Low-dose aspirin use after diagnosis of colorectal cancer does not increase survival: A case-control analysis of a population-based cohort

Gastroenterology

Volumn 146, Issue 3, 2014, Pages

  Cardwell, Chris R ^a   Kunzmann, Andrew T ^a   Cantwell, Marie M ^a   Hughes, Carmel ^a   Baron, John A ^b   Powe, Des G ^c,d   Murray, Liam J ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c QUEEN S MEDICAL CENTRE   (United Kingdom)

^d NOTTINGHAM TRENT UNIVERSITY   (United Kingdom)

Author keywords

Antiplatelet Drugs; Colorectal Neoplasms; CPRD; Pharmacoepidemiology

Indexed keywords

ACETYLSALICYLIC ACID;

ADULT; AGED; ARTICLE; CANCER DIAGNOSIS; CANCER MORTALITY; CANCER SURVIVAL; COLORECTAL CANCER; CONTROLLED STUDY; DRUG USE; FEMALE; HUMAN; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; POPULATION BASED CASE CONTROL STUDY; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; SURVIVAL TIME; VERY ELDERLY;

ANTIPLATELET DRUGS; COLORECTAL NEOPLASMS; CPRD; PHARMACOEPIDEMIOLOGY;

ADULT; AGED; AGED, 80 AND OVER; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; CASE-CONTROL STUDIES; COHORT STUDIES; COLORECTAL NEOPLASMS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; MALE; MIDDLE AGED; NEOPLASM STAGING; RISK FACTORS; SURVIVAL RATE;

EID: 84894294540     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2013.11.005     Document Type: Article

References (33)

1. G.J. Gasic, T.B. Gasic, and C.C. Stewart Antimetastatic effects associated with platelet reduction Proc Natl Acad Sci USA 61 1968 46 52
2. N.M. Bambace, and C.E. Holmes The platelet contribution to cancer progression J Thromb Haemost 9 2011 237 249
3. L.J. Gay, and B. Felding-Habermann Contribution of platelets to tumour metastasis Nat Rev Cancer 11 2011 123 134
4. P.M. Rothwell, M. Wilson, and C.-E. Elwin et al. Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials Lancet 376 2010 1741 1750
5. P.M. Rothwell, M. Wilson, and J.F. Price et al. Effect of daily aspirin on risk of cancer metastasis: a study of incident cancers during randomised controlled trials Lancet 379 2012 1591 1601
6. A.T. Chan, S. Ogino, and C.S. Fuchs Aspirin use and survival after diagnosis of colorectal cancer JAMA 302 2009 649 658
7. X. Liao, P. Lochhead, and R. Nishihara et al. Aspirin use, tumor PIK3CA mutation, and colorectal-cancer survival N Engl J Med 367 2012 1596 1606
8. C. McCowan, A.J. Munro, and P.T. Donnan et al. Use of aspirin post-diagnosis in a cohort of patients with colorectal cancer and its association with all-cause and colorectal cancer specific mortality Eur J Cancer 49 2013 1049 1057
9. A.J. Walker, M.J. Grainge, and T.R. Card Aspirin and other non-steroidal anti-inflammatory drug use and colorectal cancer survival: a cohort study Br J Cancer 107 2012 1602 1607
10. E. Bastiaannet, K. Sampieri, and O.M. Dekkers et al. Use of aspirin postdiagnosis improves survival for colon cancer patients Br J Cancer 106 2012 1564 1570
11. M.S. Reimers, E. Bastiaannet, and M.P.P. van Herk-Sukel et al. Aspirin use after diagnosis improves survival in older adults with colon cancer: a retrospective cohort study J Am Geriatr Soc 60 2012 2232 2236
12. R. Boggon, T.P. van Staa, and M. Chapman et al. Cancer recording and mortality in the General Practice Research Database and linked cancer registries Pharmacoepidemiol Drug Saf 22 2013 168 175
13. H. Jick, S.S. Jick, and L.E. Derby Validation of information recorded on general practitioner based computerised data resource in the United Kingdom BMJ 302 1991 766 768
14. L. Azoulay, H. Yin, and K.B. Filion et al. The use of pioglitazone and the risk of bladder cancer in people with type 2 diabetes: nested case-control study BMJ 344 2012 e3645
15. R. Schade, F. Andersohn, and S. Suissa et al. Dopamine agonists and the risk of cardiac-valve regurgitation N Engl J Med 356 2007 29 38
16. L.E. Levesque, J.A. Hanley, and A. Kezouh et al. Problem of immortal time bias in cohort studies: example using statins for preventing progression of diabetes BMJ 340 2010 b5087-b5087
17. M. Etminan Pharmacoepidemiology II: the nested case-control study - a novel approach in pharmacoepidemiologic research Pharmacotherapy 24 2004 1105 1109
18. V. Essebag, R.W. Platt, and M. Abrahamowicz et al. Comparison of nested case-control and survival analysis methodologies for analysis of time-dependent exposure BMC Med Res Methodol 5 2005 5
19. N.F. Khan, R. Perera, and S. Harper et al. Adaptation and validation of the Charlson Index for Read/OXMIS coded databases BMC Fam Pract 11 2010 1
20. R.J. Dowling, P.J. Goodwin, and V. Stambolic Understanding the benefit of metformin use in cancer treatment BMC Med 9 2011 33
21. S. Sleijfer, A. van der Gaast, and A.S. Planting et al. The potential of statins as part of anti-cancer treatment Eur J Cancer 41 2005 516 522
22. E.F. Schisterman, S.R. Cole, and R.W. Platt Overadjustment bias and unnecessary adjustment in epidemiologic studies Epidemiology 20 2009 488 495
23. C.R. Weinberg Toward a clearer definition of confounding Am J Epidemiol 137 1993 1 8
24. D.G. Altman, and J.M. Bland Interaction revisited: the difference between two estimates BMJ 326 2003 219
25. H. Tamim, A.A.T. Monfared, and J. Lelorier Application of lag-time into exposure definitions to control for protopathic bias Pharmacoepidemiol Drug Saf 16 2007 250 258
26. U.K. Henschke, G.J. Luande, and J.D. Choppala Aspirin for reducing cancer metastases? J Natl Med Assoc 69 1977 581 584
27. A. Amirkhosravi, S.A. Mousa, and M. Amaya et al. Assessment of anti-metastatic effects of anticoagulant and antiplatelet agents using animal models of experimental lung metastasis Methods Mol Biol 663 2010 241 259
28. J.M. Evans, and T.M. MacDonald Misclassification and selection bias in case-control studies using an automated database Pharmacoepidemiol Drug Saf 6 1997 313 318
29. S.L. West, D.A. Savitz, and G. Koch et al. Recall accuracy for prescription medications: self-report compared with database information Am J Epidemiol 142 1995 1103 1112
30. Y.-X. Yang, S. Hennessy, and K. Propert et al. Chronic statin therapy and the risk of colorectal cancer Pharmacoepidemiol Drug Saf 17 2008 869 876
31. M.U. Yood, U.B. Campbell, and K.J. Rothman et al. Using prescription claims data for drugs available over-the-counter (OTC) Pharmacoepidemiol Drug Saf 16 2007 961 968
32. R. Ali, H.-C. Toh, and W.-K. Chia The utility of aspirin in Dukes C and high risk Dukes B colorectal cancer-the ASCOLT study: study protocol for a randomized controlled trial Trials 12 2011 261
33. Langley RE, Wilson RH, Ring A, et al. Evidence for the use of aspirin as a treatment for cancer and the planned Add-Aspirin trial. The First World Congress on Controversies in Gastroenterology, Berlin, Germany, 2013. Available at: http://www.comtecmed.com/cigi/2013/Abstracts-Text.aspx. Accessed November 1, 2013.