Allicin ameliorates doxorubicin-induced cardiotoxicity in rats via suppression of oxidative stress, inflammation and apoptosis

Cancer Chemotherapy and Pharmacology

Volumn 80, Issue 4, 2017, Pages 745-753

  Abdel Daim, Mohamed M ^a   kilany, Omnia E ^a   Khalifa, Hesham A ^b   Ahmed, Amal A M ^a  

^a Suez Canal University   (Egypt)

^b Zagazig University   (Egypt)

Author keywords

Adriamycin; Anti inflammatory; Antioxidant; Apoptosis; Cardiotoxicity; Garlic; Heart; Inflammation; Oxidative damage

Indexed keywords

ALLICIN; ASPARTATE AMINOTRANSFERASE; BIOLOGICAL MARKER; CASPASE 3; CATALASE; CREATINE KINASE; CREATINE KINASE MB; CYCLOOXYGENASE 2; DOXORUBICIN; GLUTATHIONE; GLUTATHIONE PEROXIDASE; INTERLEUKIN 1BETA; LACTATE DEHYDROGENASE; MALONALDEHYDE; NITRIC OXIDE; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR; ANTINEOPLASTIC ANTIBIOTIC; ANTIOXIDANT; CYTOKINE; SULFINIC ACID DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CARDIOTOXICITY; CONTROLLED STUDY; CREATINE KINASE BLOOD LEVEL; DRUG EFFECT; DRUG SCREENING; ENZYME ACTIVATION; HEART TISSUE; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LACTATE DEHYDROGENASE BLOOD LEVEL; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RAT; ANIMAL; BLOOD; CHEMICALLY INDUCED; DOSE RESPONSE; DRUG EFFECTS; INFLAMMATION; METABOLISM;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; ANTIOXIDANTS; APOPTOSIS; BIOMARKERS; CARDIOTOXICITY; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; INFLAMMATION; MALE; MALONDIALDEHYDE; MICE; NITRIC OXIDE; OXIDATIVE STRESS; SULFINIC ACIDS;

EID: 85026904784     PISSN: 03445704     EISSN: 14320843     Source Type: Journal    
DOI: 10.1007/s00280-017-3413-7     Document Type: Article

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