The human milk oligosaccharide 2′-fucosyllactose attenuates the severity of experimental necrotising enterocolitis by enhancing mesenteric perfusion in the neonatal intestine

British Journal of Nutrition

Volumn 116, Issue 7, 2016, Pages 1175-1187

  Good, Misty ^a,b   Sodhi, Chhinder P ^c,d   Yamaguchi, Yukihiro ^c,d   Jia, Hongpeng ^c,d   Lu, Peng ^c,d   Fulton, William B ^c,d   Martin, Laura Y ^c,d   Prindle, Thomas ^c,d   Nino, Diego F ^c,d   Zhou, Qinjie ^c,d   Ma, Congrong ^a,b   Ozolek, John A ^a,b   Buck, Rachael H ^e   Goehring, Karen C ^e   Hackam, David J ^c,d  

^a CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c JOHNS HOPKINS CHILDREN S CENTER   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e ABBOTT LABORATORIES   (United States)

Author keywords

2 Fucosyllactose; Breast milk; Endothelial nitric oxide synthase; Human milk oligosaccharides; Necrotising enterocolitis

Indexed keywords

2' FUCOSYLLACTOSE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; OLIGOSACCHARIDE; RNA 16S; UNCLASSIFIED DRUG; 2'-FUCOSYLLACTOSE; NITRIC OXIDE; TRISACCHARIDE;

AMPLICON; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY ASSESSMENT; ENDOTHELIUM; ENDOTHELIUM CELL; ENZYME INDUCTION; HUMAN; HUMAN CELL; HUVEC CELL LINE; INTESTINE BLOOD FLOW; INTESTINE FLORA; INTESTINE MUCOSA; INTESTINE PERFUSION; MOUSE; NECROTIZING ENTEROCOLITIS; NEWBORN; NONHUMAN; PERFUSION; PROTECTION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; SMALL INTESTINE; UPREGULATION; WILD TYPE; ANIMAL; BREAST MILK; C57BL MOUSE; CHEMISTRY; DEFICIENCY; DISEASE MODEL; DRUG EFFECTS; ENTEROCOLITIS, NECROTIZING; FEMALE; GENE EXPRESSION; GENETICS; KNOCKOUT MOUSE; MICROFLORA; PATHOPHYSIOLOGY; PHYSIOLOGY; PREMATURITY; SPLANCHNIC BLOOD FLOW; VASCULARIZATION;

ANIMALS; ANIMALS, NEWBORN; DISEASE MODELS, ANIMAL; ENTEROCOLITIS, NECROTIZING; FEMALE; GENE EXPRESSION; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE, DISEASES; INTESTINAL MUCOSA; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROBIOTA; MILK, HUMAN; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; SPLANCHNIC CIRCULATION; TRISACCHARIDES;

EID: 85027935277     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114516002944     Document Type: Article

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