A novel and organic solvent-free preparation of solid lipid nanoparticles using natural biopolymers as emulsifier and stabilizer

International Journal of Pharmaceutics

Volumn 531, Issue 1, 2017, Pages 59-66

  Xue, Jingyi ^a   Wang, Taoran ^a   Hu, Qiaobin ^a   Zhou, Mingyong ^a   Luo, Yangchao ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

Caseinate; Gastrointestinal stability; Nano spray drying; Organic solvent free; Pectin; Solid lipid nanoparticles

Indexed keywords

BIOPOLYMER; CASEIN; DRUG CARRIER; EMULSIFYING AGENT; LIPID; NANOPARTICLE; PECTIN; SOLVENT; STEARIC ACID; STEARIC ACID DERIVATIVE;

CHEMISTRY; MEDICINAL CHEMISTRY; PARTICLE SIZE;

BIOPOLYMERS; CASEINS; CHEMISTRY, PHARMACEUTICAL; DRUG CARRIERS; EMULSIFYING AGENTS; LIPIDS; NANOPARTICLES; PARTICLE SIZE; PECTINS; SOLVENTS; STEARIC ACIDS;

EID: 85027543379     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2017.08.066     Document Type: Article

References (42)

1. Ali, M.E., Lamprecht, A., Spray freeze drying for dry powder inhalation of nanoparticles. Eur. J. Pharm. Biopharm. 87 (2014), 510–517.
2. Baek, J.-S., So, J.-W., Shin, S.-C., Cho, C.-W., Solid lipid nanoparticles of paclitaxel strengthened by hydroxypropyl-β-cyclodextrin as an oral delivery system. Int. J. Mol. Med. 30 (2012), 953––959.
3. Bunjes, H., Koch, M.H., Westesen, K., Influence of emulsifiers on the crystallization of solid lipid nanoparticles. J. Pharm. Sci. 92 (2003), 1509––1520.
4. Chang, C., Wang, T., Hu, Q., Luo, Y., Zein/caseinate/pectin complex nanoparticles: formation and characterization. Int. J. Biol. Macromol. 104 (2017), 117––214.
5. Chaubal, M.V., Popescu, C., Conversion of nanosuspensions into dry powders by spray drying: a case study. Pharm. Res. 25 (2008), 2302––2308.
6. El Maghraby, G.M., Transdermal delivery of hydrocortisone from eucalyptus oil microemulsion: effects of cosurfactants. Int. J. Pharm. 355 (2008), 285––292.
7. Eltayeb, M., Bakhshi, P.K., Stride, E., Edirisinghe, M., Preparation of solid lipid nanoparticles containing active compound by electrohydrodynamic spraying. Food Res. Int. 53 (2013), 88–95.
8. Elversson, J., Millqvist-Fureby, A., Particle size and density in spray drying—effects of carbohydrate properties. J. Pharm. Sci. 94 (2005), 2049–2060.
9. Freitas, C., Müller, R.H., Spray-drying of solid lipid nanoparticles (SLNTM). Eur. J. Pharm. Biopharm. 46 (1998), 145––151.
10. Garcı́a-Fuentes, M., Torres, D., Alonso, M.J., Design of lipid nanoparticles for the oral delivery of hydrophilic macromolecules. Colloids Surf. B: Biointerfaces 27 (2003), 159–168.
11. Gnanasambandam, R., Proctor, A., Determination of pectin degree of esterification by diffuse reflectance Fourier transform infrared spectroscopy. Food Chem. 68 (2000), 327–332.
12. Hu, Q., Gerhard, H., Upadhyaya, I., Venkitanarayanan, K., Luo, Y., Antimicrobial eugenol nanoemulsion prepared by gum arabic and lecithin and evaluation of drying technologies. Int. J. Biol. Macromol. 87 (2016), 130–140.
13. Jollès, P., Alais, C., Jollès, J., Amino acid composition of κ-casein and terminal amino acids of κ- and para-κ-casein. Arch. Biochem. Biophys. 98 (1962), 56––57.
14. Jones, O.G., McClements, D.J., Recent progress in biopolymer nanoparticle and microparticle formation by heat-treating electrostatic protein–polysaccharide complexes. Adv. Colloid Interface Sci. 167 (2011), 49––62.
15. Jones, O.G., Decker, E.A., McClements, D.J., Formation of biopolymer particles by thermal treatment of β-lactoglobulin–pectin complexes. Food Hydrocoll. 23 (2009), 1312––1321.
16. Jones, O.G., Decker, E.A., McClements, D.J., Comparison of protein–polysaccharide nanoparticle fabrication methods: impact of biopolymer complexation before or after particle formation. J. Colloid Interface Sci. 344 (2010), 21–29.
17. Lee, S.H., Heng, D., Ng, W.K., Chan, H.-K., Tan, R.B., Nano spray drying: a novel method for preparing protein nanoparticles for protein therapy. Int. J. Pharm. 403 (2011), 192––200.
18. Li, X., Anton, N., Arpagaus, C., Belleteix, F., Vandamme, T.F., Nanoparticles by spray drying using innovative new technology: the Büchi nano spray dryer B-90. J. Control. Release 147 (2010), 304–310.
19. Liu, Y., Guo, R., pH-dependent structures and properties of casein micelles. Biophys. Chem. 136 (2008), 67–73.
20. Luo, Y., Pan, K., Zhong, Q., Casein/pectin nanocomplexes as potential oral delivery vehicles. Int. J. Pharm. 486 (2015), 59–68.
21. Luo, Y., Teng, Z., Li, Y., Wang, Q., Solid lipid nanoparticles for oral drug delivery: chitosan coating improves stability, controlled delivery, mucoadhesion and cellular uptake. Carbohydr. Polym. 120 (2015), 221–229.
22. Müller, R.H., Mäder, K., Gohla, S., Solid lipid nanoparticles (SLN) for controlled drug delivery −a review of the state of the art. Eur. J. Pharm. Biopharm. 50 (2000), 161––177.
23. McClements, D.J., Comments on viscosity enhancement and depletion flocculation by polysaccharides. Food Hydrocoll. 14 (2000), 173––177.
24. McClements, D.J., Protein-stabilized emulsions. Curr. Opin. Colloid Interface Sci. 9 (2004), 305––313.
25. Mehnert, W., Mäder, K., Solid lipid nanoparticles: production, characterization and applications. Adv. Drug Deliv. Rev. 47 (2001), 165––196.
26. Rahimi Yazdi, S., Corredig, M., Heating of milk alters the binding of curcumin to casein micelles: a fluorescence spectroscopy study. Food Chem. 132 (2012), 1143–1149.
27. Rediguieri, C.F., de Freitas, O., Lettinga, P., Tuinier, R., Thermodynamic incompatibility and complex formation in pectin/caseinate mixtures. Biomacromolecules 8 (2007), 3345–3354.
28. Roger, E., Lagarce, F., Benoit, J.P., The gastrointestinal stability of lipid nanocapsules. Int. J. Pharm. 379 (2009), 260––265.
29. Sahu, A., Kasoju, N., Bora, U., Fluorescence study of the curcumin- casein micelle complexation and its application as a drug nanocarrier to cancer cells. Biomacromolecules 9 (2008), 2905––2912.
30. Schöler, N., Olbrich, C., Tabatt, K., Müller, R.H., Hahn, H., Liesenfeld, O., Surfactant, but not the size of solid lipid nanoparticles (SLN) influences viability and cytokine production of macrophages. Int. J. Pharm. 221 (2001), 57–67.
31. Shahgaldian, P., Gualbert, J., Aı̈ssa, K.s., Coleman, A.W., A study of the freeze-drying conditions of calixarene based solid lipid nanoparticles. Eur. J. Pharm. Biopharm. 55 (2003), 181–184.
32. Teng, Z., Li, Y., Luo, Y., Zhang, B., Wang, Q., Cationic β-lactoglobulin nanoparticles as a bioavailability enhancer: protein characterization and particle formation. Biomacromolecules 14 (2013), 2848––2856.
33. Tiyaboonchai, W., Tungpradit, W., Plianbangchang, P., Formulation and characterization of curcuminoids loaded solid lipid nanoparticles. Int. J. Pharm. 337 (2007), 299–306.
34. Wang, T., Hu, Q., Zhou, M., Xia, Y., Nieh, M.-P., Luo, Y., Development of all natural layer-by-layer redispersible solid lipid nanoparticles by nano spray drying technology. Eur. J. Pharm. Biopharm. 107 (2016), 273–285.
35. Wang, T., Hu, Q., Zhou, M., Xue, J., Luo, Y., Preparation of ultra-fine powders from polysaccharide-coated solid lipid nanoparticles and nanostructured lipid carriers by innovative nano spray drying technology. Int. J. Pharm. 511 (2016), 219–222.
36. Wang, T., Ma, X., Lei, Y., Luo, Y., Solid lipid nanoparticles coated with cross-linked polymeric double layer for oral delivery of curcumin. Colloids Surf. B: Biointerfaces 148 (2016), 1–11.
37. Wang, T., Xue, J., Hu, Q., Zhou, M., Chang, C., Luo, Y., Synthetic surfactant- and cross-linker-free prepration of highly stable lipid-polymer hybrid nanoparticles as potential oral delivery vehicles. Sci. Rep., 7, 2017, 2750.
38. Zhang, X., Pan, W., Gan, L., Zhu, C., Gan, Y., Nie, S., Preparation of a dispersible PEGylate nanostructured lipid carriers (NLC) loaded with 10-hydroxycamptothecin by spray-drying. Chem. Pharm. Bull. 56 (2008), 1645––1650.
39. Zhang, Y., Li, J.-H., Ge, Y.-S., Liu, X.-R., Jiang, F.-L., Liu, Y., Biophysical studies on the interactions of a classic mitochondrial uncoupler with bovine serum albumin by spectroscopic, isothermal titration calorimetric and molecular modeling methods. J. Fluoresc. 21 (2011), 475–485.
40. Zhang, J., Liu, Y., Liu, X., Li, Y., Yin, X., Subirade, M., Zhou, P., Liang, L., The folic acid/β-casein complex: characteristics and physicochemical implications. Food Res. Int. 57 (2014), 162–167.
41. Zhou, M., Wang, T., Hu, Q., Luo, Y., Low density lipoprotein/pectin complex nanogels as potential oral delivery vehicles for curcumin. Food Hydrocoll. 57 (2016), 20–29.
42. Zimmermann, E., Müller, R.H., Electrolyte- and pH-stabilities of aqueous solid lipid nanoparticle (SLN™) dispersions in artificial gastrointestinal media. Eur. J. Pharm. Biopharm. 52 (2001), 203–210.