-
1
-
-
28444455958
-
Inherited susceptibility to lung cancer may be associated with the T790M drug resistance mutation in EGFR
-
Bell DW, Gore I, Okimoto RA, Godin-Heymann N, Sordella R, Mulloy R, Sharma SV, Brannigan BW, Mohapatra G, Settleman J, Haber DA: Inherited susceptibility to lung cancer may be associated with the T790M drug resistance mutation in EGFR. Nat Genet 2005,37(12):1315-1316. 10.1038/ng1671.
-
(2005)
Nat Genet
, vol.37
, Issue.12
, pp. 1315-1316
-
-
Bell, D.W.1
Gore, I.2
Okimoto, R.A.3
Godin-Heymann, N.4
Sordella, R.5
Mulloy, R.6
Sharma, S.V.7
Brannigan, B.W.8
Mohapatra, G.9
Settleman, J.10
Haber, D.A.11
-
2
-
-
84905498876
-
Tyrosine Phosphoproteomics Identifies Both Codrivers and Cotargeting Strategies for T790M-Related EGFR-TKI Resistance in Non-Small Cell Lung Cancer
-
Yoshida T, Zhang G, Smith MA, Lopez AS, Bai Y, Li J, Fang B, Koomen J, Rawal B, Fisher KJ, Chen AY, Kitano M, Morita Y, Yamaguchi H, Shibata K, Okabe T, Okamoto I, Nakagawa K, Haura EB: Tyrosine Phosphoproteomics Identifies Both Codrivers and Cotargeting Strategies for T790M-Related EGFR-TKI Resistance in Non-Small Cell Lung Cancer. Clin Cancer Res 2014,20(15):4059-4074. 10.1158/1078-0432.CCR-13-1559.
-
(2014)
Clin Cancer Res
, vol.20
, Issue.15
, pp. 4059-4074
-
-
Yoshida, T.1
Zhang, G.2
Smith, M.A.3
Lopez, A.S.4
Bai, Y.5
Li, J.6
Fang, B.7
Koomen, J.8
Rawal, B.9
Fisher, K.J.10
Chen, A.Y.11
Kitano, M.12
Morita, Y.13
Yamaguchi, H.14
Shibata, K.15
Okabe, T.16
Okamoto, I.17
Nakagawa, K.18
Haura, E.B.19
-
3
-
-
61549108338
-
EGFR T790M mutation: a double role in lung cancer cell survival?
-
Suda K, Onozato R, Yatabe Y, Mitsudomi T: EGFR T790M mutation: a double role in lung cancer cell survival? J Thorac Oncol 2009,4(1):1-4. 10.1097/JTO.0b013e3181913c9f.
-
(2009)
J Thorac Oncol
, vol.4
, Issue.1
, pp. 1-4
-
-
Suda, K.1
Onozato, R.2
Yatabe, Y.3
Mitsudomi, T.4
-
4
-
-
84859418112
-
The EGFR T790M mutation in acquired resistance to an irreversible second-generation EGFR inhibitor
-
Kim Y, Ko J, Cui Z, Abolhoda A, Ahn JS, Ou SH, Ahn MJ, Park K: The EGFR T790M mutation in acquired resistance to an irreversible second-generation EGFR inhibitor. Mol Cancer Ther 2012,11(3):784-791. 10.1158/1535-7163.MCT-11-0750.
-
(2012)
Mol Cancer Ther
, vol.11
, Issue.3
, pp. 784-791
-
-
Kim, Y.1
Ko, J.2
Cui, Z.3
Abolhoda, A.4
Ahn, J.S.5
Ou, S.H.6
Ahn, M.J.7
Park, K.8
-
5
-
-
68849118748
-
Transcriptional coactivator with PDZ-binding motif is essential for normal alveolarization in mice
-
Mitani A, Nagase T, Fukuchi K, Aburatani H, Makita R, Kurihara H: Transcriptional coactivator with PDZ-binding motif is essential for normal alveolarization in mice. Am J Respir Crit Care Med 2009,180(4):326-338. 10.1164/rccm.200812-1827OC.
-
(2009)
Am J Respir Crit Care Med
, vol.180
, Issue.4
, pp. 326-338
-
-
Mitani, A.1
Nagase, T.2
Fukuchi, K.3
Aburatani, H.4
Makita, R.5
Kurihara, H.6
-
6
-
-
23644431709
-
TAZ, a transcriptional modulator of mesenchymal stem cell differentiation
-
Hong JH, Hwang ES, McManus MT, Amsterdam A, Tian Y, Kalmukova R, Mueller E, Benjamin T, Spiegelman BM, Sharp PA, Hopkins N, Yaffe MB: TAZ, a transcriptional modulator of mesenchymal stem cell differentiation. Science 2005,309(5737):1074-1078. 10.1126/science.1110955.
-
(2005)
Science
, vol.309
, Issue.5737
, pp. 1074-1078
-
-
Hong, J.H.1
Hwang, E.S.2
McManus, M.T.3
Amsterdam, A.4
Tian, Y.5
Kalmukova, R.6
Mueller, E.7
Benjamin, T.8
Spiegelman, B.M.9
Sharp, P.A.10
Hopkins, N.11
Yaffe, M.B.12
-
7
-
-
79960997489
-
The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal
-
Zhao B, Tumaneng K, Guan KL: The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal. Nat Cell Biol 2011,13(8):877-883. 10.1038/ncb2303.
-
(2011)
Nat Cell Biol
, vol.13
, Issue.8
, pp. 877-883
-
-
Zhao, B.1
Tumaneng, K.2
Guan, K.L.3
-
8
-
-
84886943235
-
Role of TAZ as mediator of Wnt signaling
-
Azzolin L, Zanconato F, Bresolin S, Forcato M, Basso G, Bicciato S, Cordenonsi M, Piccolo S: Role of TAZ as mediator of Wnt signaling. Cell 2012,151(7):1443-1456. 10.1016/j.cell.2012.11.027.
-
(2012)
Cell
, vol.151
, Issue.7
, pp. 1443-1456
-
-
Azzolin, L.1
Zanconato, F.2
Bresolin, S.3
Forcato, M.4
Basso, G.5
Bicciato, S.6
Cordenonsi, M.7
Piccolo, S.8
-
9
-
-
79958284636
-
Role of YAP/TAZ in mechanotransduction
-
Dupont S, Morsut L, Aragona M, Enzo E, Giulitti S, Cordenonsi M, Zanconato F, Le Digabel J, Forcato M, Bicciato S, Elvassore N, Piccolo S: Role of YAP/TAZ in mechanotransduction. Nature 2011,474(7350):179-183. 10.1038/nature10137.
-
(2011)
Nature
, vol.474
, Issue.7350
, pp. 179-183
-
-
Dupont, S.1
Morsut, L.2
Aragona, M.3
Enzo, E.4
Giulitti, S.5
Cordenonsi, M.6
Zanconato, F.7
Le Digabel, J.8
Forcato, M.9
Bicciato, S.10
Elvassore, N.11
Piccolo, S.12
-
10
-
-
79955638768
-
TAZ is a novel oncogene in non-small cell lung cancer
-
Zhou Z, Hao Y, Liu N, Raptis L, Tsao MS, Yang X: TAZ is a novel oncogene in non-small cell lung cancer. Oncogene 2011,30(18):2181-2186. 10.1038/onc.2010.606.
-
(2011)
Oncogene
, vol.30
, Issue.18
, pp. 2181-2186
-
-
Zhou, Z.1
Hao, Y.2
Liu, N.3
Raptis, L.4
Tsao, M.S.5
Yang, X.6
-
11
-
-
84862122226
-
Prognostic significance of TAZ expression in resected non-small cell lung cancer
-
Xie M, Zhang L, He CS, Hou JH, Lin SX, Hu ZH, Xu F, Zhao HY: Prognostic significance of TAZ expression in resected non-small cell lung cancer. J Thorac Oncol 2012,7(5):799-807. 10.1097/JTO.0b013e318248240b.
-
(2012)
J Thorac Oncol
, vol.7
, Issue.5
, pp. 799-807
-
-
Xie, M.1
Zhang, L.2
He, C.S.3
Hou, J.H.4
Lin, S.X.5
Hu, Z.H.6
Xu, F.7
Zhao, H.Y.8
-
12
-
-
84929332040
-
An Integrative Analysis of the Tumorigenic Role of TAZ in Human Non-Small Cell Lung Cancer
-
Noguchi S, Saito A, Horie M, Mikami Y, Suzuki HI, Morishita Y, Ohshima M, Abiko Y, Mattsson JS, König H, Lohr M, Edlund K, Botling J, Micke P, Nagase T: An Integrative Analysis of the Tumorigenic Role of TAZ in Human Non-Small Cell Lung Cancer. Clin Cancer Res 2014,20(17):4660-4672. 10.1158/1078-0432.CCR-13-3328.
-
(2014)
Clin Cancer Res
, vol.20
, Issue.17
, pp. 4660-4672
-
-
Noguchi, S.1
Saito, A.2
Horie, M.3
Mikami, Y.4
Suzuki, H.I.5
Morishita, Y.6
Ohshima, M.7
Abiko, Y.8
Mattsson, J.S.9
König, H.10
Lohr, M.11
Edlund, K.12
Botling, J.13
Micke, P.14
Nagase, T.15
-
13
-
-
84864541239
-
TAZ induces growth factor-independent proliferation through activation of EGFR ligand amphiregulin
-
Yang N, Morrison CD, Liu P, Miecznikowski J, Bshara W, Han S, Zhu Q, Omilian AR, Li X, Zhang J: TAZ induces growth factor-independent proliferation through activation of EGFR ligand amphiregulin. Cell Cycle 2012,11(15):2922-2930. 10.4161/cc.21386.
-
(2012)
Cell Cycle
, vol.11
, Issue.15
, pp. 2922-2930
-
-
Yang, N.1
Morrison, C.D.2
Liu, P.3
Miecznikowski, J.4
Bshara, W.5
Han, S.6
Zhu, Q.7
Omilian, A.R.8
Li, X.9
Zhang, J.10
-
14
-
-
40049099220
-
The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP
-
Yun CH, Mengwasser KE, Toms AV, Woo MS, Greulich H, Wong KK, Meyerson M, Eck MJ: The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP. Proc Natl Acad Sci U S A 2008,105(6):2070-2075. 10.1073/pnas.0709662105.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.6
, pp. 2070-2075
-
-
Yun, C.H.1
Mengwasser, K.E.2
Toms, A.V.3
Woo, M.S.4
Greulich, H.5
Wong, K.K.6
Meyerson, M.7
Eck, M.J.8
-
15
-
-
84898640056
-
Tumor-propagating cells and Yap/Taz activity contribute to lung tumor progression and metastasis
-
Lau AN, Curtis SJ, Fillmore CM, Rowbotham SP, Mohseni M, Wagner DE, Beede AM, Montoro DT, Sinkevicius KW, Walton ZE, Barrios J, Weiss DJ, Camargo FD, Wong KK, Kim CF: Tumor-propagating cells and Yap/Taz activity contribute to lung tumor progression and metastasis. EMBO J 2014,33(5):468-481. 10.1002/embj.201386082.
-
(2014)
EMBO J
, vol.33
, Issue.5
, pp. 468-481
-
-
Lau, A.N.1
Curtis, S.J.2
Fillmore, C.M.3
Rowbotham, S.P.4
Mohseni, M.5
Wagner, D.E.6
Beede, A.M.7
Montoro, D.T.8
Sinkevicius, K.W.9
Walton, Z.E.10
Barrios, J.11
Weiss, D.J.12
Camargo, F.D.13
Wong, K.K.14
Kim, C.F.15
-
16
-
-
79953310106
-
Taxol resistance in breast cancer cells is mediated by the hippo pathway component TAZ and its downstream transcriptional targets Cyr61 and CTGF
-
Lai D, Ho KC, Hao Y, Yang X: Taxol resistance in breast cancer cells is mediated by the hippo pathway component TAZ and its downstream transcriptional targets Cyr61 and CTGF. Cancer Res 2011,71(7):2728-2738. 10.1158/0008-5472.CAN-10-2711.
-
(2011)
Cancer Res
, vol.71
, Issue.7
, pp. 2728-2738
-
-
Lai, D.1
Ho, K.C.2
Hao, Y.3
Yang, X.4
-
17
-
-
38449102122
-
A screen of shRNAs targeting tumor suppressor genes to identify factors involved in A549 paclitaxel sensitivity
-
Ji D, Deeds SL, Weinstein EJ: A screen of shRNAs targeting tumor suppressor genes to identify factors involved in A549 paclitaxel sensitivity. Oncol Rep 2007,18(6):1499-1505.
-
(2007)
Oncol Rep
, vol.18
, Issue.6
, pp. 1499-1505
-
-
Ji, D.1
Deeds, S.L.2
Weinstein, E.J.3
-
18
-
-
54049121368
-
Yes-associated protein (YAP) functions as a tumor suppressor in breast
-
Yuan M, Tomlinson V, Lara R, Holliday D, Chelala C, Harada T, Gangeswaran R, Manson-Bishop C, Smith P, Danovi SA, Pardo O, Crook T, Mein CA, Lemoine NR, Jones LJ, Basu S: Yes-associated protein (YAP) functions as a tumor suppressor in breast. Cell Death Differ 2008,15(11):1752-1759. 10.1038/cdd.2008.108.
-
(2008)
Cell Death Differ
, vol.15
, Issue.11
, pp. 1752-1759
-
-
Yuan, M.1
Tomlinson, V.2
Lara, R.3
Holliday, D.4
Chelala, C.5
Harada, T.6
Gangeswaran, R.7
Manson-Bishop, C.8
Smith, P.9
Danovi, S.A.10
Pardo, O.11
Crook, T.12
Mein, C.A.13
Lemoine, N.R.14
Jones, L.J.15
Basu, S.16
-
19
-
-
78449290378
-
Hippo pathway effector Yap is an ovarian cancer oncogene
-
Hall CA, Wang R, Miao J, Oliva E, Shen X, Wheeler T, Hilsenbeck SG, Orsulic S, Goode S: Hippo pathway effector Yap is an ovarian cancer oncogene. Cancer Res 2010,70(21):8517-8525. 10.1158/0008-5472.CAN-10-1242.
-
(2010)
Cancer Res
, vol.70
, Issue.21
, pp. 8517-8525
-
-
Hall, C.A.1
Wang, R.2
Miao, J.3
Oliva, E.4
Shen, X.5
Wheeler, T.6
Hilsenbeck, S.G.7
Orsulic, S.8
Goode, S.9
-
20
-
-
84876943442
-
YAP modifies cancer cell sensitivity to EGFR and survivin inhibitors and is negatively regulated by the non-receptor type protein tyrosine phosphatase 14
-
Huang JM, Nagatomo I, Suzuki E, Mizuno T, Kumagai T, Berezov A, Zhang H, Karlan B, Greene MI, Wang Q: YAP modifies cancer cell sensitivity to EGFR and survivin inhibitors and is negatively regulated by the non-receptor type protein tyrosine phosphatase 14. Oncogene 2013,32(17):2220-2229. 10.1038/onc.2012.231.
-
(2013)
Oncogene
, vol.32
, Issue.17
, pp. 2220-2229
-
-
Huang, J.M.1
Nagatomo, I.2
Suzuki, E.3
Mizuno, T.4
Kumagai, T.5
Berezov, A.6
Zhang, H.7
Karlan, B.8
Greene, M.I.9
Wang, Q.10
-
21
-
-
84896713066
-
Colon cancer cells escape 5FU chemotherapy-induced cell death by entering stemness and quiescence associated with the c-Yes/YAP axis
-
Touil Y, Igoudjil W, Corvaisier M, Dessein AF, Vandomme J, Monté D, Stechly L, Skrypek N, Langlois C, Grard G, Millet G, Leteurtre E, Dumont P, Truant S, Pruvot FR, Hebbar M, Fan F, Ellis LM, Formstecher P, Van Seuningen I, Gespach C, Polakowska R, Huet G: Colon cancer cells escape 5FU chemotherapy-induced cell death by entering stemness and quiescence associated with the c-Yes/YAP axis. Clin Cancer Res 2014,20(4):837-846. 10.1158/1078-0432.CCR-13-1854.
-
(2014)
Clin Cancer Res
, vol.20
, Issue.4
, pp. 837-846
-
-
Touil, Y.1
Igoudjil, W.2
Corvaisier, M.3
Dessein, A.F.4
Vandomme, J.5
Monté, D.6
Stechly, L.7
Skrypek, N.8
Langlois, C.9
Grard, G.10
Millet, G.11
Leteurtre, E.12
Dumont, P.13
Truant, S.14
Pruvot, F.R.15
Hebbar, M.16
Fan, F.17
Ellis, L.M.18
Formstecher, P.19
Van Seuningen, I.20
Gespach, C.21
Polakowska, R.22
Huet, G.23
more..
-
22
-
-
84879139034
-
Yes-associated protein (YAP) increases chemosensitivity of hepatocellular carcinoma cells by modulation of p53
-
Bai N, Zhang C, Liang N, Zhang Z, Chang A, Yin J, Li Z, Luo N, Tan X, Luo N, Luo Y, Xiang R, Li X, Reisfeld RA, Stupack D, Lv D, Liu C: Yes-associated protein (YAP) increases chemosensitivity of hepatocellular carcinoma cells by modulation of p53. Cancer Biol Ther 2013,14(6):511-520. 10.4161/cbt.24345.
-
(2013)
Cancer Biol Ther
, vol.14
, Issue.6
, pp. 511-520
-
-
Bai, N.1
Zhang, C.2
Liang, N.3
Zhang, Z.4
Chang, A.5
Yin, J.6
Li, Z.7
Luo, N.8
Tan, X.9
Luo, N.10
Luo, Y.11
Xiang, R.12
Li, X.13
Reisfeld, R.A.14
Stupack, D.15
Lv, D.16
Liu, C.17
-
23
-
-
84872788552
-
Overexpression of Yes-associated protein confers doxorubicin resistance in hepatocellullar carcinoma
-
Huo X, Zhang Q, Liu AM, Tang C, Gong Y, Bian J, Luk JM, Xu Z, Chen J: Overexpression of Yes-associated protein confers doxorubicin resistance in hepatocellullar carcinoma. Oncol Rep 2013,29(2):840-846.
-
(2013)
Oncol Rep
, vol.29
, Issue.2
, pp. 840-846
-
-
Huo, X.1
Zhang, Q.2
Liu, A.M.3
Tang, C.4
Gong, Y.5
Bian, J.6
Luk, J.M.7
Xu, Z.8
Chen, J.9
-
24
-
-
84896400883
-
SIRT1 regulates YAP2-mediated cell proliferation and chemoresistance in hepatocellular carcinoma
-
Mao B, Hu F, Cheng J, Wang P, Xu M, Yuan F, Meng S, Wang Y, Yuan Z, Bi W: SIRT1 regulates YAP2-mediated cell proliferation and chemoresistance in hepatocellular carcinoma. Oncogene 2014,33(11):1468-1474. 10.1038/onc.2013.88.
-
(2014)
Oncogene
, vol.33
, Issue.11
, pp. 1468-1474
-
-
Mao, B.1
Hu, F.2
Cheng, J.3
Wang, P.4
Xu, M.5
Yuan, F.6
Meng, S.7
Wang, Y.8
Yuan, Z.9
Bi, W.10
-
25
-
-
84905987393
-
YAP-induced resistance of cancer cells to antitubulin drugs is modulated by a hippo-independent pathway
-
Zhao Y, Khanal P, Savage P, She YM, Cyr TD, Yang X: YAP-induced resistance of cancer cells to antitubulin drugs is modulated by a hippo-independent pathway. Cancer Res 2014,74(16):4493-4503. 10.1158/0008-5472.CAN-13-2712.
-
(2014)
Cancer Res
, vol.74
, Issue.16
, pp. 4493-4503
-
-
Zhao, Y.1
Khanal, P.2
Savage, P.3
She, Y.M.4
Cyr, T.D.5
Yang, X.6
-
26
-
-
84863692961
-
Tumour suppressor genes in chemotherapeutic drug response
-
Lai D, Visser-Grieve S, Yang X: Tumour suppressor genes in chemotherapeutic drug response. Biosci Rep 2012,32(4):361-374. 10.1042/BSR20110125.
-
(2012)
Biosci Rep
, vol.32
, Issue.4
, pp. 361-374
-
-
Lai, D.1
Visser-Grieve, S.2
Yang, X.3
-
27
-
-
79953121435
-
Clinical and molecular evidences of epithelial to mesenchymal transition in acquired resistance to EGFR-TKIs
-
Chung JH, Rho JK, Xu X, Lee JS, Yoon HI, Lee CT, Choi YJ, Kim HR, Kim CH, Lee JC: Clinical and molecular evidences of epithelial to mesenchymal transition in acquired resistance to EGFR-TKIs. Lung Cancer 2011,73(2):176-182. 10.1016/j.lungcan.2010.11.011.
-
(2011)
Lung Cancer
, vol.73
, Issue.2
, pp. 176-182
-
-
Chung, J.H.1
Rho, J.K.2
Xu, X.3
Lee, J.S.4
Yoon, H.I.5
Lee, C.T.6
Choi, Y.J.7
Kim, H.R.8
Kim, C.H.9
Lee, J.C.10
-
28
-
-
41149098966
-
TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway
-
Lei QY, Zhang H, Zhao B, Zha ZY, Bai F, Pei XH, Zhao S, Xiong Y, Guan KL: TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway. Mol Cell Biol 2008,28(7):2426-2436. 10.1128/MCB.01874-07.
-
(2008)
Mol Cell Biol
, vol.28
, Issue.7
, pp. 2426-2436
-
-
Lei, Q.Y.1
Zhang, H.2
Zhao, B.3
Zha, Z.Y.4
Bai, F.5
Pei, X.H.6
Zhao, S.7
Xiong, Y.8
Guan, K.L.9
-
29
-
-
81055140859
-
The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells
-
Cordenonsi M, Zanconato F, Azzolin L, Forcato M, Rosato A, Frasson C, Inui M, Montagner M, Parenti AR, Poletti A, Daidone MG, Dupont S, Basso G, Bicciato S, Piccolo S: The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells. Cell 2011,147(4):759-772. 10.1016/j.cell.2011.09.048.
-
(2011)
Cell
, vol.147
, Issue.4
, pp. 759-772
-
-
Cordenonsi, M.1
Zanconato, F.2
Azzolin, L.3
Forcato, M.4
Rosato, A.5
Frasson, C.6
Inui, M.7
Montagner, M.8
Parenti, A.R.9
Poletti, A.10
Daidone, M.G.11
Dupont, S.12
Basso, G.13
Bicciato, S.14
Piccolo, S.15
-
30
-
-
67649412006
-
TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition
-
Zhang H, Liu CY, Zha ZY, Zhao B, Yao J, Zhao S, Xiong Y, Lei QY, Guan KL: TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition. J Biol Chem 2009,284(20):13355-13362. 10.1074/jbc.M900843200.
-
(2009)
J Biol Chem
, vol.284
, Issue.20
, pp. 13355-13362
-
-
Zhang, H.1
Liu, C.Y.2
Zha, Z.Y.3
Zhao, B.4
Yao, J.5
Zhao, S.6
Xiong, Y.7
Lei, Q.Y.8
Guan, K.L.9
-
31
-
-
84877858820
-
Emerging roles of TEAD transcription factors and its coactivators in cancers
-
Pobbati AV, Hong W: Emerging roles of TEAD transcription factors and its coactivators in cancers. Cancer Biol Ther 2013,14(5):390-398. 10.4161/cbt.23788.
-
(2013)
Cancer Biol Ther
, vol.14
, Issue.5
, pp. 390-398
-
-
Pobbati, A.V.1
Hong, W.2
-
32
-
-
65949093307
-
Connective tissue growth factor confers drug resistance in breast cancer through concomitant up-regulation of Bcl-xL and cIAP1
-
Wang MY, Chen PS, Prakash E, Hsu HC, Huang HY, Lin MT, Chang KJ, Kuo ML: Connective tissue growth factor confers drug resistance in breast cancer through concomitant up-regulation of Bcl-xL and cIAP1. Cancer Res 2009,69(8):3482-3491. 10.1158/0008-5472.CAN-08-2524.
-
(2009)
Cancer Res
, vol.69
, Issue.8
, pp. 3482-3491
-
-
Wang, M.Y.1
Chen, P.S.2
Prakash, E.3
Hsu, H.C.4
Huang, H.Y.5
Lin, M.T.6
Chang, K.J.7
Kuo, M.L.8
-
33
-
-
84894375063
-
CTGF increases drug resistance to paclitaxel by upregulating survivin expression in human osteosarcoma cells
-
Tsai HC, Huang CY, Su HL, Tang CH: CTGF increases drug resistance to paclitaxel by upregulating survivin expression in human osteosarcoma cells. Biochim Biophys Acta 2014,1843(5):846-854. 10.1016/j.bbamcr.2014.01.007.
-
(2014)
Biochim Biophys Acta
, vol.1843
, Issue.5
, pp. 846-854
-
-
Tsai, H.C.1
Huang, C.Y.2
Su, H.L.3
Tang, C.H.4
-
34
-
-
84871998076
-
An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance
-
Byers LA, Diao L, Wang J, Saintigny P, Girard L, Peyton M, Shen L, Fan Y, Giri U, Tumula PK, Nilsson MB, Gudikote J, Tran H, Cardnell RJ, Bearss DJ, Warner SL, Foulks JM, Kanner SB, Gandhi V, Krett N, Rosen ST, Kim ES, Herbst RS, Blumenschein GR, Lee JJ, Lippman SM, Ang KK, Mills GB, Hong WK, Weinstein JN, Wistuba II, Coombes KR, Minna JD, Heymach JV: An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance. Clin Cancer Res 2013,19(1):279-290. 10.1158/1078-0432.CCR-12-1558.
-
(2013)
Clin Cancer Res
, vol.19
, Issue.1
, pp. 279-290
-
-
Byers, L.A.1
Diao, L.2
Wang, J.3
Saintigny, P.4
Girard, L.5
Peyton, M.6
Shen, L.7
Fan, Y.8
Giri, U.9
Tumula, P.K.10
Nilsson, M.B.11
Gudikote, J.12
Tran, H.13
Cardnell, R.J.14
Bearss, D.J.15
Warner, S.L.16
Foulks, J.M.17
Kanner, S.B.18
Gandhi, V.19
Krett, N.20
Rosen, S.T.21
Kim, E.S.22
Herbst, R.S.23
Blumenschein, G.R.24
Lee, J.J.25
Lippman, S.M.26
Ang, K.K.27
Mills, G.B.28
Hong, W.K.29
Weinstein, J.N.30
Wistuba, I.I.31
Coombes, K.R.32
Minna, J.D.33
Heymach, J.V.34
more..
-
35
-
-
84864402225
-
Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer
-
Zhang Z, Lee JC, Lin L, Olivas V, Au V, LaFramboise T, Abdel-Rahman M, Wang X, Levine AD, Rho JK, Choi YJ, Choi CM, Kim SW, Jang SJ, Park YS, Kim WS, Lee DH, Lee JS, Miller VA, Arcila M, Ladanyi M, Moonsamy P, Sawyers C, Boggon TJ, Ma PC, Costa C, Taron M, Rosell R, Halmos B, Bivona TG: Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer. Nat Genet 2012,44(8):852-860. 10.1038/ng.2330
-
(2012)
Nat Genet
, vol.44
, Issue.8
, pp. 852-860
-
-
Zhang, Z.1
Lee, J.C.2
Lin, L.3
Olivas, V.4
Au, V.5
LaFramboise, T.6
Abdel-Rahman, M.7
Wang, X.8
Levine, A.D.9
Rho, J.K.10
Choi, Y.J.11
Choi, C.M.12
Kim, S.W.13
Jang, S.J.14
Park, Y.S.15
Kim, W.S.16
Lee, D.H.17
Lee, J.S.18
Miller, V.A.19
Arcila, M.20
Ladanyi, M.21
Moonsamy, P.22
Sawyers, C.23
Boggon, T.J.24
Ma, P.C.25
Costa, C.26
Taron, M.27
Rosell, R.28
Halmos, B.29
Bivona, T.G.30
more..
-
36
-
-
84884167635
-
The receptor AXL diversifies EGFR signaling and limits the response to EGFR-targeted inhibitors in triple-negative breast cancer cells
-
Meyer AS, Miller MA, Gertler FB, Lauffenburger DA: The receptor AXL diversifies EGFR signaling and limits the response to EGFR-targeted inhibitors in triple-negative breast cancer cells. Sci Signal 2013,6(287):ra66.
-
(2013)
Sci Signal
, vol.6
, Issue.287
, pp. ra66
-
-
Meyer, A.S.1
Miller, M.A.2
Gertler, F.B.3
Lauffenburger, D.A.4
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