Disease tolerance mediated by microbiome E. coli involves inflammasome and IGF-1 signaling

Science

Volumn 350, Issue 6260, 2015, Pages 558-563

  Schieber, Alexandria M Palaferri ^a   Lee, Yujung Michelle ^a   Chang, Max W ^a   Leblanc, Mathias ^a   Collins, Brett ^a   Downes, Michael ^a   Evans, Ronald M ^a,b   Ayres, Janelle S ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPICILLIN; ANTIBIOTIC AGENT; CARBON DIOXIDE; DEXTRAN SULFATE; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 6; METRONIDAZOLE; NEOMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SOMATOMEDIN C; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; VANCOMYCIN; APOPTOSIS REGULATORY PROTEIN; CALCIUM BINDING PROTEIN; IPAF PROTEIN, MOUSE;

BACTERIUM; COMMENSAL; INFECTIVITY; METABOLISM; MICROBIAL ACTIVITY; MUSCLE; PATHOGEN; PNEUMONIA; RODENT; SKELETON; TOLERANCE;

ANIMAL EXPERIMENT; ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL STRAIN; BURKHOLDERIA THAILANDENSIS; COMMENSAL ESCHERICHIA COLI; CONTROLLED STUDY; CRITICALLY ILL PATIENT; CROHN DISEASE; DISEASE SEVERITY; DOWN REGULATION; EDEMA; ENTERITIS; EPITHELIUM CELL; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTION; FAT MASS; FIBROSIS; FOOD DEPRIVATION; FOOD INTAKE; HUMAN; HYPERPLASIA; INFLAMMATION; INFLAMMATORY BOWEL DISEASE; INTESTINAL TISSUE; INTESTINE FLORA; INTESTINE INJURY; LUNG GAS EXCHANGE; METABOLIC RATE; MICROBIAL COMMUNITY; MICROBIOME; MOUSE; MULTILOCUS SEQUENCE TYPING; MUSCLE ATROPHY; MUSCLE MASS; NONHUMAN; OXYGEN CONSUMPTION; PATHOGEN LOAD; PATHOGENESIS; PRIORITY JOURNAL; RNA GENE; RNA SEQUENCE; SALMONELLA ENTERICA SEROVAR TYPHIMURIUM; SALMONELLOSIS; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; THERMOGENESIS; WEIGHT REDUCTION; ANIMAL; BIOSYNTHESIS; BURKHOLDERIA; BURKHOLDERIA INFECTION; C57BL MOUSE; COMPLICATION; IMMUNOLOGY; INTESTINE; METABOLISM; MICROBIOLOGY; MICROFLORA; WASTING SYNDROME;

BURKHOLDERIA THAILANDENSIS; ESCHERICHIA COLI; MUS; SALMONELLA TYPHIMURIUM;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; BIOSYNTHETIC PATHWAYS; BURKHOLDERIA; BURKHOLDERIA INFECTIONS; CALCIUM-BINDING PROTEINS; ESCHERICHIA COLI; INFLAMMASOMES; INSULIN-LIKE GROWTH FACTOR I; INTESTINES; MICE; MICE, INBRED C57BL; MICROBIOTA; MUSCLE, SKELETAL; PHOSPHATIDYLINOSITOL 3-KINASE; PROTO-ONCOGENE PROTEINS C-AKT; SALMONELLA INFECTIONS; SALMONELLA TYPHIMURIUM; WASTING SYNDROME;

EID: 84945359684     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aac6468     Document Type: Article

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