-
1
-
-
84907834785
-
Pharmacological therapies in post stroke recovery: Recommendations for future clinical trials
-
(Epub ahead of print)
-
Chollet F, Cramer SC, Stinear C,et al:Pharmacological therapies in post stroke recovery: recommendations for future clinical trials.J Neurol. (Epub ahead of print) 2013.
-
(2013)
J Neurol.
-
-
Chollet, F.1
Cramer, S.C.2
Stinear, C.3
-
2
-
-
68249115320
-
Injury and repair mechanisms in ischemic stroke: Considerations for the development of novel neurotherapeutics
-
Candelario-Jalil E: Injury and repair mechanisms in ischemic stroke: considerations for the development of novel neurotherapeutics. Curr Opin Investig Drugs 10: 644-654, 2009.
-
(2009)
Curr Opin Investig Drugs
, vol.10
, pp. 644-654
-
-
Candelario-Jalil, E.1
-
3
-
-
84984763363
-
Mechanisms, challenges and opportunities in stroke
-
Lo EH, Dalkara T and Moskowitz MA: Mechanisms, challenges and opportunities in stroke. Nat Rev Neurosci 4: 399-415, 2003.
-
(2003)
Nat Rev Neurosci
, vol.4
, pp. 399-415
-
-
Lo, E.H.1
Dalkara, T.2
Moskowitz, M.A.3
-
4
-
-
0034652113
-
Thioredoxin reductase
-
Mustacich D and Powis G: Thioredoxin reductase. Biochem J 346 Pt 1: 1-8, 2000.
-
(2000)
Biochem J
, vol.346
, pp. 1-8
-
-
Mustacich, D.1
Powis, G.2
-
5
-
-
77955064121
-
Cytosolic phospholipase A2 alpha amplifies early cyclooxygenase-2 expression, oxidative stress and MAP kinase phosphorylation after cerebral ischemia in mice
-
Kishimoto K, Li RC, Zhang J, et al: Cytosolic phospholipase A2 alpha amplifies early cyclooxygenase-2 expression, oxidative stress and MAP kinase phosphorylation after cerebral ischemia in mice. J Neuroinflammation 7: 42, 2010.
-
(2010)
J Neuroinflammation
, vol.7
, pp. 42
-
-
Kishimoto, K.1
Li, R.C.2
Zhang, J.3
-
6
-
-
20044373092
-
Localization of nitric oxide synthase in rat trigeminal primary afferent neurons using NADPH-diaphorase histochemistry
-
Stoyanova II and Lazarov NE: Localization of nitric oxide synthase in rat trigeminal primary afferent neurons using NADPH-diaphorase histochemistry. J Mol Histol 36:187-193, 2005.
-
(2005)
J Mol Histol
, vol.36
, pp. 187-193
-
-
Stoyanova, I.I.1
Lazarov, N.E.2
-
7
-
-
0024378999
-
Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum
-
Bredt DS and Snyder SH: Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum. Proc Natl Acad Sci USA 86: 9030-9033, 1989.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 9030-9033
-
-
Bredt, D.S.1
Snyder, S.H.2
-
8
-
-
0030569336
-
Inducible nitric oxide synthase following hypoxia in rat cultured glial cells
-
Kawase M, Kinouchi H, Kato I, et al: Inducible nitric oxide synthase following hypoxia in rat cultured glial cells. Brain Res 738: 319-322, 1996.
-
(1996)
Brain Res
, vol.738
, pp. 319-322
-
-
Kawase, M.1
Kinouchi, H.2
Kato, I.3
-
10
-
-
46349090011
-
Novel approaches to treat oxidative stress and cardiovascular diseases
-
Berk BC: Novel approaches to treat oxidative stress and cardiovascular diseases. Trans Am Clin Climatol Assoc 118: 209-214, 2007.
-
(2007)
Trans Am Clin Climatol Assoc
, vol.118
, pp. 209-214
-
-
Berk, B.C.1
-
11
-
-
55349088554
-
Thioredoxin-1 and its natural inhibitor, vitamin D3 up-regulated protein 1, are differentially regulated by PPARalpha in human macrophages
-
Billiet L, Furman C, Cuaz-Pérolin C, et al: Thioredoxin-1 and its natural inhibitor, vitamin D3 up-regulated protein 1, are differentially regulated by PPARalpha in human macrophages. J Mol Biol 384: 564-576, 2008.
-
(2008)
J Mol Biol
, vol.384
, pp. 564-576
-
-
Billiet, L.1
Furman, C.2
Cuaz-Pérolin, C.3
-
12
-
-
1642569593
-
Thioredoxin and its role in toxicology
-
Watson HW, Yang X, Choi YE, Jones DP and Kehrer JP: Thioredoxin and its role in toxicology. Toxicol Sci 78: 3-14, 2004.
-
(2004)
Toxicol Sci
, vol.78
, pp. 3-14
-
-
Watson, H.W.1
Yang, X.2
Choi, Y.E.3
Jones, D.P.4
Kehrer, J.P.5
-
13
-
-
70349241906
-
Cardioprotective effects of tanshinone IIA on myocardial ischemia injury in rats
-
Xu W, Yang J and Wu LM: Cardioprotective effects of tanshinone IIA on myocardial ischemia injury in rats. Pharmazie 64: 332-336, 2009.
-
(2009)
Pharmazie
, vol.64
, pp. 332-336
-
-
Xu, W.1
Yang, J.2
Wu, L.M.3
-
14
-
-
0038249044
-
Neuroprotective effects of tanshinones in transient focal cerebral ischemia in mice
-
Lam BY, Lo AC, Sun X, Luo HW, Chung SK and Sucher NJ: Neuroprotective effects of tanshinones in transient focal cerebral ischemia in mice. Phytomedicine 10: 286-291, 2003.
-
(2003)
Phytomedicine
, vol.10
, pp. 286-291
-
-
Lam, B.Y.1
Lo, A.C.2
Sun, X.3
Luo, H.W.4
Chung, S.K.5
Sucher, N.J.6
-
15
-
-
65649128507
-
Neuroprotective effects of Tanshinone IIA on permanent focal cerebral ischemia in mice
-
Dong K, Xu W, Yang J, Qiao H and Wu L: Neuroprotective effects of Tanshinone IIA on permanent focal cerebral ischemia in mice. Phytother Res 23: 608-613, 2009.
-
(2009)
Phytother Res
, vol.23
, pp. 608-613
-
-
Dong, K.1
Xu, W.2
Yang, J.3
Qiao, H.4
Wu, L.5
-
16
-
-
34250810703
-
Preclinical and clinical examinations of Salvia miltiorrhiza and its tanshinones in ischemic conditions
-
Adams JD, Wang R, Yang J and Lien EJ: Preclinical and clinical examinations of Salvia miltiorrhiza and its tanshinones in ischemic conditions. Chin Med 1: 3, 2006.
-
(2006)
Chin Med
, vol.1
, pp. 3
-
-
Adams, J.D.1
Wang, R.2
Yang, J.3
Lien, E.J.4
-
17
-
-
77953540227
-
The neuroprotective effects of Tanshinone IIA are associated with induced nuclear translocation of TORC1 and upregulated expression of TORC1, pCREB and BDNF in the acute stage of ischemic stroke
-
Liu LL, Zhang XL, Wang L, et al: The neuroprotective effects of Tanshinone IIA are associated with induced nuclear translocation of TORC1 and upregulated expression of TORC1, pCREB and BDNF in the acute stage of ischemic stroke. Brain Res Bull 82: 228-233, 2010.
-
(2010)
Brain Res Bull
, vol.82
, pp. 228-233
-
-
Liu, L.L.1
Zhang, X.L.2
Wang, L.3
-
18
-
-
34447118246
-
Role of P-glycoprotein in restricting the brain penetration of tanshinone IIA, a major active constituent from the root of Salvia miltiorrhiza Bunge, across the blood-brain barrier
-
Chen X, Zhou ZW, Xue CC, Li XX and Zhou SF: Role of P-glycoprotein in restricting the brain penetration of tanshinone IIA, a major active constituent from the root of Salvia miltiorrhiza Bunge, across the blood-brain barrier. Xenobiotica 37: 635-678, 2007.
-
(2007)
Xenobiotica
, vol.37
, pp. 635-678
-
-
Chen, X.1
Zhou, Z.W.2
Xue, C.C.3
Li, X.X.4
Zhou, S.F.5
-
20
-
-
80053544728
-
Modeling stroke in mice -middle cerebral artery occlusion with the filament model
-
Engel O, Kolodziej S, Dirnagl U and Prinz V: Modeling stroke in mice -middle cerebral artery occlusion with the filament model. J Vis Exp 47: e2423, 2011.
-
(2011)
J Vis Exp
, vol.47
-
-
Engel, O.1
Kolodziej, S.2
Dirnagl, U.3
Prinz, V.4
-
21
-
-
0024494427
-
Reversible middle cerebral artery occlusion without craniectomy in rats
-
Longa EZ, Weinstein PR, Carlson S and Cummins R: Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 20: 84-91, 1989.
-
(1989)
Stroke
, vol.20
, pp. 84-91
-
-
Longa, E.Z.1
Weinstein, P.R.2
Carlson, S.3
Cummins, R.4
-
22
-
-
33746191796
-
Neuroprotection by ovarian hormones in animal models of neurological disease
-
Hoffman GE, Merchenthaler I and Zup SL: Neuroprotection by ovarian hormones in animal models of neurological disease. Endocrine 29: 217-231, 2006.
-
(2006)
Endocrine
, vol.29
, pp. 217-231
-
-
Hoffman, G.E.1
Merchenthaler, I.2
Zup, S.L.3
-
23
-
-
77449130589
-
Tanshinone IIA down-regulates HMGB1, RAGE, TLR4, NF-kappaB expression, ameliorates BBB permeability and endothelial cell function, and protects rat brains against focal ischemia
-
Wang LN, Zhang XJ, Liu LL, et al: Tanshinone IIA down-regulates HMGB1, RAGE, TLR4, NF-kappaB expression, ameliorates BBB permeability and endothelial cell function, and protects rat brains against focal ischemia. Brain Res 1321: 143-151, 2010.
-
(2010)
Brain Res
, vol.1321
, pp. 143-151
-
-
Wang, L.N.1
Zhang, X.J.2
Liu, L.L.3
-
24
-
-
78149407580
-
The effects of Tanshinone IIA on blood-brain barrier and brain edema after transient middle cerebral artery occlusion in rats
-
Tang C, Xue HL, Bai CL, Fu R and Wu AH: The effects of Tanshinone IIA on blood-brain barrier and brain edema after transient middle cerebral artery occlusion in rats. Phytomedicine 17: 1145-1149, 2010.
-
(2010)
Phytomedicine
, vol.17
, pp. 1145-1149
-
-
Tang, C.1
Xue, H.L.2
Bai, C.L.3
Fu, R.4
Wu, A.H.5
-
25
-
-
79956199285
-
Treatment with Z-ligustilide, a component of Angelica sinensis, reduces brain injury after a subarachnoid hemorrhage in rats
-
Chen D, Tang J, Khatibi NH, et al: Treatment with Z-ligustilide, a component of Angelica sinensis, reduces brain injury after a subarachnoid hemorrhage in rats. J Pharmacol Exp Ther 337: 663-672, 2011.
-
(2011)
J Pharmacol Exp Ther
, vol.337
, pp. 663-672
-
-
Chen, D.1
Tang, J.2
Khatibi, N.H.3
-
26
-
-
79955978036
-
Matter of life and death: The pharmacological approaches targeting apoposis in brain diseases
-
Cavallucci V and D'Amelio M: Matter of life and death: the pharmacological approaches targeting apoposis in brain diseases. Curr Pharm Des 17: 215-229, 2011.
-
(2011)
Curr Pharm Des
, vol.17
, pp. 215-229
-
-
Cavallucci, V.1
D'Amelio, M.2
-
27
-
-
39149086351
-
Paeonol and paeoniflorin, the main active principles of Paeonia albiflora, protect the heart from myocardial ischemia/reperfusion injury in rats
-
Nizamutdinova IT, Jin YC, Kim JS, et al: Paeonol and paeoniflorin, the main active principles of Paeonia albiflora, protect the heart from myocardial ischemia/reperfusion injury in rats. Planta Med 74: 14-18, 2008.
-
(2008)
Planta Med
, vol.74
, pp. 14-18
-
-
Nizamutdinova, I.T.1
Jin, Y.C.2
Kim, J.S.3
-
28
-
-
77955571258
-
Tanshinone IIA improves impaired nerve functions in experimental diabetic rats
-
Liu Y, Wang L, Li X, Lv C, Feng D and Luo Z: Tanshinone IIA improves impaired nerve functions in experimental diabetic rats. Biochem Biophys Res Commun 399: 49-54, 2010.
-
(2010)
Biochem Biophys Res Commun
, vol.399
, pp. 49-54
-
-
Liu, Y.1
Wang, L.2
Li, X.3
Lv, C.4
Feng, D.5
Luo, Z.6
-
29
-
-
77957755548
-
Tanshinone IIA protects the human blood-brain barrier model from leukocyte-associated hypoxia-reoxygenation injury
-
Zhang WJ, Feng J, Zhou R, et al: Tanshinone IIA protects the human blood-brain barrier model from leukocyte-associated hypoxia-reoxygenation injury. Eur J Pharmacol 648: 146-152, 2010.
-
(2010)
Eur J Pharmacol
, vol.648
, pp. 146-152
-
-
Zhang, W.J.1
Feng, J.2
Zhou, R.3
-
30
-
-
20444438848
-
Nitric oxide modulates peristaltic muscle activity associated with fluid circulation in the sea pansy Renilla koellikeri
-
Anctil M, Poulain I and Pelletier C: Nitric oxide modulates peristaltic muscle activity associated with fluid circulation in the sea pansy Renilla koellikeri. J Exp Biol 208: 2005-2017, 2005.
-
(2005)
J Exp Biol
, vol.208
, pp. 2005-2017
-
-
Anctil, M.1
Poulain, I.2
Pelletier, C.3
-
31
-
-
0346340021
-
Thioredoxin system in premature and newborn biology
-
Das KC: Thioredoxin system in premature and newborn biology. Antioxid Redox Signal 6: 177-184, 2004.
-
(2004)
Antioxid Redox Signal
, vol.6
, pp. 177-184
-
-
Das, K.C.1
-
32
-
-
1942455833
-
Human mitochondrial thioredoxin reductase reduces cytochrome c and confers resistance to complex III inhibition
-
Nalvarte I, Damdimopoulos AE and Spyrou G: Human mitochondrial thioredoxin reductase reduces cytochrome c and confers resistance to complex III inhibition. Free Rad Biol Med 36: 1270-1278, 2004.
-
(2004)
Free Rad Biol Med
, vol.36
, pp. 1270-1278
-
-
Nalvarte, I.1
Damdimopoulos, A.E.2
Spyrou, G.3
-
33
-
-
44649126021
-
Pinocembrin protects rat brain against oxidation and apoptosis induced by ischemia-reperfusion both in vivo and in vitro
-
Liu R, Gao M, Yang ZH, et al: Pinocembrin protects rat brain against oxidation and apoptosis induced by ischemia-reperfusion both in vivo and in vitro.Brain Res 1216: 104-15, 2008.
-
(2008)
Brain Res
, vol.1216
, pp. 104-115
-
-
Liu, R.1
Gao, M.2
Yang, Z.H.3
-
34
-
-
46149118615
-
Curcuma oil modulates the nitric oxide system response to cerebral ischemia/reperfusion injury
-
Dohare P, Varma S and Ray M: Curcuma oil modulates the nitric oxide system response to cerebral ischemia/reperfusion injury.Nitric Oxide 19: 1-11, 2008.
-
(2008)
Nitric Oxide
, vol.19
, pp. 1-11
-
-
Dohare, P.1
Varma, S.2
Ray, M.3
-
35
-
-
31344439662
-
Free radicals, mitochondria, and hypoxia-ischemia in the developing brain
-
Blomgren K, Hagberg H:Free radicals, mitochondria, and hypoxia-ischemia in the developing brain.Free Radic Biol Med 40:388-97,2006.
-
(2006)
Free Radic Biol Med
, vol.40
, pp. 388-397
-
-
Blomgren, K.1
Hagberg, H.2
|