Zika plasma viral dynamics in nonhuman primates provides insights into early infection and antiviral strategies

Proceedings of the National Academy of Sciences of the United States of America

Volumn 114, Issue 33, 2017, Pages 8847-8852

  Best, Katharine ^a   Guedj, Jeremie ^b   Madelain, Vincent ^b   De Lamballerie, Xavier ^c   Lim, So Yon ^d   Osuna, Christa E ^d   Whitney, James B ^d,e   Perelson, Alan S ^a  

^a LOS ALAMOS NATIONAL LABORATORY   (United States)

^b UNIVERSITÉ PARIS DIDEROT   (France)

^c Aix Marseille University IRD 190 Inserm 1207   (France)

^d HARVARD MEDICAL SCHOOL   (United States)

^e MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Antiviral therapy; Mathematical modeling; Viral dynamics; Zika virus

Indexed keywords

FAVIPIRAVIR; ANTIVIRUS AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIVIRAL THERAPY; ARTICLE; DRUG CONCENTRATION; EC50; FEMALE; IMMUNE RESPONSE; KINETICS; MALE; MATHEMATICAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; RHESUS MONKEY; VIRAL CLEARANCE; VIRION; VIROGENESIS; VIRUS LOAD; VIRUS REPLICATION; ZIKA FEVER; ZIKA VIRUS; ANIMAL; BIOLOGICAL MODEL; BLOOD; DRUG EFFECT; PHYSIOLOGY;

ANIMALS; ANTIVIRAL AGENTS; MACACA MULATTA; MODELS, BIOLOGICAL; VIRAL LOAD; VIRUS REPLICATION; ZIKA VIRUS; ZIKA VIRUS INFECTION;

EID: 85027414344     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1704011114     Document Type: Article

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