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Volumn 22, Issue 10, 2017, Pages 1246-1259

Novel combination of salinomycin and resveratrol synergistically enhances the anti-proliferative and pro-apoptotic effects on human breast cancer cells

Author keywords

Apoptosis; Breast cancer; MAPK; Resveratrol; Salinomycin; Synergism

Indexed keywords

CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; MANGANESE SUPEROXIDE DISMUTASE; REACTIVE OXYGEN METABOLITE; RESVERATROL; SALINOMYCIN; SUPEROXIDE DISMUTASE; ANTINEOPLASTIC AGENT; PYRAN DERIVATIVE; STILBENE DERIVATIVE;

EID: 85026896335     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-017-1394-y     Document Type: Article
Times cited : (58)

References (43)
  • 2
    • 84899463978 scopus 로고    scopus 로고
    • Resveratrol and cancer: focus on in vivo evidence
    • COI: 1:CAS:528:DC%2BC2cXhtlOmsbrO
    • Carter LG, D’Orazio JA, Pearson KJ. (2014) Resveratrol and cancer: focus on in vivo evidence. Endocr Related Cancer 21:R209–R225
    • (2014) Endocr Related Cancer , vol.21 , pp. R209-R225
    • Carter, L.G.1    D’Orazio, J.A.2    Pearson, K.J.3
  • 3
    • 84877814639 scopus 로고    scopus 로고
    • Treating breast cancer in the 21st century: emerging biological therapies
    • PID: 23386910
    • Tinoco G, Warsch S, Gluck S, Avancha K, Montero AJ (2013) Treating breast cancer in the 21st century: emerging biological therapies. J Cancer 4:117–132
    • (2013) J Cancer , vol.4 , pp. 117-132
    • Tinoco, G.1    Warsch, S.2    Gluck, S.3    Avancha, K.4    Montero, A.J.5
  • 4
    • 80053426842 scopus 로고    scopus 로고
    • Targeted therapies for breast cancer
    • COI: 1:CAS:528:DC%2BC3MXht12ht7vJ, PID: 21965336
    • Higgins MJ, Baselga J (2011) Targeted therapies for breast cancer. J Clin Invest 121:3797–3803
    • (2011) J Clin Invest , vol.121 , pp. 3797-3803
    • Higgins, M.J.1    Baselga, J.2
  • 5
    • 0027218689 scopus 로고
    • Biochemistry of multidrug resistance mediated by the multidrug transporter
    • COI: 1:CAS:528:DyaK3sXlsFWnsbY%3D, PID: 8102521
    • Gottesman MM, Pastan I (1993) Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu Rev Biochem 62:385–427
    • (1993) Annu Rev Biochem , vol.62 , pp. 385-427
    • Gottesman, M.M.1    Pastan, I.2
  • 6
    • 84908388798 scopus 로고    scopus 로고
    • A breast cancer stem cell-selective, mammospheres-potent osmium(VI) nitrido complex
    • COI: 1:CAS:528:DC%2BC2cXhsFyrsLzK, PID: 25247635
    • Suntharalingam K, Lin W, Johnstone TC et al (2014) A breast cancer stem cell-selective, mammospheres-potent osmium(VI) nitrido complex. J Am Chem Soc 136:14413–14416
    • (2014) J Am Chem Soc , vol.136 , pp. 14413-14416
    • Suntharalingam, K.1    Lin, W.2    Johnstone, T.C.3
  • 7
    • 84871142437 scopus 로고    scopus 로고
    • A new prospect in cancer therapy: targeting cancer stem cells to eradicate cancer. Chinese
    • COI: 1:CAS:528:DC%2BC3sXivFWhsbk%3D
    • Chen LS, Wang AX, Dong B, Pu KF, Yuan LH, Zhu YM (2012) A new prospect in cancer therapy: targeting cancer stem cells to eradicate cancer. Chinese. J Cancer 31:564–572
    • (2012) J Cancer , vol.31 , pp. 564-572
    • Chen, L.S.1    Wang, A.X.2    Dong, B.3    Pu, K.F.4    Yuan, L.H.5    Zhu, Y.M.6
  • 8
    • 84882686716 scopus 로고    scopus 로고
    • Salinomycin induces activation of autophagy, mitophagy and affects mitochondrial polarity: differences between primary and cancer cells
    • COI: 1:CAS:528:DC%2BC3sXptFKrsrg%3D, PID: 23639289
    • Jangamreddy JR, Ghavami S, Grabarek J et al (2013) Salinomycin induces activation of autophagy, mitophagy and affects mitochondrial polarity: differences between primary and cancer cells. Biochim Biophys Acta 1833:2057–2069
    • (2013) Biochim Biophys Acta , vol.1833 , pp. 2057-2069
    • Jangamreddy, J.R.1    Ghavami, S.2    Grabarek, J.3
  • 9
    • 70449724577 scopus 로고    scopus 로고
    • Salinomycin induces apoptosis and overcomes apoptosis resistance in human cancer cells
    • COI: 1:CAS:528:DC%2BD1MXhsVKgtbbN, PID: 19835841
    • Fuchs D, Heinold A, Opelz G, Daniel V, Naujokat C (2009) Salinomycin induces apoptosis and overcomes apoptosis resistance in human cancer cells. Biochem Biophys Res Commun 390:743–749
    • (2009) Biochem Biophys Res Commun , vol.390 , pp. 743-749
    • Fuchs, D.1    Heinold, A.2    Opelz, G.3    Daniel, V.4    Naujokat, C.5
  • 11
    • 84855396578 scopus 로고    scopus 로고
    • Salinomycin inhibits prostate cancer growth and migration via induction of oxidative stress
    • COI: 1:CAS:528:DC%2BC38XktFCntA%3D%3D, PID: 22215106
    • Ketola K, Hilvo M, Hyotylainen T et al (2012) Salinomycin inhibits prostate cancer growth and migration via induction of oxidative stress. Br J Cancer 106:99–106
    • (2012) Br J Cancer , vol.106 , pp. 99-106
    • Ketola, K.1    Hilvo, M.2    Hyotylainen, T.3
  • 12
    • 84871401029 scopus 로고    scopus 로고
    • Salinomycin inhibits proliferation and induces apoptosis of human hepatocellular carcinoma cells in vitro and in vivo
    • COI: 1:CAS:528:DC%2BC3sXksVyrtg%3D%3D, PID: 23284640
    • Wang F, He L, Dai WQ et al (2012) Salinomycin inhibits proliferation and induces apoptosis of human hepatocellular carcinoma cells in vitro and in vivo. PLoS ONE 7:e50638
    • (2012) PLoS ONE , vol.7
    • Wang, F.1    He, L.2    Dai, W.Q.3
  • 13
    • 84887963510 scopus 로고    scopus 로고
    • Salinomycin: a novel anti-cancer agent with known anti-coccidial activities
    • COI: 1:CAS:528:DC%2BC3sXhsFymsrbF, PID: 23931281
    • Zhou S, Wang F, Wong ET et al (2013) Salinomycin: a novel anti-cancer agent with known anti-coccidial activities. Curr Med Chem 20:4095–4101
    • (2013) Curr Med Chem , vol.20 , pp. 4095-4101
    • Zhou, S.1    Wang, F.2    Wong, E.T.3
  • 14
    • 68749099671 scopus 로고    scopus 로고
    • Identification of selective inhibitors of cancer stem cells by high-throughput screening
    • COI: 1:CAS:528:DC%2BD1MXhsVCjs73E, PID: 19682730
    • Gupta PB, Onder TT, Jiang G et al (2009) Identification of selective inhibitors of cancer stem cells by high-throughput screening. Cell 138:645–659
    • (2009) Cell , vol.138 , pp. 645-659
    • Gupta, P.B.1    Onder, T.T.2    Jiang, G.3
  • 15
    • 85016924820 scopus 로고    scopus 로고
    • Salinomycin: a new paradigm in cancer therapy
    • PID: 28349817
    • Dewangan J, Srivastava S, Rath SK (2017) Salinomycin: a new paradigm in cancer therapy. Tumour Biol 39:1010428317695035
    • (2017) Tumour Biol , vol.39
    • Dewangan, J.1    Srivastava, S.2    Rath, S.K.3
  • 16
    • 84879696870 scopus 로고    scopus 로고
    • Dose-dependent adverse effects of salinomycin on male reproductive organs and fertility in mice
    • COI: 1:CAS:528:DC%2BC3sXhtFersLbK, PID: 23840907
    • Ojo OO, Bhadauria S, Rath SK (2013) Dose-dependent adverse effects of salinomycin on male reproductive organs and fertility in mice. PLoS ONE 8:e69086
    • (2013) PLoS ONE , vol.8
    • Ojo, O.O.1    Bhadauria, S.2    Rath, S.K.3
  • 19
    • 0034645693 scopus 로고    scopus 로고
    • Biological effects of resveratrol
    • COI: 1:CAS:528:DC%2BD3cXntF2jtw%3D%3D, PID: 10680575
    • Fremont L (2000) Biological effects of resveratrol. Life Sci 66:663–673
    • (2000) Life Sci , vol.66 , pp. 663-673
    • Fremont, L.1
  • 20
    • 33745962138 scopus 로고    scopus 로고
    • Therapeutic potential of resveratrol: the in vivo evidence
    • COI: 1:CAS:528:DC%2BD28XlsV2jur8%3D, PID: 16732220
    • Baur JA, Sinclair DA. (2006) Therapeutic potential of resveratrol: the in vivo evidence. Nat Rev Drug Discov 5:493–506
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 493-506
    • Baur, J.A.1    Sinclair, D.A.2
  • 21
    • 84864695182 scopus 로고    scopus 로고
    • Alternaria sp. MG1, a resveratrol-producing fungus: isolation, identification, and optimal cultivation conditions for resveratrol production
    • COI: 1:CAS:528:DC%2BC38XotlSlu7w%3D, PID: 22526800
    • Shi J, Zeng Q, Liu Y, Pan Z (2012) Alternaria sp. MG1, a resveratrol-producing fungus: isolation, identification, and optimal cultivation conditions for resveratrol production. Appl Microbiol Biotechnol 95:369–379
    • (2012) Appl Microbiol Biotechnol , vol.95 , pp. 369-379
    • Shi, J.1    Zeng, Q.2    Liu, Y.3    Pan, Z.4
  • 22
    • 3542996841 scopus 로고    scopus 로고
    • Resveratrol inhibits cyclooxygenase-2 transcription and activity in phorbol ester-treated human mammary epithelial cells
    • COI: 1:CAS:528:DyaK1cXlsFOqsb0%3D, PID: 9705326
    • Subbaramaiah K, Chung WJ, Michaluart P et al (1998) Resveratrol inhibits cyclooxygenase-2 transcription and activity in phorbol ester-treated human mammary epithelial cells. J Biol Chem 273:21875–21882
    • (1998) J Biol Chem , vol.273 , pp. 21875-21882
    • Subbaramaiah, K.1    Chung, W.J.2    Michaluart, P.3
  • 25
    • 33748794547 scopus 로고    scopus 로고
    • Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies
    • COI: 1:CAS:528:DC%2BD28XhtVOhtLfL, PID: 16968952
    • Chou TC (2006) Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies. Pharmacol Rev 58:621–681
    • (2006) Pharmacol Rev , vol.58 , pp. 621-681
    • Chou, T.C.1
  • 26
    • 84860992007 scopus 로고    scopus 로고
    • Choosing the right cell line for breast cancer research
    • PID: 21884641
    • Holliday DL, Speirs V. (2011) Choosing the right cell line for breast cancer research. Breast Cancer Res 13:215
    • (2011) Breast Cancer Res , vol.13 , pp. 215
    • Holliday, D.L.1    Speirs, V.2
  • 27
    • 0019882480 scopus 로고
    • Generalized equations for the analysis of inhibitions of Michaelis–Menten and higher-order kinetic systems with two or more mutually exclusive and nonexclusive inhibitors
    • COI: 1:CAS:528:DyaL3MXhtlCqsbk%3D
    • Chou TC, Talalay P (1981) Generalized equations for the analysis of inhibitions of Michaelis–Menten and higher-order kinetic systems with two or more mutually exclusive and nonexclusive inhibitors. European journal of biochemistry/FEBS 115:207–216
    • (1981) European journal of biochemistry/FEBS , vol.115 , pp. 207-216
    • Chou, T.C.1    Talalay, P.2
  • 28
    • 0021118703 scopus 로고
    • Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors
    • COI: 1:CAS:528:DyaL2cXktlaksLk%3D, PID: 6382953
    • Chou TC, Talalay P (1984) Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. Adv Enzyme Regul 22:27–55
    • (1984) Adv Enzyme Regul , vol.22 , pp. 27-55
    • Chou, T.C.1    Talalay, P.2
  • 29
    • 76549129820 scopus 로고    scopus 로고
    • Drug combination studies and their synergy quantification using the Chou–Talalay method
    • COI: 1:CAS:528:DC%2BC3cXltlWksA%3D%3D, PID: 20068163
    • Chou TC (2010) Drug combination studies and their synergy quantification using the Chou–Talalay method. Cancer Res 70:440–446
    • (2010) Cancer Res , vol.70 , pp. 440-446
    • Chou, T.C.1
  • 30
    • 0033957359 scopus 로고    scopus 로고
    • Morphologic and biochemical hallmarks of apoptosis
    • COI: 1:CAS:528:DC%2BD3cXltVGlsg%3D%3D, PID: 10728374
    • Saraste A, Pulkki K (2000) Morphologic and biochemical hallmarks of apoptosis. Cardiovasc Res 45:528–537
    • (2000) Cardiovasc Res , vol.45 , pp. 528-537
    • Saraste, A.1    Pulkki, K.2
  • 31
    • 0029043888 scopus 로고
    • A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V
    • COI: 1:CAS:528:DyaK2MXnt1Ojsbo%3D, PID: 7622868
    • Vermes I, Haanen C, Steffens-Nakken H, Reutelingsperger C (1995) A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V. J Immunol Methods 184:39–51
    • (1995) J Immunol Methods , vol.184 , pp. 39-51
    • Vermes, I.1    Haanen, C.2    Steffens-Nakken, H.3    Reutelingsperger, C.4
  • 32
    • 79551557991 scopus 로고    scopus 로고
    • TGF-beta regulates Nox4, MnSOD and catalase expression, and IL-6 release in airway smooth muscle cells
    • COI: 1:CAS:528:DC%2BC3MXisFyisbg%3D, PID: 21131394
    • Michaeloudes C, Sukkar MB, Khorasani NM, Bhavsar PK, Chung KF (2011) TGF-beta regulates Nox4, MnSOD and catalase expression, and IL-6 release in airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 300:L295–L304
    • (2011) Am J Physiol Lung Cell Mol Physiol , vol.300 , pp. L295-L304
    • Michaeloudes, C.1    Sukkar, M.B.2    Khorasani, N.M.3    Bhavsar, P.K.4    Chung, K.F.5
  • 33
    • 83555174340 scopus 로고    scopus 로고
    • Reactive oxygen species mediated tissue damage in high energy proton irradiated mouse brain
    • COI: 1:CAS:528:DC%2BC3MXhsFCmsbbN, PID: 21948272
    • Baluchamy S, Ravichandran P, Ramesh V et al (2012) Reactive oxygen species mediated tissue damage in high energy proton irradiated mouse brain. Mol Cell Biochem 360:189–195
    • (2012) Mol Cell Biochem , vol.360 , pp. 189-195
    • Baluchamy, S.1    Ravichandran, P.2    Ramesh, V.3
  • 34
    • 79961144637 scopus 로고    scopus 로고
    • Disruption of redox homeostasis and induction of apoptosis by suppression of glutathione synthetase expression in a mammalian cell line
    • COI: 1:CAS:528:DC%2BC3MXpvVWltr0%3D, PID: 21679055
    • Kim SJ, Jung HJ, Lim CJ (2011) Disruption of redox homeostasis and induction of apoptosis by suppression of glutathione synthetase expression in a mammalian cell line. Free Radic Res 45:1040–1051
    • (2011) Free Radic Res , vol.45 , pp. 1040-1051
    • Kim, S.J.1    Jung, H.J.2    Lim, C.J.3
  • 35
    • 33845292901 scopus 로고    scopus 로고
    • Peroxisomes and oxidative stress
    • COI: 1:CAS:528:DC%2BD28XhtlakurbM, PID: 17034877
    • Schrader M, Fahimi HD (2006) Peroxisomes and oxidative stress. Biochim Biophys Acta 1763:1755–1766
    • (2006) Biochim Biophys Acta , vol.1763 , pp. 1755-1766
    • Schrader, M.1    Fahimi, H.D.2
  • 36
    • 84858045324 scopus 로고    scopus 로고
    • Angiotensin II requires zinc and downregulation of the zinc transporters ZnT3 and ZnT10 to induce senescence of vascular smooth muscle cells
    • COI: 1:CAS:528:DC%2BC38XksFGlsbc%3D, PID: 22427991
    • Patrushev N, Seidel-Rogol B, Salazar G (2012) Angiotensin II requires zinc and downregulation of the zinc transporters ZnT3 and ZnT10 to induce senescence of vascular smooth muscle cells. PLoS ONE 7:e33211
    • (2012) PLoS ONE , vol.7
    • Patrushev, N.1    Seidel-Rogol, B.2    Salazar, G.3
  • 37
    • 84927935911 scopus 로고    scopus 로고
    • Heme oxygenase-1: emerging target of cancer therapy
    • PID: 25885228
    • Chau LY (2015) Heme oxygenase-1: emerging target of cancer therapy. J Biomed Sci 22:22
    • (2015) J Biomed Sci , vol.22 , pp. 22
    • Chau, L.Y.1
  • 38
    • 84866536847 scopus 로고    scopus 로고
    • Salinomycin induces autophagy in colon and breast cancer cells with concomitant generation of reactive oxygen species
    • COI: 1:CAS:528:DC%2BC38XhsVaktrbP, PID: 23028492
    • Verdoodt B, Vogt M, Schmitz I, Liffers ST, Tannapfel A, Mirmohammadsadegh A (2012) Salinomycin induces autophagy in colon and breast cancer cells with concomitant generation of reactive oxygen species. PLoS ONE 7:e44132
    • (2012) PLoS ONE , vol.7
    • Verdoodt, B.1    Vogt, M.2    Schmitz, I.3    Liffers, S.T.4    Tannapfel, A.5    Mirmohammadsadegh, A.6
  • 39
    • 33845480548 scopus 로고    scopus 로고
    • Caspase function in programmed cell death
    • COI: 1:CAS:528:DC%2BD28XhtlSqur%2FF, PID: 17082813
    • Kumar S (2007) Caspase function in programmed cell death. Cell Death Differ 14:32–43
    • (2007) Cell Death Differ , vol.14 , pp. 32-43
    • Kumar, S.1
  • 41
    • 84903287499 scopus 로고    scopus 로고
    • Shikonin inhibits the proliferation of human lens epithelial cells by inducing apoptosis through ROS and caspase-dependent pathway
    • PID: 24962386
    • Huang WR, Zhang Y, Tang X (2014) Shikonin inhibits the proliferation of human lens epithelial cells by inducing apoptosis through ROS and caspase-dependent pathway. Molecules 19:7785–7797
    • (2014) Molecules , vol.19 , pp. 7785-7797
    • Huang, W.R.1    Zhang, Y.2    Tang, X.3
  • 42
    • 0033214624 scopus 로고    scopus 로고
    • Cleavage of automodified poly(ADP-ribose) polymerase during apoptosis. Evidence for involvement of caspase-7
    • COI: 1:CAS:528:DyaK1MXmsFWgtbw%3D, PID: 10497198
    • Germain M, Affar EB, D’Amours D, Dixit VM, Salvesen GS, Poirier GG (1999) Cleavage of automodified poly(ADP-ribose) polymerase during apoptosis. Evidence for involvement of caspase-7. J Biol Chem 274:28379–28384
    • (1999) J Biol Chem , vol.274 , pp. 28379-28384
    • Germain, M.1    Affar, E.B.2    D’Amours, D.3    Dixit, V.M.4    Salvesen, G.S.5    Poirier, G.G.6
  • 43
    • 80054993459 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases and reactive oxygen species: how can ROS activate MAPK pathways?
    • PID: 21637379
    • Son Y, Cheong YK, Kim NH, Chung HT, Kang DG, Pae HO (2011) Mitogen-activated protein kinases and reactive oxygen species: how can ROS activate MAPK pathways? J Signal Transduct 2011:792639
    • (2011) J Signal Transduct , vol.2011 , pp. 792639
    • Son, Y.1    Cheong, Y.K.2    Kim, N.H.3    Chung, H.T.4    Kang, D.G.5    Pae, H.O.6


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