Viruses in community-acquired pneumonia in children aged less than 3 years old: High rate of viral coinfection

Journal of Medical Virology

Volumn 80, Issue 10, 2008, Pages 1843-1849

  Cilla, Gustavo ^a   Oñate, Eider ^a   Perez Yarza, Eduardo G ^a   Montes, Milagrosa ^a,b   Vicente, Diego ^a,b   Perez Trallero, Emilio ^a,b,c  

^a HOSPITAL DONOSTIA   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

Author keywords

Human bocavirus; Human metapneumovirus; Parainfluenza virus type 4; Viral coinfections

Indexed keywords

ARTICLE; BOCAVIRUS; COMMUNITY ACQUIRED PNEUMONIA; GENOTYPE; HOSPITAL ADMISSION; HOSPITALIZATION; HUMAN; INCIDENCE; INFECTION RATE; MAJOR CLINICAL STUDY; METAPNEUMOVIRUS; MIXED INFECTION; MOLECULAR BIOLOGY; PARAINFLUENZA VIRUS; PRESCHOOL CHILD; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; RESPIRATORY VIRUS; RHINOVIRUS; SPAIN; VIRUS CULTURE; VIRUS DETECTION;

AGE FACTORS; BOCAVIRUS; CHILD; CHILD, PRESCHOOL; COMMUNITY-ACQUIRED INFECTIONS; COMORBIDITY; HUMANS; INFANT; INFANT, NEWBORN; METAPNEUMOVIRUS; PARAMYXOVIRIDAE; PARAMYXOVIRIDAE INFECTIONS; PARVOVIRIDAE INFECTIONS; PICORNAVIRIDAE INFECTIONS; PNEUMONIA, VIRAL; PROSPECTIVE STUDIES; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUSES; RHINOVIRUS; SPAIN;

ADENOVIRIDAE; HUMAN BOCAVIRUS; HUMAN METAPNEUMOVIRUS; HUMAN PARAINFLUENZA VIRUS 4; PARAINFLUENZA VIRUS; RESPIRATORY SYNCYTIAL VIRUS; RHINOVIRUS; SUBGROUP A; SUBGROUP B;

EID: 50849142594     PISSN: 01466615     EISSN: 10969071     Source Type: Journal    
DOI: 10.1002/jmv.21271     Document Type: Article

References (36)

1. Aberle JH, Aberle SW, Pracher E, Hutter H-P, Kundi M, Popow-Kraupp T. 2005. Single versus dual respiratory virus infections in hospitalized infants. Pediatr Infect Dis J 24:605-610.
2. Allander T, Tammi MT, Eriksson M, Bjerkner A, Tiveljung-Lindell A, Andersson B. 2005. Cloning of a human parvovirus by molecular screening of respiratory tract samples. Proc Natl Acad Sci USA 102:12891-12896. Erratum Proc Natl Acad Sci USA 102:15712.
3. Allander T, Jartti T, Gupta S, Niesters HG, Lehtinen P, Osterback R, Vuorinen T, Waris M, Bjerkner A, Tiveljung-Lindell A, van den Hoogen BG, Hyypia T, Ruuskanen O. 2007. Human bocavirus and acute wheezing in children. Clin Infect Dis 44:904-90410.
4. Bastien N, Brandt K, Dust K, Ward D, Li Y. 2006. Human bocavirus infection, Canada. Emerg Infect Dis 12:848-850.
5. Choi EH, Lee HJ, Kim SJ, Eun BW, Kim NH, Lee JA, Lee JH, Song EK, Kim SH, Park JY, Sung JY. 2006. The association of newly identified respiratory viruses with lower respiratory tract infections in Korean children, 2000-2005. Clin Infect Dis 43:585-592.
6. Coirás MT, Aguilar JC, García ML, Casas I, Pérez-Breña P. 2004. Simultaneous detection of fourteen respiratory viruses in clinical specimens by two multiplex reverse transcription nested-PCR assays. J Med Virol 72:484-495.
7. Drews AL, Atmar RL, Glezen WP, Baxter BD, Piedra PA, Greenberg SB. 1997. Dual respiratory virus infections. Clin Infect Dis 25:1421-1429.
8. Drosten C, Gunther S, Preiser W, van der Werf S, Brodt HR, Becker S, Rabenau H, Panning M, Kolesnikova L, Fouchier RA, Berger A, Burguiere AM, Cinatl J, Eickmann M, Escriou N, Grywna K, Kramme S, Manuguerra JC, Muller S, Rickerts V, Sturmer M, Vieth S, Klenk HD, Osterhaus AD, Schmitz H, Doerr HW. 2003. Identification of a novel coronavirus in patients with severe acute respiratory syndrome. N Engl J Med 348:1967-1976.
9. Fouchier RA, Bestebroer TM, Herfst S, van der Kemp L, Rimmelzwaan GF, Osterhaus AD. 2000. Detection of influenza A viruses from different species by PCR amplification of conserved sequences in the matrix gene. J Clin Microbiol 38:4096-4101.
10. Foulongne V, Guyon G, Rodière M, Segondy M. 2006. Human metapneumovirus infection in young children hospitalized with respiratory tract disease. Pediatr Infect Dis J 25:354-359.
11. Fry AM, Lu X, Chittaganpitch M, Peret T, Fischer J, Dowell SF, Anderson LJ, Erdman D, Olsen SJ. 2007. Human bocavirus: A novel parvovirus epidemiologically associated with pneumonia requiring hospitalization in Thailand. J Infect Dis 195:1038-1045.
12. Garcia Garcia ML, Aguilar Ruiz J, Echeverria Mayo JE, Calvo Rey C, Pinto Fuentes I, Ordobas Gabin M, Roman Riechmann E, Perez Brena P. 2002. Parainfluenza virus type 4 infections. An Esp Pediatr 57:116-120.
13. Greensill J, McNamara PS, Dove W, Flanagan B, Smyth RL, Hart CA. 2003. Human metapneumovirus in severe respiratory syncytial virus bronchiolitis. Emerg Infect Dis 9:372-375.
14. Henrickson KJ, Hoover S, Kehl KS, Hua W. 2004. National disease burden of respiratory viruses detected in children by polymerase chain reaction. Pediatr Infect Dis J 23:S11-S18.
15. Juvén T, Mertsola J, Waris M, Leinonen M, Meurman O, Roivainen M, Eskola J, Saikku P, Ruuskanen O. 2000. Etiology of community-acquired pneumoniain 254 hospitalized children. Pediatr Infect Dis J 19:293-298.
16. Kaida A, Iritani N, Kubo H, Shiomi M, Kohdera U, Murakami T. 2006. Seasonal distribution and phylogenetic analysis of human metapneumovirus among children in Osaka City, Japan. J Clin Virol 35:394-399.
17. Lau SK, To WK, Tse PW, Chan AK, Woo PC, Tsoi HW, Leung AF, Li KS, Chan PK, Lim WW, Yung RW, Chan KH, Yuen KY. 2005. Human parainfluenza virus 4 outbreak and the role of diagnostic tests. J Clin Microbiol 43:4515-4521.
18. Michelow IC, Olsen K, Lozano J, Rollins NK, Duffy LB, Ziegler T, Kauppila J, Leinonen M, McCracken GH, Jr. 2004. Epidemiology and clinical characteristics of community-acquired pneumonia in hospitalized children. Pediatrics 113:701-707.
19. Peck AJ, Holman RC, Curns AT, Lingappa JR, Cheek JE, Singleton RJ, Carver K, Anderson LJ. 2005. Lower respiratory tract infections among American Indian and Alaska native children and the general population of U.S. children. Pediatr Infect Dis J 24:342-351.
20. Ruuskanen O, Mertsola J. 1999. Childhood community-acquired pneumonia. Semin Respir Infect 14:163-172.
21. Schildgen O, Müller A, Allander T, Mackay IM, Völz S, Kupfer B, Simon A. 2008. Human bocavirus: Passenger or pathogen in acute respiratory tract infections? Clin Microbiol Rev 21:291-304.
22. Sinaniotis CA, Sinaniotis AC. 2005. Community-acquired pneumonia in children. Curr Opin Pulm Med 11:218-225.
23. Steininger C, Aberle SW, Popow-Kraupp T. 2001. Early detection of acute rhinovirus infections by a rapid reverse transcription-PCR assay. J Clin Microbiol 39:129-133.
24. Stockton J, Ellis JS, Saville M, Clewley JP, Zambon MC. 1998. Multiplex PCR for typing and subtyping influenza and respiratory syncytial viruses. J Clin Microbiol 36:2990-2995.
25. Templeton KE, Scheltinga SA, van den Eeden WCJFM, Graffelman AW, van den Broek PJ, Claas ECJ. 2005. Improved diagnosis of the etiology of community-acquired pneumonia with real-time polymerase chain reaction. Clin Infect Dis 41:345-351.
26. Tsolia MN, Psarras S, Bossios A, Audi H, Paldanius M, Gourgiotis D, Kallergi K, Kafetzis DA, Constantopoulos A, Papadopoulos NG. 2004. Etiology of community-acquired pneumonia in bospitalized school-age children: Evidence for high prevalence of viral infections. Clin Infect Dis 39:681-686.
27. Vabret A, Mourez T, Dina J, van der Hoek L, Gouarin S, Petitjean J, Brouard J, Freymuth F. 2005. Human coronavirus NL63, France. Emerg Infect Dis 11:1225-1229.
28. van den Hoogen BG, de Jong JC, Groen J, Kuiken T, de Groot R, Fouchier RA, Osterhaus AD. 2001. A newly discovered human pneumovirus isolated from young children with respiratory tract disease. Nat Med 7:719-724.
29. van der Hoek L, Pyre K, Jebbink MF, Vermeulen-Oost W, Berkhout RJ, Wolthers KC, Wertheim-van Dillen PM, Kaandorp J, Spaargaren J, Berkhout B. 2004. Identification of a new coronavirus. Nat Med 10:368-373.
30. van der Hoek L, Sure K, Ihorst G, Stang A, Pyre K, Jebbink MF, Petersen G, Forster J, Berkhout B, Uberla K. 2005. Croup is associated with the novel coronavirus NL63. PLOS Med 2:e240. 10.1371/journal.pmed.0020240.
31. Vicente D, Cilla G, Montes M, Pérez-Yarza EG, Pérez Trallero E. 2007. Human bocavirus, a respiratory and enteric virus. Emerg Infect Dis 13:636-637.
32. World Health Organization Pneumonia Vaccine Trial Investigators' Group. 2001. Standardization of interpretation of chest radiographs for the diagnosis of pneumonia in children. Available on the Internet at http://www.who.int/ vaccines-documents/DocsPDF01/www616.pdf.
33. Williams BG, Gouws E, Boschi-Pinto C, Bryce J, Dye C. 2002. Estimates of world-wide distribution of child deaths from acute respiratory infections. Lancet Infect Dis 2:25-32.
34. Williams JV, Harris PA, Tollefson SJ, Halburnt-Rush LL, Pingsterhaus JM, Edwards KM, Wright PF, Crowe JE, Jr. 2004. Human metapneumovirus and lower respiratory tract disease in otherwise healthy infants and children. N Engl J Med 350:443-450.
35. Wolf DG, Greenberg D, Kalkstein D, Shemer-Avni Y, Givon-Lavi N, Saleh N, Goldberg MD, Dagan R. 2006. Comparison of human metapneumovirus, respiratory syncytial virus and influenza A virus lower respiratory tract infections in hospitalised young children. Pediatr Infect Dis J 25:320-324.
36. Xu W, McDonough MC, Erdman DD. 2000. Species-specific identification of human adenoviruses by a multiplex PCR assay. J Clin Microbiol 38:4114-4120.