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Volumn 10, Issue 4, 2014, Pages 363-371

Are NSAIDs Coming Back to Colorectal Cancer Therapy or Not?

Author keywords

Adjuvant therapy; Aspirin; Colorectal cancer; COX 2; HLA 1; NSAIDs; PIK3CA

Indexed keywords

ACETYLSALICYLIC ACID; B RAF KINASE; BETA CATENIN; BIOLOGICAL MARKER; CAPECITABINE; CELECOXIB; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; GROWTH DIFFERENTIATION FACTOR 15; HLA A1 ANTIGEN; IRINOTECAN; NONSTEROID ANTIINFLAMMATORY AGENT; PROTEIN; PROTEIN PIK3CA; ROFECOXIB; UNCLASSIFIED DRUG;

EID: 85027949789     PISSN: 15563790     EISSN: 15563804     Source Type: Journal    
DOI: 10.1007/s11888-014-0247-0     Document Type: Review
Times cited : (4)

References (72)
  • 1
    • 78049485263 scopus 로고    scopus 로고
    • Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
    • PID: 21351269, COI: 1:CAS:528:DC%2BC3cXhtlWhs7fO
    • Ferlay J, Shin H-R, Bray F, Forman D, Mathers C, Parkin DM. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer. 2010;127(12):2893–917.
    • (2010) Int J Cancer , vol.127 , Issue.12 , pp. 2893-2917
    • Ferlay, J.1    Shin, H.-R.2    Bray, F.3    Forman, D.4    Mathers, C.5    Parkin, D.M.6
  • 2
    • 67650315187 scopus 로고    scopus 로고
    • Improved overall survival with oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment in stage II or III colon cancer in the MOSAIC trial
    • PID: 19451431
    • André T, Boni C, Navarro M, Tabernero J, Hickish T, Topham C, et al. Improved overall survival with oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment in stage II or III colon cancer in the MOSAIC trial. J Clin Oncol. 2009;27(19):3109–16.
    • (2009) J Clin Oncol , vol.27 , Issue.19 , pp. 3109-3116
    • André, T.1    Boni, C.2    Navarro, M.3    Tabernero, J.4    Hickish, T.5    Topham, C.6
  • 3
    • 36849064682 scopus 로고    scopus 로고
    • Adjuvant chemotherapy versus observation in patients with colorectal cancer: a randomised study
    • Quasar Collaborative Group. Adjuvant chemotherapy versus observation in patients with colorectal cancer: a randomised study. Lancet. 2007;370(9604):2020–9.
    • (2007) Lancet , vol.370 , Issue.9604 , pp. 2020-2029
    • Quasar Collaborative Group1
  • 4
    • 83355163988 scopus 로고    scopus 로고
    • The utility of aspirin in dukes C and high risk dukes B colorectal cancer—the ASCOLT study: study protocol for a randomized controlled trial
    • PID: 22168568, COI: 1:CAS:528:DC%2BC38XivVWltrY%3D, Trial protocol for ongoing multicentre randomised controlled trial of low-dose (200 mg) aspirin vs. placebo in adjuvant treatment of CRC
    • Ali R, Toh HC, Chia WK. The utility of aspirin in dukes C and high risk dukes B colorectal cancer—the ASCOLT study: study protocol for a randomized controlled trial. Trials. 2011;12:261. Trial protocol for ongoing multicentre randomised controlled trial of low-dose (200 mg) aspirin vs. placebo in adjuvant treatment of CRC.
    • (2011) Trials , vol.12 , pp. 261
    • Ali, R.1    Toh, H.C.2    Chia, W.K.3
  • 5
    • 2542615200 scopus 로고    scopus 로고
    • Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer
    • PID: 15175436, COI: 1:CAS:528:DC%2BD2cXks1Gjt78%3D
    • Andre T, Boni C, Mounedji-Boudiaf L, Navarro M, Tabernero J, Hickish T, et al. Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer. N Engl J Med. 2004;350(23):2343–51.
    • (2004) N Engl J Med , vol.350 , Issue.23 , pp. 2343-2351
    • Andre, T.1    Boni, C.2    Mounedji-Boudiaf, L.3    Navarro, M.4    Tabernero, J.5    Hickish, T.6
  • 6
    • 21244497388 scopus 로고    scopus 로고
    • Capecitabine as adjuvant treatment for stage III colon cancer
    • PID: 15987918, COI: 1:CAS:528:DC%2BD2MXls1SktL0%3D
    • Twelves C, Wong A, Nowacki MP, Abt M, Burris 3rd H, Carrato A, et al. Capecitabine as adjuvant treatment for stage III colon cancer. N Engl J Med. 2005;352(26):2696–704.
    • (2005) N Engl J Med , vol.352 , Issue.26 , pp. 2696-2704
    • Twelves, C.1    Wong, A.2    Nowacki, M.P.3    Abt, M.4    Burris, H.5    Carrato, A.6
  • 7
    • 84887121545 scopus 로고    scopus 로고
    • The impact of anti-inflammatory agents on the outcome of patients with colorectal cancer
    • PID: 23773805, COI: 1:CAS:528:DC%2BC3sXpslGhtbY%3D
    • Park JH, McMillan DC, Horgan PG, Roxburgh CS. The impact of anti-inflammatory agents on the outcome of patients with colorectal cancer. Cancer Treat Rev. 2014;40(1):68–77.
    • (2014) Cancer Treat Rev , vol.40 , Issue.1 , pp. 68-77
    • Park, J.H.1    McMillan, D.C.2    Horgan, P.G.3    Roxburgh, C.S.4
  • 8
    • 84899071584 scopus 로고    scopus 로고
    • Anti-inflammatory/antioxidant use in long-term maintenance cancer therapy: a new therapeutic approach to disease progression and recurrence
    • PID: 24587831
    • Crawford S. Anti-inflammatory/antioxidant use in long-term maintenance cancer therapy: a new therapeutic approach to disease progression and recurrence. Ther Adv Med Oncol. 2014;6(2):52–68.
    • (2014) Ther Adv Med Oncol , vol.6 , Issue.2 , pp. 52-68
    • Crawford, S.1
  • 9
    • 84860467522 scopus 로고    scopus 로고
    • Effects of regular aspirin on long-term cancer incidence and metastasis: a systematic comparison of evidence from observational studies versus randomised trials
    • PID: 22440112, COI: 1:CAS:528:DC%2BC38Xmslyhsbs%3D, Systematic summary of data regarding aspirin effect on CRC outcomes from randomised and observational studies
    • Algra AM, Rothwell PM. Effects of regular aspirin on long-term cancer incidence and metastasis: a systematic comparison of evidence from observational studies versus randomised trials. Lancet Oncol. 2012;13(5):518–27. Systematic summary of data regarding aspirin effect on CRC outcomes from randomised and observational studies.
    • (2012) Lancet Oncol , vol.13 , Issue.5 , pp. 518-527
    • Algra, A.M.1    Rothwell, P.M.2
  • 10
    • 0037421985 scopus 로고    scopus 로고
    • A randomized trial of aspirin to prevent colorectal adenomas
    • PID: 12621133, COI: 1:CAS:528:DC%2BD3sXhvVOitrw%3D
    • Baron JA, Cole BF, Sandler RS, Haile RW, Ahnen D, Bresalier R, et al. A randomized trial of aspirin to prevent colorectal adenomas. N Engl J Med. 2003;348(10):891–9.
    • (2003) N Engl J Med , vol.348 , Issue.10 , pp. 891-899
    • Baron, J.A.1    Cole, B.F.2    Sandler, R.S.3    Haile, R.W.4    Ahnen, D.5    Bresalier, R.6
  • 11
    • 83955161674 scopus 로고    scopus 로고
    • Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial
    • PID: 22036019
    • Burn J, Gerdes AM, Macrae F, Mecklin JP, Moeslein G, Olschwang S, et al. Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial. Lancet. 2011;378(9809):2081–7.
    • (2011) Lancet , vol.378 , Issue.9809 , pp. 2081-2087
    • Burn, J.1    Gerdes, A.M.2    Macrae, F.3    Mecklin, J.P.4    Moeslein, G.5    Olschwang, S.6
  • 12
    • 84855556537 scopus 로고    scopus 로고
    • Aspirin in the chemoprevention of colorectal neoplasia: an overview
    • COI: 1:CAS:528:DC%2BC38XjvValtb0%3D
    • Chan AT, Arber N, Burn J, Chia WK, Elwood P, Hull MA, et al. Aspirin in the chemoprevention of colorectal neoplasia: an overview. Cancer Prev Res (Phila). 2012;5(2):164–78.
    • (2012) Cancer Prev Res (Phila) , vol.5 , Issue.2 , pp. 164-178
    • Chan, A.T.1    Arber, N.2    Burn, J.3    Chia, W.K.4    Elwood, P.5    Hull, M.A.6
  • 13
    • 34248157118 scopus 로고    scopus 로고
    • Effect of aspirin on long-term risk of colorectal cancer: consistent evidence from randomised and observational studies
    • PID: 17499602, COI: 1:CAS:528:DC%2BD2sXltF2qsrk%3D
    • Flossmann E, Rothwell PM. Effect of aspirin on long-term risk of colorectal cancer: consistent evidence from randomised and observational studies. Lancet. 2007;369(9573):1603–13.
    • (2007) Lancet , vol.369 , Issue.9573 , pp. 1603-1613
    • Flossmann, E.1    Rothwell, P.M.2
  • 14
    • 84863412124 scopus 로고    scopus 로고
    • Short-term effects of daily aspirin on cancer incidence, mortality, and non-vascular death: analysis of the time course of risks and benefits in 51 randomised controlled trials
    • PID: 22440946, COI: 1:CAS:528:DC%2BC38XktlGkurw%3D
    • Rothwell PM, Price JF, Fowkes FG, Zanchetti A, Roncaglioni MC, Tognoni G, et al. Short-term effects of daily aspirin on cancer incidence, mortality, and non-vascular death: analysis of the time course of risks and benefits in 51 randomised controlled trials. Lancet. 2012;379(9826):1602–12.
    • (2012) Lancet , vol.379 , Issue.9826 , pp. 1602-1612
    • Rothwell, P.M.1    Price, J.F.2    Fowkes, F.G.3    Zanchetti, A.4    Roncaglioni, M.C.5    Tognoni, G.6
  • 15
    • 78650215449 scopus 로고    scopus 로고
    • Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials
    • PID: 20970847, COI: 1:CAS:528:DC%2BC3cXhsVGitbfF
    • Rothwell PM, Wilson M, Elwin CE, Norrving B, Algra A, Warlow CP, et al. Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials. Lancet. 2010;376(9754):1741–50.
    • (2010) Lancet , vol.376 , Issue.9754 , pp. 1741-1750
    • Rothwell, P.M.1    Wilson, M.2    Elwin, C.E.3    Norrving, B.4    Algra, A.5    Warlow, C.P.6
  • 16
    • 84863399038 scopus 로고    scopus 로고
    • Effect of daily aspirin on risk of cancer metastasis: a study of incident cancers during randomised controlled trials
    • PID: 22440947, COI: 1:CAS:528:DC%2BC38XktlGku7c%3D
    • Rothwell PM, Wilson M, Price JF, Belch JF, Meade TW, Mehta Z. Effect of daily aspirin on risk of cancer metastasis: a study of incident cancers during randomised controlled trials. Lancet. 2012;379(9826):1591–601.
    • (2012) Lancet , vol.379 , Issue.9826 , pp. 1591-1601
    • Rothwell, P.M.1    Wilson, M.2    Price, J.F.3    Belch, J.F.4    Meade, T.W.5    Mehta, Z.6
  • 17
    • 80053994835 scopus 로고    scopus 로고
    • Aspirin and cancer: has aspirin been overlooked as an adjuvant therapy?
    • PID: 21847126, COI: 1:CAS:528:DC%2BC3MXhtlahsrvM
    • Langley RE, Burdett S, Tierney JF, Cafferty F, Parmar MKB, Venning G. Aspirin and cancer: has aspirin been overlooked as an adjuvant therapy? Br J Cancer. 2011;105(8):1107–13.
    • (2011) Br J Cancer , vol.105 , Issue.8 , pp. 1107-1113
    • Langley, R.E.1    Burdett, S.2    Tierney, J.F.3    Cafferty, F.4    Parmar, M.K.B.5    Venning, G.6
  • 18
    • 82455188359 scopus 로고    scopus 로고
    • Pharmacology and cellular/molecular mechanisms of action of aspirin and non-aspirin NSAIDs in colorectal cancer
    • PID: 22122764
    • Schrör K. Pharmacology and cellular/molecular mechanisms of action of aspirin and non-aspirin NSAIDs in colorectal cancer. Best Pract Res Clin Gastroenterol. 2011;25(4):473–84.
    • (2011) Best Pract Res Clin Gastroenterol , vol.25 , Issue.4 , pp. 473-484
    • Schrör, K.1
  • 19
    • 78650825618 scopus 로고    scopus 로고
    • Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials
    • PID: 21144578, COI: 1:CAS:528:DC%2BC3MXms1Wk
    • Rothwell PM, Fowkes FG, Belch JF, Ogawa H, Warlow CP, Meade TW. Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials. Lancet. 2011;377(9759):31–41.
    • (2011) Lancet , vol.377 , Issue.9759 , pp. 31-41
    • Rothwell, P.M.1    Fowkes, F.G.2    Belch, J.F.3    Ogawa, H.4    Warlow, C.P.5    Meade, T.W.6
  • 20
    • 78650840096 scopus 로고    scopus 로고
    • Ibuprofen inhibits activation of nuclear β-catenin in human colon adenomas and induces the phosphorylation of GSK-3β
    • COI: 1:CAS:528:DC%2BC3MXhvVyqu7s%3D
    • Greenspan EJ, Madigan JP, Boardman LA, Rosenberg DW. Ibuprofen inhibits activation of nuclear β-catenin in human colon adenomas and induces the phosphorylation of GSK-3β. Cancer Prev Res. 2011;4(1):161–71.
    • (2011) Cancer Prev Res , vol.4 , Issue.1 , pp. 161-171
    • Greenspan, E.J.1    Madigan, J.P.2    Boardman, L.A.3    Rosenberg, D.W.4
  • 21
    • 72949123788 scopus 로고    scopus 로고
    • The effect of aspirin in the recurrence of colorectal adenomas: a meta-analysis of randomized controlled trials
    • COI: 1:STN:280:DC%2BD1Mnpt12kuw%3D%3D
    • Gao F, Liao C, Liu L, Tan A, Cao Y, Mo Z. The effect of aspirin in the recurrence of colorectal adenomas: a meta-analysis of randomized controlled trials. Color Dis. 2009;11(9):893–901.
    • (2009) Color Dis , vol.11 , Issue.9 , pp. 893-901
    • Gao, F.1    Liao, C.2    Liu, L.3    Tan, A.4    Cao, Y.5    Mo, Z.6
  • 22
    • 0842329914 scopus 로고    scopus 로고
    • Sulindac targets nuclear beta-catenin accumulation and Wnt signalling in adenomas of patients with familial adenomatous polyposis and in human colorectal cancer cell lines
    • PID: 14710233, COI: 1:CAS:528:DC%2BD2cXhtFKmsw%3D%3D
    • Boon EMJ, Keller JJ, Wormhoudt TAM, Giardiello FM, Offerhaus GJA, van der Neut R, et al. Sulindac targets nuclear beta-catenin accumulation and Wnt signalling in adenomas of patients with familial adenomatous polyposis and in human colorectal cancer cell lines. Br J Cancer. 2004;90(1):224–9.
    • (2004) Br J Cancer , vol.90 , Issue.1 , pp. 224-229
    • Boon, E.M.J.1    Keller, J.J.2    Wormhoudt, T.A.M.3    Giardiello, F.M.4    Offerhaus, G.J.A.5    van der Neut, R.6
  • 23
    • 57749107623 scopus 로고    scopus 로고
    • Effect of aspirin or resistant starch on colorectal neoplasia in the Lynch syndrome
    • PID: 19073976, COI: 1:CAS:528:DC%2BD1cXhsV2ktrvM
    • Burn J, Bishop DT, Mecklin JP, Macrae F, Moslein G, Olschwang S, et al. Effect of aspirin or resistant starch on colorectal neoplasia in the Lynch syndrome. N Engl J Med. 2008;359(24):2567–78.
    • (2008) N Engl J Med , vol.359 , Issue.24 , pp. 2567-2578
    • Burn, J.1    Bishop, D.T.2    Mecklin, J.P.3    Macrae, F.4    Moslein, G.5    Olschwang, S.6
  • 24
    • 0027197062 scopus 로고
    • Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis
    • PID: 8385741, COI: 1:STN:280:DyaK3s3is1Sjtg%3D%3D
    • Giardiello FM, Hamilton SR, Krush AJ, Piantadosi S, Hylind LM, Celano P, et al. Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis. N Engl J Med. 1993;328(18):1313–6.
    • (1993) N Engl J Med , vol.328 , Issue.18 , pp. 1313-1316
    • Giardiello, F.M.1    Hamilton, S.R.2    Krush, A.J.3    Piantadosi, S.4    Hylind, L.M.5    Celano, P.6
  • 25
    • 84899808030 scopus 로고    scopus 로고
    • Aspirin as adjuvant therapy for stage III colon cancer: standard of care?
    • PID: 24686732
    • Neugut AI. Aspirin as adjuvant therapy for stage III colon cancer: standard of care? JAMA Intern Med. 2014;174(5):739–41.
    • (2014) JAMA Intern Med , vol.174 , Issue.5 , pp. 739-741
    • Neugut, A.I.1
  • 26
    • 84865485411 scopus 로고    scopus 로고
    • Aspirin and cancer: trials and observational studies
    • PID: 22888142, COI: 1:CAS:528:DC%2BC38Xht1ygtLjL
    • Baron JA. Aspirin and cancer: trials and observational studies. J Natl Cancer Inst. 2012;104(16):1199–200.
    • (2012) J Natl Cancer Inst , vol.104 , Issue.16 , pp. 1199-1200
    • Baron, J.A.1
  • 27
  • 28
    • 84894294540 scopus 로고    scopus 로고
    • Low-dose aspirin use after diagnosis of colorectal cancer does not increase survival: a case-control analysis of a population-based cohort
    • PID: 24239563, COI: 1:CAS:528:DC%2BC2cXlt1eitA%3D%3D
    • Cardwell CR, Kunzmann AT, Cantwell MM, Hughes C, Baron JA, Powe DG, et al. Low-dose aspirin use after diagnosis of colorectal cancer does not increase survival: a case-control analysis of a population-based cohort. Gastroenterology. 2014;146(3):700–708.e2.
    • (2014) Gastroenterology , vol.146 , Issue.3 , pp. 700-708
    • Cardwell, C.R.1    Kunzmann, A.T.2    Cantwell, M.M.3    Hughes, C.4    Baron, J.A.5    Powe, D.G.6
  • 29
    • 68849123400 scopus 로고    scopus 로고
    • Aspirin use and survival after diagnosis of colorectal cancer
    • PID: 19671906, COI: 1:CAS:528:DC%2BD1MXpslynu7w%3D
    • Chan AT, Ogino S, Fuchs CS. Aspirin use and survival after diagnosis of colorectal cancer. JAMA. 2009;302(6):649–58.
    • (2009) JAMA , vol.302 , Issue.6 , pp. 649-658
    • Chan, A.T.1    Ogino, S.2    Fuchs, C.S.3
  • 30
    • 84867101876 scopus 로고    scopus 로고
    • Aspirin as adjuvant therapy for colorectal cancer—reinterpreting paradigms
    • PID: 22910681, COI: 1:CAS:528:DC%2BC38XhsVartr%2FE
    • Chia WK, Ali R, Toh HC. Aspirin as adjuvant therapy for colorectal cancer—reinterpreting paradigms. Nat Rev Clin Oncol. 2012;9(10):561–70.
    • (2012) Nat Rev Clin Oncol , vol.9 , Issue.10 , pp. 561-570
    • Chia, W.K.1    Ali, R.2    Toh, H.C.3
  • 31
    • 79952533784 scopus 로고    scopus 로고
    • Prediagnostic non-steroidal anti-inflammatory drug use and survival after diagnosis of colorectal cancer
    • PID: 21051449
    • Coghill AE, Newcomb PA, Campbell PT, Burnett-Hartman AN, Adams SV, Poole EM, et al. Prediagnostic non-steroidal anti-inflammatory drug use and survival after diagnosis of colorectal cancer. Gut. 2011;60(4):491–8.
    • (2011) Gut , vol.60 , Issue.4 , pp. 491-498
    • Coghill, A.E.1    Newcomb, P.A.2    Campbell, P.T.3    Burnett-Hartman, A.N.4    Adams, S.V.5    Poole, E.M.6
  • 32
    • 34247347310 scopus 로고    scopus 로고
    • Influence of regular aspirin use on survival for patients with stage III colon cancer: findings from intergroup trial CALGB 89803
    • Fuchs CS, Meyerhardt JA, Heseltine DL, Niedzwiecki D, Hollis D, Chan AT, et al. Influence of regular aspirin use on survival for patients with stage III colon cancer: findings from intergroup trial CALGB 89803. J Clin Oncol (Meeting Abstracts). 2005;23(16):Suppl 3530.
    • (2005) J Clin Oncol (Meeting Abstracts) , vol.23 , Issue.16 , pp. Suppl 3530
    • Fuchs, C.S.1    Meyerhardt, J.A.2    Heseltine, D.L.3    Niedzwiecki, D.4    Hollis, D.5    Chan, A.T.6
  • 33
    • 84885183806 scopus 로고    scopus 로고
    • Low-dose aspirin use and cancer characteristics: a population-based cohort study
    • PID: 23887604, COI: 1:CAS:528:DC%2BC3sXhsFyntbbK
    • Jonsson F, Yin L, Lundholm C, Smedby KE, Czene K, Pawitan Y. Low-dose aspirin use and cancer characteristics: a population-based cohort study. Br J Cancer. 2013;109(7):1921–5.
    • (2013) Br J Cancer , vol.109 , Issue.7 , pp. 1921-1925
    • Jonsson, F.1    Yin, L.2    Lundholm, C.3    Smedby, K.E.4    Czene, K.5    Pawitan, Y.6
  • 34
    • 84874938572 scopus 로고    scopus 로고
    • Use of aspirin post-diagnosis in a cohort of patients with colorectal cancer and its association with all-cause and colorectal cancer specific mortality
    • PID: 23182687, COI: 1:CAS:528:DC%2BC38XhslSmu7fE
    • McCowan C, Munro AJ, Donnan PT, Steele RJ. Use of aspirin post-diagnosis in a cohort of patients with colorectal cancer and its association with all-cause and colorectal cancer specific mortality. Eur J Cancer. 2013;49(5):1049–57.
    • (2013) Eur J Cancer , vol.49 , Issue.5 , pp. 1049-1057
    • McCowan, C.1    Munro, A.J.2    Donnan, P.T.3    Steele, R.J.4
  • 35
    • 78649854163 scopus 로고    scopus 로고
    • Effect of aspirin and NSAIDs on risk and survival from colorectal cancer
    • PID: 20844293, COI: 1:CAS:528:DC%2BC3MXpvFei
    • Din FV, Theodoratou E, Farrington SM, Tenesa A, Barnetson RA, Cetnarskyj R, et al. Effect of aspirin and NSAIDs on risk and survival from colorectal cancer. Gut. 2010;59(12):1670–9.
    • (2010) Gut , vol.59 , Issue.12 , pp. 1670-1679
    • Din, F.V.1    Theodoratou, E.2    Farrington, S.M.3    Tenesa, A.4    Barnetson, R.A.5    Cetnarskyj, R.6
  • 37
    • 84867897314 scopus 로고    scopus 로고
    • Aspirin and other non-steroidal anti-inflammatory drug use and colorectal cancer survival: a cohort study
    • PID: 23011483, COI: 1:CAS:528:DC%2BC38XhsFOntLnE
    • Walker AJ, Grainge MJ, Card TR. Aspirin and other non-steroidal anti-inflammatory drug use and colorectal cancer survival: a cohort study. Br J Cancer. 2012;107(9):1602–7.
    • (2012) Br J Cancer , vol.107 , Issue.9 , pp. 1602-1607
    • Walker, A.J.1    Grainge, M.J.2    Card, T.R.3
  • 38
    • 73149089476 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs: effects on mortality after colorectal cancer diagnosis
    • PID: 19827153
    • Zell JA, Ziogas A, Bernstein L, Clarke CA, Deapen D, Largent JA, et al. Nonsteroidal anti-inflammatory drugs: effects on mortality after colorectal cancer diagnosis. Cancer. 2009;115(24):5662–71.
    • (2009) Cancer , vol.115 , Issue.24 , pp. 5662-5671
    • Zell, J.A.1    Ziogas, A.2    Bernstein, L.3    Clarke, C.A.4    Deapen, D.5    Largent, J.A.6
  • 39
    • 84902266776 scopus 로고    scopus 로고
    • Aspirin in gastrointestinal oncology: new data on an old friend
    • PID: 24840525, COI: 1:CAS:528:DC%2BC2cXpsVeksr8%3D, Summary of evidence leading to the Add-Aspirin trial with description of trial protocol of aspirin at 100 or 300 mg vs. placebo in adjuvant treatment of CRC
    • Langley RE, Rothwell PM. Aspirin in gastrointestinal oncology: new data on an old friend. Curr Opin Oncol. 2014;26(4):441–7. Summary of evidence leading to the Add-Aspirin trial with description of trial protocol of aspirin at 100 or 300 mg vs. placebo in adjuvant treatment of CRC.
    • (2014) Curr Opin Oncol , vol.26 , Issue.4 , pp. 441-447
    • Langley, R.E.1    Rothwell, P.M.2
  • 40
    • 84902189509 scopus 로고    scopus 로고
    • Discovery of colorectal cancer PIK3CA mutation as potential predictive biomarker: power and promise of molecular pathological epidemiology
    • PID: 23792451, COI: 1:CAS:528:DC%2BC3sXpvVylsL8%3D
    • Ogino S, Lochhead P, Giovannucci E, Meyerhardt JA, Fuchs CS, Chan AT. Discovery of colorectal cancer PIK3CA mutation as potential predictive biomarker: power and promise of molecular pathological epidemiology. Oncogene. 2014;33:2949–55.
    • (2014) Oncogene , vol.33 , pp. 2949-2955
    • Ogino, S.1    Lochhead, P.2    Giovannucci, E.3    Meyerhardt, J.A.4    Fuchs, C.S.5    Chan, A.T.6
  • 41
    • 65849268320 scopus 로고    scopus 로고
    • Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials
    • COI: 1:CAS:528:DC%2BD1MXmsFyhsro%3D
    • Antithrombotic Trialists Collaboration. Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials. Lancet. 2009;373(9678):1849–60.
    • (2009) Lancet , vol.373 , Issue.9678 , pp. 1849-1860
    • Antithrombotic Trialists Collaboration1
  • 42
    • 84871623952 scopus 로고    scopus 로고
    • Biological markers: potential biomarker for aspirin use in colorectal cancer therapy
    • PID: 23207797, COI: 1:CAS:528:DC%2BC38XhvV2gt7fO
    • Langley RE, Rothwell PM. Biological markers: potential biomarker for aspirin use in colorectal cancer therapy. Nat Rev Clin Oncol. 2013;10(1):8–10.
    • (2013) Nat Rev Clin Oncol , vol.10 , Issue.1 , pp. 8-10
    • Langley, R.E.1    Rothwell, P.M.2
  • 43
    • 84867817838 scopus 로고    scopus 로고
    • Aspirin use, tumor PIK3CA mutation, and colorectal-cancer survival
    • PID: 23094721, COI: 1:CAS:528:DC%2BC38Xhs1Whsr3K, Observational data demonstrating reduction in cancer-specific death associated with low-dose aspirin use post diagnosis, restricted to those participants with PIK3CA mutation
    • Liao X, Lochhead P, Nishihara R, Morikawa T, Kuchiba A, Yamauchi M, et al. Aspirin use, tumor PIK3CA mutation, and colorectal-cancer survival. N Engl J Med. 2012;367(17):1596–606. Observational data demonstrating reduction in cancer-specific death associated with low-dose aspirin use post diagnosis, restricted to those participants with PIK3CA mutation.
    • (2012) N Engl J Med , vol.367 , Issue.17 , pp. 1596-1606
    • Liao, X.1    Lochhead, P.2    Nishihara, R.3    Morikawa, T.4    Kuchiba, A.5    Yamauchi, M.6
  • 44
    • 84879395305 scopus 로고    scopus 로고
    • Aspirin use and risk of colorectal cancer according to BRAF mutation status
    • PID: 23800934, COI: 1:CAS:528:DC%2BC3sXhtFOgs7fL
    • Nishihara R, Lochhead P, Kuchiba A, Jung S, Yamauchi M, Liao X, et al. Aspirin use and risk of colorectal cancer according to BRAF mutation status. JAMA. 2013;309(24):2563–71.
    • (2013) JAMA , vol.309 , Issue.24 , pp. 2563-2571
    • Nishihara, R.1    Lochhead, P.2    Kuchiba, A.3    Jung, S.4    Yamauchi, M.5    Liao, X.6
  • 46
    • 84892843686 scopus 로고    scopus 로고
    • Evaluation of PIK3CA mutation as a predictor of benefit from nonsteroidal anti-inflammatory drug therapy in colorectal cancer
    • PID: 24062397, COI: 1:CAS:528:DC%2BC3sXhvF2kur7J, Molecular analysis of cohort of patients from the VICTOR trial demonstrating correlation between PIK3CA mutation and improved survival with aspirin use after CRC diagnosis
    • Domingo E, Church DN, Sieber O, Ramamoorthy R, Yanagisawa Y, Johnstone E, et al. Evaluation of PIK3CA mutation as a predictor of benefit from nonsteroidal anti-inflammatory drug therapy in colorectal cancer. J Clin Oncol. 2013;31(34):4297–305. Molecular analysis of cohort of patients from the VICTOR trial demonstrating correlation between PIK3CA mutation and improved survival with aspirin use after CRC diagnosis.
    • (2013) J Clin Oncol , vol.31 , Issue.34 , pp. 4297-4305
    • Domingo, E.1    Church, D.N.2    Sieber, O.3    Ramamoorthy, R.4    Yanagisawa, Y.5    Johnstone, E.6
  • 47
    • 6944225725 scopus 로고    scopus 로고
    • COX-2 inhibition as a tool to treat and prevent colorectal cancer
    • COI: 1:STN:280:DC%2BD2crjtVChug%3D%3D
    • Tuynman JB, Peppelenbosch MP, Richel DJ. COX-2 inhibition as a tool to treat and prevent colorectal cancer. Crit Rev Oncol/Hematol. 2004;52(2):81–101.
    • (2004) Crit Rev Oncol/Hematol , vol.52 , Issue.2 , pp. 81-101
    • Tuynman, J.B.1    Peppelenbosch, M.P.2    Richel, D.J.3
  • 48
    • 33745238704 scopus 로고    scopus 로고
    • Cyclooxygenase-2 (COX-2)-independent anticarcinogenic effects of selective COX-2 inhibitors
    • PID: 16757698
    • Grösch S, Maier TJ, Schiffmann S, Geisslinger G. Cyclooxygenase-2 (COX-2)-independent anticarcinogenic effects of selective COX-2 inhibitors. J Natl Cancer Inst. 2006;98(11):736–47.
    • (2006) J Natl Cancer Inst , vol.98 , Issue.11 , pp. 736-747
    • Grösch, S.1    Maier, T.J.2    Schiffmann, S.3    Geisslinger, G.4
  • 49
    • 84870450832 scopus 로고    scopus 로고
    • Mechanisms of the antitumoural effects of aspirin in the gastrointestinal tract
    • PID: 23199511, COI: 1:CAS:528:DC%2BC38XhslGjsbnI
    • Bruno A, Dovizio M, Tacconelli S, Patrignani P. Mechanisms of the antitumoural effects of aspirin in the gastrointestinal tract. Best Pract Res Clin Gastroenterol. 2012;26(4):e1–e13.
    • (2012) Best Pract Res Clin Gastroenterol , vol.26 , Issue.4 , pp. e1-e13
    • Bruno, A.1    Dovizio, M.2    Tacconelli, S.3    Patrignani, P.4
  • 50
    • 0034921717 scopus 로고    scopus 로고
    • Colonic mucosal prostaglandin E2 and cyclooxygenase expression before and after low aspirin doses in subjects at high risk or at normal risk for colorectal cancer
    • PID: 11352853, COI: 1:CAS:528:DC%2BD3MXktlClu7w%3D
    • Krishnan K, Ruffin MT, Normolle D, Shureiqi I, Burney K, Bailey J, et al. Colonic mucosal prostaglandin E2 and cyclooxygenase expression before and after low aspirin doses in subjects at high risk or at normal risk for colorectal cancer. Cancer Epidemiol Biomarkers Prev. 2001;10(5):447–53.
    • (2001) Cancer Epidemiol Biomarkers Prev , vol.10 , Issue.5 , pp. 447-453
    • Krishnan, K.1    Ruffin, M.T.2    Normolle, D.3    Shureiqi, I.4    Burney, K.5    Bailey, J.6
  • 51
    • 0036227319 scopus 로고    scopus 로고
    • A dose-finding study of aspirin for chemoprevention utilizing rectal mucosal prostaglandin E(2) levels as a biomarker
    • PID: 11895877, COI: 1:CAS:528:DC%2BD38XivFyhsrY%3D
    • Sample D, Wargovich M, Fischer SM, Inamdar N, Schwartz P, Wang X, et al. A dose-finding study of aspirin for chemoprevention utilizing rectal mucosal prostaglandin E(2) levels as a biomarker. Cancer Epidemiol Biomarkers Prev. 2002;11(3):275–9.
    • (2002) Cancer Epidemiol Biomarkers Prev , vol.11 , Issue.3 , pp. 275-279
    • Sample, D.1    Wargovich, M.2    Fischer, S.M.3    Inamdar, N.4    Schwartz, P.5    Wang, X.6
  • 52
    • 84897978063 scopus 로고    scopus 로고
    • Expression of HLA class I antigen, aspirin use, and survival after a diagnosis of colon cancer
    • PID: 24687028, COI: 1:CAS:528:DC%2BC2cXhs1emurrP, Observational study demonstrating improved survival in participants using aspirin post-diagnosis with HLA class 1 antigen expression vs those missing HLA-1 expression. Does not show greater benefit of aspirin with PIK3CA mutation demonstrated by Domingo et al. and Liao et al
    • Reimers MS, Bastiaannet E, Langley RE, van Eijk R, van Vlierberghe RL, Lemmens VE, et al. Expression of HLA class I antigen, aspirin use, and survival after a diagnosis of colon cancer. JAMA Intern Med. 2014;174(5):732–9. Observational study demonstrating improved survival in participants using aspirin post-diagnosis with HLA class 1 antigen expression vs those missing HLA-1 expression. Does not show greater benefit of aspirin with PIK3CA mutation demonstrated by Domingo et al. and Liao et al.
    • (2014) JAMA Intern Med , vol.174 , Issue.5 , pp. 732-739
    • Reimers, M.S.1    Bastiaannet, E.2    Langley, R.E.3    van Eijk, R.4    van Vlierberghe, R.L.5    Lemmens, V.E.6
  • 53
    • 0033031331 scopus 로고    scopus 로고
    • COX-2 inhibitors
    • PID: 9929039, COI: 1:CAS:528:DyaK1MXhsF2lsrw%3D
    • Hawkey CJ. COX-2 inhibitors. Lancet. 1999;353(9149):307–14.
    • (1999) Lancet , vol.353 , Issue.9149 , pp. 307-314
    • Hawkey, C.J.1
  • 54
    • 34547148986 scopus 로고    scopus 로고
    • Rofecoxib and cardiovascular adverse events in adjuvant treatment of colorectal cancer
    • PID: 17652651, COI: 1:CAS:528:DC%2BD2sXotFChtrg%3D
    • Kerr DJ, Dunn JA, Langman MJ, Smith JL, Midgley RS, Stanley A, et al. Rofecoxib and cardiovascular adverse events in adjuvant treatment of colorectal cancer. N Engl J Med. 2007;357(4):360–9.
    • (2007) N Engl J Med , vol.357 , Issue.4 , pp. 360-369
    • Kerr, D.J.1    Dunn, J.A.2    Langman, M.J.3    Smith, J.L.4    Midgley, R.S.5    Stanley, A.6
  • 55
    • 0033530260 scopus 로고    scopus 로고
    • The relationship between cyclooxygenase-2 expression and colorectal cancer
    • PID: 10517428, COI: 1:CAS:528:DyaK1MXmvVWhtbk%3D
    • Sheehan KM, Sheahan K, O’Donoghue DP, MacSweeney F, Conroy RM, Fitzgerald DJ, et al. The relationship between cyclooxygenase-2 expression and colorectal cancer. JAMA. 1999;282(13):1254–7.
    • (1999) JAMA , vol.282 , Issue.13 , pp. 1254-1257
    • Sheehan, K.M.1    Sheahan, K.2    O’Donoghue, D.P.3    MacSweeney, F.4    Conroy, R.M.5    Fitzgerald, D.J.6
  • 56
    • 84866156209 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression as a predictor of outcome in colorectal carcinoma
    • PID: 22553404, COI: 1:CAS:528:DC%2BC38XmvFSnsLs%3D
    • Al-Maghrabi J, Buhmeida A, Emam E, Syrjanen K, Sibiany A, Al-Qahtani M, et al. Cyclooxygenase-2 expression as a predictor of outcome in colorectal carcinoma. World J Gastroenterol. 2012;18(15):1793–9.
    • (2012) World J Gastroenterol , vol.18 , Issue.15 , pp. 1793-1799
    • Al-Maghrabi, J.1    Buhmeida, A.2    Emam, E.3    Syrjanen, K.4    Sibiany, A.5    Al-Qahtani, M.6
  • 57
    • 78049523725 scopus 로고    scopus 로고
    • Phase III randomized trial assessing rofecoxib in the adjuvant setting of colorectal cancer: final results of the VICTOR trial
    • PID: 20837956, COI: 1:CAS:528:DC%2BC3cXhsFaitL%2FE
    • Midgley RS, McConkey CC, Johnstone EC, Dunn JA, Smith JL, Grumett SA, et al. Phase III randomized trial assessing rofecoxib in the adjuvant setting of colorectal cancer: final results of the VICTOR trial. J Clin Oncol. 2010;28(30):4575–80.
    • (2010) J Clin Oncol , vol.28 , Issue.30 , pp. 4575-4580
    • Midgley, R.S.1    McConkey, C.C.2    Johnstone, E.C.3    Dunn, J.A.4    Smith, J.L.5    Grumett, S.A.6
  • 58
    • 48349099492 scopus 로고    scopus 로고
    • Celecoxib pre-treatment in human colorectal adenocarcinoma patients is associated with gene expression alterations suggestive of diminished cellular proliferation
    • PID: 18653328, COI: 1:CAS:528:DC%2BD1cXpt1Grtbg%3D
    • Auman JT, Church R, Lee S-Y, Watson MA, Fleshman JW, McLeod HL. Celecoxib pre-treatment in human colorectal adenocarcinoma patients is associated with gene expression alterations suggestive of diminished cellular proliferation. Eur J Cancer. 2008;44(12):1754–60.
    • (2008) Eur J Cancer , vol.44 , Issue.12 , pp. 1754-1760
    • Auman, J.T.1    Church, R.2    Lee, S.-Y.3    Watson, M.A.4    Fleshman, J.W.5    McLeod, H.L.6
  • 59
    • 34249673868 scopus 로고    scopus 로고
    • Aspirin and the risk of colorectal cancer in relation to the expression of COX-2
    • PID: 17522398, COI: 1:CAS:528:DC%2BD2sXlvVersr0%3D
    • Chan AT, Ogino S, Fuchs CS. Aspirin and the risk of colorectal cancer in relation to the expression of COX-2. N Engl J Med. 2007;356(21):2131–42.
    • (2007) N Engl J Med , vol.356 , Issue.21 , pp. 2131-2142
    • Chan, A.T.1    Ogino, S.2    Fuchs, C.S.3
  • 60
    • 84865675069 scopus 로고    scopus 로고
    • Association between COX-2 expression and effectiveness of COX-2 inhibitors in a phase II trial in patients with metastatic colorectal adenocarcinoma
    • PID: 22843946, COI: 1:CAS:528:DC%2BC38Xht1Kmu7vP
    • Almhanna K, El-Rayes B, Sethi S, Dyson G, Heilbrun L, Philip PA, et al. Association between COX-2 expression and effectiveness of COX-2 inhibitors in a phase II trial in patients with metastatic colorectal adenocarcinoma. Anticancer Res. 2012;32(8):3559–63.
    • (2012) Anticancer Res , vol.32 , Issue.8 , pp. 3559-3563
    • Almhanna, K.1    El-Rayes, B.2    Sethi, S.3    Dyson, G.4    Heilbrun, L.5    Philip, P.A.6
  • 62
    • 84892882699 scopus 로고    scopus 로고
    • Aspirin therapy for colorectal cancer with PIK3CA mutation: simply complex!
    • PID: 24166520, COI: 1:CAS:528:DC%2BC3sXhvF2kur%2FJ
    • Fuchs CS, Ogino S. Aspirin therapy for colorectal cancer with PIK3CA mutation: simply complex! J Clin Oncol. 2013;31(34):4358–61.
    • (2013) J Clin Oncol , vol.31 , Issue.34 , pp. 4358-4361
    • Fuchs, C.S.1    Ogino, S.2
  • 63
    • 84901036853 scopus 로고    scopus 로고
    • PIK3CA in colorectal cancer
    • PID: 24624362
    • Cathomas G. PIK3CA in colorectal cancer. Front Oncol. 2014;4:35.
    • (2014) Front Oncol , vol.4 , pp. 35
    • Cathomas, G.1
  • 65
    • 84855893130 scopus 로고    scopus 로고
    • Platelet-derived MHC class I confers a pseudonormal phenotype to cancer cells that subverts the antitumor reactivity of natural killer immune cells
    • PID: 22127925, COI: 1:CAS:528:DC%2BC38Xos1Kluw%3D%3D
    • Placke T, Orgel M, Schaller M, Jung G, Rammensee HG, Kopp HG, et al. Platelet-derived MHC class I confers a pseudonormal phenotype to cancer cells that subverts the antitumor reactivity of natural killer immune cells. Cancer Res. 2012;72(2):440–8.
    • (2012) Cancer Res , vol.72 , Issue.2 , pp. 440-448
    • Placke, T.1    Orgel, M.2    Schaller, M.3    Jung, G.4    Rammensee, H.G.5    Kopp, H.G.6
  • 66
    • 81255205399 scopus 로고    scopus 로고
    • Direct signaling between platelets and cancer cells induces an epithelial-mesenchymal-like transition and promotes metastasis
    • PID: 22094253, COI: 1:CAS:528:DC%2BC3MXhsFSktLnJ
    • Labelle M, Begum S, Hynes RO. Direct signaling between platelets and cancer cells induces an epithelial-mesenchymal-like transition and promotes metastasis. Cancer Cell. 2011;20(5):576–90.
    • (2011) Cancer Cell , vol.20 , Issue.5 , pp. 576-590
    • Labelle, M.1    Begum, S.2    Hynes, R.O.3
  • 67
    • 84899547782 scopus 로고    scopus 로고
    • Aspirin and the risk of colorectal cancer in relation to the expression of 15-hydroxyprostaglandin dehydrogenase (HPGD)
    • PID: 24760190
    • Fink SP, Yamauchi M, Nishihara R, Jung S, Kuchiba A, Wu K, et al. Aspirin and the risk of colorectal cancer in relation to the expression of 15-hydroxyprostaglandin dehydrogenase (HPGD). Sci Transl Med. 2014;6(233):233re2.
    • (2014) Sci Transl Med , vol.6 , Issue.233 , pp. 233re2
    • Fink, S.P.1    Yamauchi, M.2    Nishihara, R.3    Jung, S.4    Kuchiba, A.5    Wu, K.6
  • 68
    • 84898920630 scopus 로고    scopus 로고
    • A prospective study of macrophage inhibitory cytokine-1 (MIC-1/GDF15) and risk of colorectal cancer
    • PID: 24565956
    • Mehta RS, Song M, Bezawada N, Wu K, Garcia-Albeniz X, Morikawa T, et al. A prospective study of macrophage inhibitory cytokine-1 (MIC-1/GDF15) and risk of colorectal cancer. J Natl Cancer Inst. 2014;106(4):dju016.
    • (2014) J Natl Cancer Inst , vol.106 , Issue.4 , pp. dju016
    • Mehta, R.S.1    Song, M.2    Bezawada, N.3    Wu, K.4    Garcia-Albeniz, X.5    Morikawa, T.6
  • 69
    • 84891449924 scopus 로고    scopus 로고
    • Aspirin use, 8q24 single nucleotide polymorphism rs6983267, and colorectal cancer according to CTNNB1 alterations
    • PID: 24317174, COI: 1:CAS:528:DC%2BC2cXhs1yrsw%3D%3D
    • Nan H, Morikawa T, Suuriniemi M, Imamura Y, Werner L, Kuchiba A, et al. Aspirin use, 8q24 single nucleotide polymorphism rs6983267, and colorectal cancer according to CTNNB1 alterations. J Natl Cancer Inst. 2013;105(24):1852–61.
    • (2013) J Natl Cancer Inst , vol.105 , Issue.24 , pp. 1852-1861
    • Nan, H.1    Morikawa, T.2    Suuriniemi, M.3    Imamura, Y.4    Werner, L.5    Kuchiba, A.6
  • 70
    • 67249157211 scopus 로고    scopus 로고
    • 15-Hydroxyprostaglandin dehydrogenase inactivation as a mechanism of resistance to celecoxib chemoprevention of colon tumors
    • PID: 19470469, COI: 1:CAS:528:DC%2BD1MXot1CgurY%3D
    • Yan M, Myung SJ, Fink SP, Lawrence E, Lutterbaugh J, Yang P, et al. 15-Hydroxyprostaglandin dehydrogenase inactivation as a mechanism of resistance to celecoxib chemoprevention of colon tumors. Proc Natl Acad Sci U S A. 2009;106(23):9409–13.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.23 , pp. 9409-9413
    • Yan, M.1    Myung, S.J.2    Fink, S.P.3    Lawrence, E.4    Lutterbaugh, J.5    Yang, P.6
  • 72
    • 84874372330 scopus 로고    scopus 로고
    • Dose-risk and duration-risk relationships between aspirin and colorectal cancer: a meta-analysis of published cohort studies
    • PID: 23451245, COI: 1:CAS:528:DC%2BC3sXjslyksb8%3D
    • Ye X, Fu J, Yang Y, Chen S. Dose-risk and duration-risk relationships between aspirin and colorectal cancer: a meta-analysis of published cohort studies. PLoS One. 2013;8(2):e57578.
    • (2013) PLoS One , vol.8 , Issue.2 , pp. e57578
    • Ye, X.1    Fu, J.2    Yang, Y.3    Chen, S.4


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