Downregulation of doxorubicin-induced myocardial apoptosis accompanies postnatal heart maturation

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 302, Issue 8, 2012, Pages

  Shi, Jianjian ^a   Zhang, Lumin ^a   Zhang, Yi Wei ^a   Surma, Michelle ^a   Mark Payne, R ^a,b   Wei, Lei ^a,b  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b INDIANA UNIVERSITY   (United States)

Author keywords

Anthracycline; Cardiomyocyte; Cardiotoxicity; Caspase; Chemotherapy

Indexed keywords

BENZYLOXYCARBONYLISOLEUCYLGLUTAMYLTHREONYLASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLLEUCYLGLUTAMYLHISTIDYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3; CASPASE 8; CASPASE 9; CATHEPSIN B INHIBITOR; DOXORUBICIN; PEPSTATIN;

AGE; ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARDIOTOXICITY; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; HEART MUSCLE; HEART MUSCLE CELL; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MOUSE; NICK END LABELING; NONHUMAN; ORGANOGENESIS; POSTNATAL HEART MATURATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; SINGLE DRUG DOSE;

ANIMALS; ANIMALS, NEWBORN; ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CASPASES; DOWN-REGULATION; DOXORUBICIN; ENZYME ACTIVATION; HEART; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; LAC OPERON; MICE; MICE, TRANSGENIC; MITOCHONDRIA, HEART; MYOCARDIUM; MYOCYTES, CARDIAC; SIGNAL TRANSDUCTION; SUBCELLULAR FRACTIONS;

EID: 84859744074     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00844.2011     Document Type: Article

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