Transcriptional coactivator with PDZ-binding motif is essential for normal alveolarization in mice

American Journal of Respiratory and Critical Care Medicine

Volumn 180, Issue 4, 2009, Pages 326-338

  Mitani, Akihisa ^a   Nagase, Takahide ^a   Fukuchi, Kazunori ^b   Aburatani, Hiroyuki ^c   Makita, Ryosuke ^a   Kurihara, Hiroki ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b Kyorin Pharmaceutical Company   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

Connective tissue growth factor; Emphysema; Lung development; Pulmonary fibrosis; Taz deficient mice

Indexed keywords

BLEOMYCIN; CONNECTIVE TISSUE GROWTH FACTOR; PDZ PROTEIN; SMAD PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTIONAL COACTIVATOR WITH PDZ BINDING MOTIF; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; DNA RESPONSIVE ELEMENT; DOWN REGULATION; EMBRYO; EMBRYO DEVELOPMENT; GENE EXPRESSION REGULATION; GENE FUNCTION; HETEROZYGOSITY; HOMOZYGOTE; LUNG DEVELOPMENT; LUNG EMPHYSEMA; LUNG FIBROSIS; MICROARRAY ANALYSIS; MOUSE; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; UPREGULATION; WILD TYPE;

ANIMALS; BLEOMYCIN; CELL DIFFERENTIATION; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; HOMOZYGOTE; KIDNEY; LUNG; LUNG COMPLIANCE; MICE; MICE, KNOCKOUT; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PEPTIDES; PHENOTYPE; PULMONARY ALVEOLI; PULMONARY EMPHYSEMA; PULMONARY FIBROSIS; REFERENCE VALUES; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ACTIVATION; UP-REGULATION;

EID: 68849118748     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.200812-1827OC     Document Type: Article

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