Polymicrobial acute respiratory infections in a hospital-based pediatric population

Pediatric Infectious Disease Journal

Volumn 32, Issue 5, 2013, Pages 460-466

  Chorazy, Margaret L ^a   Lebeck, Mark G ^a   McCarthy, Troy A ^b   Richter, Sandra S ^c   Torner, James C ^a   Gray, Gregory C ^d  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c LERNER RESEARCH INSTITUTE   (United States)

^d UNIVERSITY OF FLORIDA   (United States)

Author keywords

Acute respiratory infection; Coinfection; Epidemiology; Polymicrobial infection

Indexed keywords

ADENOVIRUS INFECTION; ARTICLE; BOCAVIRUS; BOCAVIRUS INFECTION; CHILD; CROSS-SECTIONAL STUDY; FEMALE; HUMAN; HUMAN ADENOVIRUS; HUMAN METAPNEUMOVIRUS INFECTION; INFANT; INFLUENZA; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MALE; METAPNEUMOVIRUS; MIXED INFECTION; PARAINFLUENZA VIRUS INFECTION; PEDIATRICS; PRESCHOOL CHILD; PREVALENCE; PRIORITY JOURNAL; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; RESPIRATORY SYNCYTIAL VIRUS INFECTION; RESPIRATORY TRACT DISEASE; RESPIRATORY TRACT INFECTION; RETROSPECTIVE STUDY; RHINOVIRUS; RHINOVIRUS INFECTION; RISK FACTOR;

ACUTE DISEASE; BACTERIAL INFECTIONS; CHILD; CHILD, PRESCHOOL; COINFECTION; CROSS-SECTIONAL STUDIES; FEMALE; HOSPITALS, PEDIATRIC; HUMANS; INFANT; MALE; RESPIRATORY TRACT INFECTIONS; RETROSPECTIVE STUDIES; RISK FACTORS; VIRUS DISEASES;

EID: 85027935955     PISSN: 08913668     EISSN: 15320987     Source Type: Journal    
DOI: 10.1097/INF.0b013e31828683ce     Document Type: Article

References (37)

1. Mahony JB. Detection of respiratory viruses by molecular methods. Clin Microbiol Rev. 2008;21:716-747.
2. Sly PD, Jones CM. Viral co-detection in infants hospitalized with respiratory disease: is it important to detect? J Pediatr (Rio J). 2011;87:277-280.
3. Bellau-Pujol S, Vabret A, Legrand L, et al. Development of three multiplex RT-PCR assays for the detection of 12 respiratory RNA viruses. J Virol Methods. 2005;126:53-63.
4. Bharaj P, Sullender WM, Kabra SK, et al. Respiratory viral infections detected by multiplex PCR among pediatric patients with lower respiratory tract infections seen at an urban hospital in Delhi from 2005 to 2007. Virol J. 2009;6:89.
5. Bonzel L, Tenenbaum T, Schroten H, et al. Frequent detection of viral coin-fection in children hospitalized with acute respiratory tract infection using a real-time polymerase chain reaction. Pediatr Infect Dis J. 2008;27:589-594.
6. Brouard J, Freymuth F, Vabret A, et al. Viral co-infections in immunocompetent infants with bronchiolitis: prospective epidemiologic study. Arch Pediatr. 2000;7(suppl 3):531S-5S.
7. Choi EH, Lee HJ, Kim SJ, et al. The association of newly identified respiratory viruses with lower respiratory tract infections in Korean children, 2000-2005. Clin Infect Dis. 2006;43:585-592.
8. Cilla G, Oñate E, Perez-Yarza EG, et al. Viruses in community-acquired pneumonia in children aged less than 3 years old: High rate of viral coinfection. J Med Virol. 2008;80:1843-1849.
9. Drews AL, Atmar RL, Glezen WP, et al. Dual respiratory virus infections. Clin Infect Dis. 1997;25:1421-1429.
10. Fabbiani M, Terrosi C, Martorelli B, et al. Epidemiological and clinical study of viral respiratory tract infections in children from Italy J Med Virol. 2009;81:750-756.
11. Huang JJ, Huang TY, Huang MY, et al. Simultaneous multiple viral infections in childhood acute lower respiratory tract infections in southern Taiwan. J Trop Pediatr. 1998;44:308-311.
12. Jennings LC, Anderson TP, Beynon KA, et al. Incidence and characteristics of viral community-acquired pneumonia in adults. Thorax. 2008;63:42-48.
13. Legg JP, Warner JA, Johnston SL, et al. Frequency of detection of picornavi-ruses and seven other respiratory pathogens in infants. Pediatr Infect Dis J. 2005;24:611-616.
14. Midulla F, Scagnolari C, Bonci E, et al. Respiratory syncytial virus, human bocavirus and rhinovirus bronchiolitis in infants. Arch Dis Child. 2010;95:35-41.
15. Peng D, Zhao D, Liu J, et al. Multipathogen infections in hospitalized children with acute respiratory infections. Virol J. 2009;6:155.
16. Stempel HE, Martin ET, Kuypers J, et al. Multiple viral respiratory pathogens in children with bronchiolitis. Acta Paediatr. 2009;98:123-126.
17. Sung RY, Chan PK, Tsen T, et al. Identification of viral and atypical bacterial pathogens in children hospitalized with acute respiratory infections in Hong Kong by multiplex PCR assays. J Med Virol. 2009;81:153-159.
18. Templeton KE, Scheltinga SA, van den Eeden WC, et al. Improved diagnosis of the etiology of community-acquired pneumonia with real-time polymerase chain reaction. Clin Infect Dis. 2005;41:345-351.
19. Tristram DA, Miller RW, McMillan JA, et al. Simultaneous infection with respiratory syncytial virus and other respiratory pathogens. Am J Dis Child. 1988;142:834-836.
20. van der Zalm MM, Uiterwaal CS, Wilbrink B, et al. Respiratory pathogens in respiratory tract illnesses during the first year of life: a birth cohort study. Pediatr Infect Dis J. 2009;28:472-A76.
21. Yoshida LM, Suzuki M, Yamamoto T, et al. Viral pathogens associated with acute respiratory infections in central Vietnamese children. Pediatr Infect Dis J. 2010;29:75-77.
22. Zhang HY, Li ZM, Zhang GL, et al. Respiratory viruses in hospitalized children with acute lower respiratory tract infections in harbin, China. Jpn J Infect Dis. 2009;62:458-460.
23. Brogden KA, Guthmiller JM, Taylor CE. Human polymicrobial infections. Lancet. 2005;365:253-255.
24. Esposito S, Bosis S, Niesters HG, et al. Impact of human bocavirus on children and their families. J Clin Microbiol. 2008;46:1337-1342.
25. Paranhos-Baccalà G, Komurian-Pradel F, Richard N, et al. Mixed respiratory virus infections. J Clin Virol. 2008;43:407410.
26. Gray GC, Capuano AW, Setterquist SF, et al. Multi-year study of human metapneumovirus infection at a large US Midwestern Medical Referral Center. J Clin Virol. 2006;37:269-276.
27. Lu X, Erdman DD Molecular typing of human adenoviruses by PCR and sequencing of a partial region of the hexon gene. Arch Virol. 2006;151:15 87-1602.
28. Mulders MN, Salminen M, Kalkkinen N, et al. Molecular epidemiology of coxsackievirus B4 and disclosure of the correct VPl/2A(pro) cleavage site: evidence for high genomic diversity and long-term endemicity of distinct genotypes. J Gen Virol. 2000;81(Pt 3):803-812.
29. Savolainen C, Blomqvist S, Mulders MN, et al. Genetic clustering of all 102 human rhinovirus prototype strains: serotype 87 is close to human enterovirus 70. J Gen Virol. 2002;83(Pt 2):333-340.
30. Sloots TP, McErlean P, Speicher DJ, et al. Evidence of human Coronavirus HKUl and human bocavirus in Australian children. J Clin Virol. 2006;35:99-102.
31. Tamura K, Dudley J, Nei M, et al. MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0. Mol Biol Evol. 2007;24:1596-1599.
32. Martin ET, Kuypers J, Wald A, et al. Multiple versus single virus respiratory infections: viral load and clinical disease severity in hospitalized children. Influenza Other Respi Viruses. 2012;6:71-77.
33. Smith H, Sweet C. Cooperation between viral and bacterial pathongens in causing human respiratory disease. In: Brogden KA, Guthmiller JM, eds. Polymicrobial Diseases. Washington, DC: ASM Press; 2002:201-212.
34. Marcos MA, Esperatti M, Torres A. Viral pneumonia. Curr Opin Infect Dis. 2009;22:143-147.
35. Honkinen M, Lahti E, Österback R, et al. Viruses and bacteria in sputum samples of children with community-acquired pneumonia. Clin Microbiol Infect. 2012;18:300-307.
36. Johansson N, Kalin M, Hedlund J. Clinical impact of combined viral and bacterial infection in patients with community-acquired pneumonia. Scand J Infect Dis. 2011;43:609-615.
37. Michelow IC, Olsen K, Lozano J, et al. Epidemiology and clinical characteristics of community-acquired pneumonia in hospitalized children. Pediatrics. 2004;113:701-707.