The purinergic receptor subtype P2Y2 mediates chemotaxis of neutrophils and fibroblasts in fibrotic lung disease

Oncotarget

Volumn 8, Issue 22, 2017, Pages 35962-35972

  Müller, Tobias ^a,b   Fay, Susanne ^a   Vieira, Rodolfo Paula ^a   Harry, Karmouty Quintana ^c   Cicko, Sanja ^a   Ayata, Korcan ^a   Zissel, Gernot ^a   Goldmann, Torsten ^d   Lungarella, Giuseppe ^e   Ferrari, Davide ^f   Di Virgilio, Francesco ^f   Robaye, Bernard ^g   Boeynaems, Jean Marie ^g   Blackburn, Michael R ^c   Idzko, Marco ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^c UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^d RESEARCH CENTER BORSTEL   (Germany)

^e UNIVERSITY OF SIENA   (Italy)

^f UNIVERSITY OF FERRARA   (Italy)

^g ERASME HOSPITAL   (Belgium)

Author keywords

ATP; Chemotaxis; Neutrophils; Nucleotides; Pulmonary fibrosis

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALPHA 1 PROCOLLAGEN; INTERLEUKIN 6; KERATINOCYTE DERIVED CHEMOKINE; PROCOLLAGEN; PURINERGIC P2Y2 RECEPTOR; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; URIDINE TRIPHOSPHATE; BIOLOGICAL MARKER;

ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLEOMYCIN-INDUCED PULMONARY FIBROSIS; BRONCHOALVEOLAR LAVAGE FLUID; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; FIBROSING ALVEOLITIS; HUMAN; HUMAN CELL; IN VIVO STUDY; INFLAMMATION; INFLAMMATORY CELL; LUNG ALVEOLUS MACROPHAGE; LUNG FIBROBLAST; MALE; MIDDLE AGED; MOUSE; MOUSE MODEL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PATHOGENESIS; PROTEIN EXPRESSION; UPREGULATION; VERY ELDERLY; WILD TYPE; ANIMAL; CHEMOTAXIS; DISEASE MODEL; EXTRACELLULAR SPACE; FIBROBLAST; FIBROSIS; GENE EXPRESSION; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; LUNG FUNCTION TEST; METABOLISM; NEUTROPHIL; PATHOLOGY; PATHOPHYSIOLOGY;

ADENOSINE TRIPHOSPHATE; AGED; AGED, 80 AND OVER; ANIMALS; BIOMARKERS; CELL PROLIFERATION; CHEMOTAXIS; DISEASE MODELS, ANIMAL; EXTRACELLULAR SPACE; FEMALE; FIBROBLASTS; FIBROSIS; GENE EXPRESSION; HUMANS; IDIOPATHIC PULMONARY FIBROSIS; MALE; MICE; MICE, KNOCKOUT; MIDDLE AGED; NEUTROPHILS; RECEPTORS, PURINERGIC P2Y2; RESPIRATORY FUNCTION TESTS;

EID: 85027883875     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: None     Document Type: Article

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