PPP1R1B-STARD3 chimeric fusion transcript in human gastric cancer promotes tumorigenesis through activation of PI3K/AKT signaling

Oncogene

Volumn 33, Issue 46, 2014, Pages 5341-5347

  Yun, S M ^a   Yoon, K ^a   Lee, S ^b,c   Kim, E ^a   Kong, S H ^d,e   Choe, J ^a   Kang, J M ^a   Han, T S ^d   Kim, P ^a   Choi, Y ^a   Jho, S ^b   Yoo, H ^a   Bhak, J ^b,c   Yang, H K ^d,e   Kim, S J ^a  

^a CHA University   (South Korea)

^b Personal Genomics Institute   (South Korea)

^c Theragen ETEX Bio Institute   (South Korea)

^d Seoul National University Graduate School   (South Korea)

^e Seoul National University College of Medicine   (South Korea)

Author keywords

fusion transcript; gastric cancer; transcriptome sequencing

Indexed keywords

2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; CARRIER PROTEIN; CHROMONE DERIVATIVE; ENZYME INHIBITOR; MEMBRANE PROTEIN; MORPHOLINE DERIVATIVE; ONCOPROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOPROTEIN DARPP 32; PPP1R1B PROTEIN, HUMAN; PPP1R1B-STARD3 ONCOGENE FUSION PROTEIN, HUMAN; PROTEIN KINASE B; STARD3 PROTEIN, HUMAN;

ADULT; AGED; ANIMAL; ANTAGONISTS AND INHIBITORS; CARCINOGENESIS; DRUG EFFECTS; FEMALE; GENETICS; HUMAN; MALE; METABOLISM; MIDDLE AGED; NUDE MOUSE; PATHOLOGY; PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STOMACH TUMOR; TUMOR CELL LINE; TUMOR VOLUME; VERY ELDERLY; WESTERN BLOTTING; XENOGRAFT;

ADULT; AGED; AGED, 80 AND OVER; ANIMALS; BLOTTING, WESTERN; CARCINOGENESIS; CARRIER PROTEINS; CELL LINE, TUMOR; CHROMONES; DOPAMINE AND CAMP-REGULATED PHOSPHOPROTEIN 32; ENZYME INHIBITORS; FEMALE; HUMANS; MALE; MEMBRANE PROTEINS; MICE, NUDE; MIDDLE AGED; MORPHOLINES; ONCOGENE PROTEINS, FUSION; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STOMACH NEOPLASMS; TRANSPLANTATION, HETEROLOGOUS; TUMOR BURDEN;

EID: 85027952419     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2013.472     Document Type: Article

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