    • Why have group a streptococci remained susceptible to penicillin? Report on a symposium
    • Horn DL, Zabriskie JB, Austrian R et al. Why have group a streptococci remained susceptible to penicillin? Report on a symposium. Clin Infect Dis 1998;26:1341-5
    • (1998) Clin Infect Dis , vol.26 , pp. 1341-1345
    • Horn, D.L.1    Zabriskie, J.B.2    Austrian, R.3
  • 7
    • 65649124513 scopus 로고    scopus 로고
    • Drug interactions and the evolution of antibiotic resistance
    • Yeh PJ, Hegreness MJ, Aiden AP et al. Drug interactions and the evolution of antibiotic resistance. Nat Rev Microbiol 2009;7:460
    • (2009) Nat Rev Microbiol , vol.7 , pp. 460
    • Yeh, P.J.1    Hegreness, M.J.2    Aiden, A.P.3
  • 8
    • 77949569493 scopus 로고    scopus 로고
    • Antibiotic resistance and its cost: is it possible to reverse resistance?
    • Andersson DI,Hughes D. Antibiotic resistance and its cost: is it possible to reverse resistance? Nat Rev Microbiol 2010;8:260-71
    • (2010) Nat Rev Microbiol , vol.8 , pp. 260-271
    • Andersson, D.I.1    Hughes, D.2
  • 9
    • 84893728073 scopus 로고    scopus 로고
    • Limiting damage during infection: lessons from infection tolerance for novel therapeutics
    • Vale PF, Fenton A, Brown SP. Limiting damage during infection: lessons from infection tolerance for novel therapeutics. PLoS Biol 2014;12:e1001769
    • (2014) PLoS Biol , vol.12
    • Vale, P.F.1    Fenton, A.2    Brown, S.P.3
  • 10
    • 84908690682 scopus 로고    scopus 로고
    • A theoretical examination of the relative importance of evolution management and drug development for managing resistance
    • McClure NS, Day T. A theoretical examination of the relative importance of evolution management and drug development for managing resistance. Proc R Soc B Biol Sci 2014;281:20141861
    • (2014) Proc R Soc B Biol Sci , vol.281
    • McClure, N.S.1    Day, T.2
  • 11
    • 84936765949 scopus 로고    scopus 로고
    • Dominant drug targets suppress the emergence of antiviral resistance
    • Tanner EJ, Liu H, Oberste MS et al. Dominant drug targets suppress the emergence of antiviral resistance. eLife 2014;3:e03830
    • (2014) eLife , vol.3
    • Tanner, E.J.1    Liu, H.2    Oberste, M.S.3
  • 12
    • 84893786916 scopus 로고    scopus 로고
    • Targeting virulence: can we make evolution-proof drugs?
    • Allen RC, Popat R, Diggle SP et al. Targeting virulence: can we make evolution-proof drugs? Nat Rev Microbiol 2014; 12:300-8
    • (2014) Nat Rev Microbiol , vol.12 , pp. 300-308
    • Allen, R.C.1    Popat, R.2    Diggle, S.P.3
  • 13
    • 75249090304 scopus 로고    scopus 로고
    • Antivirulence drugs to target bacterial secretion systems
    • Baron C. Antivirulence drugs to target bacterial secretion systems. Curr Opin Microbiol 2010;13:100-5
    • (2010) Curr Opin Microbiol , vol.13 , pp. 100-105
    • Baron, C.1
  • 14
    • 75949092121 scopus 로고    scopus 로고
    • Anti-virulence strategies to combat bacteria-mediated disease
    • RaskoDA, SperandioV.Anti-virulence strategies to combat bacteria-mediated disease. Nat Rev Drug Discov 2010;9:117-28
    • (2010) Nat Rev Drug Discov , vol.9 , pp. 117-128
    • Rasko, D.A.1    Sperandio, V.2
  • 15
    • 33747603020 scopus 로고    scopus 로고
    • Broad-spectrum biofilm inhibition by a secreted bacterial polysaccharide
    • Valle J, Re SD, Henry N et al. Broad-spectrum biofilm inhibition by a secreted bacterial polysaccharide. Proc Natl Acad Sci USA 2006;103:12558-63
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 12558-12563
    • Valle, J.1    Re, S.D.2    Henry, N.3
  • 16
    • 84942543705 scopus 로고    scopus 로고
    • A small-molecule antivirulence agent for treating Clostridium difficile infection
    • Bender KO, Garland M, Ferreyra JA et al. A small-molecule antivirulence agent for treating Clostridium difficile infection. Sci Transl Med 2015;7:306ra148
    • (2015) Sci Transl Med , vol.7
    • Bender, K.O.1    Garland, M.2    Ferreyra, J.A.3
  • 17
    • 40449088993 scopus 로고    scopus 로고
    • A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence
    • Liu C-I, Liu GY, Song Y et al. A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence. Science 2008;319:1391-4
    • (2008) Science , vol.319 , pp. 1391-1394
    • Liu, C.-I.1    Liu, G.Y.2    Song, Y.3
  • 18
    • 85038628631 scopus 로고    scopus 로고
    • Galliummediated siderophore quenching as an evolutionarily robust antibacterial treatment
    • Ross-Gillespie A, Weigert M, Brown SP et al. Galliummediated siderophore quenching as an evolutionarily robust antibacterial treatment. Evol Med Public Health 2014;2014:18-29
    • (2014) Evol Med Public Health , vol.2014 , pp. 18-29
    • Ross-Gillespie, A.1    Weigert, M.2    Brown, S.P.3
  • 19
    • 0021325455 scopus 로고
    • Clindamycin-induced suppression of toxic-shock syndrome-associated exotoxin production
    • Schlievert PM, Kelly JA. Clindamycin-induced suppression of toxic-shock syndrome-associated exotoxin production. J Infect Dis 1984;149:471
    • (1984) J Infect Dis , vol.149 , pp. 471
    • Schlievert, P.M.1    Kelly, J.A.2
  • 20
    • 84899670756 scopus 로고    scopus 로고
    • Antivirulence activity of azithromycin in Pseudomonas aeruginosa
    • Imperi F, Leoni L, Visca P. Antivirulence activity of azithromycin in Pseudomonas aeruginosa. Antimicrob Resist Chemother 2014;5:178
    • (2014) Antimicrob Resist Chemother , vol.5 , pp. 178
    • Imperi, F.1    Leoni, L.2    Visca, P.3
  • 21
    • 84876936620 scopus 로고    scopus 로고
    • Repurposing the antimycotic drug flucytosine for suppression of Pseudomonas aeruginosa pathogenicity
    • Imperi F, Massai F, Facchini M et al. Repurposing the antimycotic drug flucytosine for suppression of Pseudomonas aeruginosa pathogenicity. Proc Natl Acad Sci USA 2013;110:7458-63
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 7458-7463
    • Imperi, F.1    Massai, F.2    Facchini, M.3
  • 22
    • 84868244170 scopus 로고    scopus 로고
    • Drugs that target pathogen public goods are robust against evolved drug resistance
    • Pepper JW. Drugs that target pathogen public goods are robust against evolved drug resistance. Evol Appl 2012;5:757-61
    • (2012) Evol Appl , vol.5 , pp. 757-761
    • Pepper, J.W.1
  • 23
    • 57249108290 scopus 로고    scopus 로고
    • Defeating pathogen drug resistance: guidance from evolutionary theory
    • Pepper JW. Defeating pathogen drug resistance: guidance from evolutionary theory. Evol Int J Org Evol 2008;62: 3185-91
    • (2008) Evol Int J Org Evol , vol.62 , pp. 3185-3191
    • Pepper, J.W.1
  • 24
    • 80455130021 scopus 로고    scopus 로고
    • The sociomicrobiology of antivirulence drug resistance: a proof of concept
    • Mellbye B, Schuster M. The sociomicrobiology of antivirulence drug resistance: a proof of concept. mBio 2011;2:e00131-11
    • (2011) mBio , vol.2
    • Mellbye, B.1    Schuster, M.2
  • 25
    • 84867184096 scopus 로고    scopus 로고
    • Adaptive and mutational resistance: role of porins and efflux pumps in drug resistance
    • Fernandez L, Hancock REW. Adaptive and mutational resistance: role of porins and efflux pumps in drug resistance. Clin Microbiol Rev 2012;25:661-81
    • (2012) Clin Microbiol Rev , vol.25 , pp. 661-681
    • Fernandez, L.1    Hancock, R.E.W.2
  • 26
    • 84874904560 scopus 로고    scopus 로고
    • Exploiting quorum sensing to confuse bacterial pathogens
    • LaSarre B, Federle MJ. Exploiting quorum sensing to confuse bacterial pathogens. Microbiol Mol Biol Rev MMBR 2013;77:73-111
    • (2013) Microbiol Mol Biol Rev MMBR , vol.77 , pp. 73-111
    • LaSarre, B.1    Federle, M.J.2
  • 27
    • 84922527244 scopus 로고    scopus 로고
    • Tissue damage control in disease tolerance
    • Soares MP, Gozzelino R, Weis S. Tissue damage control in disease tolerance. Trends Immunol 2014;35:483-94
    • (2014) Trends Immunol , vol.35 , pp. 483-494
    • Soares, M.P.1    Gozzelino, R.2    Weis, S.3
  • 28
  • 31
    • 77958023093 scopus 로고    scopus 로고
    • A central role for free heme in the pathogenesis of severe sepsis
    • Larsen R, Gozzelino R, Jeney V et al. A central role for free heme in the pathogenesis of severe sepsis. Sci Transl Med 2010;2:51ra71
    • (2010) Sci Transl Med , vol.2
    • Larsen, R.1    Gozzelino, R.2    Jeney, V.3
  • 32
    • 79955528559 scopus 로고    scopus 로고
    • Sickle hemoglobin confers tolerance to plasmodium infection
    • Ferreira A, Marguti I, Bechmann I et al. Sickle hemoglobin confers tolerance to plasmodium infection. Cell 2011;145: 398-409
    • (2011) Cell , vol.145 , pp. 398-409
    • Ferreira, A.1    Marguti, I.2    Bechmann, I.3
  • 33
    • 84878756188 scopus 로고    scopus 로고
    • Role of tissue protection in lethal respiratory viral-bacterial coinfection
    • Jamieson AM, Pasman L, Yu S et al. Role of tissue protection in lethal respiratory viral-bacterial coinfection. Science 2013;340:1230-4
    • (2013) Science , vol.340 , pp. 1230-1234
    • Jamieson, A.M.1    Pasman, L.2    Yu, S.3
  • 34
    • 84887559345 scopus 로고    scopus 로고
    • Anthracyclines induce DNA damage response-mediated protection against severe sepsis
    • Figueiredo N, Chora A, Raquel H et al. Anthracyclines induce DNA damage response-mediated protection against severe sepsis. Immunity 2013;39:874-84
    • (2013) Immunity , vol.39 , pp. 874-884
    • Figueiredo, N.1    Chora, A.2    Raquel, H.3
  • 36
    • 84936985324 scopus 로고    scopus 로고
    • Bats as "special" reservoirs for emerging zoonotic pathogens
    • Brook CE, Dobson AP. Bats as "special" reservoirs for emerging zoonotic pathogens. Trends Microbiol 2015;23:172-80
    • (2015) Trends Microbiol , vol.23 , pp. 172-180
    • Brook, C.E.1    Dobson, A.P.2
  • 37
    • 0034435565 scopus 로고    scopus 로고
    • Defining tolerance as a norm of reaction
    • Simms E. Defining tolerance as a norm of reaction. Evol Ecol 2000;14:563-70
    • (2000) Evol Ecol , vol.14 , pp. 563-570
    • Simms, E.1
  • 38
    • 38449094810 scopus 로고    scopus 로고
    • Disentangling genetic variation for resistance and tolerance to infectious diseases in animals
    • Råberg L, Sim D, Read AF. Disentangling genetic variation for resistance and tolerance to infectious diseases in animals. Science 2007;318:812-4
    • (2007) Science , vol.318 , pp. 812-814
    • Råberg, L.1    Sim, D.2    Read, A.F.3
  • 39
    • 84947569624 scopus 로고    scopus 로고
    • Health trajectories reveal the dynamic contributions of host genetic resistance and tolerance to infection outcome
    • Lough G, Kyriazakis I, Bergmann S et al. Health trajectories reveal the dynamic contributions of host genetic resistance and tolerance to infection outcome. Proc R Soc B 2015;282:20152151
    • (2015) Proc R Soc B , vol.282
    • Lough, G.1    Kyriazakis, I.2    Bergmann, S.3
  • 40
    • 80053295729 scopus 로고    scopus 로고
    • Tracing Personalized Health Curves during Infections
    • Schneider DS. Tracing Personalized Health Curves during Infections. PLoS Biol 2011;9:e1001158
    • (2011) PLoS Biol , vol.9
    • Schneider, D.S.1
  • 41
    • 84876087873 scopus 로고    scopus 로고
    • Novel methods for quantifying individual host response to infectious pathogens for genetic analyses
    • Doeschl-Wilson AB, Bishop SC, Kyriazakis I et al. Novel methods for quantifying individual host response to infectious pathogens for genetic analyses. Front Livest Genomics 2012;3:266
    • (2012) Front Livest Genomics , vol.3 , pp. 266
    • Doeschl-Wilson, A.B.1    Bishop, S.C.2    Kyriazakis, I.3
  • 42
    • 84880923555 scopus 로고    scopus 로고
    • Type 2 immunity and wound healing: evolutionary refinement of adaptive immunity by helminths
    • Gause WC, Wynn TA, Allen JE. Type 2 immunity and wound healing: evolutionary refinement of adaptive immunity by helminths. Nat Rev Immunol 2013;13:607-14
    • (2013) Nat Rev Immunol , vol.13 , pp. 607-614
    • Gause, W.C.1    Wynn, T.A.2    Allen, J.E.3
  • 43
    • 79957583362 scopus 로고    scopus 로고
    • Evolution of Th2 immunity: a rapid repair response to tissue destructive pathogens
    • Allen JE, Wynn TA. Evolution of Th2 immunity: a rapid repair response to tissue destructive pathogens. PLoS Pathog 2011;7:e1002003
    • (2011) PLoS Pathog , vol.7
    • Allen, J.E.1    Wynn, T.A.2
  • 44
    • 84922902948 scopus 로고    scopus 로고
    • Host protective roles of type 2 immunity: parasite killing and tissue repair, flip sides of the same coin
    • Allen JE, Sutherland TE. Host protective roles of type 2 immunity: parasite killing and tissue repair, flip sides of the same coin. Semin Immunol 2014;26:329-40
    • (2014) Semin Immunol , vol.26 , pp. 329-340
    • Allen, J.E.1    Sutherland, T.E.2
  • 45
    • 58549116149 scopus 로고    scopus 로고
    • Virulence evolution and the trade-off hypothesis: history, current state of affairs and the future
    • Alizon S, Hurford A, MideoNet al. Virulence evolution and the trade-off hypothesis: history, current state of affairs and the future. J Evol Biol 2009;22:245-59
    • (2009) J Evol Biol , vol.22 , pp. 245-259
    • Alizon, S.1    Hurford, A.2    Mideo, N.3
  • 46
    • 84927565502 scopus 로고    scopus 로고
    • Role of diseaseassociated tolerance in infectious superspreaders
    • Gopinath S, Lichtman JS, BouleyDMet al. Role of diseaseassociated tolerance in infectious superspreaders. Proc Natl Acad Sci USA 2014;111:15780-5
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. 15780-15785
    • Gopinath, S.1    Lichtman, J.S.2    Bouley, D.M.3
  • 47
    • 33747077510 scopus 로고    scopus 로고
    • The evolution of parasites in response to tolerance in their hosts: the good, the bad, and apparent commensalism
    • Miller MR, White A, Boots M. The evolution of parasites in response to tolerance in their hosts: the good, the bad, and apparent commensalism. Evol Int JOrg Evol 2006;60:945-56
    • (2006) Evol Int JOrg Evol , vol.60 , pp. 945-956
    • Miller, M.R.1    White, A.2    Boots, M.3
  • 48
    • 84862767819 scopus 로고    scopus 로고
    • Evolution of virulence in opportunistic pathogens: generalism, plasticity, and control
    • Brown SP, Cornforth DM, Mideo N. Evolution of virulence in opportunistic pathogens: generalism, plasticity, and control. Trends Microbiol 2012;20:336-42
    • (2012) Trends Microbiol , vol.20 , pp. 336-342
    • Brown, S.P.1    Cornforth, D.M.2    Mideo, N.3
  • 49
    • 84858376593 scopus 로고    scopus 로고
    • The impact of the gut microbiota on human health: an integrative view
    • Clemente JC, Ursell LK, Parfrey LW et al. The impact of the gut microbiota on human health: an integrative view. Cell 2012;148:1258-70
    • (2012) Cell , vol.148 , pp. 1258-1270
    • Clemente, J.C.1    Ursell, L.K.2    Parfrey, L.W.3
  • 50
    • 0034707908 scopus 로고    scopus 로고
    • Exploitation of gut bacteria in the locust
    • Dillon RJ, Vennard CT, Charnley AK. Exploitation of gut bacteria in the locust. Nature 2000;403:851
    • (2000) Nature , vol.403 , pp. 851
    • Dillon, R.J.1    Vennard, C.T.2    Charnley, A.K.3
  • 51
    • 82755162640 scopus 로고    scopus 로고
    • Socially transmitted gut microbiota protect bumble bees against an intestinal parasite
    • Koch H, Schmid-Hempel P. Socially transmitted gut microbiota protect bumble bees against an intestinal parasite. Proc Natl Acad Sci USA 2011;108:19288-92
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 19288-19292
    • Koch, H.1    Schmid-Hempel, P.2
  • 52
    • 33749997498 scopus 로고    scopus 로고
    • Reciprocal gut microbiota transplants from zebrafish and mice to germ-free recipients reveal host habitat selection
    • Rawls JF, MahowaldMA, Ley RE et al. Reciprocal gut microbiota transplants from zebrafish and mice to germ-free recipients reveal host habitat selection. Cell 2006;127:423-33
    • (2006) Cell , vol.127 , pp. 423-433
    • Rawls, J.F.1    Mahowald, M.A.2    Ley, R.E.3
  • 53
    • 84920809160 scopus 로고    scopus 로고
    • Gut microbiota elicits a protective immune response against malaria transmission
    • Yilmaz B, Portugal S, Tran TM et al. Gut microbiota elicits a protective immune response against malaria transmission. Cell 2014;159:1277-89
    • (2014) Cell , vol.159 , pp. 1277-1289
    • Yilmaz, B.1    Portugal, S.2    Tran, T.M.3
  • 54
    • 70350344717 scopus 로고    scopus 로고
    • SYNTHESIS: Evolutionary ecology of microbial wars: within-host competition and (incidental) virulence
    • Brown SP, Fredrik Inglis R, Taddei F. SYNTHESIS: Evolutionary ecology of microbial wars: within-host competition and (incidental) virulence. Evol Appl 2009;2:32-9
    • (2009) Evol Appl , vol.2 , pp. 32-39
    • Brown, S.P.1    Fredrik Inglis, R.2    Taddei, F.3
  • 55
    • 9644257146 scopus 로고    scopus 로고
    • The role of pyocyanin in Pseudomonas aeruginosa infection
    • Lau GW, Hassett DJ, Ran H et al. The role of pyocyanin in Pseudomonas aeruginosa infection. Trends Mol Med 2004;10:599-606
    • (2004) Trends Mol Med , vol.10 , pp. 599-606
    • Lau, G.W.1    Hassett, D.J.2    Ran, H.3
  • 56
    • 77951051419 scopus 로고    scopus 로고
    • The role of innate immune responses in the outcome of interspecies competition for colonization of mucosal surfaces
    • Lysenko ES, Ratner AJ, Nelson AL et al. The role of innate immune responses in the outcome of interspecies competition for colonization of mucosal surfaces. PLoS Pathog 2005;1:e1
    • (2005) PLoS Pathog , vol.1
    • Lysenko, E.S.1    Ratner, A.J.2    Nelson, A.L.3
  • 57
    • 35649026345 scopus 로고    scopus 로고
    • Salmonella enterica serovar typhimurium exploits inflammation to compete with the intestinal microbiota
    • Stecher B, Robbiani R, WalkerAWet al. Salmonella enterica serovar typhimurium exploits inflammation to compete with the intestinal microbiota. PLoS Biol 2007;5:2177-89
    • (2007) PLoS Biol , vol.5 , pp. 2177-2189
    • Stecher, B.1    Robbiani, R.2    Walker, A.W.3
  • 58
    • 84943626950 scopus 로고    scopus 로고
    • Engineering microbiomes to improve plant and animal health
    • Mueller UG, Sachs JL. Engineering microbiomes to improve plant and animal health. Trends Microbiol 2015; 23:606-17
    • (2015) Trends Microbiol , vol.23 , pp. 606-617
    • Mueller, U.G.1    Sachs, J.L.2
  • 59
    • 84878656561 scopus 로고    scopus 로고
    • Clostridium difficile: a cause of diarrhea in children
    • Moreno MA, Furtner F, Rivara FP. Clostridium difficile: a cause of diarrhea in children. JAMA Pediatr 2013;167:592
    • (2013) JAMA Pediatr , vol.167 , pp. 592
    • Moreno, M.A.1    Furtner, F.2    Rivara, F.P.3
  • 61
    • 84882283827 scopus 로고    scopus 로고
    • Fecal transplantation for recurrent Clostridium difficile infection in older adults: a review
    • Burke KE, Lamont JT. Fecal transplantation for recurrent Clostridium difficile infection in older adults: a review. J Am Geriatr Soc 2013;61:1394-8
    • (2013) J Am Geriatr Soc , vol.61 , pp. 1394-1398
    • Burke, K.E.1    Lamont, J.T.2
  • 62
    • 84873019302 scopus 로고    scopus 로고
    • Duodenal infusion of donor feces for recurrent Clostridium difficile
    • van Nood E, Vrieze A, Nieuwdorp M et al. Duodenal infusion of donor feces for recurrent Clostridium difficile. N Engl J Med 2013;368:407-15
    • (2013) N Engl J Med , vol.368 , pp. 407-415
    • van Nood, E.1    Vrieze, A.2    Nieuwdorp, M.3
  • 63
    • 84925500413 scopus 로고    scopus 로고
    • Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile
    • Buffie CG, Bucci V, Stein RR et al. Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile. Nature 2015;517:205-8
    • (2015) Nature , vol.517 , pp. 205-208
    • Buffie, C.G.1    Bucci, V.2    Stein, R.R.3
  • 64
    • 84945964162 scopus 로고    scopus 로고
    • Bacteriocin productionaugmentsnichecompetitionbyenterococci inthemammalian gastrointestinal tract
    • Kommineni S, Bretl DJ, Lam V et al. Bacteriocin productionaugmentsnichecompetitionbyenterococci inthemammalian gastrointestinal tract. Nature 2015;526:719-22
    • (2015) Nature , vol.526 , pp. 719-722
    • Kommineni, S.1    Bretl, D.J.2    Lam, V.3
  • 65
    • 84936988461 scopus 로고    scopus 로고
    • The effects of spatial structure, frequency dependence and resistance evolution on the dynamics of toxin-mediated microbial invasions
    • Libberton B, Horsburgh MJ, Brockhurst MA. The effects of spatial structure, frequency dependence and resistance evolution on the dynamics of toxin-mediated microbial invasions. Evol Appl 2015;8:738-50
    • (2015) Evol Appl , vol.8 , pp. 738-750
    • Libberton, B.1    Horsburgh, M.J.2    Brockhurst, M.A.3
  • 66
    • 84961219421 scopus 로고    scopus 로고
    • Rapid evolution of microbe-mediated protection against pathogens in a worm host
    • March
    • King KC, Brockhurst MA, Vasieva O et al. Rapid evolution of microbe-mediated protection against pathogens in a worm host. ISME J 2016, March. http://dx.doi.org/10. 1038/ismej.2015.259
    • (2016) ISME J
    • King, K.C.1    Brockhurst, M.A.2    Vasieva, O.3
  • 67
    • 77954920911 scopus 로고    scopus 로고
    • Engineered bacterial communication prevents Vibrio cholerae virulence in an infant mouse model
    • Duan F, March JC. Engineered bacterial communication prevents Vibrio cholerae virulence in an infant mouse model. Proc Natl Acad Sci USA 2010;107:11260-4
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 11260-11264
    • Duan, F.1    March, J.C.2
  • 68
    • 84945359684 scopus 로고    scopus 로고
    • Disease tolerance mediated by microbiome E. coli involves inflammasome and IGF-1 signaling
    • Schieber AMP, Lee YM, Chang MW et al. Disease tolerance mediated by microbiome E. coli involves inflammasome and IGF-1 signaling. Science 2015;350:558-63
    • (2015) Science , vol.350 , pp. 558-563
    • Schieber, A.M.P.1    Lee, Y.M.2    Chang, M.W.3
  • 69
    • 85020595408 scopus 로고    scopus 로고
    • Microbiome engineering could select for more virulent pathogens
    • September
    • McNally L, Vale PF,BrownSP.Microbiome engineering could select for more virulent pathogens. bioRxiv 2015;027854, September. doi:10.1101/027854
    • (2015) bioRxiv
    • McNally, L.1    Vale, P.F.2    Brown, S.P.3
  • 70
    • 84938690612 scopus 로고    scopus 로고
    • Biofilm formation as a response to ecological competition
    • Oliveira NM, Martinez-Garcia E, Xavier J et al. Biofilm formation as a response to ecological competition. PLoS Biol 2015;13:e1002191
    • (2015) PLoS Biol , vol.13
    • Oliveira, N.M.1    Martinez-Garcia, E.2    Xavier, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.