Frequent detection of viral coinfection in children hospitalized with acute respiratory tract infection using a real-time polymerase chain reaction

Pediatric Infectious Disease Journal

Volumn 27, Issue 7, 2008, Pages 589-594

  Bonzel, Linda ^a   Tenenbaum, Tobias ^a   Schroten, Horst ^a   Schildgen, Oliver ^b   Schweitzer Krantz, Susanne ^c   Adams, Ortwin ^a,d  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b UNIVERSITY OF BONN   (Germany)

^c Children s Hospital   (Germany)

^d Geb 2221   (Germany)

Author keywords

Real time PCR; Respiratory viruses; Viral coinfection

Indexed keywords

ARTICLE; BOCAVIRUS; BRONCHIOLITIS; BRONCHITIS; CHILD; CHILD HOSPITALIZATION; CONTROLLED STUDY; DIAGNOSTIC PROCEDURE; DNA VIRUS; HUMAN; MAJOR CLINICAL STUDY; MIXED INFECTION; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; RESPIRATORY TRACT INFECTION; RESPIRATORY VIRUS; RHINOVIRUS; RNA VIRUS; SENSITIVITY AND SPECIFICITY; VIRUS DETECTION; VIRUS PNEUMONIA; ADOLESCENT; COMORBIDITY; ISOLATION AND PURIFICATION; METHODOLOGY; NEWBORN; PICORNAVIRUS INFECTION; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; VIROLOGY; VIRUS; VIRUS INFECTION;

ADOLESCENT; BOCAVIRUS; CHILD; CHILD, HOSPITALIZED; CHILD, PRESCHOOL; COMORBIDITY; HUMANS; INFANT, NEWBORN; PARVOVIRIDAE INFECTIONS; PICORNAVIRIDAE INFECTIONS; POLYMERASE CHAIN REACTION; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUSES; RESPIRATORY TRACT INFECTIONS; RHINOVIRUS; VIRUS DISEASES; VIRUSES;

EID: 50949122689     PISSN: 08913668     EISSN: 15320987     Source Type: Journal    
DOI: 10.1097/INF.0b013e3181694fb9     Document Type: Article

References (22)

1. Legg JP,Warner JA, Johnston SL,Warner JO. Frequency of detection of picornaviruses and seven other respiratory pathogens in infants. Pediatr Infect Dis J. 2005;24:611-616.
2. Weigl JA, Puppe W, Belke O, Neususs J, Bagci F, Schmitt HJ. The descriptive epidemiology of severe lower respiratory tract infections in children in Kiel, Germany. Klin Padiatr. 2005;217:259-267.
3. Kim YJ, Boeckh M, Englund JA. Community respiratory virus infections in immunocompromised patients: hematopoietic stem cell and solid organ transplant recipients, and individuals with human immuno-deficiency virus infection. Semin Respir Crit Care Med. 2007;28:222-242.
4. Falsey AR, Walsh EE. Viral pneumonia in older adults. Clin Infect Dis. 2006;42:518-524.
5. Falsey AR, Walsh EE. Respiratory syncytial virus infection in elderly adults. Drugs Aging. 2005;22:577-587.
6. Walsh EE, Falsey AR, Hennessey PA. Respiratory syncytial and other virus infections in persons with chronic cardiopulmonary disease. Am J Respir Crit Care Med. 1999;160:791-795.
7. van den Hoogen BG, de Jong JC, Groen J, et al. A newly discovered human pneumovirus isolated from young children with respiratory tract disease. Nat Med. 2001;7:719-724.
8. Pyrc K, Berkhout B, van der HL. Identification of new human coronaviruses. Expert Rev Anti Infect Ther. 2007;5:245-253.
9. Pyrc K, Berkhout B, van der HL. The novel human coronaviruses NL63 and HKU1. J Virol. 2007;81:3051-3057.
10. Allander T, Tammi MT, Eriksson M, Bjerkner A, Tiveljung-Lindell A, Andersson B. Cloning of a human parvovirus by molecular screening of respiratory tract samples. Proc Natl Acad Sci USA. 2005;102:12891-12896.
11. Foulongne V, Olejnik Y, Perez V, Elaerts S, Rodiere M, Segondy M. Human bocavirus in French children. Emerg Infect Dis. 2006;12:1251-1253.
12. Ma X, Endo R, Ishiguro N, et al. Detection of human bocavirus in Japanese children with lower respiratory tract infections. J Clin Microbiol. 2006;44:1132-1134.
13. Arden KE, McErlean P, Nissen MD, Sloots TP, Mackay IM. Frequent detection of human rhinoviruses, paramyxoviruses, coronaviruses, and bocavirus during acute respiratory tract infections. J Med Virol. 2006; 78:1232-1240.
14. Sloots TP, McErlean P, Speicher DJ, Arden KE, Nissen MD, Mackay IM. Evidence of human coronavirus HKU1 and human bocavirus in Australian children. J Clin Virol. 2006;35:99-102.
15. Arnold JC, Singh KK, Spector SA, Sawyer MH. Human bocavirus: prevalence and clinical spectrum at a children's hospital. Clin Infect Dis. 2006;43:283-288.
16. Choi EH, Lee HJ, Kim SJ, et al. The association of newly identified respiratory viruses with lower respiratory tract infections in Korean children, 2000-2005. Clin Infect Dis. 2006;43:585-592.
17. Weissbrich B, Neske F, Schubert J, et al. Frequent detection of bocavirus DNA in German children with respiratory tract infections. BMC Infect Dis. 2006;6:109.
18. Templeton KE, Scheltinga SA, Beersma MF, Kroes AC, Claas EC. Rapid and sensitive method using multiplex real-time PCR for diagnosis of infections by influenza a and influenza B viruses, respiratory syncytial virus, and parainfluenza viruses 1, 2, 3, and 4. J Clin Microbiol. 2004;42:1564-1569.
19. Gunson RN, Collins TC, Carman WF. Real-time RT-PCR detection of 12 respiratory viral infections in four triplex reactions. J Clin Virol. 2005;33:341-344.
20. Coiras MT, Aguilar JC, Garcia ML, Casas I, Perez-Brena P. Simultaneous detection of fourteen respiratory viruses in clinical specimens by two multiplex reverse transcription nested-PCR assays. J Med Virol. 2004;72:484-495.
21. Scheltinga SA, Templeton KE, Beersma MF, Claas EC. Diagnosis of human metapneumovirus and rhinovirus in patients with respiratory tract infections by an internally controlled multiplex real-time RNA PCR. J Clin Virol. 2005;33:306-311.
22. Falsey AR, Criddle MC, Walsh EE. Detection of respiratory syncytial virus and human metapneumovirus by reverse transcription polymerase chain reaction in adults with and without respiratory illness. J Clin Virol. 2006;35:46-50.