Modelling Virus and Antibody Dynamics during Dengue Virus Infection Suggests a Role for Antibody in Virus Clearance

PLoS Computational Biology

Volumn 12, Issue 5, 2016, Pages

  Clapham, Hannah E ^a   Quyen, Than Ha ^b   Kien, Duong Thi Hue ^b   Dorigatti, Ilaria ^a   Simmons, Cameron P ^b,c,d   Ferguson, Neil M ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b OXFORD UNIVERSITY CLINICAL RESEARCH UNIT   (Viet Nam)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUSES;

DENGUE VIRUS; HOST IMMUNE RESPONSE; MECHANISTICS; MODEL FIT; NATURAL INFECTION; UNCERTAINTY; VIETNAMESE; VIRAL REPLICATION; VIRUS CLEARANCE; VIRUS INFECTION;

ANTIBODIES;

ANTIBODY; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; IMMUNOGLOBULIN M ANTIBODY; NEUTRALIZING ANTIBODY; VIRUS ANTIBODY; VIRUS RNA;

ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY; ANTIBODY TITER; ARTICLE; CONTROLLED STUDY; DENGUE; DENGUE VIRUS 1; DENGUE VIRUS 2; HUMAN; IMMUNE RESPONSE; IMMUNOREGULATION; MAJOR CLINICAL STUDY; MATHEMATICAL MODEL; VIETNAMESE; VIRAL CLEARANCE; VIRUS NEUTRALIZATION; VIRUS REPLICATION; BIOLOGICAL MODEL; BIOLOGY; BLOOD; DENGUE VIRUS; HOST PATHOGEN INTERACTION; IMMUNOLOGY; KINETICS; PHYSIOLOGY; VIROLOGY; VIRUS LOAD;

ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; ANTIBODY-DEPENDENT CELL CYTOTOXICITY; COMPUTATIONAL BIOLOGY; DENGUE; DENGUE VIRUS; HOST-PATHOGEN INTERACTIONS; HUMANS; KINETICS; MODELS, BIOLOGICAL; MODELS, IMMUNOLOGICAL; RNA, VIRAL; VIRAL LOAD; VIRUS REPLICATION;

EID: 84975879841     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1004951     Document Type: Article

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