-
1
-
-
0021832361
-
Hybrid antibodies can target sites for attack by T cells
-
DOI 10.1038/314628a0
-
Staerz UD, Kanagawa O, Bevan MJ. Hybrid antibodies can target sites for attack by T cells. Nature 1985;314:628-631 (Pubitemid 15080840)
-
(1985)
Nature
, vol.314
, Issue.6012
, pp. 628-631
-
-
Staerz, U.D.1
Kanagawa, O.2
Bevan, M.J.3
-
2
-
-
0035524114
-
Improving the efficacy of antibody-based cancer therapies
-
Carter P. Improving the efficacy of antibody-based cancer therapies. Nat Rev Cancer 2001;1:118-129 (Pubitemid 33741887)
-
(2001)
Nature Reviews Cancer
, vol.1
, Issue.2
, pp. 118-129
-
-
Carter, P.1
-
4
-
-
0030727901
-
Clinical experience with CD64-directed immunotherapy. An overview
-
DOI 10.1007/s002620050435
-
Curnow RT. Clinical experience with CD64-directed immunotherapy. An overview. Cancer Immunol Immunother 1997;45:210-215 (Pubitemid 27521462)
-
(1997)
Cancer Immunology Immunotherapy
, vol.45
, Issue.3-4
, pp. 210-215
-
-
Curnow, R.T.1
-
5
-
-
0026089987
-
Single chain antibody variable regions
-
Bird RE, Walker BW. Single chain antibody variable regions. Trends Biotechnol 1991;9:132-137 (Pubitemid 121003095)
-
(1991)
Trends in Biotechnology
, vol.9
, Issue.1
, pp. 132-137
-
-
Bird, R.E.1
Walker, B.W.2
-
6
-
-
0029148633
-
A small bispecific antibody construct expressed as a functional single-chain molecule with high tumor cell cytotoxicity
-
Mack M, Riethmuller G, Kufer P. A small bispecific antibody construct expressed as a functional single-chain molecule with high tumor cell cytotoxicity. Proc Natl Acad Sci U S A 1995;92:7021-7025
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 7021-7025
-
-
Mack, M.1
Riethmuller, G.2
Kufer, P.3
-
7
-
-
0037143806
-
Extremely potent, rapid and costimulation-independent cytotoxic T-cell response against lymphoma cells catalyzed by a single-chain bispecific antibody
-
DOI 10.1002/ijc.10557
-
Dreier T, Lorenczewski G, Brandl C, et al. Extremely potent, rapid and costimulation-independent cytotoxic T-cell response against lymphoma cells catalyzed by a single-chain bispecific antibody. Int J Cancer 2002;100:690-697 (Pubitemid 34832980)
-
(2002)
International Journal of Cancer
, vol.100
, Issue.6
, pp. 690-697
-
-
Dreier, T.1
Lorenczewski, G.2
Brandl, C.3
Hoffmann, P.4
Syring, U.5
Hanakam, F.6
Kufer, P.7
Riethmuller, G.8
Bargou, R.9
Baeuerle, P.A.10
-
8
-
-
37349123501
-
Strictly target cell-dependent activation of T cells by bispecific single-chain antibody constructs of the BiTE class
-
DOI 10.1097/CJI.0b013e318156750c, PII 0000237120071100000002
-
Brischwein K, Parr L, Pflanz S, et al. Strictly target cell-dependent activation of T cells by bispecific single-chain antibody constructs of the BiTE class. J Immunother 2007;30:798-807. (Pubitemid 350295358)
-
(2007)
Journal of Immunotherapy
, vol.30
, Issue.8
, pp. 798-807
-
-
Brischwein, K.1
Parr, L.2
Pflanz, S.3
Volkland, J.4
Lumsden, J.5
Klinger, M.6
Locher, M.7
Hammond, S.A.8
Kiener, P.9
Kufer, P.10
Schlereth, B.11
Baeuerle, P.A.12
-
9
-
-
41549119824
-
BiTE: A new class of antibodies that recruit T cells
-
Baeuerle PA, Reinhardt C, Kufer P. BiTE: A new class of antibodies that recruit T cells. Drugs Future 2008;33:137-147
-
(2008)
Drugs Future
, vol.33
, pp. 137-147
-
-
Baeuerle, P.A.1
Reinhardt, C.2
Kufer, P.3
-
10
-
-
58849085569
-
BiTE: Teaching antibodies to engage T cells for cancer therapy
-
Baeuerle PA, Kufer P, Bargou R. BiTE: Teaching antibodies to engage T cells for cancer therapy. Curr Opin Mol Ther 2009;11:22-30.
-
(2009)
Curr Opin Mol Ther
, vol.11
, pp. 22-30
-
-
Baeuerle, P.A.1
Kufer, P.2
Bargou, R.3
-
11
-
-
49649120397
-
Tumor regression in cancer patients by very low doses of a T cell-engaging antibody
-
Bargou R, Leo E, Zugmaier G, et al. Tumor regression in cancer patients by very low doses of a T cell-engaging antibody. Science 2008;321:974-977
-
(2008)
Science
, vol.321
, pp. 974-977
-
-
Bargou, R.1
Leo, E.2
Zugmaier, G.3
-
12
-
-
67449119748
-
Treatment with anti-CD19 BiTE antibody blinatumomab (MT103/MEDI-538) is able to eliminate minimal residual disease (MRD) in patients with B-precursor acute lmphoblastic leukemia (ALL): First results of ongoing phase 2 study
-
ASH Annual Meeting Abstract
-
Topp M, Goekbuget N, Kufer P, et al. Treatment with anti-CD19 BiTE antibody blinatumomab (MT103/MEDI-538) is able to eliminate minimal residual disease (MRD) in patients with B-precursor acute lmphoblastic leukemia (ALL): First results of ongoing phase 2 study [ASH Annual Meeting Abstract]. Blood 2008;112:1926.
-
(2008)
Blood
, vol.112
, pp. 1926
-
-
Topp, M.1
Goekbuget, N.2
Kufer, P.3
-
13
-
-
28744445538
-
MT110: A novel bispecific single-chain antibody construct with high efficacy in eradicating established tumors
-
DOI 10.1016/j.molimm.2005.07.034, PII S0161589005002956
-
Brischwein K, Schlereth B, Guller B, et al. MT110: a novel bispecific single-chain antibody construct with high efficacy in eradicating established tumors. Mol Immunol 2006;43:1129-1143 (Pubitemid 43063166)
-
(2006)
Molecular Immunology
, vol.43
, Issue.8
, pp. 1129-1143
-
-
Brischwein, K.1
Schlereth, B.2
Guller, B.3
Steiger, C.4
Wolf, A.5
Lutterbuese, R.6
Offner, S.7
Locher, M.8
Urbig, T.9
Raum, T.10
Kleindienst, P.11
Wimberger, P.12
Kimmig, R.13
Fichtner, I.14
Kufer, P.15
Hofmeister, R.16
Da Silva, A.J.17
Baeuerle, P.A.18
-
14
-
-
59749103834
-
Nuclear signalling by tumour-associated antigen EpCAM
-
Published Online Jan 11
-
Maetzel D, Denzel S, Mack B, et al: Nuclear signalling by tumour-associated antigen EpCAM. Nat Cell Biol. Published Online 2009 Jan 11.
-
(2009)
Nat Cell Biol.
-
-
Maetzel, D.1
Denzel, S.2
Mack, B.3
-
15
-
-
33749319703
-
Type, density, and location of immune cells within human colorectal tumors predict clinical outcome
-
DOI 10.1126/science.1129139
-
Galon J, Costes A, Sanchez-Cabo F, et al. Type, density, and location of immune cells within human colorectal tumors predicts clinical outcome. Science 2006;313:1960-1964 (Pubitemid 44498003)
-
(2006)
Science
, vol.313
, Issue.5795
, pp. 1960-1964
-
-
Galon, J.1
Costes, A.2
Sanchez-Cabo, F.3
Kirilovsky, A.4
Mlecnik, B.5
Lagorce-Pages, C.6
Tosolini, M.7
Camus, M.8
Berger, A.9
Wind, P.10
Zinzindohoue, F.11
Bruneval, P.12
Cugnenc, P.-H.13
Trajanoski, Z.14
Fridman, W.-H.15
Pages, F.16
-
16
-
-
33846860644
-
CD8+ T-cell content in diagnostic lymph nodes measured by flow cytometry is a predictor of survival in follicular lymphoma
-
DOI 10.1158/1078-0432.CCR-06-1734
-
Wahlin BE, Sander B, Christensson B, Kimby E. CD8+ T-cell content in diagnostic lymph nodes measured by flow cytometry is a predictor of survival in follicular lymphoma. Clin Cancer Res 2007;13:388-397 (Pubitemid 46225341)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.2 I
, pp. 388-397
-
-
Wahlin, B.E.1
Sander, B.2
Christensson, B.3
Kimby, E.4
-
17
-
-
33947259319
-
Immunosuppressive strategies that are mediated by tumor cells
-
DOI 10.1146/annurev.immunol.25.022106.141609
-
Rabinovich GA, Gabrilovich D, Sotomayor EM. Immunosuppressive strategies that are mediated by tumor cells. Annu Rev Immunol 2007;25:267-296 (Pubitemid 46697910)
-
(2007)
Annual Review of Immunology
, vol.25
, pp. 267-296
-
-
Rabinovich, G.A.1
Gabrilovich, D.2
Sotomayor, E.M.3
-
18
-
-
51649124283
-
Targeted therapies to improve tumor immunotherapy
-
Begley J, Ribas A. Targeted therapies to improve tumor immunotherapy. Clin Cancer Res 2008;14:4385-4391
-
(2008)
Clin Cancer Res
, vol.14
, pp. 4385-4391
-
-
Begley, J.1
Ribas, A.2
-
20
-
-
4344644908
-
High frequeacy of functionally active Melan-A-specific T cells in a patient with progressive immunoproteasome-deficient melanoma
-
DOI 10.1158/0008-5472.CAN-04-1341
-
Meidenbauer N, Zippelius A, Pittet MJ, et al. High frequency of functionally active Melan-A-specific T cells in a patient with progressive immunoproteasome-deficient melanoma. Cancer Res 2004;64:6319-6326 (Pubitemid 39129437)
-
(2004)
Cancer Research
, vol.64
, Issue.17
, pp. 6319-6326
-
-
Meidenbauer, N.1
Zippelius, A.2
Pittet, M.J.3
Laumer, M.4
Vogl, S.5
Heymann, J.6
Rehli, M.7
Seliger, B.8
Schwarz, S.9
Le Gal, F.-A.10
Dietrich, P.Y.11
Andreesen, R.12
Romero, P.13
Mackensen, A.14
-
21
-
-
64649103924
-
Mode of cytotoxic action of T cell-engaging BiTE antibody MT110
-
Haas C, Krinner E, Brischwein K, et al. Mode of cytotoxic action of T cell-engaging BiTE antibody MT110. Immunobiology 2009;214:441-453
-
(2009)
Immunobiology
, vol.214
, pp. 441-453
-
-
Haas, C.1
Krinner, E.2
Brischwein, K.3
-
22
-
-
33847137354
-
In vivo imaging of cytotoxic T cell infiltration and elimination of a solid tumor
-
Boissonnas A, Fether L, Zeelenberg IS, Hugues S, Amigorena S. In vivo imaging of cytotoxic T cell infiltration and elimination of a solid tumor. J Exp Med 2007;204:345-356
-
(2007)
J Exp Med
, vol.204
, pp. 345-356
-
-
Boissonnas, A.1
Fether, L.2
Zeelenberg, I.S.3
Hugues, S.4
Amigorena, S.5
|