Lesion of the lateral parabrachial nucleus attenuates the anorectic effect of peripheral amylin and CCK

Brain Research

Volumn 1162, Issue 1, 2007, Pages 76-84

  Becskei, Csilla ^a   Grabler, Valérie ^a   Edwards, Gaylen L ^b   Riediger, Thomas ^a   Lutz, Thomas A ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY OF GEORGIA   (United States)

Author keywords

Area postrema; c Fos; Central amygdala; Food intake; Immunohistochemistry

Indexed keywords

AMYLIN; CHOLECYSTOKININ; PROTEIN C FOS;

AMYGDALOID NUCLEUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANOREXIA; ARTICLE; BRAIN STEM; CONTROLLED STUDY; GENE DISRUPTION; NONHUMAN; PARABRACHIAL NUCLEUS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SOLITARY TRACT NUCLEUS;

AMYLOID; ANALYSIS OF VARIANCE; ANIMALS; ANOREXIA; BEHAVIOR, ANIMAL; BRAIN STEM; CELL COUNT; CHOLECYSTOKININ; EATING; GENE EXPRESSION REGULATION; MALE; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, WISTAR;

ANIMALIA; RATTUS;

EID: 34447618969     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2007.06.016     Document Type: Article

References (37)

1. Banks W.A., Kastin A.J., Maness L.M., Huang W., and Jaspan J.B. Permeability of the blood-brain barrier to amylin. Life Sci. 57 (1995) 1993-2001
2. Barth S.W., Riediger T., Lutz T.A., and Rechkemmer G. Differential effects of amylin and salmon calcitonin on neuropeptide gene expression in the lateral hypothalamic area and the arcuate nucleus of the rat. Neurosci. Lett. 341 (2003) 131-134
3. Berk M.L., and Finkelstein J.A. Afferent projections to the preoptic area and hypothalamic regions in the rat brain. Neuroscience 6 (1981) 1601-1624
4. Bester H., Besson J.M., and Bernard J.F. Organization of efferent projections from the parabrachial area to the hypothalamus: a Phaseolus vulgaris-leucoagglutinin study in the rat. J. Comp. Neurol. 383 (1997) 245-281
5. Block C.H., Hoffman G., and Kapp B.S. Peptide-containing pathways from the parabrachial complex to the central nucleus of the amygdala. Peptides 10 (1989) 465-471
6. Crawley J.N., and Kiss J.Z. Paraventricular nucleus lesions abolish the inhibition of feeding induced by systemic cholecystokinin. Peptides 6 (1985) 927-935
7. Day H.E., McKnight A.T., Poat J.A., and Hughes J. Evidence that cholecystokinin induces immediate early gene expression in the brainstem, hypothalamus and amygdala of the rat by a CCKA receptor mechanism. Neuropharmacology 33 (1994) 719-727
8. Edwards G.L., and Ritter R.C. Lateral parabrachial lesions attenuate ingestive effects of area postrema lesions. Am. J. Physiol. 256 (1989) R306-R312
9. Edwards G.L., Ladenheim E.E., and Ritter R.C. Dorsomedial hindbrain participation in cholecystokinin-induced satiety. Am. J. Physiol. 251 (1986) R971-R977
10. Hermann G.E., and Rogers R.C. Convergence of vagal and gustatory afferent input within the parabrachial nucleus of the rat. J. Auton. Nerv. Syst. 13 (1985) 1-17
11. Li B.H., and Rowland N.E. Cholecystokinin and dexfenfluramine-induced anorexia compared using devazepide and c-Fos expression in the rat brain. Regul. Pept. 50 (1994) 223-233
12. Li B.H., and Rowland N.E. Effects of vagotomy on cholecystokinin- and dexfenfluramine-induced Fos-like immunoreactivity in the rat brain. Brain Res. Bull. 37 (1995) 589-593
13. Lutz T.A., Del Prete E., and Scharrer E. Reduction of food intake in rats by intraperitoneal injection of low doses of amylin. Physiol. Behav. 55 (1994) 891-895
14. Lutz T.A., Del Prete E., and Scharrer E. Subdiaphragmatic vagotomy does not influence the anorectic effect of amylin. Peptides 16 (1995) 457-462
15. Lutz T.A., Althaus J., Rossi R., and Scharrer E. Anorectic effect of amylin is not transmitted by capsaicin-sensitive nerve fibers. Am. J. Physiol. 274 (1998) R1777-R1782
16. Lutz T.A., Senn M., Althaus J., Del Prete E., Ehrensperger F., and Scharrer E. Lesion of the area postrema/nucleus of the solitary tract (AP/NTS) attenuates the anorectic effects of amylin and calcitonin gene-related peptide (CGRP) in rats. Peptides 19 (1998) 309-317
17. Lutz T.A., Mollet A., Rushing P.A., Riediger T., and Scharrer E. The anorectic effect of a chronic peripheral infusion of amylin is abolished in area postrema/nucleus of the solitary tract (AP/NTS) lesioned rats. Int. J. Obes. Relat. Metab. Disord. 25 (2001) 1005-1011
18. Mayne R.G., Armstrong W.E., Crowley W.R., and Bealer S.L. Cytoarchitectonic analysis of Fos-immunoreactivity in brainstem neurons following visceral stimuli in conscious rats. J. Neuroend. 10 (1998) 839-847
19. Mönnikes H., Lauer G., and Arnold R. Peripheral administration of cholecystokinin activates c-Fos expression in the locus coeruleus/subcoeruleus nucleus, dorsal vagal complex and paraventricular nucleus via capsaicin-sensitive vagal afferents and CCK-A receptors in the rat. Brain Res. 770 (1997) 277-288
20. Morley J.E., Flood J.F., Horowitz M., Morley P.M., and Walter M.J. Modulation of food intake by peripherally administered amylin. Am. J. Physiol.: Regul., Integr. Comp. Physiol. 267 (1994) R178-R184
21. Norgen R. Projections from the nucleus of the solitary tract in the rat. Neuroscience 3 (1978) 207-218
22. Passaro Jr. E., Debas H., Oldendorf W., and Yamada T. Rapid appearance of intraventricularly administered neuropeptides in the peripheral circulation. Brain Res. 241 (1982) 335-340
23. Paxinos G., and Watson C. The Rat Brain in Stereotaxic Coordinates. 4th ed. (1998), Academic, New York
24. Ricardo J.A., and Koh E.T. Anatomical evidence of direct projections from the nucleus of the solitary tract to the hypothalamus, amygdala, and other forebrain structures in the rat. Brain Res. 153 (1978) 1-26
25. Riediger T., Schmid H.A., Lutz T.A., and Simon E. Amylin potently activates AP neurons possibly via formation of the excitatory second messenger cGMP. Am. J. Physiol.: Regul., Integr. Comp. Physiol. 281 (2001) R1833-R1843
26. Riediger T., Zuend D., Becskei C., and Lutz T.A. The anorectic hormone amylin contributes to feeding-related changes of neuronal activity in key structures of the gut-brain axis. Am. J. Physiol.: Regul., Integr. Comp. Physiol. 286 (2004) R114-R122
27. Rinaman L., Hoffman G.E., Dohanics J., Le W.W., Stricker E.M., and Verbalis J.G. Cholecystokinin activates catecholaminergic neurons in the caudal medulla that innervate the paraventricular nucleus of the hypothalamus in rats. J. Comp. Neurol. 360 (1995) 246-256
28. Ritter R.C., Covasa M., and Matson C.A. Cholecystokinin: proofs and prospects for involvement in control of food intake and body weight. Neuropeptides 33 (1999) 387-399
29. Rowland N.E., and Richmond R.M. Area postrema and the anorectic actions of dexfenfluramine and amylin. Brain Res. 820 (1999) 86-91
30. Rowland N.E., Crews E.C., and Gentry R.M. Comparison of Fos induced in rat brain by GLP-1 and amylin. Regul. Pept. 71 (1997) 171-174
31. Sexton P.M., Paxinos G., Kenney M.A., Wookey P.J., and Beaumont K. In vitro autoradiographic localization of amylin binding sites in rat brain. Neuroscience 62 (1994) 553-567
32. Shapiro R.E., and Miselis R.R. The central neural connections of the area postrema of the rat. J. Comp. Neurol. 234 (1985) 344-364
33. Shapiro R.E., and Miselis R.R. The central organization of the vagus nerve innervating the stomach of the rat. J. Comp. Neurol. 238 (1985) 473-488
34. Trifunovic R., and Reilly S. Medial versus lateral parabrachial nucleus lesions in the rat: effects on cholecystokinin- and d-fenfluramine-induced anorexia. Brain Res. 894 (2001) 288-296
35. Trifunovic R., and Reilly S. Excitotoxic lesions of the lateral parabrachial nucleus do not prevent cholecystokinin-induced suppression of milk intake in rats. Neurosci. Lett. 348 (2003) 109-112
36. 125I] Bolton Hunter-rat amylin binding sites in the rat brain. J. Pharmacol. Exp. Ther. 270 (1994) 779-787
37. Voshart K., and Van Der Kooy D. The organization of the efferent projections of the parabrachial nucleus to the forebrain in the rat: a retrograde fluorescent double-labeling study. Brain Res. 212 (1981) 271-286