Multivalent Recruitment of Human Argonaute by GW182

Molecular Cell

Volumn 67, Issue 4, 2017, Pages 646-658.e3

  Elkayam, Elad ^a   Faehnle, Christopher R ^a   Morales, Marjorie ^a,c   Sun, Jingchuan ^b,d   Li, Huilin ^b,e   Joshua Tor, Leemor ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b BROOKHAVEN NATIONAL LABORATORY   (United States)

^c Simons Center for Quantitative Biology   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e VAN ANDEL RESEARCH INSTITUTE   (United States)

Author keywords

Argonaute; gene silencing; GW182; miRNA; RNA interference; RNAi; TNRC6

Indexed keywords

ARGONAUTE PROTEIN; AUTOANTIGEN; AUTOANTIGEN GW182, HUMAN; EIF2C1 PROTEIN, HUMAN; GUIDE RNA; INITIATION FACTOR; MICRORNA; PROTEIN BINDING; RNA BINDING PROTEIN;

ANIMAL; BINDING COMPETITION; BINDING SITE; CHEMISTRY; CONFORMATION; GENE SILENCING; GENETIC TRANSFECTION; GENETICS; HUMAN; METABOLISM; MOLECULAR DOCKING; MUTATION; PROTEIN CONFORMATION; PROTEIN DOMAIN; SF9 CELL LINE; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

ANIMALS; ARGONAUTE PROTEINS; AUTOANTIGENS; BINDING SITES; BINDING, COMPETITIVE; CRYSTALLOGRAPHY, X-RAY; EUKARYOTIC INITIATION FACTORS; GENE SILENCING; HUMANS; MICRORNAS; MOLECULAR DOCKING SIMULATION; MUTATION; NUCLEIC ACID CONFORMATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN INTERACTION DOMAINS AND MOTIFS; RNA, GUIDE; RNA-BINDING PROTEINS; SF9 CELLS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

EID: 85027578183     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2017.07.007     Document Type: Article

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