메뉴 건너뛰기




Volumn 5, Issue 1, 2015, Pages

Up-regulation of the Hippo pathway effector TAZ renders lung adenocarcinoma cells harboring EGFR-T790M mutation resistant to gefitinib

Author keywords

EGFR; EMT; Gefitinib; Lung adenocarcinoma; TAZ

Indexed keywords


EID: 85027944721     PISSN: None     EISSN: 20453701     Source Type: Journal    
DOI: 10.1186/2045-3701-5-7     Document Type: Article
Times cited : (44)

References (36)
  • 3
    • 61549108338 scopus 로고    scopus 로고
    • EGFR T790M mutation: a double role in lung cancer cell survival?
    • Suda K, Onozato R, Yatabe Y, Mitsudomi T: EGFR T790M mutation: a double role in lung cancer cell survival? J Thorac Oncol 2009,4(1):1-4. 10.1097/JTO.0b013e3181913c9f.
    • (2009) J Thorac Oncol , vol.4 , Issue.1 , pp. 1-4
    • Suda, K.1    Onozato, R.2    Yatabe, Y.3    Mitsudomi, T.4
  • 4
    • 84859418112 scopus 로고    scopus 로고
    • The EGFR T790M mutation in acquired resistance to an irreversible second-generation EGFR inhibitor
    • Kim Y, Ko J, Cui Z, Abolhoda A, Ahn JS, Ou SH, Ahn MJ, Park K: The EGFR T790M mutation in acquired resistance to an irreversible second-generation EGFR inhibitor. Mol Cancer Ther 2012,11(3):784-791. 10.1158/1535-7163.MCT-11-0750.
    • (2012) Mol Cancer Ther , vol.11 , Issue.3 , pp. 784-791
    • Kim, Y.1    Ko, J.2    Cui, Z.3    Abolhoda, A.4    Ahn, J.S.5    Ou, S.H.6    Ahn, M.J.7    Park, K.8
  • 5
    • 68849118748 scopus 로고    scopus 로고
    • Transcriptional coactivator with PDZ-binding motif is essential for normal alveolarization in mice
    • Mitani A, Nagase T, Fukuchi K, Aburatani H, Makita R, Kurihara H: Transcriptional coactivator with PDZ-binding motif is essential for normal alveolarization in mice. Am J Respir Crit Care Med 2009,180(4):326-338. 10.1164/rccm.200812-1827OC.
    • (2009) Am J Respir Crit Care Med , vol.180 , Issue.4 , pp. 326-338
    • Mitani, A.1    Nagase, T.2    Fukuchi, K.3    Aburatani, H.4    Makita, R.5    Kurihara, H.6
  • 7
    • 79960997489 scopus 로고    scopus 로고
    • The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal
    • Zhao B, Tumaneng K, Guan KL: The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal. Nat Cell Biol 2011,13(8):877-883. 10.1038/ncb2303.
    • (2011) Nat Cell Biol , vol.13 , Issue.8 , pp. 877-883
    • Zhao, B.1    Tumaneng, K.2    Guan, K.L.3
  • 10
    • 79955638768 scopus 로고    scopus 로고
    • TAZ is a novel oncogene in non-small cell lung cancer
    • Zhou Z, Hao Y, Liu N, Raptis L, Tsao MS, Yang X: TAZ is a novel oncogene in non-small cell lung cancer. Oncogene 2011,30(18):2181-2186. 10.1038/onc.2010.606.
    • (2011) Oncogene , vol.30 , Issue.18 , pp. 2181-2186
    • Zhou, Z.1    Hao, Y.2    Liu, N.3    Raptis, L.4    Tsao, M.S.5    Yang, X.6
  • 11
    • 84862122226 scopus 로고    scopus 로고
    • Prognostic significance of TAZ expression in resected non-small cell lung cancer
    • Xie M, Zhang L, He CS, Hou JH, Lin SX, Hu ZH, Xu F, Zhao HY: Prognostic significance of TAZ expression in resected non-small cell lung cancer. J Thorac Oncol 2012,7(5):799-807. 10.1097/JTO.0b013e318248240b.
    • (2012) J Thorac Oncol , vol.7 , Issue.5 , pp. 799-807
    • Xie, M.1    Zhang, L.2    He, C.S.3    Hou, J.H.4    Lin, S.X.5    Hu, Z.H.6    Xu, F.7    Zhao, H.Y.8
  • 16
    • 79953310106 scopus 로고    scopus 로고
    • Taxol resistance in breast cancer cells is mediated by the hippo pathway component TAZ and its downstream transcriptional targets Cyr61 and CTGF
    • Lai D, Ho KC, Hao Y, Yang X: Taxol resistance in breast cancer cells is mediated by the hippo pathway component TAZ and its downstream transcriptional targets Cyr61 and CTGF. Cancer Res 2011,71(7):2728-2738. 10.1158/0008-5472.CAN-10-2711.
    • (2011) Cancer Res , vol.71 , Issue.7 , pp. 2728-2738
    • Lai, D.1    Ho, K.C.2    Hao, Y.3    Yang, X.4
  • 17
    • 38449102122 scopus 로고    scopus 로고
    • A screen of shRNAs targeting tumor suppressor genes to identify factors involved in A549 paclitaxel sensitivity
    • Ji D, Deeds SL, Weinstein EJ: A screen of shRNAs targeting tumor suppressor genes to identify factors involved in A549 paclitaxel sensitivity. Oncol Rep 2007,18(6):1499-1505.
    • (2007) Oncol Rep , vol.18 , Issue.6 , pp. 1499-1505
    • Ji, D.1    Deeds, S.L.2    Weinstein, E.J.3
  • 20
    • 84876943442 scopus 로고    scopus 로고
    • YAP modifies cancer cell sensitivity to EGFR and survivin inhibitors and is negatively regulated by the non-receptor type protein tyrosine phosphatase 14
    • Huang JM, Nagatomo I, Suzuki E, Mizuno T, Kumagai T, Berezov A, Zhang H, Karlan B, Greene MI, Wang Q: YAP modifies cancer cell sensitivity to EGFR and survivin inhibitors and is negatively regulated by the non-receptor type protein tyrosine phosphatase 14. Oncogene 2013,32(17):2220-2229. 10.1038/onc.2012.231.
    • (2013) Oncogene , vol.32 , Issue.17 , pp. 2220-2229
    • Huang, J.M.1    Nagatomo, I.2    Suzuki, E.3    Mizuno, T.4    Kumagai, T.5    Berezov, A.6    Zhang, H.7    Karlan, B.8    Greene, M.I.9    Wang, Q.10
  • 23
    • 84872788552 scopus 로고    scopus 로고
    • Overexpression of Yes-associated protein confers doxorubicin resistance in hepatocellullar carcinoma
    • Huo X, Zhang Q, Liu AM, Tang C, Gong Y, Bian J, Luk JM, Xu Z, Chen J: Overexpression of Yes-associated protein confers doxorubicin resistance in hepatocellullar carcinoma. Oncol Rep 2013,29(2):840-846.
    • (2013) Oncol Rep , vol.29 , Issue.2 , pp. 840-846
    • Huo, X.1    Zhang, Q.2    Liu, A.M.3    Tang, C.4    Gong, Y.5    Bian, J.6    Luk, J.M.7    Xu, Z.8    Chen, J.9
  • 24
    • 84896400883 scopus 로고    scopus 로고
    • SIRT1 regulates YAP2-mediated cell proliferation and chemoresistance in hepatocellular carcinoma
    • Mao B, Hu F, Cheng J, Wang P, Xu M, Yuan F, Meng S, Wang Y, Yuan Z, Bi W: SIRT1 regulates YAP2-mediated cell proliferation and chemoresistance in hepatocellular carcinoma. Oncogene 2014,33(11):1468-1474. 10.1038/onc.2013.88.
    • (2014) Oncogene , vol.33 , Issue.11 , pp. 1468-1474
    • Mao, B.1    Hu, F.2    Cheng, J.3    Wang, P.4    Xu, M.5    Yuan, F.6    Meng, S.7    Wang, Y.8    Yuan, Z.9    Bi, W.10
  • 25
    • 84905987393 scopus 로고    scopus 로고
    • YAP-induced resistance of cancer cells to antitubulin drugs is modulated by a hippo-independent pathway
    • Zhao Y, Khanal P, Savage P, She YM, Cyr TD, Yang X: YAP-induced resistance of cancer cells to antitubulin drugs is modulated by a hippo-independent pathway. Cancer Res 2014,74(16):4493-4503. 10.1158/0008-5472.CAN-13-2712.
    • (2014) Cancer Res , vol.74 , Issue.16 , pp. 4493-4503
    • Zhao, Y.1    Khanal, P.2    Savage, P.3    She, Y.M.4    Cyr, T.D.5    Yang, X.6
  • 26
    • 84863692961 scopus 로고    scopus 로고
    • Tumour suppressor genes in chemotherapeutic drug response
    • Lai D, Visser-Grieve S, Yang X: Tumour suppressor genes in chemotherapeutic drug response. Biosci Rep 2012,32(4):361-374. 10.1042/BSR20110125.
    • (2012) Biosci Rep , vol.32 , Issue.4 , pp. 361-374
    • Lai, D.1    Visser-Grieve, S.2    Yang, X.3
  • 27
    • 79953121435 scopus 로고    scopus 로고
    • Clinical and molecular evidences of epithelial to mesenchymal transition in acquired resistance to EGFR-TKIs
    • Chung JH, Rho JK, Xu X, Lee JS, Yoon HI, Lee CT, Choi YJ, Kim HR, Kim CH, Lee JC: Clinical and molecular evidences of epithelial to mesenchymal transition in acquired resistance to EGFR-TKIs. Lung Cancer 2011,73(2):176-182. 10.1016/j.lungcan.2010.11.011.
    • (2011) Lung Cancer , vol.73 , Issue.2 , pp. 176-182
    • Chung, J.H.1    Rho, J.K.2    Xu, X.3    Lee, J.S.4    Yoon, H.I.5    Lee, C.T.6    Choi, Y.J.7    Kim, H.R.8    Kim, C.H.9    Lee, J.C.10
  • 28
    • 41149098966 scopus 로고    scopus 로고
    • TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway
    • Lei QY, Zhang H, Zhao B, Zha ZY, Bai F, Pei XH, Zhao S, Xiong Y, Guan KL: TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway. Mol Cell Biol 2008,28(7):2426-2436. 10.1128/MCB.01874-07.
    • (2008) Mol Cell Biol , vol.28 , Issue.7 , pp. 2426-2436
    • Lei, Q.Y.1    Zhang, H.2    Zhao, B.3    Zha, Z.Y.4    Bai, F.5    Pei, X.H.6    Zhao, S.7    Xiong, Y.8    Guan, K.L.9
  • 30
    • 67649412006 scopus 로고    scopus 로고
    • TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition
    • Zhang H, Liu CY, Zha ZY, Zhao B, Yao J, Zhao S, Xiong Y, Lei QY, Guan KL: TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition. J Biol Chem 2009,284(20):13355-13362. 10.1074/jbc.M900843200.
    • (2009) J Biol Chem , vol.284 , Issue.20 , pp. 13355-13362
    • Zhang, H.1    Liu, C.Y.2    Zha, Z.Y.3    Zhao, B.4    Yao, J.5    Zhao, S.6    Xiong, Y.7    Lei, Q.Y.8    Guan, K.L.9
  • 31
    • 84877858820 scopus 로고    scopus 로고
    • Emerging roles of TEAD transcription factors and its coactivators in cancers
    • Pobbati AV, Hong W: Emerging roles of TEAD transcription factors and its coactivators in cancers. Cancer Biol Ther 2013,14(5):390-398. 10.4161/cbt.23788.
    • (2013) Cancer Biol Ther , vol.14 , Issue.5 , pp. 390-398
    • Pobbati, A.V.1    Hong, W.2
  • 32
    • 65949093307 scopus 로고    scopus 로고
    • Connective tissue growth factor confers drug resistance in breast cancer through concomitant up-regulation of Bcl-xL and cIAP1
    • Wang MY, Chen PS, Prakash E, Hsu HC, Huang HY, Lin MT, Chang KJ, Kuo ML: Connective tissue growth factor confers drug resistance in breast cancer through concomitant up-regulation of Bcl-xL and cIAP1. Cancer Res 2009,69(8):3482-3491. 10.1158/0008-5472.CAN-08-2524.
    • (2009) Cancer Res , vol.69 , Issue.8 , pp. 3482-3491
    • Wang, M.Y.1    Chen, P.S.2    Prakash, E.3    Hsu, H.C.4    Huang, H.Y.5    Lin, M.T.6    Chang, K.J.7    Kuo, M.L.8
  • 33
    • 84894375063 scopus 로고    scopus 로고
    • CTGF increases drug resistance to paclitaxel by upregulating survivin expression in human osteosarcoma cells
    • Tsai HC, Huang CY, Su HL, Tang CH: CTGF increases drug resistance to paclitaxel by upregulating survivin expression in human osteosarcoma cells. Biochim Biophys Acta 2014,1843(5):846-854. 10.1016/j.bbamcr.2014.01.007.
    • (2014) Biochim Biophys Acta , vol.1843 , Issue.5 , pp. 846-854
    • Tsai, H.C.1    Huang, C.Y.2    Su, H.L.3    Tang, C.H.4
  • 36
    • 84884167635 scopus 로고    scopus 로고
    • The receptor AXL diversifies EGFR signaling and limits the response to EGFR-targeted inhibitors in triple-negative breast cancer cells
    • Meyer AS, Miller MA, Gertler FB, Lauffenburger DA: The receptor AXL diversifies EGFR signaling and limits the response to EGFR-targeted inhibitors in triple-negative breast cancer cells. Sci Signal 2013,6(287):ra66.
    • (2013) Sci Signal , vol.6 , Issue.287 , pp. ra66
    • Meyer, A.S.1    Miller, M.A.2    Gertler, F.B.3    Lauffenburger, D.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.