Breast milk protects against the development of necrotizing enterocolitis through inhibition of Toll-like receptor 4 in the intestinal epithelium via activation of the epidermal growth factor receptor

Mucosal Immunology

Volumn 8, Issue 5, 2015, Pages 1166-1179

  Good, M ^a,b   Sodhi, C P ^c,d   Egan, C E ^a,b   Afrazi, A ^a,b   Jia, H ^c,d   Yamaguchi, Y ^c,d   Lu, P ^a,b   Branca, M F ^a,b   Ma, C ^a,b   Prindle, T ^c,d   Mielo, S ^a,b   Pompa, A ^a,b   Hodzic, Z ^a,b   Ozolek, J A ^a,b   Hackam, D J ^c,d  

^a CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c JOHNS HOPKINS CHILDREN S CENTER   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; GLYCOGEN SYNTHASE KINASE 3BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TOLL LIKE RECEPTOR 4; EGFR PROTEIN, MOUSE; GLYCOGEN SYNTHASE KINASE 3; GSK3B PROTEIN, MOUSE; TLR4 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BREAST MILK; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME ACTIVATION; ENZYME INHIBITION; GENE OVEREXPRESSION; IN VITRO STUDY; IN VIVO STUDY; INTESTINE CELL; INTESTINE EPITHELIUM; MOUSE; NECROTIZING ENTEROCOLITIS; NEWBORN; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ANIMAL; CELL LINE; ENTEROCOLITIS, NECROTIZING; FEMALE; GENETICS; IMMUNOLOGY; MILK; PATHOLOGY;

ANIMALS; APOPTOSIS; CELL LINE; ENTEROCOLITIS, NECROTIZING; ENTEROCYTES; EPIDERMAL GROWTH FACTOR; FEMALE; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; MICE; MILK; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

EID: 84939479232     PISSN: 19330219     EISSN: 19353456     Source Type: Journal    
DOI: 10.1038/mi.2015.30     Document Type: Article

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