-
1
-
-
79958717571
-
The global health burden of hepatitis C virus infection
-
Negro F, Alberti A. The global health burden of hepatitis C virus infection. Liver Int 2011;31(Suppl 2):1-3.
-
(2011)
Liver Int
, vol.31
, Issue.2 SUPPL
, pp. 1-3
-
-
Negro, F.1
Alberti, A.2
-
2
-
-
33748114343
-
The contributions of hepatitis B virus and hepatitis C virus infections to cirrhosis and primary liver cancer worldwide
-
Perz JF, Armstrong GL, Farrington LA, Hutin YJF, Bell BP. The contributions of hepatitis B virus and hepatitis C virus infections to cirrhosis and primary liver cancer worldwide. J Hepatol 2006;45:529-538.
-
(2006)
J Hepatol
, vol.45
, pp. 529-538
-
-
Perz, J.F.1
Armstrong, G.L.2
Farrington, L.A.3
Hutin, Y.J.F.4
Bell, B.P.5
-
3
-
-
79953173221
-
Boceprevir for untreated chronic HCV genotype 1 infection
-
Poordad F, McCone J, Jr., Bacon BR, Bruno S, Manns MP, Sulkowski MS, et al. Boceprevir for untreated chronic HCV genotype 1 infection. N Engl J Med 2011;364:1195-1206.
-
(2011)
N Engl J Med
, vol.364
, pp. 1195-1206
-
-
Poordad, F.1
McCone Jr, J.2
Bacon, B.R.3
Bruno, S.4
Manns, M.P.5
Sulkowski, M.S.6
-
4
-
-
80755159054
-
Discovery and development of telaprevir: an NS3-4A protease inhibitor for treating genotype 1 chronic hepatitis C virus
-
Kwong AD, Kauffman RS, Hurter P, Mueller P. Discovery and development of telaprevir: an NS3-4A protease inhibitor for treating genotype 1 chronic hepatitis C virus. Nat Biotechnol 2011;29:993-1003.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 993-1003
-
-
Kwong, A.D.1
Kauffman, R.S.2
Hurter, P.3
Mueller, P.4
-
5
-
-
80052116134
-
Telaprevir alone or with peginterferon and ribavirin reduces HCV RNA in patients with chronic genotype 2 but not genotype 3 infections
-
Foster GR, Hézode C, Bronowicki JP, Carosi G, Weiland O, Verlinden L, et al. Telaprevir alone or with peginterferon and ribavirin reduces HCV RNA in patients with chronic genotype 2 but not genotype 3 infections. Gastroenterology 2011;141:881-889.
-
(2011)
Gastroenterology
, vol.141
, pp. 881-889
-
-
Foster, G.R.1
Hézode, C.2
Bronowicki, J.P.3
Carosi, G.4
Weiland, O.5
Verlinden, L.6
-
6
-
-
84864281382
-
Cyclophilin inhibitors: a novel class of promising host-targeting anti-HCV agents
-
Gallay PA. Cyclophilin inhibitors: a novel class of promising host-targeting anti-HCV agents. Immunol Res 2012;52:200-210.
-
(2012)
Immunol Res
, vol.52
, pp. 200-210
-
-
Gallay, P.A.1
-
7
-
-
84873978406
-
Profile of alisporivir and its potential in the treatment of hepatitis C
-
Gallay PA, Lin K. Profile of alisporivir and its potential in the treatment of hepatitis C. Drug Des Devel Ther 2013;7:105-115.
-
(2013)
Drug Des Devel Ther
, vol.7
, pp. 105-115
-
-
Gallay, P.A.1
Lin, K.2
-
8
-
-
78149434641
-
DEB025 (Alisporivir) inhibits hepatitis C virus replication by preventing a cyclophilin A induced cis-trans isomerisation in domain II of NS5A
-
Coelmont L, Hanoulle X, Chatterji U, Berger C, Snoeck J, Bobardt M, et al. DEB025 (Alisporivir) inhibits hepatitis C virus replication by preventing a cyclophilin A induced cis-trans isomerisation in domain II of NS5A. PLoS One 2010;5:e13687.
-
(2010)
PLoS One
, vol.5
-
-
Coelmont, L.1
Hanoulle, X.2
Chatterji, U.3
Berger, C.4
Snoeck, J.5
Bobardt, M.6
-
9
-
-
84866309587
-
Multiple mutations in hepatitis C virus NS5A domain II are required to confer a significant level of resistance to alisporivir
-
Garcia-Rivera JA, Bobardt M, Chatterji U, Hopkins S, Gregory MA, Lin K, et al. Multiple mutations in hepatitis C virus NS5A domain II are required to confer a significant level of resistance to alisporivir. Antimicrob Agents Chemother 2012;56:5113-5121.
-
(2012)
Antimicrob Agents Chemother
, vol.56
, pp. 5113-5121
-
-
Garcia-Rivera, J.A.1
Bobardt, M.2
Chatterji, U.3
Hopkins, S.4
Gregory, M.A.5
Lin, K.6
-
10
-
-
85081455893
-
-
Cambridge MA, Abstract R14.
-
Tiongyip C, Jones CT, Tang Y, Snoeck J, Vandamme A, Coelmont L, et al. The host targeting cyclophilin inhibitor alisporivir presents a high barrier to resistance with no cross-resistance to direct acting antivirals. The 6th International Workshop on Hepatitis C Resistance and New Compounds, Cambridge MA, 2011, Abstract R14.
-
(2011)
The host targeting cyclophilin inhibitor alisporivir presents a high barrier to resistance with no cross-resistance to direct acting antivirals. The 6th International Workshop on Hepatitis C Resistance and New Compounds
-
-
Tiongyip, C.1
Jones, C.T.2
Tang, Y.3
Snoeck, J.4
Vandamme, A.5
Coelmont, L.6
-
11
-
-
84863704212
-
Alisporivir plus ribavirin is highly effective as interferon-free or interferon-add-on regimen in previously untreated HCV-GT2 or GT3 patients: SVR12 results from VITAL-1 Phase 2b Study
-
Pawlotsky J, Sarin S, Foster G, Peng C, Rasenack J, Flisiak R, et al. Alisporivir plus ribavirin is highly effective as interferon-free or interferon-add-on regimen in previously untreated HCV-GT2 or GT3 patients: SVR12 results from VITAL-1 Phase 2b Study. J Hepatol 2012;56:S553.
-
(2012)
J Hepatol
, vol.56
-
-
Pawlotsky, J.1
Sarin, S.2
Foster, G.3
Peng, C.4
Rasenack, J.5
Flisiak, R.6
-
12
-
-
84867267890
-
Mathematical modelling of HCV infection: what can it teach us in the era of direct-acting antiviral agents?
-
Chatterjee A, Guedj J, Perelson AS. Mathematical modelling of HCV infection: what can it teach us in the era of direct-acting antiviral agents? Antivir Ther 2012;17:1171-1182.
-
(2012)
Antivir Ther
, vol.17
, pp. 1171-1182
-
-
Chatterjee, A.1
Guedj, J.2
Perelson, A.S.3
-
13
-
-
0032475822
-
Hepatitis C viral dynamics in vivo and the antiviral efficacy of interferon-α therapy
-
Neumann AU, Lam NP, Dahari H, Gretch DR, Wiley TE, Layden TJ, Perelson AS. Hepatitis C viral dynamics in vivo and the antiviral efficacy of interferon-α therapy. Science 1998;282:103-107.
-
(1998)
Science
, vol.282
, pp. 103-107
-
-
Neumann, A.U.1
Lam, N.P.2
Dahari, H.3
Gretch, D.R.4
Wiley, T.E.5
Layden, T.J.6
Perelson, A.S.7
-
14
-
-
0020315441
-
Kinetics of pharmacologic response
-
Holford NH, Sheiner LB. Kinetics of pharmacologic response. Pharmacol Ther 1982;16:143-166.
-
(1982)
Pharmacol Ther
, vol.16
, pp. 143-166
-
-
Holford, N.H.1
Sheiner, L.B.2
-
15
-
-
35648934561
-
Maximum likelihood estimation in dynamical models of HIV
-
Guedj J, Thiébaut R, Commenges D. Maximum likelihood estimation in dynamical models of HIV. Biometrics 2007;63:1198-1206.
-
(2007)
Biometrics
, vol.63
, pp. 1198-1206
-
-
Guedj, J.1
Thiébaut, R.2
Commenges, D.3
-
16
-
-
0000120766
-
Estimating the dimension of a model
-
Schwarz G. Estimating the dimension of a model. Annals Statist 1978;6:461-464.
-
(1978)
Annals Statist
, vol.6
, pp. 461-464
-
-
Schwarz, G.1
-
17
-
-
11144330097
-
Modelling how ribavirin improves interferon response rates in hepatitis C virus infection
-
Dixit NM, Layden-Almer JE, Layden TJ, Perelson AS. Modelling how ribavirin improves interferon response rates in hepatitis C virus infection. Nature 2004;432:922-924.
-
(2004)
Nature
, vol.432
, pp. 922-924
-
-
Dixit, N.M.1
Layden-Almer, J.E.2
Layden, T.J.3
Perelson, A.S.4
-
18
-
-
79957448889
-
Second-phase hepatitis C virus RNA decline during telaprevir-based therapy increases with drug effectiveness: implications for treatment duration
-
Guedj J, Perelson AS. Second-phase hepatitis C virus RNA decline during telaprevir-based therapy increases with drug effectiveness: implications for treatment duration. Hepatology 2011;53:1801-1808.
-
(2011)
Hepatology
, vol.53
, pp. 1801-1808
-
-
Guedj, J.1
Perelson, A.S.2
-
19
-
-
0033914625
-
Differences in viral dynamics between genotypes 1 and 2 of hepatitis C virus
-
Neumann AU, Lam NP, Dahari H, Davidian M, Wiley TE, Mika BP, et al. Differences in viral dynamics between genotypes 1 and 2 of hepatitis C virus. J Infect Dis 2000;182:28-35.
-
(2000)
J Infect Dis
, vol.182
, pp. 28-35
-
-
Neumann, A.U.1
Lam, N.P.2
Dahari, H.3
Davidian, M.4
Wiley, T.E.5
Mika, B.P.6
-
20
-
-
84863396230
-
Hepatitis C viral kinetics with the nucleoside polymerase inhibitor mericitabine (RG7128)
-
Guedj J, Dahari H, Shudo E, Smith P, Perelson AS. Hepatitis C viral kinetics with the nucleoside polymerase inhibitor mericitabine (RG7128). Hepatology 2012;55:1030-1037.
-
(2012)
Hepatology
, vol.55
, pp. 1030-1037
-
-
Guedj, J.1
Dahari, H.2
Shudo, E.3
Smith, P.4
Perelson, A.S.5
-
21
-
-
84888862562
-
Interferon (IFN)-free alisporivir (ALV) has a better overall safety profile compared to IFN-containing treatment: a pooled analysis of the ALV development program
-
Griffel L, Bao W, Orsenigo R, Guo V, Wu M, Loeffler J, et al. Interferon (IFN)-free alisporivir (ALV) has a better overall safety profile compared to IFN-containing treatment: a pooled analysis of the ALV development program. J Hepatol 2013;58:S336-S337.
-
(2013)
J Hepatol
, vol.58
-
-
Griffel, L.1
Bao, W.2
Orsenigo, R.3
Guo, V.4
Wu, M.5
Loeffler, J.6
-
22
-
-
77951046665
-
HCV resistance to cyclosporin A does not correlate with a resistance of the NS5A-cyclophilin A interaction to cyclophilin inhibitors
-
Chatterji U, Lim P, Bobardt MD, Wieland S, Cordek DG, Vuagniaux G, et al. HCV resistance to cyclosporin A does not correlate with a resistance of the NS5A-cyclophilin A interaction to cyclophilin inhibitors. J Hepatol 2010;53:50-56.
-
(2010)
J Hepatol
, vol.53
, pp. 50-56
-
-
Chatterji, U.1
Lim, P.2
Bobardt, M.D.3
Wieland, S.4
Cordek, D.G.5
Vuagniaux, G.6
|