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Volumn 491, Issue 3, 2017, Pages 636-641

Quercetin ameliorates learning and memory via the Nrf2-ARE signaling pathway in D-galactose-induced neurotoxicity in mice

Author keywords

Apoptosis; D galactose; Morris water maze; Mouse brain aging; Nrf2 ARE; Quercetin

Indexed keywords

BRUSATOL; GALACTOSE; HEME OXYGENASE 1; QUERCETIN; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR NRF2; ANTIOXIDANT; ARYLESTERASE; CARBOXYLESTERASE; NEUROPROTECTIVE AGENT; NEUROTOXIN; NFE2L2 PROTEIN, MOUSE;

EID: 85026373413     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2017.07.151     Document Type: Article
Times cited : (92)

References (40)
  • 1
  • 2
    • 52649085345 scopus 로고    scopus 로고
    • Working memory capacity for spoken sentences decreases with adult ageing: recall of fewer but not smaller chunks in older adults
    • Gilchrist, A.L., Cowan, N., Naveh-Benjamin, M., Working memory capacity for spoken sentences decreases with adult ageing: recall of fewer but not smaller chunks in older adults. Memory 16 (2008), 773–787.
    • (2008) Memory , vol.16 , pp. 773-787
    • Gilchrist, A.L.1    Cowan, N.2    Naveh-Benjamin, M.3
  • 3
    • 54049086526 scopus 로고    scopus 로고
    • Recognition memory measures yield disproportionate effects of aging on learning face-name associations
    • James, L.E., Fogler, K.A., Tauber, S.K., Recognition memory measures yield disproportionate effects of aging on learning face-name associations. Psychol. aging 23 (2008), 657–664.
    • (2008) Psychol. aging , vol.23 , pp. 657-664
    • James, L.E.1    Fogler, K.A.2    Tauber, S.K.3
  • 4
    • 14844285338 scopus 로고    scopus 로고
    • Modulation of age-associated oxidative DNA damage in rat brain cerebral cortex, striatum and hippocampus by L-carnitine
    • Haripriya, D., Sangeetha, P., Kanchana, A., Balu, M., Panneerselvam, C., Modulation of age-associated oxidative DNA damage in rat brain cerebral cortex, striatum and hippocampus by L-carnitine. Exp. Gerontol. 40 (2005), 129–135.
    • (2005) Exp. Gerontol. , vol.40 , pp. 129-135
    • Haripriya, D.1    Sangeetha, P.2    Kanchana, A.3    Balu, M.4    Panneerselvam, C.5
  • 5
    • 77049308856 scopus 로고
    • Aging: a theory based on free radical and radiation chemistry
    • Harman, D., Aging: a theory based on free radical and radiation chemistry. J. Gerontol. 11 (1956), 298–300.
    • (1956) J. Gerontol. , vol.11 , pp. 298-300
    • Harman, D.1
  • 7
    • 11444259804 scopus 로고    scopus 로고
    • Behavioural study of the D-galactose induced aging model in C57BL/6J mice
    • Wei, H., Li, L., Song, Q., Ai, H., Chu, J., Li, W., Behavioural study of the D-galactose induced aging model in C57BL/6J mice. Behav. Brain Res. 157 (2005), 245–251.
    • (2005) Behav. Brain Res. , vol.157 , pp. 245-251
    • Wei, H.1    Li, L.2    Song, Q.3    Ai, H.4    Chu, J.5    Li, W.6
  • 8
    • 84919882738 scopus 로고    scopus 로고
    • Ligustilide prevents cognitive impairment and attenuates neurotoxicity in D-galactose induced aging mice brain
    • Li, J.J., Zhu, Q., Lu, Y.P., Zhao, P., Feng, Z.B., Qian, Z.M., Zhu, L., Ligustilide prevents cognitive impairment and attenuates neurotoxicity in D-galactose induced aging mice brain. Brain Res. 1595 (2015), 19–28.
    • (2015) Brain Res. , vol.1595 , pp. 19-28
    • Li, J.J.1    Zhu, Q.2    Lu, Y.P.3    Zhao, P.4    Feng, Z.B.5    Qian, Z.M.6    Zhu, L.7
  • 9
    • 59949093248 scopus 로고    scopus 로고
    • Neuroprotective effects of (-)-epigallocatechin-3-gallate on aging mice induced by D-galactose
    • He, M., Zhao, L., Wei, M.J., Yao, W.F., Zhao, H.S., Chen, F.J., Neuroprotective effects of (-)-epigallocatechin-3-gallate on aging mice induced by D-galactose. Biol. Pharm. Bull. 32 (2009), 55–60.
    • (2009) Biol. Pharm. Bull. , vol.32 , pp. 55-60
    • He, M.1    Zhao, L.2    Wei, M.J.3    Yao, W.F.4    Zhao, H.S.5    Chen, F.J.6
  • 10
    • 0032969493 scopus 로고    scopus 로고
    • Advanced glycation in D-galactose induced mouse aging model
    • Song, X., Bao, M., Li, D., Li, Y.M., Advanced glycation in D-galactose induced mouse aging model. Mech. ageing Dev. 108 (1999), 239–251.
    • (1999) Mech. ageing Dev. , vol.108 , pp. 239-251
    • Song, X.1    Bao, M.2    Li, D.3    Li, Y.M.4
  • 11
    • 0027055332 scopus 로고
    • Age-associated oxygen damage and mutations in mitochondrial DNA in human hearts
    • Hayakawa, M., Hattori, K., Sugiyama, S., Ozawa, T., Age-associated oxygen damage and mutations in mitochondrial DNA in human hearts. Biochem. biophys. Res. Commun. 189 (1992), 979–985.
    • (1992) Biochem. biophys. Res. Commun. , vol.189 , pp. 979-985
    • Hayakawa, M.1    Hattori, K.2    Sugiyama, S.3    Ozawa, T.4
  • 12
    • 33644649421 scopus 로고    scopus 로고
    • Nrf2: a potential molecular target for cancer chemoprevention by natural compounds
    • Jeong, W.S., Jun, M., Kong, A.N., Nrf2: a potential molecular target for cancer chemoprevention by natural compounds. Antioxid. redox Signal. 8 (2006), 99–106.
    • (2006) Antioxid. redox Signal. , vol.8 , pp. 99-106
    • Jeong, W.S.1    Jun, M.2    Kong, A.N.3
  • 13
    • 0035853157 scopus 로고    scopus 로고
    • Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice
    • Ramos-Gomez, M., Kwak, M.K., Dolan, P.M., Itoh, K., Yamamoto, M., Talalay, P., Kensler, T.W., Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice. Proc. Natl. Acad. Sci. U. S. A. 98 (2001), 3410–3415.
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , pp. 3410-3415
    • Ramos-Gomez, M.1    Kwak, M.K.2    Dolan, P.M.3    Itoh, K.4    Yamamoto, M.5    Talalay, P.6    Kensler, T.W.7
  • 14
    • 84857060182 scopus 로고    scopus 로고
    • Age-related changes of Nrf2 and phosphorylated GSK-3beta in a mouse model of accelerated aging (SAMP8)
    • Tomobe, K., Shinozuka, T., Kuroiwa, M., Nomura, Y., Age-related changes of Nrf2 and phosphorylated GSK-3beta in a mouse model of accelerated aging (SAMP8). Archives Gerontol. Geriatr. 54 (2012), e1–7.
    • (2012) Archives Gerontol. Geriatr. , vol.54 , pp. e1-7
    • Tomobe, K.1    Shinozuka, T.2    Kuroiwa, M.3    Nomura, Y.4
  • 15
    • 84880148379 scopus 로고    scopus 로고
    • Chronic testosterone propionate supplement could activated the Nrf2-ARE pathway in the brain and ameliorated the behaviors of aged rats
    • Zhang, G.L., Wang, W., Kang, Y.X., Xue, Y., Yang, H., Zhou, C.M., Shi, G.M., Chronic testosterone propionate supplement could activated the Nrf2-ARE pathway in the brain and ameliorated the behaviors of aged rats. Behav. Brain Res. 252 (2013), 388–395.
    • (2013) Behav. Brain Res. , vol.252 , pp. 388-395
    • Zhang, G.L.1    Wang, W.2    Kang, Y.X.3    Xue, Y.4    Yang, H.5    Zhou, C.M.6    Shi, G.M.7
  • 16
    • 84861464050 scopus 로고    scopus 로고
    • Crosstalk between Nrf2 and the proteasome: therapeutic potential of Nrf2 inducers in vascular disease and aging
    • Chapple, S.J., Siow, R.C.M., Mann, G.E., Crosstalk between Nrf2 and the proteasome: therapeutic potential of Nrf2 inducers in vascular disease and aging. Int. J. Biochem. Cell B 44 (2012), 1315–1320.
    • (2012) Int. J. Biochem. Cell B , vol.44 , pp. 1315-1320
    • Chapple, S.J.1    Siow, R.C.M.2    Mann, G.E.3
  • 17
    • 84862823149 scopus 로고    scopus 로고
    • Allicin ameliorates cognitive deficits ageing-induced learning and memory deficits through enhancing of Nrf2 antioxidant signaling pathways
    • Li, X.H., Li, C.Y., Lu, J.M., Tian, R.B., Wei, J., Allicin ameliorates cognitive deficits ageing-induced learning and memory deficits through enhancing of Nrf2 antioxidant signaling pathways. Neurosci. Lett. 514 (2012), 46–50.
    • (2012) Neurosci. Lett. , vol.514 , pp. 46-50
    • Li, X.H.1    Li, C.Y.2    Lu, J.M.3    Tian, R.B.4    Wei, J.5
  • 18
    • 84994008595 scopus 로고    scopus 로고
    • Sulforaphane activates the cerebral vascular Nrf2-ARE pathway and suppresses inflammation to attenuate cerebral vasospasm in rat with subarachnoid hemorrhage
    • Zhao, X., Wen, L., Dong, M., Lu, X., Sulforaphane activates the cerebral vascular Nrf2-ARE pathway and suppresses inflammation to attenuate cerebral vasospasm in rat with subarachnoid hemorrhage. Brain Res. 1653 (2016), 1–7.
    • (2016) Brain Res. , vol.1653 , pp. 1-7
    • Zhao, X.1    Wen, L.2    Dong, M.3    Lu, X.4
  • 19
    • 56349157854 scopus 로고    scopus 로고
    • Benefits from dietary polyphenols for brain aging and Alzheimer's disease
    • Rossi, L., Mazzitelli, S., Arciello, M., Capo, C.R., Rotilio, G., Benefits from dietary polyphenols for brain aging and Alzheimer's disease. Neurochem. Res. 33 (2008), 2390–2400.
    • (2008) Neurochem. Res. , vol.33 , pp. 2390-2400
    • Rossi, L.1    Mazzitelli, S.2    Arciello, M.3    Capo, C.R.4    Rotilio, G.5
  • 22
    • 84979679258 scopus 로고    scopus 로고
    • Quercetin ameliorates ischemia/reperfusion-induced cognitive deficits by inhibiting ASK1/JNK3/caspase-3 by enhancing the Akt signaling pathway
    • Pei, B., Yang, M., Qi, X., Shen, X., Chen, X., Zhang, F., Quercetin ameliorates ischemia/reperfusion-induced cognitive deficits by inhibiting ASK1/JNK3/caspase-3 by enhancing the Akt signaling pathway. Biochem. biophys. Res. Commun. 478 (2016), 199–205.
    • (2016) Biochem. biophys. Res. Commun. , vol.478 , pp. 199-205
    • Pei, B.1    Yang, M.2    Qi, X.3    Shen, X.4    Chen, X.5    Zhang, F.6
  • 23
    • 84901481027 scopus 로고    scopus 로고
    • Chronic administration of quercetin prevent spatial learning and memory deficits provoked by chronic stress in rats
    • Mohammadi, H.S., Goudarzi, I., Lashkarbolouki, T., Abrari, K., Elahdadi Salmani, M., Chronic administration of quercetin prevent spatial learning and memory deficits provoked by chronic stress in rats. Behav. Brain Res. 270 (2014), 196–205.
    • (2014) Behav. Brain Res. , vol.270 , pp. 196-205
    • Mohammadi, H.S.1    Goudarzi, I.2    Lashkarbolouki, T.3    Abrari, K.4    Elahdadi Salmani, M.5
  • 24
    • 79952986535 scopus 로고    scopus 로고
    • The role of ASIC1a in neuroprotection elicited by quercetin in focal cerebral ischemia
    • Pandey, A.K., Hazari, P.P., Patnaik, R., Mishra, A.K., The role of ASIC1a in neuroprotection elicited by quercetin in focal cerebral ischemia. Brain Res. 1383 (2011), 289–299.
    • (2011) Brain Res. , vol.1383 , pp. 289-299
    • Pandey, A.K.1    Hazari, P.P.2    Patnaik, R.3    Mishra, A.K.4
  • 25
    • 77249130189 scopus 로고    scopus 로고
    • Protective effect of quercetin against intracerebral streptozotocin induced reduction in cerebral blood flow and impairment of memory in mice
    • Tota, S., Awasthi, H., Kamat, P.K., Nath, C., Hanif, K., Protective effect of quercetin against intracerebral streptozotocin induced reduction in cerebral blood flow and impairment of memory in mice. Behav. Brain Res. 209 (2010), 73–79.
    • (2010) Behav. Brain Res. , vol.209 , pp. 73-79
    • Tota, S.1    Awasthi, H.2    Kamat, P.K.3    Nath, C.4    Hanif, K.5
  • 26
    • 84871432763 scopus 로고    scopus 로고
    • Quercetin attenuates cell apoptosis in focal cerebral ischemia rat brain via activation of BDNF-TrkB-PI3K/Akt signaling pathway
    • Yao, R.Q., Qi, D.S., Yu, H.L., Liu, J., Yang, L.H., Wu, X.X., Quercetin attenuates cell apoptosis in focal cerebral ischemia rat brain via activation of BDNF-TrkB-PI3K/Akt signaling pathway. Neurochem. Res. 37 (2012), 2777–2786.
    • (2012) Neurochem. Res. , vol.37 , pp. 2777-2786
    • Yao, R.Q.1    Qi, D.S.2    Yu, H.L.3    Liu, J.4    Yang, L.H.5    Wu, X.X.6
  • 27
    • 84896739800 scopus 로고    scopus 로고
    • Quercetin improves hypoxia-ischemia induced cognitive deficits via promoting remyelination in neonatal rat
    • Qu, X.B., Qi, D.S., Dong, F.X., Wang, B., Guo, R., Luo, M.J., Yao, R.Q., Quercetin improves hypoxia-ischemia induced cognitive deficits via promoting remyelination in neonatal rat. Brain Res. 1553 (2014), 31–40.
    • (2014) Brain Res. , vol.1553 , pp. 31-40
    • Qu, X.B.1    Qi, D.S.2    Dong, F.X.3    Wang, B.4    Guo, R.5    Luo, M.J.6    Yao, R.Q.7
  • 28
    • 33745377482 scopus 로고    scopus 로고
    • Quercetin reverses D-galactose induced neurotoxicity in mouse brain
    • Lu, J., Zheng, Y.L., Luo, L., Wu, D.M., Sun, D.X., Feng, Y.J., Quercetin reverses D-galactose induced neurotoxicity in mouse brain. Behav. Brain Res. 171 (2006), 251–260.
    • (2006) Behav. Brain Res. , vol.171 , pp. 251-260
    • Lu, J.1    Zheng, Y.L.2    Luo, L.3    Wu, D.M.4    Sun, D.X.5    Feng, Y.J.6
  • 29
    • 84976384379 scopus 로고    scopus 로고
    • Lipoxin A4 preconditioning attenuates intestinal ischemia reperfusion injury through Keap1/Nrf2 pathway in a lipoxin A4 receptor independent manner
    • Han, X., Yao, W., Liu, Z., Li, H., Zhang, Z.J., Hei, Z., Xia, Z., Lipoxin A4 preconditioning attenuates intestinal ischemia reperfusion injury through Keap1/Nrf2 pathway in a lipoxin A4 receptor independent manner. Oxidative Med. Cell. Longev., 2016, 2016, 9303606.
    • (2016) Oxidative Med. Cell. Longev. , vol.2016 , pp. 9303606
    • Han, X.1    Yao, W.2    Liu, Z.3    Li, H.4    Zhang, Z.J.5    Hei, Z.6    Xia, Z.7
  • 31
    • 84955502554 scopus 로고    scopus 로고
    • Ameliorative effect of lotus seedpod proanthocyanidins on cognitive impairment and brain aging induced by D-galactose
    • Gong, Y.S., Guo, J., Hu, K., Gao, Y.Q., Xie, B.J., Sun, Z.D., Yang, E.N., Hou, F.L., Ameliorative effect of lotus seedpod proanthocyanidins on cognitive impairment and brain aging induced by D-galactose. Exp. Gerontol. 74 (2016), 21–28.
    • (2016) Exp. Gerontol. , vol.74 , pp. 21-28
    • Gong, Y.S.1    Guo, J.2    Hu, K.3    Gao, Y.Q.4    Xie, B.J.5    Sun, Z.D.6    Yang, E.N.7    Hou, F.L.8
  • 32
    • 84923105905 scopus 로고    scopus 로고
    • A high dose of short term exogenous D-galactose administration in young male rats produces symptoms simulating the natural aging process
    • Haider, S., Liaquat, L., Shahzad, S., Sadir, S., Madiha, S., Batool, Z., Tabassum, S., Saleem, S., Naqvi, F., Perveen, T., A high dose of short term exogenous D-galactose administration in young male rats produces symptoms simulating the natural aging process. Life Sci. 124 (2015), 110–119.
    • (2015) Life Sci. , vol.124 , pp. 110-119
    • Haider, S.1    Liaquat, L.2    Shahzad, S.3    Sadir, S.4    Madiha, S.5    Batool, Z.6    Tabassum, S.7    Saleem, S.8    Naqvi, F.9    Perveen, T.10
  • 33
    • 33947154868 scopus 로고    scopus 로고
    • Quercetin attenuates spontaneous behavior and spatial memory impairment in D-galactose-treated mice by increasing brain antioxidant capacity
    • Sun, S.W., Yu, H.Q., Zhang, H., Zheng, Y.L., Wang, J.J., Luo, L., Quercetin attenuates spontaneous behavior and spatial memory impairment in D-galactose-treated mice by increasing brain antioxidant capacity. Nutr. Res. 27 (2007), 169–175.
    • (2007) Nutr. Res. , vol.27 , pp. 169-175
    • Sun, S.W.1    Yu, H.Q.2    Zhang, H.3    Zheng, Y.L.4    Wang, J.J.5    Luo, L.6
  • 34
    • 84896494310 scopus 로고    scopus 로고
    • Quercetin promotes proliferation and differentiation of oligodendrocyte precursor cells after oxygen/glucose deprivation-induced injury
    • Wu, X., Qu, X., Zhang, Q., Dong, F., Yu, H., Yan, C., Qi, D., Wang, M., Liu, X., Yao, R., Quercetin promotes proliferation and differentiation of oligodendrocyte precursor cells after oxygen/glucose deprivation-induced injury. Cell. Mol. Neurobiol. 34 (2014), 463–471.
    • (2014) Cell. Mol. Neurobiol. , vol.34 , pp. 463-471
    • Wu, X.1    Qu, X.2    Zhang, Q.3    Dong, F.4    Yu, H.5    Yan, C.6    Qi, D.7    Wang, M.8    Liu, X.9    Yao, R.10
  • 35
    • 0036238915 scopus 로고    scopus 로고
    • The role of apoptosis in the normal aging brain, skeletal muscle, and heart
    • Pollack, M., Phaneuf, S., Dirks, A., Leeuwenburgh, C., The role of apoptosis in the normal aging brain, skeletal muscle, and heart. Ann. N. Y. Acad. Sci. 959 (2002), 93–107.
    • (2002) Ann. N. Y. Acad. Sci. , vol.959 , pp. 93-107
    • Pollack, M.1    Phaneuf, S.2    Dirks, A.3    Leeuwenburgh, C.4
  • 37
    • 1342333859 scopus 로고    scopus 로고
    • Oxidative stress-induced apoptosis is associated with alterations in mitochondrial caspase activity and Bcl-2-dependent alterations in mitochondrial pH (pH(m))
    • Takahashi, A., Masuda, A., Sun, M., Centonze, V.E., Herman, B., Oxidative stress-induced apoptosis is associated with alterations in mitochondrial caspase activity and Bcl-2-dependent alterations in mitochondrial pH (pH(m)). Brain Res. Bull. 62 (2004), 497–504.
    • (2004) Brain Res. Bull. , vol.62 , pp. 497-504
    • Takahashi, A.1    Masuda, A.2    Sun, M.3    Centonze, V.E.4    Herman, B.5
  • 38
    • 70349333698 scopus 로고    scopus 로고
    • The Nrf2-ARE cytoprotective pathway in astrocytes
    • Vargas, M.R., Johnson, J.A., The Nrf2-ARE cytoprotective pathway in astrocytes. Expert Rev. Mol. Med., 11, 2009.
    • (2009) Expert Rev. Mol. Med. , vol.11
    • Vargas, M.R.1    Johnson, J.A.2
  • 39
    • 84884884530 scopus 로고    scopus 로고
    • Therapeutic roles of heme oxygenase-1 in metabolic diseases: curcumin and resveratrol analogues as possible inducers of heme oxygenase-1
    • Son, Y., Lee, J.H., Chung, H.T., Pae, H.O., Therapeutic roles of heme oxygenase-1 in metabolic diseases: curcumin and resveratrol analogues as possible inducers of heme oxygenase-1. Oxidative Med. Cell. Longev., 2013, 2013, 639541.
    • (2013) Oxidative Med. Cell. Longev. , vol.2013 , pp. 639541
    • Son, Y.1    Lee, J.H.2    Chung, H.T.3    Pae, H.O.4
  • 40
    • 79952276580 scopus 로고    scopus 로고
    • Heme oxygenase-1 in tumor biology and therapy
    • Was, H., Dulak, J., Jozkowicz, A., Heme oxygenase-1 in tumor biology and therapy. Curr. drug targets 11 (2010), 1551–1570.
    • (2010) Curr. drug targets , vol.11 , pp. 1551-1570
    • Was, H.1    Dulak, J.2    Jozkowicz, A.3


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