메뉴 건너뛰기




Volumn 69, Issue 12, 2009, Pages 4941-4944

Bispecific T-cell engaging antibodies for cancer therapy

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BISPECIFIC ANTIBODY; BISPECIFIC T CELL ENGAGER ANTIBODY; BLINATUMOMAB; CANCER VACCINE; CARCINOEMBRYONIC ANTIGEN; CD19 ANTIGEN; CD20 ANTIBODY; CD3 ANTIGEN; CD33 ANTIGEN; EPHRIN RECEPTOR A2; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPITHELIAL CELL ADHESION MOLECULE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN G1 ANTIBODY; INTERLEUKIN 2; MT 103; MT 110; T LYMPHOCYTE RECEPTOR; TOLL LIKE RECEPTOR AGONIST; UNCLASSIFIED DRUG;

EID: 67449156132     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-09-0547     Document Type: Review
Times cited : (485)

References (22)
  • 1
    • 0021832361 scopus 로고
    • Hybrid antibodies can target sites for attack by T cells
    • DOI 10.1038/314628a0
    • Staerz UD, Kanagawa O, Bevan MJ. Hybrid antibodies can target sites for attack by T cells. Nature 1985;314:628-631 (Pubitemid 15080840)
    • (1985) Nature , vol.314 , Issue.6012 , pp. 628-631
    • Staerz, U.D.1    Kanagawa, O.2    Bevan, M.J.3
  • 2
    • 0035524114 scopus 로고    scopus 로고
    • Improving the efficacy of antibody-based cancer therapies
    • Carter P. Improving the efficacy of antibody-based cancer therapies. Nat Rev Cancer 2001;1:118-129 (Pubitemid 33741887)
    • (2001) Nature Reviews Cancer , vol.1 , Issue.2 , pp. 118-129
    • Carter, P.1
  • 3
  • 4
    • 0030727901 scopus 로고    scopus 로고
    • Clinical experience with CD64-directed immunotherapy. An overview
    • DOI 10.1007/s002620050435
    • Curnow RT. Clinical experience with CD64-directed immunotherapy. An overview. Cancer Immunol Immunother 1997;45:210-215 (Pubitemid 27521462)
    • (1997) Cancer Immunology Immunotherapy , vol.45 , Issue.3-4 , pp. 210-215
    • Curnow, R.T.1
  • 5
    • 0026089987 scopus 로고
    • Single chain antibody variable regions
    • Bird RE, Walker BW. Single chain antibody variable regions. Trends Biotechnol 1991;9:132-137 (Pubitemid 121003095)
    • (1991) Trends in Biotechnology , vol.9 , Issue.1 , pp. 132-137
    • Bird, R.E.1    Walker, B.W.2
  • 6
    • 0029148633 scopus 로고
    • A small bispecific antibody construct expressed as a functional single-chain molecule with high tumor cell cytotoxicity
    • Mack M, Riethmuller G, Kufer P. A small bispecific antibody construct expressed as a functional single-chain molecule with high tumor cell cytotoxicity. Proc Natl Acad Sci U S A 1995;92:7021-7025
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 7021-7025
    • Mack, M.1    Riethmuller, G.2    Kufer, P.3
  • 9
    • 41549119824 scopus 로고    scopus 로고
    • BiTE: A new class of antibodies that recruit T cells
    • Baeuerle PA, Reinhardt C, Kufer P. BiTE: A new class of antibodies that recruit T cells. Drugs Future 2008;33:137-147
    • (2008) Drugs Future , vol.33 , pp. 137-147
    • Baeuerle, P.A.1    Reinhardt, C.2    Kufer, P.3
  • 10
    • 58849085569 scopus 로고    scopus 로고
    • BiTE: Teaching antibodies to engage T cells for cancer therapy
    • Baeuerle PA, Kufer P, Bargou R. BiTE: Teaching antibodies to engage T cells for cancer therapy. Curr Opin Mol Ther 2009;11:22-30.
    • (2009) Curr Opin Mol Ther , vol.11 , pp. 22-30
    • Baeuerle, P.A.1    Kufer, P.2    Bargou, R.3
  • 11
    • 49649120397 scopus 로고    scopus 로고
    • Tumor regression in cancer patients by very low doses of a T cell-engaging antibody
    • Bargou R, Leo E, Zugmaier G, et al. Tumor regression in cancer patients by very low doses of a T cell-engaging antibody. Science 2008;321:974-977
    • (2008) Science , vol.321 , pp. 974-977
    • Bargou, R.1    Leo, E.2    Zugmaier, G.3
  • 12
    • 67449119748 scopus 로고    scopus 로고
    • Treatment with anti-CD19 BiTE antibody blinatumomab (MT103/MEDI-538) is able to eliminate minimal residual disease (MRD) in patients with B-precursor acute lmphoblastic leukemia (ALL): First results of ongoing phase 2 study
    • ASH Annual Meeting Abstract
    • Topp M, Goekbuget N, Kufer P, et al. Treatment with anti-CD19 BiTE antibody blinatumomab (MT103/MEDI-538) is able to eliminate minimal residual disease (MRD) in patients with B-precursor acute lmphoblastic leukemia (ALL): First results of ongoing phase 2 study [ASH Annual Meeting Abstract]. Blood 2008;112:1926.
    • (2008) Blood , vol.112 , pp. 1926
    • Topp, M.1    Goekbuget, N.2    Kufer, P.3
  • 14
    • 59749103834 scopus 로고    scopus 로고
    • Nuclear signalling by tumour-associated antigen EpCAM
    • Published Online Jan 11
    • Maetzel D, Denzel S, Mack B, et al: Nuclear signalling by tumour-associated antigen EpCAM. Nat Cell Biol. Published Online 2009 Jan 11.
    • (2009) Nat Cell Biol.
    • Maetzel, D.1    Denzel, S.2    Mack, B.3
  • 16
    • 33846860644 scopus 로고    scopus 로고
    • CD8+ T-cell content in diagnostic lymph nodes measured by flow cytometry is a predictor of survival in follicular lymphoma
    • DOI 10.1158/1078-0432.CCR-06-1734
    • Wahlin BE, Sander B, Christensson B, Kimby E. CD8+ T-cell content in diagnostic lymph nodes measured by flow cytometry is a predictor of survival in follicular lymphoma. Clin Cancer Res 2007;13:388-397 (Pubitemid 46225341)
    • (2007) Clinical Cancer Research , vol.13 , Issue.2 I , pp. 388-397
    • Wahlin, B.E.1    Sander, B.2    Christensson, B.3    Kimby, E.4
  • 17
    • 33947259319 scopus 로고    scopus 로고
    • Immunosuppressive strategies that are mediated by tumor cells
    • DOI 10.1146/annurev.immunol.25.022106.141609
    • Rabinovich GA, Gabrilovich D, Sotomayor EM. Immunosuppressive strategies that are mediated by tumor cells. Annu Rev Immunol 2007;25:267-296 (Pubitemid 46697910)
    • (2007) Annual Review of Immunology , vol.25 , pp. 267-296
    • Rabinovich, G.A.1    Gabrilovich, D.2    Sotomayor, E.M.3
  • 18
    • 51649124283 scopus 로고    scopus 로고
    • Targeted therapies to improve tumor immunotherapy
    • Begley J, Ribas A. Targeted therapies to improve tumor immunotherapy. Clin Cancer Res 2008;14:4385-4391
    • (2008) Clin Cancer Res , vol.14 , pp. 4385-4391
    • Begley, J.1    Ribas, A.2
  • 21
    • 64649103924 scopus 로고    scopus 로고
    • Mode of cytotoxic action of T cell-engaging BiTE antibody MT110
    • Haas C, Krinner E, Brischwein K, et al. Mode of cytotoxic action of T cell-engaging BiTE antibody MT110. Immunobiology 2009;214:441-453
    • (2009) Immunobiology , vol.214 , pp. 441-453
    • Haas, C.1    Krinner, E.2    Brischwein, K.3
  • 22
    • 33847137354 scopus 로고    scopus 로고
    • In vivo imaging of cytotoxic T cell infiltration and elimination of a solid tumor
    • Boissonnas A, Fether L, Zeelenberg IS, Hugues S, Amigorena S. In vivo imaging of cytotoxic T cell infiltration and elimination of a solid tumor. J Exp Med 2007;204:345-356
    • (2007) J Exp Med , vol.204 , pp. 345-356
    • Boissonnas, A.1    Fether, L.2    Zeelenberg, I.S.3    Hugues, S.4    Amigorena, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.