Tanshinone IIA Elicits Neuroprotective Effect Through Activating the Nuclear Factor Erythroid 2-Related Factor-Dependent Antioxidant Response

Rejuvenation Research

Volumn 20, Issue 4, 2017, Pages 286-297

  Cai, Min ^a   Guo, Yongxin ^a   Wang, Shiquan ^a   Wei, Haidong ^b   Sun, Sisi ^c   Zhao, Guangchao ^a   Dong, Hailong ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b THE SECOND AFFILIATED HOSPITAL OF XI AN JIAOTONG UNIVERSITY   (China)

^c Department of Ophthalmology   (China)

Author keywords

cerebral ischemia reperfusion; experimental stroke; nuclear factor erythroid tworelated factor; oxidative stress; tanshinone IIA

Indexed keywords

CASPASE 3; CATALASE; GLUTATHIONE; MESSENGER RNA; SUPEROXIDE; TANSHINONE IIA; TRANSCRIPTION FACTOR NRF2; ABIETANE DERIVATIVE; ANTIOXIDANT; NEUROPROTECTIVE AGENT; TANSHINONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN PERFUSION; CONTROLLED STUDY; DRUG EFFICACY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; ANIMAL; CELL NUCLEUS; COMPLICATION; DRUG EFFECT; GENE KNOCKDOWN; KNOCKOUT MOUSE; METABOLISM; NERVE CELL; OXIDATION REDUCTION REACTION; PATHOLOGY; PROTEIN TRANSPORT; REPERFUSION INJURY;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; BRAIN ISCHEMIA; CELL NUCLEUS; DITERPENES, ABIETANE; GENE KNOCKDOWN TECHNIQUES; MALE; MICE, KNOCKOUT; NEURONS; NEUROPROTECTIVE AGENTS; NF-E2-RELATED FACTOR 2; OXIDATION-REDUCTION; PROTEIN TRANSPORT; REPERFUSION INJURY;

EID: 85027859787     PISSN: 15491684     EISSN: 15578577     Source Type: Journal    
DOI: 10.1089/rej.2016.1912     Document Type: Article

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