Mechanical behavior and matrisome gene expression in the aneurysm-prone thoracic aorta of newborn lysyl oxidase knockout mice

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 313, Issue 2, 2017, Pages H446-H456

  Staiculescu, Marius Catalin ^a   Kim, Jungsil ^a   Mecham, Robert P ^b   Wagenseil, Jessica E ^a  

^a WASHINGTON UNIVERSITY IN ST LOUIS   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aneurysm; Collagen; Dissection; Elastin; Gene array; Matrisome; Mechanics; Tortuosity

Indexed keywords

BETA 2 MICROGLOBULIN; COLLAGEN; CYCLIN DEPENDENT KINASE INHIBITOR 1B; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE 1; PROTEIN LYSINE 6 OXIDASE; PROTEOGLYCAN; UNCLASSIFIED DRUG; ELASTIN; LOX PROTEIN, MOUSE; SCLEROPROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASCENDING AORTA; BLOOD PRESSURE MEASUREMENT; CELL PROLIFERATION; CROSS LINKING; DESCENDING AORTA; EXTRACELLULAR MATRIX; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; GENOTYPE; KNOCKOUT MOUSE; MECHANICAL STIMULUS TEST; MORPHOLOGY; MOUSE; MYOGRAPHY; NEWBORN; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMOOTH MUSCLE CELL; THORACIC AORTA ANEURYSM; UPREGULATION; ANIMAL; ARTERIAL PRESSURE; ARTERIAL STIFFNESS; BIOMECHANICS; DISEASE MODEL; ENZYMOLOGY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION; GENETICS; LESIONS AND DEFECTS; MECHANICAL STRESS; MECHANOTRANSDUCTION; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; THORACIC AORTA;

ANIMALS; ANIMALS, NEWBORN; AORTA, THORACIC; AORTIC ANEURYSM, THORACIC; ARTERIAL PRESSURE; BIOMECHANICAL PHENOMENA; COLLAGEN; DILATATION, PATHOLOGIC; DISEASE MODELS, ANIMAL; ELASTIN; EXTRACELLULAR MATRIX PROTEINS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; MECHANOTRANSDUCTION, CELLULAR; MICE, KNOCKOUT; PHENOTYPE; PROTEIN-LYSINE 6-OXIDASE; STRESS, MECHANICAL; VASCULAR STIFFNESS;

EID: 85027244631     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00712.2016     Document Type: Article

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