Identification of phenolic compounds in aqueous and ethanolic rooibos extracts (Aspalathus linearis) by HPLC-ESI-MS (TOF/IT)

Analytical and Bioanalytical Chemistry

Volumn 400, Issue 10, 2011, Pages 3643-3654

  Iswaldi, Ihsan ^a,b   Arráez Román, David ^a,b   Rodríguez Medina, Inmaculada ^a,b   Beltrán Debón, Raúl ^c   Joven, Jorge ^c   Segura Carretero, Antonio ^a,b   Fernández Gutiérrez, Alberto ^a,b  

^a UNIVERSITY OF GRANADA   (Spain)

^b Research and Development Functional Food Center (CIDAF)   (Spain)

^c HOSPITAL UNIVERSITARI SANT JOAN DE REUS   (Spain)

Author keywords

High performance liquid chromatography (HPLC); Mass spectrometry (MS); Polyphenols; Rooibos tea

Indexed keywords

ATOMIC EMISSION SPECTROSCOPY; CHROMATOGRAPHY; ELECTROSPRAY IONIZATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INDUCTIVELY COUPLED PLASMA; IONIZATION OF LIQUIDS; LASER INDUCED BREAKDOWN SPECTROSCOPY; MASS SPECTROMETRY; PHENOLS; POLYPHENOLIC COMPOUNDS; SPECTROMETRY;

ASPALATHUS LINEARIS; BENEFICIAL EFFECTS; ETHANOLIC EXTRACTS; FRAGMENTATION PATTERNS; PHENOLIC COMPOUNDS; POLYPHENOLS; ROOIBOS TEAS; SERUM TRIGLYCERIDE;

LIQUID CHROMATOGRAPHY;

ASPALATHUS LINEARIS; CAMELLIA SINENSIS;

EID: 85027944002     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-011-4998-z     Document Type: Article

References (41)

1. TP Kondratyuk JM Pezzuto 2004 Natural product polyphenols of relevance to human health Pharm Biol 42 46 63 10.3109/13880200490893519 1:CAS:528: DC%2BD2MXit1KisQ%3D%3D (Pubitemid 40093209)
2. RJ Nijveldt E van Nood DEC van Hoorn PG Boelens K van Norren PAM van Leeuwen 2001 Flavonoids: a review of probable mechanisms of action and potential applications Am J Clin Nutr 74 418 425 1:CAS:528:DC%2BD3MXnt1Cksro%3D (Pubitemid 32880250)
3. DL McKay JB Blumberg 2007 A review of the bioactivity of South African herbal teas: rooibos (Aspalathus linearis) and honeybush (Cyclopia intermedia) Phytother Res 21 1 16 10.1002/ptr.1992 1:CAS:528:DC%2BD2sXhvFyls7s%3D (Pubitemid 46173902)
4. L Erickson 2003 Rooibos tea: research into antioxidant and antimutagenic properties J Am Bot Counc 59 34 45
5. A von Gadow E Joubert CF Hansmann 1997 Comparison of the antioxidant activity of aspalathin with that of other plant phenols of rooibos tea (Aspalathus linearis), α-tocopherol, BHT, and BHA J Agric Food Chem 45 632 638 10.1021/jf960281n (Pubitemid 127483680)
6. A von Gadow E Joubert CF Hansmann 1997 Comparison of the antioxidant activity of rooibos tea (Aspalathus linearis) with green, oolong and black tea Food Chem 60 73 77 10.1016/S0308-8146(96)00312-3 (Pubitemid 27230486)
7. E Joubert 1996 HPLC quantification of the dihydrochalcones, aspalathin and nothofagin in rooibos tea (Aspalathus linearis) as affected by processing Food Chem 55 403 411 10.1016/0308-8146(95)00166-2 1:CAS:528:DyaK28XisFeru70%3D (Pubitemid 26119656)
8. BH Koeppen JB Smit DG Roux 1962 The flavone C-glycosides and flavonol O-glycosides of Aspalathus acuminatus (rooibos tea) Biochem J 83 507 511 1:CAS:528:DyaF38XksFWjtLs%3D
9. BH Koeppen 1965 C-Glycosylflavonoids. The chemistry of orientin and iso-orientin Biochem J 97 444 448 1:CAS:528:DyaF2MXkvV2hsL0%3D
10. BH Koeppen DG Roux 1965 Aspalathin: a novel C-glycosylflavonoid from Aspalathus linearis Tetrahedron Lett 6 3497 3503 10.1016/S0040-4039(01)89333-3
11. C Rabe JA Steenkamp E Joubert JFW Burger D Ferreira 1994 Phenolic metabolites from rooibos tea (Aspalathus linearis) Phytochem 35 1559 1565 10.1016/S0031-9422(00)86894-6 1:CAS:528:DyaK2cXktVOrsrY%3D (Pubitemid 2067932)
12. N Krafczyk MA Glomb 2008 Characterization of phenolic compounds in rooibos tea J Agric Food Chem 56 3368 3376 10.1021/jf703701n 1:CAS:528:DC%2BD1cXksFWisrk%3D (Pubitemid 351746069)
13. A Kawano H Nakamura S Hata M Minakawa Y Miura K Yagasaki 2009 Hypoglycemic effect of aspalathin, a rooibos tea component from Aspalathus linearis, in type 2 diabetic model db/db mice Phytomed 16 437 443 10.1016/j.phymed.2008.11.009 1:CAS:528:DC%2BD1MXmtVymtbg%3D
14. 4-induced liver damage in rats Physiol Res 52 461 466 1:STN:280:DC%2BD3szms1Kgug%3D%3D (Pubitemid 37039911)
15. O Ulicna O Vancova P Bozek J Cársky K Sebeková P Boor M Nakano M Greksák 2006 Rooibos tea (Aspalathus linearis) partially prevents oxidative stress in streptozotocin-induced diabetic rats Physiol Res 55 157 164 1:STN:280:DC%2BD283isFOhsw%3D%3D
16. H Baba Y Ohtsuka H Haruna T Lee S Nagata M Maeda Y Yamashiro T Shimizu 2009 Studies of anti-inflammatory effects of rooibos tea in rats Pediatr Int 51 700 704 10.1111/j.1442-200X.2009.02835.x
17. R Beltrán-Debón A Rull F Rodríguez-Sanabria I Iswaldi M Herranz-López G Aragonés J Camps C Alonso-Villaverde JA Menéndez V Micol A Segura-Carretero J Joven 2011 Continuous administration of polyphenols from aqueous rooibos (Aspalathus linearis) extract ameliorates dietary-induced metabolic disturbances in hyperlipidemic mice Phymed 10.1016/j.phymed.2010.11.008
18. S Fu D Arráez-Roman A Segura-Carretero JA Menéndez MP Menéndez-Gutiérrez V Micol A Fernández-Gutiérrez 2010 Qualitative screening of phenolic compounds in olive leaf extracts by hyphenated liquid chromatography and preliminary evaluation of cytotoxic activity against human breast cancer cells Anal Bioanal Chem 397 643 654 10.1007/s00216-010-3604-0 1:CAS:528:DC%2BC3cXjtlGntbo%3D
19. VL Singleton JA Rossi 1965 Colorimetry of total phenolics with phosphomolybdic-phosphotungstic acid reagents Am J Enol Vitic 16 144 158 1:CAS:528:DyaF28Xit1yhuw%3D%3D
20. P Waridel J-L Wolfender K Ndjoko KR Hobby HJ Major K Hostettmann 2001 Evaluation of quadrupole time-of-flight tandem mass spectrometry and ion-trap multiple-stage mass spectrometry for the differentiation of C-glycosidic flavonoid isomers J Chromatogr A 926 29 41 10.1016/S0021-9673(01)00806-8 1:CAS:528:DC%2BD3MXlslCitLY%3D (Pubitemid 32739004)
21. T Mishio T Honma T Iwashina 2006 Yellow flavonoids in Centaurea ruthenica as flower pigments Biochem Syst Ecol 34 180 184 10.1016/j.bse.2005.07.019 1:CAS:528:DC%2BD28Xls1Cisg%3D%3D (Pubitemid 43117222)
22. L Zhou J Kang L Fan X Ma H Zhao J Han B Wang D Guo 2008 Simultaneous analysis of coumarins and secoiridoids in Cortex Fraxini by high-performance liquid chromatography-diode array detection-electrospray ionization tandem mass spectrometry J Pharm Biomed Anal 47 39 46 10.1016/j.jpba.2007.12.009 1:CAS:528:DC%2BD1cXks1GmtLc%3D
23. K Kazuma T Takahashi K Sato H Takeuchi T Matsumoto T Okuno 2000 Quinochalcones and flavonoids from fresh florets in different cultivars of Carthamus tinctorius L. Biosci Biotechnol Biochem 64 1588 1599 10.1271/bbb.64.1588 1:CAS:528:DC%2BD3cXmsVahur4%3D
24. N Shimamura T Miyase K Umehara T Warashina S Fujii 2006 Phytoestrogens from Aspalathus linearis Biol Pharm Bull 29 1271 1274 10.1248/bpb.29.1271 1:CAS:528:DC%2BD28XnslOmu7c%3D (Pubitemid 43845498)
25. L Rastrelli P Saturnino O Schettino A Dini 1995 Studies on the constituents of Chenopodium pallidicaule (Cañihua) seeds. Isolation and characterization of two new flavonol glycosides J Agric Food Chem 43 2020 2024 10.1021/jf00056a012 1:CAS:528:DyaK2MXntFChu7c%3D
26. C Xie NC Veitch PJ Houghton MSJ Simmonds 2003 Flavone C-glycosides from Viola yedoensis Makino Chem Pharm Bull 51 1204 1207 10.1248/cpb.51.1204 1:CAS:528:DC%2BD3sXotlGku7Y%3D (Pubitemid 41663084)
27. MBC Gallo WC Rocha US Da Cunha FA Diogo FC da Silva PC Vieira 2006 Bioactivity of extracts and isolated compounds from Vitex polygama (Verbenaceae) and Siphoneugena densiflora (Myrtaceae) against Spodoptera frugiperda (Lepidoptera: Noctuidae) Pest Manag Sci 62 1072 1081 10.1002/ps.1278 1:CAS:528:DC%2BD28XhtFGqtr3O (Pubitemid 44620824)
28. P Champagnat A Heitz A Carnat D Fraisse AP Carnat JL Lamaison 2008 Flavonoids from Vetiveria zizanioides and Vetiveria nigritana (Poaceae) Biochem Syst Ecol 36 68 70 10.1016/j.bse.2007.05.015 1:CAS:528:DC%2BD2sXhtlGjs7nP (Pubitemid 350122871)
29. X Li Z Xiong X Ying L Cui W Zhu FA Li 2006 A rapid ultra-performance liquid chromatography-electrospray ionization tandem mass spectrometric method for the qualitative and quantitative analysis of the constituents of the flower of Trollius ledibouri Reichb Anal Chim Acta 580 170 180 10.1016/j.aca.2006.07. 069 1:CAS:528:DC%2BD28XhtFertbnK (Pubitemid 44633847)
30. SL de Moraes JC Tomaz NP Lopes 2007 Liquid chromatography-tandem mass spectrometric method for determination of the anti-inflammatory compound vicenin-2 in the leaves of L. ericoides Mart. Biomed Chromatogr 21 925 930 10.1002/bmc.828 (Pubitemid 47272328)
31. L Bramati M Minoggio C Gardana P Simonetti P Mauri P Pietta 2002 Quantitative characterization of flavonoid compounds in rooibos tea (Aspalathus linearis) by LC-UV/DAD J Agric Food Chem 50 5513 5519 10.1021/jf025697h 1:CAS:528:DC%2BD38XmsFGlsL0%3D
32. CS Philbin SJ Schwartz 2007 Resolution of diastereomeric flavonoid (1S)-(-)-camphanic acid esters via reversed-phased HPLC Phytochem 68 1206 1211 10.1016/j.phytochem.2007.01.022 1:CAS:528:DC%2BD2sXjvFeitbs%3D (Pubitemid 46528454)
33. PW Snijman S Swanevelder E Joubert IR Green WCA Gelderblom 2007 The antimutagenic acitivity of the major flavonoids of rooibos (Aspalathus linearis): some dose-response effects on mutagen activation-flavonoid interactions Mutat Res 631 111 123 1:CAS:528:DC%2BD2sXmvVOnsLk%3D (Pubitemid 46929154)
34. S Kazuno M Yanagida N Shindo K Murayama 2005 Mass spectrometric identification and quantification of glycosyl flavonoids, including dihydrochalcones with neutral loss scan mode Anal Biochem 347 182 192 10.1016/j.ab.2005.09.020 1:CAS:528:DC%2BD2MXht1Ght77P (Pubitemid 41681804)
35. YL Ma QM Li H van Den Heuvel M Claeys 1997 Characterization of flavone and flavonol aglycones by collision-induced dissociation tandem mass spectrometry Rapid Commun Mass Spectrom 11 1357 1364 10.1002/(SICI)1097- 0231(199708)11:12<1357::AID-RCM983>3.0.CO;2-9 1:CAS:528:DyaK2sXlsFOjtbw%3D (Pubitemid 27358300)
36. N Fabre I Rustan E de Hoffmann J Quetin-Leclercq 2001 Determination of flavone, flavonol, and flavanone aglycones by negative ion liquid chromatography electrospray ion-trap mass spectrometry J Am Soc Mass Spectrom 12 707 715 10.1016/S1044-0305(01)00226-4 1:CAS:528:DC%2BD3MXktFGqsrk%3D (Pubitemid 34546585)
37. M Dueñas H Mingo-Chornet JJ Pérez-Alonso R Di Paola-Naranjo AM González-Paramás C Santos-Buelga 2008 Preparation of quercetin glucuronides and characterization by HPLC-DAD-ESI/MS Eur Food Res Technol 227 1069 1076 10.1007/s00217-008-0821-2
38. Ferreira D, Marais C, Steenkamp JA, Joubert E (1995) Rooibos tea as a likely health food supplement. In: Proceedings of the Recent Development of Technologies on Fundamental Foods for Health. Korean Society of Food Science and Technology, Seoul, Korea, pp 73-88
39. Z Kowalewski K Mrugasiewicz 1971 Flavonoid heterosides in Crataegus phenophyrum [Neue flavanon heteroside in Crataegus phenophyrum] Planta Med 19 311 331 10.1055/s-0028-1099647 1:CAS:528:DyaE3MXktlWgtro%3D
40. JA Ozga A Saeed W Wismer DM Reinecke 2007 Characterization of cyanidin- and quercetin-derived flavonoids and other phenolics in mature saskatoon fruits (Amelanchier alnifolia Nutt.) J Agric Food Chem 55 10414 10424 10.1021/jf072949b 1:CAS:528:DC%2BD2sXht12gs7fM
41. G Gattuso C Caristi C Gargiulli E Bellocco G Toscano U Leuzzi 2006 Flavonoid glycosides in bergamot juice (Citrus bergamia Risso) J Agric Food Chem 54 3929 3935 10.1021/jf060348z 1:CAS:528:DC%2BD28Xkt12msbw%3D (Pubitemid 44030573)