Flux balance analysis predicts Warburg-like effects of mouse hepatocyte deficient in miR-122a

PLoS Computational Biology

Volumn 13, Issue 7, 2017, Pages

  Wu, Hua Qing ^a   Cheng, Mei Ling ^b,c   Lai, Jin Mei ^d   Wu, Hsuan Hui ^e   Chen, Meng Chun ^a   Liu, Wen Huan ^a   Wu, Wu Hsiung ^a   Chang, Peter Mu Hsin ^e,f   Huang, Chi Ying F ^e,g   Tsou, Ann Ping ^e   Shiao, Ming Shi ^b   Wang, Feng Sheng ^a  

^a NATIONAL CHUNG CHENG UNIVERSITY   (Taiwan)

^b CHANG GUNG UNIVERSITY   (Taiwan)

^c CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^d FU JEN CATHOLIC UNIVERSITY   (Taiwan)

^e NATIONAL YANG MING UNIVERSITY   (Taiwan)

^f TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^g KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER CELLS; GENE EXPRESSION; MAMMALS; METABOLISM; RNA;

FLUX BALANCE ANALYSIS; GENOME-SCALE METABOLIC MODELING; HEPATOCYTES; HUMAN BODIES; KNOCKOUT MICE; LIVER METABOLISMS; METABOLIC FUNCTION; MICE HEPATOCYTES; MICE LIVER; SIMILARITY RATIO;

LIQUID CHROMATOGRAPHY;

2 CYANO N (2,5 DIBROMOPHENYL) 3 HYDROXYCROTONAMIDE; MICRORNA; MICRORNA 122A; UNCLASSIFIED DRUG; WITHAFERIN A; GLUCOSE; MIRN122 MICRORNA, MOUSE;

AEROBIC GLYCOLYSIS; ANALYTIC METHOD; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DDC GENE; DOWN REGULATION; EXTRACELLULAR MATRIX; FLUX BALANCE ANALYSIS; GENE; GENE DELETION; GENE EXPRESSION; GENE TARGETING; GLUCOSE METABOLISM; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; LIVER CELL; MATHEMATICAL COMPUTING; MATHEMATICAL MODEL; METABOLOMICS; MIR122A GENE; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; UPREGULATION; ANIMAL; GENETICS; HUMAN; KNOCKOUT MOUSE; LIVER; LIVER TUMOR; METABOLIC FLUX ANALYSIS; METABOLISM; PROCEDURES;

ANIMALS; GLUCOSE; HEPATOCYTES; HUMANS; LIVER; LIVER NEOPLASMS; METABOLIC FLUX ANALYSIS; METABOLOMICS; MICE; MICE, KNOCKOUT; MICRORNAS;

EID: 85026625357     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1005618     Document Type: Article

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